检索结果-内蒙古大学图书馆

Integrated operating room planning and scheduling: an ILP-Based off-line approach for emergency responsiveness at a local hospital in Naples

引用

Soft Computing 2024年第20期28卷 11987-12003页

作者： Boccia, Maurizio Mancuso, Andrea Masone, Adriano Sterle, Claudio Department of Electrical Engineering and Information Technology University of Naples "Federico II" Via Claudio 21 Naples80125 Italy Institute for System Analysis and Computer Science "Antonio Ruberti" National Research Council of Italy via dei Taurini 19 Rome00185 Italy

This paper addresses a real-world Integrated Operating Room Planning and Scheduling (IORPS) problem encountered by a local hospital in Naples, characterized by stringent emergency management constraints, requiring treatment initiation within a 20-minute time-window. We tackle this problem by an original Integer Linear Programming formulation, capable of dealing with different operating room management strategies (open, block and block-modified). Our work differs from conventional cost-focused models by adopting a patient-oriented objective function, aligning with public hospitals obligations. The proposed method has been validated using real-world data provided by the hospital. The performed experimentation demonstrates the efficiency of the approach, capable of determining the optimal solution within an acceptable computation time that aligns with hospital requirements. Moreover, it also highlights the relevance of using our optimization approach to reduce delays in emergency responsiveness. This confirms its practical usage as a substitute for the current manual procedure. © The Author(s) 2024.

关键词： Operating rooms

来源：评论

学校读者我要写书评

暂无评论

Modeling and Optimal Control for Resource Allocation in the Epidemic Monitoring of a Multi-group Population

引用

SN computer science 2024年第1期5卷 121页

作者： Di Giamberardino, Paolo Iacoviello, Daniela Papa, Federico Department of Computer Control and Management Engineering “A. Ruberti” Sapienza University of Rome Via Ariosto 25 Rome 00185 Italy Institute for System Analysis and Computer Science “A. Ruberti” CNR Via dei Taurini 19 Rome 00185 Italy

In the last 3 years, the entire world has been facing the sanitary emergency due to the SARS-CoV2;it has been stressed the mutual interdependence of the human populations, as well as the strong impact of specific conditions, such as age, work, habits, on the disease spread among subgroups of a given population. Moreover, the high percentage of asymptomatic individuals, especially among young subjects, improves the infection spread among groups with higher probability of fatal consequences. The vaccination campaign has strongly contributed to reduce mortality, so bringing the epidemic scenario probably closer to the endemic state. Nevertheless, the loss of the vaccination protection, the appearance of new variants and the mixing of moving people require a surveillance action to reduce new virus waives. By suitable modeling and optimal control design, this paper addresses the planning of a swab test campaign for the surveillance of the disease spread within a given multi-group population, when resource limitation and distinctive epidemiological characteristics of the subgroups are present. The proposed approach, applied on a case study in which the population is split into four groups, stresses the importance of a suitable tuned swab test campaign, saving a significant number of infections (and therefore of human lives), by scheduling the surveillance effort on the different populations. The determination of this kind of control is useful not only in the endemic condition, but also as general surveillance strategy at the beginning of an epidemic spread, with limitations in material and logistic resources. © 2023, The Author(s), under exclusive licence to Springer Nature Singapore Pte Ltd.

关键词： Epidemic monitoring Mathematical modeling of epidemics Optimal control Resource allocation

来源：评论

学校读者我要写书评

暂无评论

Unveiling drug-induced side effects through network-based analysis: An update

Unveiling drug-induced side effects through network-based an...

引用

2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Funari, Alessio Conte, Federica Paci, Paola Sapienza University of Rome Institute for Systems Analysis and Computer Science 'Antonio Ruberti' National Research Council Department of Translational and Precision Medicine Rome Italy National Research Council Institute for Systems Analysis and Computer Science 'Antonio Ruberti' Rome Italy Sapienza University of Rome Department of Computer Control and Management Engineering Rome17177 Italy

ISBN: (纸本)9798350386226

In this article, we propose an updated version of our previously developed model for predicting drug-side effect associations, applied to two case studies: long QT syndrome and asthma. The classifier accepts the name of a specific drug side effect as input and outputs a list of drugs potentially associated with this side effect. By simulating how drug effects propagate within the interactome using the Random Walk with Restart algorithm, the classifier identifies genes potentially associated with the onset of the side effect. Based on the rationale that the more a drug perturbs these genes, the more likely it is to cause the side effect, the model identifies drugs potentially linked to the onset of the side effect. Moreover, the model enables the categorization of drugs into chemical subclasses using the ClassyFire schema, facilitating the analysis of complex side effects, such as asthma, through more specific mechanisms. The results show that the model identifies both drugs known to be associated with certain side effects, as well as drugs not officially reported by the FDA, demonstrating its generalizability and practical relevance. This method is also adaptable for analyzing other side effects. © 2024 IEEE.

