In this study, we use a genetic algorithm and k-nearest neighbor method to classify two subtypes of renal cell carcinoma using a set of microarray gene expression profiles of nine samples (three clear cell tumors and ...
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In this study, we use a genetic algorithm and k-nearest neighbor method to classify two subtypes of renal cell carcinoma using a set of microarray gene expression profiles of nine samples (three clear cell tumors and six papillary tumors). We show that the genetic algorithm/k-nearest neighbor method can be efficiently used in identifying a panel of discriminator genes. To test the robustness of the algorithm, we perform a bootstrapping analysis that removes one sample from the data set at a time and uses the remaining samples for gene selection. We show that each of the removed samples can be classified correctly. We also analyze the stability of the algorithm and the sensitivity of the algorithm with respect to different samples.
For the measurement of biomedical signals in the under body, a miniaturized implantable wireless telemetry system is implemented. This overall system consists of a charging system, an IR receiver, a multi-channel sign...
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ISBN:
(纸本)0780387309
For the measurement of biomedical signals in the under body, a miniaturized implantable wireless telemetry system is implemented. This overall system consists of a charging system, an IR receiver, a multi-channel signal processor and a FM transmitter. All the parts are packed in the titanium case of which size is 50(L)/spl times/27(W)/spl times/7(H) mm. To control the implanted device at the external body and utilize the advantages of the simplification of circuit structure and the reduction of power consumption, an infrared wireless communication method has been adopted. The implements system uses a unique data protocol to prevent the interferences from other infrared remote control of the household appliances. The surface of the implanted device has been coated by biocompatible material to be implanted in the body. This system can be applied to measurements system of various kinds of bio-signals such as bio-electrical, bio-chemical and bio-mechanical signals, including EMG, ECG, insulin level, blood pressure signal etc.
In this paper the miniaturized microphone unit that can be utilized to the implantable middle car and inner ear is designed and implemented. The implantable microphone unit that planed to set up in the center of the p...
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ISBN:
(纸本)0780387309
In this paper the miniaturized microphone unit that can be utilized to the implantable middle car and inner ear is designed and implemented. The implantable microphone unit that planed to set up in the center of the pinna has been designed to ensure the necessary dynamic range and to improve the sensitivity of microphone unit. In addition to, the microphone unit is miniaturized and its biocompatibility of human body is considered. The microphone unit is composed of a minimized electric microphone, a titanium case which has 5.3 mm diameter and 3.7 mm height, a SUS316L vibrating membrane of 10 /spl mu/m thickness which is touched with a hypodermic tissue and adopted for the less attenuation of microphone sensitivity. Through the experiments of the fabricated microphone unit, it is verified that the implemented microphone unit operates up to the bandwidth of 5 kHz without declining of sensitivity in the 6 mm hypodermic tissue.
Since humans are bipedal, it is easy to become bedridden when the hip and legs become weakened or disabled due to aging or other causes. If such physically challenged people are enabled to get up from bed and move to ...
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The key to the successful simulation of deformable objects is to model the realistic behavior of deformation when they are influenced by intricate contact conditions and geometric constraints. This paper describes con...
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Virtual environments (VEs) allow users to experience and interact with a rich sensory environment, but most virtual worlds contain only sensory information similar to that which we experience in the physical world. In...
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In 1997, the European Paediatric Orthopaedic Society (EPOS) initiated an international survey of musculoskeletal problems in individuals with Down syndrome. The goals of the study were far-reaching and ambitious in or...
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In 1997, the European Paediatric Orthopaedic Society (EPOS) initiated an international survey of musculoskeletal problems in individuals with Down syndrome. The goals of the study were far-reaching and ambitious in order to obtain a clear picture of the variety of orthopedic problems associated with Down syndrome, to relate their occurrence to other medical conditions, and to record and compare methods of treatment. The survey was to be international in scope, including orthopedic surgeons and departments across Europe and outside Europe. The study was coordinated from the Tel Aviv University in Israel as a multicenter study using electronic technology. This paper describes the organization and implementation of the EPOS Down Syndrome Survey, with special emphasis on the sophisticated electronic data entry instrument that was developed especially for the survey. It is concluded that computerized data entry forms like the one that we developed for the EPOS Down Syndrome Survey are valuable tools for medical surveys. They are especially important for multicenter and multinational studies.
Classroom BRIDGE supports activity awareness by facilitating planning and goal revision in collaborative, project-based middle school science. It integrates large-screen and desktop views of project times to support i...
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Paper Augmented Digital Documents (PADDs) are digital documents that can be manipulated either on a computer screen or on paper. PADDs, and the infrastructure supporting them, can be seen as a bridge between the digit...
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In many organizations, collaborating with peers, sharing resources, and codifying know-how are not typical facets of work activity. For such organizations, knowledge management support must help people identify and or...
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