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Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

作者： F. Babiloni F. Cincotti M. Mattiocco A. Timperi S. Salinari M.G. Marciani M. Donatella Department of Human Physiology and Pharmacology University of Roma La Sapienza Rome Italy Fondazione Santa Lucia IRCCS Rome Italy Department of Computer and Systems Science University of Roma La Sapienza Rome Italy Department of Neuroscience University of Roma Tor Vergata Rome Italy

The aim of this paper is to analyze whether the use of the cortical activity estimated from non invasive EEG recordings could be useful to detect mental states related to the imagination of limb movements. Estimation of cortical activity was performed on high resolution EEG data related to the imagination of limb movements gathered in five normal healthy subjects by using realistic head models. Cortical activity was estimated in region of interest associated with the subject's Brodmann areas by using depth-weighted minimum norm solutions. Comparisons between surface recorded EEG and the estimated cortical activity were performed. The estimated cortical activity related to the mental imagery of limbs in the five subjects is located mainly over the contralateral primary motor area. The unbalance between brain activity estimated in contralateral and ipsilateral motor cortical areas relative to the finger movement imagination is greater than those obtained in the scalp EEG recordings. Results suggest that the use of the estimated cortical activity for the motor imagery of upper limbs could be potentially superior with respect to the use of surface EEG recordings. This is due to a greater statistically significant unbalance between the activity estimated in the contralateral and ipsilateral hemisphere with respect to those observed with surface EEG. These results are useful in the context of the development of a non invasive brain computer interface.

关键词： Brain computer interfaces Electroencephalography Image resolution Fingers Current density Image analysis State estimation Magnetic heads Brain modeling Scalp

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Tactile gloves for autonomous grasping with the NASA/DARPA Robonaut

Tactile gloves for autonomous grasping with the NASA/DARPA R...

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IEEE International Conference on Robotics and Automation (ICRA)

作者： T.B. Martin R.O. Ambrose M.A. Diftler R. Platt M.J. Butzer Automation Robotics and Simulation Division NASA-Johnson Space Center Houston TX USA Department of Computer Science University of Massachusetts Amherst MA USA Human Space Flight Programs Oceaneering Space Systems Houston TX USA

Tactile data from rugged gloves are providing the foundation for developing autonomous grasping skills for the NASA/DARPA Robonaut, a dexterous humanoid robot. These custom gloves compliment the human like dexterity available in the Robonaut hands. Multiple versions of the gloves are discussed, showing a progression in using advanced materials and construction techniques to enhance sensitivity and overall sensor coverage. The force data provided by the gloves can be used to improve dexterous, tool and power grasping primitives. Experiments with the latest gloves focus on the use of tools, specifically a power drill used to approximate an astronaut's torque tool.

关键词： NASA humans Grasping Robotics and automation humanoid robots Robot sensing systems Force sensors Sensor phenomena and characterization Control systems Orbital robotics

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Application of genetic algorithm/k-nearest neighbor method to the classification of renal cell carcinoma

Application of genetic algorithm/k-nearest neighbor method t...

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Proceedings of the IEEE Computational Systems Bioinformatics Conference, CSB

作者： Dongqing Liu Ting Shi J.A. DiDonato J.D. Carpten Jianping Zhu Zhong-Hui Duan Department of Computer Science University of Akron Akron OH USA Department of Cancer Biology Cleveland Clinic Foundation Cleveland OH USA Genetic Basis of Human Disease Research Division Translational Genomics Research Institute Phoenix Tempe AZ USA Department of Theoretical and Applied Mathematics University of Akron Akron OH USA

In this study, we use a genetic algorithm and k-nearest neighbor method to classify two subtypes of renal cell carcinoma using a set of microarray gene expression profiles of nine samples (three clear cell tumors and six papillary tumors). We show that the genetic algorithm/k-nearest neighbor method can be efficiently used in identifying a panel of discriminator genes. To test the robustness of the algorithm, we perform a bootstrapping analysis that removes one sample from the data set at a time and uses the remaining samples for gene selection. We show that each of the removed samples can be classified correctly. We also analyze the stability of the algorithm and the sensitivity of the algorithm with respect to different samples.

关键词： Genetic algorithms Biological cells Network-on-a-chip Cells (biology) Genetic mutations Bioinformatics Gene expression Neoplasms Testing Robustness

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Design of implantable wireless biomedical signals telemetry system

Design of implantable wireless biomedical signals telemetry ...