关键词： drug side effect network medicine random walk

来源：评论

学校读者我要写书评

暂无评论

Multi-Agent Coordination for a Partially Observable and Dynamic Robot Soccer Environment with Limited Communication 10

Multi-Agent Coordination for a Partially Observable and Dyna...

引用

10th Italian Workshop on Artificial Intelligence and Robotics, AIRO 2023

作者： Affinita, Daniele Volpi, Flavio Spagnoli, Valerio Suriani, Vincenzo Nardi, Daniele Bloisi, Domenico D. Department of Computer Control and Management Engineering Antonio Ruberti Sapienza University of Rome Italy Faculty of Political Science and Sociopsychological Dynamics UNINT University Rome Italy

RoboCup represents an International testbed for advancing research in AI and robotics, focusing on a definite goal: developing a robot team that can win against the human world soccer champion team by the year 2050. To achieve this goal, autonomous humanoid robots' coordination is crucial. This paper explores novel solutions within the RoboCup Standard Platform League (SPL), where a reduction in WiFi communication is imperative, leading to the development of new coordination paradigms. The SPL has experienced a substantial decrease in network packet rate, compelling the need for advanced coordination architectures to maintain optimal team functionality in dynamic environments. Inspired by market-based task assignment, we introduce a novel distributed coordination system to orchestrate autonomous robots' actions efficiently in low communication scenarios. This approach has been tested with NAO robots during official RoboCup competitions and in the SimRobot simulator, demonstrating a notable reduction in task overlaps in limited communication settings. © 2024 Copyright for this paper by its authors.

关键词： Anthropomorphic robots

来源：评论

学校读者我要写书评

暂无评论

AI-Driven Innovations in Healthcare: Bridging Imaging and Genomics for Advanced Disease Insights

AI-Driven Innovations in Healthcare: Bridging Imaging and Ge...

引用

2024 Ital-IA Intelligenza Artificiale - Thematic Workshops, Ital-IA 2024

作者： Adornetto, Carlo Bruno, Pierangela Calimeri, Francesco De Rose, Edoardo Greco, Gianluigi Quarta, Alessandro Department of Mathematics and Computer Science University of Calabria Via Pietro Bucci Rende Italy Department of Computer Control and Management Engineering "Antonio Ruberti" Sapienza University of Rome Via Ariosto 25 Rome Italy

The application of Artificial Intelligence (AI) techniques for analyzing medical images and omics data is revolutionizing the healthcare industry by offering profound insights into various diseases. Achieving precise diagnoses and formulating effective treatment plans, however, demands intricate and multimodal analysis of complex, sensitive, and diverse medical datasets. Recent advancements in Machine Learning and Deep Learning have proven to be formidable in identifying and classifying specific diseases. This paper outlines the current projects undertaken by our research group in this innovative domain. © 2024 Copyright for this paper by its authors.

关键词： Adversarial machine learning

来源：评论

学校读者我要写书评

暂无评论

Beyond the network-based multi-omics data integration in COPD: A pathway-centric analysis

Beyond the network-based multi-omics data integration in COP...

引用

2024 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2024

作者： Sibilio, Pasquale Conte, Federica Paci, Paola Sapienza University of Rome Department of Computer Control and Management Engineering Rome Italy National Research Council Institute for Systems Analysis and Computer Science 'Antonio Ruberti' Rome Italy Karolinska Institutet Stockholm17177 Sweden

ISBN: (纸本)9798350386226

Chronic obstructive pulmonary disease (COPD) is a lung disease causing hundred thousand of death each year worldwide and defined as a respiratory and airflow impairment majorly due to large and small airways dysfunctions. COPD could be considered as a syndrome that includes disease axes of variable pathological and clinical conditions. Despite recent advances, the comprehension of the molecular mechanisms responsible for COPD disease spectrum is far to be reached. Moreover, we should also consider continuous smoking exposure, which could lead to variability in the disease mechanisms and progression. Network-based multi-omics data integration can help to study the association between molecular determinants on diverse biomolecular layers in a disease context. In a previous study, we leveraged lung RNA-seq and DNA-methylation data of a COPD-control cohort to build a correlation-based integrated network (called coupled network), that helped to unveil genes involved in immune and inflammatory modulation of COPD. Therefore, in our previous study we highlighted the most important genes of the coupled network and inspected their single contribution to disease-related pathways. In this study we aim to overcome this limitation by performing a pathway activity analysis by considering the expression and DNA methylation profiles of coupled network genes. Moreover, we exploit this analysis to study the possible contribution of coupled network genes to the differential disease progression between current and former smokers patients. © 2024 IEEE.

