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arXiv 2022年

作者： Monsalve-Bravo, Gloria M. Lawson, Brodie A.J. Drovandi, Christopher Burrage, Kevin Brown, Kevin S. Baker, Christopher M. Vollert, Sarah A. Mengersen, Kerrie McDonald-Madden, Eve Adams, Matthew P. School of Earth and Environmental Sciences The University of Queensland St LuciaQLD4072 Australia Centre for Biodiversity and Conservation Science The University of Queensland St LuciaQLD4072 Australia School of Chemical Engineering The University of Queensland St LuciaQLD4072 Australia Centre for Data Science Queensland University of Technology BrisbaneQLD4001 Australia ARC Centre of Excellence for Mathematical and Statistical Frontiers Queensland University of Technology BrisbaneQLD4001 Australia School of Mathematical Sciences Queensland University of Technology BrisbaneQLD4001 Australia ARC Centre of Excellence for Plant Success in Nature and Agriculture Queensland University of Technology BrisbaneQLD4001 Australia Department of Computer Science University of Oxford OxfordOX1 3QD United Kingdom Department of Pharmaceutical Sciences Oregon State University CorvallisOR97331 United States Department of Chemical Biological & Environmental Engineering Oregon State University CorvallisOR97331 United States School of Mathematics and Statistics The University of Melbourne ParkvilleVIC3010 Australia Melbourne Centre for Data Science The University of Melbourne ParkvilleVIC3010 Australia Centre of Excellence for Biosecurity Risk Analysis The University of Melbourne ParkvilleVIC3010 Australia

This work introduces a comprehensive approach to assess the sensitivity of model outputs to changes in parameter values, constrained by the combination of prior beliefs and data. This novel approach identifies stiff parameter combinations strongly affecting the quality of the model-data fit while simultaneously revealing which of these key parameter combinations are informed primarily by the data or are also substantively influenced by the priors. We focus on the very common context in complex systems where the amount and quality of data are low compared to the number of model parameters to be collectively estimated, and showcase the benefits of this technique for applications in biochemistry, ecology, and cardiac electrophysiology. We also show how stiff parameter combinations, once identified, uncover controlling mechanisms underlying the system being modeled and inform which of the model parameters need to be prioritized in future experiments for improved parameter inference from collective model-data fitting. Copyright © 2022, The Authors. All rights reserved.

关键词： Uncertainty analysis

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Correction: Extremely boosted neural network for more accurate multi-stage Cyber attack prediction in cloud computing environment

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Journal of Cloud Computing 2023年第1期12卷 1-1页

作者： Dalal, Surjeet Manoharan, Poongodi Kumar, Lilhore Umesh Seth, Bijeta alsekait, Deema Mohammed Simaiya, Sarita Hamdi, Mounir Raahemifar, Kaamran Department of Computer Science and Engineering Amity University Haryana Gurugram India Division of Information and Computing Technology College of Science and Engineering Hamad Bin Khalifa University Qatar Foundation Doha Qatar School of Computing University of Louisiana Lafayette USA Department of Computer Science and Engineering Chandigarh University Mohali India Department of Computer Science and Engineering B. M. Institute of Engineering & Technology Sonipat India Department of Computer Science and Information Technology Applied College Princess Nourah Bint Abdulrahman University Riyadh Saudi Arabia College of Information Sciences and Technology Data Science and Artificial Intelligence Program State College USA School of Optometry and Vision Science Faculty of Science University of Waterloo Waterloo Canada Faculty of Engineering University of Waterloo Waterloo Canada

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基于大语言模型的糖尿病管理:潜力与展望

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science Bulletin 2024年第5期69卷 583-588页