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Annual Conference of Industrial Electronics Society

作者： Young-Ho Yoon Eui-Sung Jung Ho-Kyung Kang Min-Kyu Kim Byung-Seop Song Jin-Ho Cho Advanced Research Center for Recovery of Human Sensibility Kyungpook National University Daegu South Korea School of Electrical Engineering & Computer Science Kyungpook National University Daegu South Korea Department of Biological & Medical Engineering School of Medicine Kyungpook National University Daegu South Korea

ISBN: (纸本)0780387309

For the measurement of biomedical signals in the under body, a miniaturized implantable wireless telemetry system is implemented. This overall system consists of a charging system, an IR receiver, a multi-channel signal processor and a FM transmitter. All the parts are packed in the titanium case of which size is 50(L)/spl times/27(W)/spl times/7(H) mm. To control the implanted device at the external body and utilize the advantages of the simplification of circuit structure and the reduction of power consumption, an infrared wireless communication method has been adopted. The implements system uses a unique data protocol to prevent the interferences from other infrared remote control of the household appliances. The surface of the implanted device has been coated by biocompatible material to be implanted in the body. This system can be applied to measurements system of various kinds of bio-signals such as bio-electrical, bio-chemical and bio-mechanical signals, including EMG, ECG, insulin level, blood pressure signal etc.

关键词： Signal design Telemetry Biomedical measurements Communication system control Optical receivers Signal processing Transmitters Titanium Circuits Energy consumption

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Implementation of miniaturized microphone unit for implantable hearing aid and its characteristics

Implementation of miniaturized microphone unit for implantab...

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Annual Conference of Industrial Electronics Society

作者： Min-Kyu Kim Ji-Hun Han Young-Ho Yoon Byung-Seop Song Jin-Ho Cho Department of Biological & Medical Engineering School of Medicine Kyungpook National University Daegu South Korea School of Electrical Engineering & Computer Science Kyungpook National University Daegu South Korea Advanced Research Center for Recovery of Human Sensibility Kyungpook National University Daegu South Korea

ISBN: (纸本)0780387309

In this paper the miniaturized microphone unit that can be utilized to the implantable middle car and inner ear is designed and implemented. The implantable microphone unit that planed to set up in the center of the pinna has been designed to ensure the necessary dynamic range and to improve the sensitivity of microphone unit. In addition to, the microphone unit is miniaturized and its biocompatibility of human body is considered. The microphone unit is composed of a minimized electric microphone, a titanium case which has 5.3 mm diameter and 3.7 mm height, a SUS316L vibrating membrane of 10 /spl mu/m thickness which is touched with a hypodermic tissue and adopted for the less attenuation of microphone sensitivity. Through the experiments of the fabricated microphone unit, it is verified that the implemented microphone unit operates up to the bandwidth of 5 kHz without declining of sensitivity in the 6 mm hypodermic tissue.

关键词： Microphones Auditory system Ear Hearing aids Deafness humans Signal processing Bones Dynamic range Organizing

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Self-Assisted Care System for human Mobility

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Journal of Robotics and Mechatronics 2004年第5期16卷 464-472页

作者： Onishi, Teruhisa Arai, Tatsuo Inoue, Kenji Mae, Yasushi Department of Electronics and Computer Engineering Tsuyama National College of Technology 624-1 Numa Tsuyama Okayama708-8509 Japan Department of Systems Innovation Graduate School of Engineering Science Osaka University 1-3 Machikaneyama Toyonaka Osaka560-8531 Japan Department of Human and Artificial Intelligence Systems Faculty of Engineering University of Fukui 3-9-1 Bunkyo Fukui910-8507 Japan

Since humans are bipedal, it is easy to become bedridden when the hip and legs become weakened or disabled due to aging or other causes. If such physically challenged people are enabled to get up from bed and move to a nearby location, however, they could use their arms and hands to do certain tasks such as taking meals or writing. In this paper, we propose a wearable device for supporting the human body that can be easily worn or removed by means of a body-holding device. The hoisting device has an arm which, as an end-effector, supports the body and allows the user to rise from bed and lie down again. In addition, a three-point fixing mechanism is used to maintain the user’s sitting posture at a desk, and to realize an integrated self-assisted care system. © 2004, Fuji Technology Press. All rights reserved.

关键词： Wearable technology

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Constraint-based contact analysis between deformable objects

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4th International Conference on Computational science, ICCS 2004

作者： Hong, Min Choi, Min-Hyung Lee, Chris Bioinformatics University of Colorado Health Sciences Center 4200 E. 9th Avenue Campus Box C-245 DenverCO80262 United States Department of Computer Science and Engineering University of Colorado at Denver Campus Box 109 PO Box 173364 DenverCO80217 United States Center for Human Simulation University of Colorado Health Sciences Center P.O. Box 6508 Mail Stop F-435 AuroraCO80045 United States

ISBN: (纸本)3540221158

The key to the successful simulation of deformable objects is to model the realistic behavior of deformation when they are influenced by intricate contact conditions and geometric constraints. This paper describes constraint- based contact modeling between deformable objects using a nonlinear finite element method. In contrast to the penalty force based approaches, constraint- based enforcement of contact provide accuracy and freedom from finding proper penalty coefficients. This paper is focused on determining contact regions and calculating reaction forces at appropriate nodes and elements within the contact regions. The displacement and deformation of all nodes are dynamically updated based on the contact reaction forces. Our constraint based contact force computation method guarantees tight error bound at the contact regions and maintains hard constraints without overshoot or oscillation at the boundaries. In addition, the proposed method doesn't require us to choose proper penalty coefficients, thus greater numerical stability can be achieved and generally large integration steps can be utilized for the ODE solver. Contact conditions are formulated as nonlinear equality and inequality constraints and the force computation is cast into a nonlinear optimization problem. Our rigidto- deformable and deformable-to-deformable contact simulation demonstrates that the non-penetration constraints are well maintained. © Springer-Verlag Berlin Heidelberg 2004.