关键词： Lung cancer

来源：评论

学校读者我要写书评

暂无评论

Max Flow Vulnerability of Undirected Planar Networks 32

Max Flow Vulnerability of Undirected Planar Networks

引用

32nd Italian Symposium on Advanced Database systems, SEBD 2024

作者： Balzotti, Lorenzo Franciosa, Paolo G. Department of Computer Control and Management Engineering "Antonio Ruberti" Sapienza University of Rome Via Ariosto 25 Rome00185 Italy Department of Statistical Science Sapienza University of Rome p.le Aldo Moro 5 Rome00185 Italy

In the real world, planar networks commonly model utility distribution networks such as gas pipelines, water distribution, city's electric grid, and transportation networks like railways and highways. Evaluating the vulnerability of these networks is crucial on several point of view: in a military context in order to prevent terrorist attack, or for maintenance to prevent wear and tear or natural disasters from inflicting extremely severe damage. This work aims to evaluate the vulnerability of undirected planar network studying the decrease of maximum st-flow when an edge or a vertex is removed, that is, we propose algorithms for computing the max flow vitality of edges and vertices. Our algorithms are applied to real world scenarios, and we prove that high vitality values are well approximated in time close to the time currently required to compute st-max flow O(n log log n). All our algorithms work in O(n) space. © 2024 Copyright for this paper by its authors.

关键词： Natural gas pipelines

来源：评论

学校读者我要写书评

暂无评论

Truthful Matching with Online Items and Offline Agents 50

Truthful Matching with Online Items and Offline Agents

引用

50th International Colloquium on Automata, Languages, and Programming, ICALP 2023

作者： Feldman, Michal Fusco, Federico Mauras, Simon Reiffenhäuser, Rebecca Blavatnik School of Computer Science Tel Aviv University Israel Microsoft Research Herzliya Israel Department of Computer Control and Management Engineering "Antonio Ruberti" Sapienza University of Rome Italy Institute for Logic Language and Computation University of Amsterdam Netherlands

ISBN: (纸本)9783959772785

We study truthful mechanisms for welfare maximization in online bipartite matching. In our (multiparameter) setting, every buyer is associated with a (possibly private) desired set of items, and has a private value for being assigned an item in her desired set. Unlike most online matching settings, where agents arrive online, in our setting the items arrive online in an adversarial order while the buyers are present for the entire duration of the process. This poses a significant challenge to the design of truthful mechanisms, due to the ability of buyers to strategize over future rounds. We provide an almost full picture of the competitive ratios in different scenarios, including myopic vs. non-myopic agents, tardy vs. prompt payments, and private vs. public desired sets. Among other results, we identify the frontier up to which the celebrated e/(e − 1) competitive ratio for the vertex-weighted online matching of Karp, Vazirani and Vazirani extends to truthful agents and online items. © Michal Feldman, Federico Fusco, Simon Mauras, and Rebecca Reiffenhäuser.

关键词： Sales

来源：评论

学校读者我要写书评

暂无评论

Overview of bioinformatic tools to study viral infections

Overview of bioinformatic tools to study viral infections

引用

2023 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2023

作者： Zulian, Verdiana Garbuglia, Anna Rosa Fiscon, Giulia Paci, Paola National Institute for Infectious Diseases Lazzaro Spallanzani Irccs Virology Laboratory Rome Italy Sapienza University of Rome Department of Computer Control and Management Engineering Italy National Research Council Institute for Systems Analysis and Computer Science 'Antonio Ruberti' Rome Italy

ISBN: (纸本)9798350337488

microRNAs play an important role in post-transcriptional gene regulation. Recently, viral microRNAs have been discovered in several viruses, including Hepatitis B virus. This brief work explores bioinformatics tools for viral/host miRNA research and provides insights into the roles of miRNAs in HBV infection, offering an overview of this field, in order to facilitate the selection of the most suitable bioinformatics tools according to individual needs and research goals. © 2023 IEEE.

关键词： bioinformatics tools Hepatitis B virus microRNA target gene

来源：评论

学校读者我要写书评

暂无评论

A Review on the Applications of Transformer-based language models for Nucleotide Sequence Analysis

arXiv

引用

arXiv 2024年

作者： Ghosh, Nimisha Santoni, Daniele Saha, Indrajit Felici, Giovanni Odisha Bhubaneswar India Institute for System Analysis and Computer Science "Antonio Ruberti" National Research Council of Italy Rome Italy Department of Computer Science and Engineering National Institute of Technical Teachers’ Training and Research West Bengal Kolkata India

In recent times, Transformer-based language models are making quite an impact in the field of natural language processing. As relevant parallels can be drawn between biological sequences and natural languages, the models used in NLP can be easily extended and adapted for various applications in bioinformatics. In this regard, this paper introduces the major developments of Transformer-based models in the recent past in the context of nucleotide sequences. We have reviewed and analysed a large number of application-based papers on this subject, giving evidence of the main characterizing features and to different approaches that may be adopted to customize such powerful computational machines. We have also provided a structured description of the functioning of Transformers, that may enable even first time users to grab the essence of such complex architectures. We believe this review will help the scientific community in understanding the various applications of Transformer-based language models to nucleotide sequences. This work will motivate the readers to build on these methodologies to tackle also various other problems in the field of bioinformatics. © 2024, CC BY.

关键词： Nucleotides

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：