作者：盛斌管洲榆 Lee-Ling Lim 江泽铧 Nestoras Mathioudakis 李佳佳刘茹涵包玉倩 Yong Mong Bee 王亚星郑颖丰 Gavin Siew Wei Tan 纪宏伟 Josip Car 王海波 David C.Klonoff 李华婷覃宇宗黄天荫贾伟平 Shanghai International Joint Laboratory of Intelligent Prevention and Treatment for Metabolic Diseases Department of Computer Science and EngineeringSchool of ElectronicInformationand Electrical EngineeringShanghai Jiao Tong UniversityDepartment of Endocrinology and MetabolismShanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai Diabetes InstituteShanghai Clinical Center for DiabetesShanghai 200240China MOE Key Laboratory of Artificial Intelligence Artificial Intelligence InstituteShanghai Jiao Tong UniversityShanghai 200240China Department of Medicine Faculty of MedicineUniversity of MalayaKuala Lumpur 50603Malaysia Department of Medicine and Therapeutics The Chinese University of Hong KongHong KongChina Asia Diabetes Foundation Hong KongChina Tsinghua Medicine of Tsinghua University Beijing 100084China School of Clinical Medicine Beijing Tsinghua Changgung HospitalBeijing 102218China Division of Endocrinology Diabetes&MetabolismJohns Hopkins University School of MedicineBaltimoreMD 21211USA Department of Endocrinology Singapore General HospitalSingapore 169608Singapore Beijing Institute of Ophthalmology Beijing Tongren HospitalCapital University of Medical ScienceBeijing Ophthalmology and Visual Sciences Key LaboratoryBeijing 100730China State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangzhou 510060China Singapore Eye Research Institute Singapore National Eye CentreSingapore 168751Singapore Department of Cardiology the Affiliated Hospital of Qingdao UniversityQingdao 266011China Centre for Population Health Sciences Lee Kong Chian School of MedicineNanyang Technological University SingaporeSingapore 639798Singapore Department of Primary Care and Public Health School of Public HealthImperial College LondonLondon SW72BUUK Clinical Trial Unit Research Centre of Big Data and Artificial Intelligence in Medicine

The increasing prevalence of diabetes has become a global public health concern in the 21st *** 2021,it was estimated that 537 million people had diabetes,and this number is projected to reach 643 million by 2030,and 783 million by 2045[1].Such a huge burden of diabetes brings great challenges in its prevention and management,including early diagnosis,timely interventions,and regular monitoring of risk factor control and complications *** self-care support and patient empowerment can enhance clinical and psychobehavioural outcomes[2],although these require additional resources including manpower,infrastructure(hard and technology),and *** emergence of digital health technologies(DHTs),especially artificial intelligence(AI),may help address these obstacles and alleviate the burden of diabetes[3].Large language models(LLMs),a generative AI that can accept image and text inputs and produce text outputs,have shown promise in various aspects of medical care.

关键词： prevention diagnosis finance

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Homogenisation for the monodomain model in the presence of microscopic fibrotic structures

arXiv

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arXiv 2020年

作者： Lawson, Brodie A.J. dos Santos, Rodrigo Weber Turner, Ian W. Bueno-Orovio, Alfonso Burrage, Pamela Burrage, Kevin Centre for Data Science Queensland University of Technology QLD Australia ARC Centre of Excellence for Mathematical and Statistical Frontiers Queensland University of Technology QLD Australia Graduate Program on Computational Modeling Universidade de Juiz de Fora Minas Gerais Brazil Department of Computer Science University of Oxford Oxfordshire United Kingdom

MSC Codes 35B27Computational models in cardiac electrophysiology are notorious for long runtimes, restricting the numbers of nodes and mesh elements in the numerical discretisations used for their solution. This makes it particularly challenging to incorporate structural heterogeneities on small spatial scales, preventing a full understanding of the critical arrhythmogenic effects of conditions such as cardiac fibrosis. In this work, we explore the technique of homogenisation by volume averaging for the inclusion of non-conductive micro-structures into larger-scale cardiac meshes with minor computational overhead. Importantly, our approach is not restricted to periodic patterns, enabling homogenised models to represent, for example, the intricate patterns of collagen deposition present in different types of fibrosis. We first highlight the importance of appropriate boundary condition choice for the closure problems that define the parameters of homogenised models. Then, we demonstrate the technique’s ability to correctly upscale the effects of fibrotic patterns with a spatial resolution of 10 µm into much larger numerical mesh sizes of 100-250 µm. The homogenised models using these coarser meshes correctly predict critical pro-arrhythmic effects of fibrosis, including slowed conduction, source/sink mismatch, and stabilisation of re-entrant activation patterns. As such, this approach to homogenisation represents a significant step towards whole organ simulations that unravel the effects of microscopic cardiac tissue heterogeneities. © 2020, CC BY.