关键词： Deformation

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Information-rich virtual environments: Theory, tools, and research agenda 03

Information-rich virtual environments: Theory, tools, and re...

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2003 ACM Symposium on Virtual Reality Software and Technology, VRST 2003

作者： Bowman, Doug A. North, Chris Chen, Jian Polys, Nicholas F. Pyla, Pardha S. Yilmaz, Umur Department of Computer Science Center for Human-Computer Interaction Virginia Tech BlacksburgVA United States

ISBN: (纸本)1581135696

Virtual environments (VEs) allow users to experience and interact with a rich sensory environment, but most virtual worlds contain only sensory information similar to that which we experience in the physical world. Information-rich virtual environments (IRVEs) combine the power of VEs and information visualization, augmenting VEs with additional abstract information such as text, numbers, or graphs. IRVEs can be useful in many contexts, such as education, medicine, or construction. In our work, we are developing a theoretical foundation for the study of IRVEs and tools for their development and evaluation. We present a working definition of IRVEs, a discussion of information display and interaction in IRVEs. We also describe a software framework for IRVE development and a testbed enabling evaluation of text display techniques for IRVEs. Finally, we present a research agenda for this area. Copyright © 2003 ACM.

关键词： Virtual reality

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Design and Implementation of a Multinational computerized Patient Survey: The European Paediatric Orthopaedic Society Down Syndrome Survey

TheScientificWorldJournal

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TheScientificWorldJournal 2004年第1期4卷 256-263页

作者： David M Steinberg Moshe Kaplan Joav Merrick Shlomo Wientroub Department of Statistics and Operations Research Tel Aviv University Israel. School of Computer Science Tel Aviv University Israel. National Institute of Child Health and Human Development Office of the Medical Director Division for Mental Retardation Ministry of Social Affairs Jerusalem and Zusman Child Development Center and Divisions of Pediatrics and Community Health Ben Gurion University Beer-Sheva Israel. Department of Pediatric Orthopaedics Dana Children's Hospital Sourasky Medical Center Sackler School of Medicine Tel Aviv University Israel.

In 1997, the European Paediatric Orthopaedic Society (EPOS) initiated an international survey of musculoskeletal problems in individuals with Down syndrome. The goals of the study were far-reaching and ambitious in order to obtain a clear picture of the variety of orthopedic problems associated with Down syndrome, to relate their occurrence to other medical conditions, and to record and compare methods of treatment. The survey was to be international in scope, including orthopedic surgeons and departments across Europe and outside Europe. The study was coordinated from the Tel Aviv University in Israel as a multicenter study using electronic technology. This paper describes the organization and implementation of the EPOS Down Syndrome Survey, with special emphasis on the sophisticated electronic data entry instrument that was developed especially for the survey. It is concluded that computerized data entry forms like the one that we developed for the EPOS Down Syndrome Survey are valuable tools for medical surveys. They are especially important for multicenter and multinational studies.

关键词： Down syndrome Israel human development multinational computerized patient survey musculoskeletal problems pediatric orthopedics public health

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Classroom BRIDGE: Using collaborative public and desktop timelines to support activity awareness

Classroom BRIDGE: Using collaborative public and desktop tim...

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UIST'03: Proceedings of the 16th Annual ACM Symposium on User Interface Software and Technology

作者： Ganoe, Craig H. Somervell, Jacob P. Neale, Dennis C. Isenhour, Philip L. Carroll, John M. Rosson, Mary Beth McCrickard, D. Scott Center for Human Computer Interaction Computer Science Department Virginia Polytechnic Institute and State University Blacksburg VA 24061

Classroom BRIDGE supports activity awareness by facilitating planning and goal revision in collaborative, project-based middle school science. It integrates large-screen and desktop views of project times to support incidental creation of awareness information through routine document transactions, integrated presentation of awareness information as part of workspace views, and public access to subgroup activity. It demonstrates and develops an object replication approach to integrating synchronous and asynchronous distributed work for a platform incorporating both desktop and large-screen devices. This paper describes an implementation of these concepts with preliminary evaluation data, using timeline-based user interfaces. © 2003 ACM.

关键词： computer supported cooperative work

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