关键词： Heart

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Principles for data analysis workflows

arXiv

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arXiv 2020年

作者： Stoudt, Sara Vásquez, Váleri N. Martinez, Ciera C. Berkeley Institute for Data Science University of California Berkeley BerkeleyCA United States Statistical & Data Sciences Program Smith College NorthamptonMA United States Energy and Resources Group University of California Berkeley BerkeleyCA United States Department of Molecular and Cellular Biology University of California Berkeley BerkeleyCA United States

Traditional data science education often omits training on research workflows: the process that moves a scientific investigation from raw data to coherent research question to insightful contribution. In this paper, we elaborate basic principles of a reproducible data analysis workflow by defining three phases: the Exploratory, Refinement, and Polishing Phases. Each workflow phase is roughly centered around the audience to whom research decisions, methodologies, and results are being immediately communicated. Importantly, each phase can also give rise to a number of research products beyond traditional academic publications. Where relevant, we draw analogies between principles for data-intensive research workflows and established practice in software development. The guidance provided here is not intended to be a strict rulebook;rather, the suggestions for practices and tools to advance reproducible, sound data-intensive analysis may furnish support for both students and current professionals. Copyright © 2020, The Authors. All rights reserved.

关键词： data handling

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Spatiotemporal analysis of urban heatwaves using tukey g-and-h random field models

arXiv

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arXiv 2020年

作者： Murakami, Daisuke Peters, Gareth W. Matsui, Tomoko Yamagata, Yoshiki Department of Data Science Institute of Statistical Mathematics 10-3 Midoricho Tokyo190-8562 Japan School of Mathematical and Computer Sciences Heriot-Watt University EdinburghEH14 4AS United Kingdom Department of Statistical Modeling Institute of Statistical Mathematics 10-3 Midoricho Tokyo190-8562 Japan Center for Global Environmental Research National Institute for Environmental Studies 16-2 Onogawa Ibaraki305-8506 Japan

The statistical quantification of temperature processes for the analysis of urban heat island (UHI) effects and local heat-waves is an increasingly important application domain in smart city dynamic modelling. This leads to the increased importance of real-time heatwave risk management on a fine grained spatial resolution. This study attempts to analyze and develop new methods for modelling the spatio-temporal behavior of ground temperatures. The developed models consider higher order stochastic spatial properties such as skewness and kurtosis, which are key components for understanding and describing local temperature uctuations and UHI's. The developed models are applied to the greater Tokyo metropolitan area for a detailed real world data case study. The analysis also demonstrates how to statistically incorporate a variety of real data sets. This includes remote sensed imagery and a variety of ground based monitoring site data to build models linking city and urban covariates to air temperature. The air temperature models are then used to capture high resolution spatial emulator outputs for ground surface temperature modelling. The main class of processes studied include the Tukey g-and-h processes for capturing spatial and temporal aspects of heat processes in urban environments. Copyright © 2020, The Authors. All rights reserved.

关键词： Atmospheric temperature

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Roadmap on data-Centric Materials science

arXiv

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arXiv 2024年

作者： Bauer, Stefan Benner, Peter Bereau, Tristan Blum, Volker Boley, Mario Carbogno, Christian Catlow, C.A. Richard Dehm, Gerhard Eibl, Sebastian Ernstorfer, Ralph Fekete, Ádám Foppa, Lucas Fratzl, Peter Freysoldt, Christoph Gault, Baptiste Ghiringhelli, Luca M. Giri, Sajal K. Gladyshev, Anton Goyal, Pawan Hattrick-Simpers, Jason Kabalan, Lara Karpov, Petr Khorrami, Mohammad S. Koch, Christoph Kokott, Sebastian Kosch, Thomas Kowalec, Igor Kremer, Kurt Leitherer, Andreas Li, Yue Liebscher, Christian H. Logsdail, Andrew J. Lu, Zhongwei Luong, Felix Marek, Andreas Merz, Florian Mianroodi, Jaber R. Neugebauer, Jörg Pei, Zongrui Purcell, Thomas A.R. Raabe, Dierk Rampp, Markus Rossi, Mariana Rost, Jan-Michael Saal, James Saalmann, Ulf Sasidhar, Kasturi Narasimha Saxena, Alaukik Sbailò, Luigi Scheidgen, Markus Schloz, Marcel Schmidt, Daniel F. Teshuva, Simon Trunschke, Annette Wei, Ye Weikum, Gerhard Xian, R. Patrick Yao, Yi Yin, Junqi Zhao, Meng Scheffler, Matthias School of Computation Information and Technology Technical University of Munich & Helmholtz AI Munich Germany Max Planck Institute for Dynamics of Complex Technical Systems Magdeburg Germany Institute for Theoretical Physics Heidelberg University Heidelberg Germany Thomas Lord Department of Mechanical Engineering and Materials Science Duke University DurhamNC United States Monash University Department of Data Science and AI Melbourne Australia The NOMAD Laboratory The FHI of the Max-Planck-Gesellschaft IRIS-Adlershof of the Humboldt-Universität zu Berlin Berlin Germany School of Chemistry Cardiff University Cardiff United Kingdom Max-Planck-Institut für Eisenforschung GmbH Düsseldorf Germany Max Planck Computing and Data Facility Garching Germany Institute for Optics and Atomic Physics Technical University of Berlin Berlin Germany Physics Department and IRIS-Adlershof Humboldt Universität zu Berlin Berlin Germany Max Planck Institute of Colloids and Interfaces Potsdam Germany Department of Materials Imperial College London United Kingdom Department of Materials Science and Engineering Friedrich-Alexander Universität Erlangen-Nürnberg Germany Department of Chemistry Northwestern University Illinois United States Humboldt-Universität zu Berlin Department of Physics Berlin Germany Department of Materials Science and Engineering University of Toronto Toronto Canada STFC Hartree Centre Daresbury Laboratory Daresbury Warrington United Kingdom Molecular Simulations from First Principles e.V. Berlin Germany Humboldt-Universität zu Berlin Department of Computer Science Berlin Germany Max Planck Institute for Polymer Research Mainz Germany ICFO-Institut de Ciencies Fotoniques The Barcelona Institute of Science and Technology Castelldefels Barcelona Spain Lenovo HPC Innovation Center Stuttgart Germany New York University New York United States University of Arizona Biochemistry Department Arizona United States Max Planck Institute for the Structure an

science is and always has been based on data, but the terms ‘data-centric’ and the ‘4th paradigm’ of materials research indicate a radical change in how information is retrieved, handled and research is performed. It signifies a transformative shift towards managing vast data collections, digital repositories, and innovative data analytics methods. The integration of Artificial Intelligence (AI) and its subset Machine Learning (ML), has become pivotal in addressing all these challenges. This Roadmap on data-Centric Materials science explores fundamental concepts and methodologies, illustrating diverse applications in electronic-structure theory, soft matter theory, microstructure research, and experimental techniques like photoemission, atom probe tomography, and electron microscopy. While the roadmap delves into specific areas within the broad interdisciplinary field of materials science, the provided examples elucidate key concepts applicable to a wider range of topics. The discussed instances offer insights into addressing the multifaceted challenges encountered in contemporary materials research. © 2024, CC BY.

关键词： data Analytics

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International Workshop on Applications of Probability and Statistics to Biology,July 11-13,2019--In Honor of Professor Minping Qian’s 80th Birthday

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Quantitative Biology 2020年第2期8卷 177-186页

作者： Minghua Deng Jianfeng Feng Hong Qian Lin Wan Fengzhu Sun Center for Quantitative Biology Peking UniversityBeijing 100871China LMAM Center for Statistical ScienceSchool of Mathematical SciencesPeking UniversityBeijing 100871China Institute of Science and Technology for Brain-inspired Intelligence Fudan UniversityShanghai 200433China School of Mathematical Sciences Fudan UniversityShanghai 200433China Centre for Computational Systems Biology Fudan UniversityShanghai 200433China Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence at Fudan University Ministry of EducationShanghai 200433China Department of Computer Science University of WarwickCoventryCV47ALUnited Kingdom Department of Applied Mathematics University of WashingtonSeattleWA 98195USA NCMIS Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190China School of Mathematical Sciences University of Chinese Academy of SciencesBeijing 100049China Quantitative and Computational Biology Program University of Southern CaliforniaLos AngelesCA 90089USA

The International Workshop on Applications of Probability and Statistics to Biology(APSB)was successfully held in Shanghai,China,July 11-13,*** workshop was hosted by the Institute of science and Technology for Brain-inspired Intelligence(ISTBI)at Fudan University,and in honor of the 80th birthday of *** Qian of Peking *** of the twenty eight speakers were former students or close collaborators of ***;and there were over eighty participants from all over China and United States.

关键词： Probability speakers ping

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Employing best input SVR robust lost function with nature-inspired metaheuristics in wind speed energy forecasting

IAENG International Journal of Computer Science

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IAENG International Journal of computer science 2020年第3期47卷 572-584页

作者： Caraka, Rezzy Eko Chen, Rung Ching Bakar, Sakhinah Abu Tahmid, Muhammad Toharudin, Toni Pardamean, Bens Huang, Su-Wen College of Informatics Chaoyang University of Technology Taichung City41349 Taiwan School of Mathematical Sciences The National University of Malaysia Bandar Baru Bangi Selangor43600 Malaysia Bioinformatics and Data Science Research Center Bina Nusantara University 11480 Indonesia Manado North Sulawesi91594 Indonesia Department of Statistics Padjadjaran University Jatinagor west java45363 Indonesia Bioinformatics and Data Science Research Center Bina Nusantara University and Computer Science Dept. BINUS Graduate Program-Master of Computer Science Program Bina Nusantara University Jakarta11480 Indonesia Taichung Veterans General Hospital Taiwan

Wind power has been experiencing a quick improvement. Without a doubt, wind is a variable asset that is hard to forecast. For instance, traditionally time series, extra holds are distributed to deal with this uncertainty. This paper presents a comparison of the performance of various Support Vector Regression (SVR) applied to short-term wind power forecasting. The analogy with BORUTA and multivariate adaptive regression splines (MARS) as judge best input and employ genetic algorithm and particle swarm optimization to find best parameter in Support Vector Regression with robust lost function. We measure the accuracy of this models by Symmetric means absolute percentage error (sMAPE) and we get the best model BORUTA-SVR-PSO with sMAPE 2.07155%. Moreover, we measure the energy conversion using Feedback Linearization Control (FLC). © International Association of Engineers.

关键词： Genetic algorithms

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The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels (vol 400, pg 1619, 2022)

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LANCET 2022年第10365期400卷 1766-1766页

作者： Romanello, M. Di Napoli, C. Drummond, P. Institute for Global Health University College London London UK School of Agriculture Policy and Development University of Reading Reading UK Institute for Sustainable Resources University College London London UK Department of Global Health Centre for Health and the Global Environment University of Washington Seattle WA USA UCL Energy Institute University College London London UK Department of Health Sciences University of York York UK Department of Meteorology University of Reading Reading UK Institute for Risk and Disaster Reduction University College London London UK School of Earth and Environment University of Leeds Leeds UK Centre on Climate Change and Planetary Health London School of Hygiene & Tropical Medicine London UK School of Population Health University of Melbourne Melbourne VIC Australia Department of Earth System Science Tsinghua University Beijing China Mercator Research Institute on Global Commons and Climate Change Berlin Germany Department of Environment Climate Change and Health World Health Organization Geneva Switzerland Institute of Environmental Sciences University of Geneva Geneva Switzerland Cardiovascular Epidemiology Unit Department of Public Health & Primary Care University of Cambridge Cambridge UK School of Government University of Birmingham Birmingham UK Economic Analysis of Climate Impacts and Policy Division Centro Euro-Mediterraneo sui Cambiamenti Climatici Venice Italy Institute for Environmental Design and Engineering University College London London UK Natural Resources Institute University of Greenwich London UK Department of Environmental Health Sciences and Yale Center on Climate Change and Health Yale University New Haven CT USA Department of Civil and Environmental Engineering Northeastern University Boston MA USA Department of Fish and Wildlife Conservation Virginia Polytechnic Institute and State University Blacksburg VA USA Department of Geography University College London London UK NU

With advancements in the science of detection and attribution studies, the influence of climate change over many events has now been quantified. Because of the rapidly increasing temperatures, vulnerable populations (adults older than 65 years, and children younger than one year of age) were exposed to 3·7 billion more heatwave days in 2021 than annually in 1986–2005 (indicator 1.1.2), and heat-related deaths increased by 68% between 2000–04 and 2017–21 (indicator 1.1.5), a death toll that was significantly exacerbated by the confluence of the COVID-19 pandemic. Despite the local cooling and overall health benefits of urban greenspaces, only 277 (27%) of 1038 global urban centres were at least moderately green in 2021 (indicator 2.2.3), and the number of households with air conditioning increased by 66% from 2000 to 2020, a maladaptive response that worsens the energy crisis and further increases urban heat, air pollution, and greenhouse gas emissions. [...]millions of people do not have access to the energy needed to keep their homes at healthy temperatures, preserve food and medication, and meet the seventh Sustainable Development Goal (to ensure access to affordable, reliable, sustainable, and modern energy for all). Aggravating this situation even further, governments continue to incentivise fossil fuel production and consumption: 69 (80%) of 86 countries reviewed had net-negative carbon prices (ie, provided a net subsidy to fossil fuels) for a net total of US$400 billion

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