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检索条件"机构=Department of Computer Science and the Graduate Program of Computational Modeling"
141 条 记 录,以下是31-40 订阅
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CellBiAge: Improved single-cell age classification using data binarization
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Cell Reports 2023年 第12期42卷 113500页
作者: Yu, Doudou Li, Manlin Linghu, Guanjie Hu, Yihuan Hajdarovic, Kaitlyn H. Wang, An Singh, Ritambhara Webb, Ashley E. Molecular Biology Cell Biology and Biochemistry Graduate Program Brown University Providence 02912 RI United States Data Science Institute Brown University Providence 02912 RI United States Neuroscience Graduate Program Brown University Providence 02912 RI United States Department of Applied Mathematics & Statistics Johns Hopkins University Baltimore 21218 MD United States Department of Computer Science Brown University Providence 02912 RI United States Center for Computational Molecular Biology Brown University Providence 02912 RI United States Department of Molecular Biology Cell Biology and Biochemistry Brown University Providence 02912 RI United States Center on the Biology of Aging Brown University Providence 02912 RI United States Carney Institute for Brain Science Brown University Providence 02912 RI United States Center for Translational Neuroscience Brown University Providence 02912 RI United States
Aging is a major risk factor for many diseases. Accurate methods for predicting age in specific cell types are essential to understand the heterogeneity of aging and to assess rejuvenation strategies. However, classif... 详细信息
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Functional characterization of Alzheimer’s disease genetic variants in microglia
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Nature Genetics 2023年 第10期55卷 1735-1744页
作者: Yang, Xiaoyu Wen, Jia Yang, Han Jones, Ian R. Zhu, Xiaodong Liu, Weifang Li, Bingkun Clelland, Claire D. Luo, Wenjie Wong, Man Ying Ren, Xingjie Cui, Xiekui Song, Michael Liu, Hongjiang Chen, Cady Eng, Nicolas Ravichandran, Mirunalini Sun, Yang Lee, David Van Buren, Eric Jiang, Min-Zhi Chan, Candace S. Y. Ye, Chun Jimmie Perera, Rushika M. Gan, Li Li, Yun Shen, Yin Institute for Human Genetics University of California San Francisco San Francisco CA United States Department of Genetics University of North Carolina Chapel Hill NC United States Pharmaceutical Sciences and Pharmacogenomics Graduate Program University of California San Francisco San Francisco CA United States Helen and Robert Appel Alzheimer’s Disease Research Institute Feil Family Brain and Mind Research Institute Weill Cornell Medicine New York City NY United States Department of Biostatistics University of North Carolina Chapel Hill NC United States Department of Neurology University of California San Francisco San Francisco CA United States Weill Institute for Neurosciences University of California San Francisco San Francisco CA United States Department of Anatomy University of California San Francisco San Francisco CA United States Division of Rheumatology Department of Medicine University of California San Francisco San Francisco CA United States Department of Biostatistics Harvard T.H. Chan School of Public Health Boston MA United States Tetrad Graduate Program University of California San Francisco San Francisco CA United States Rosalind Russell/Ephraim P. Engleman Rheumatology Research Center University of California San Francisco San Francisco CA United States Department of Epidemiology and Biostatistics University of California San Francisco San Francisco CA United States Parker Institute for Cancer Immunotherapy San Francisco CA United States Chan Zuckerberg Biohub San Francisco CA United States Bakar Computational Health Sciences Institute University of California San Francisco San Francisco CA United States Department of Pathology University of California San Francisco San Francisco CA United States Helen Diller Family Comprehensive Cancer Center University of California San Francisco San Francisco CA United States Department of Computer Science University of North Carolina Chapel Hill NC United States
Candidate cis-regulatory elements (cCREs) in microglia demonstrate the most substantial enrichment for Alzheimer’s disease (AD) heritability compared to other brain cell types. However, whether and how these genome-w... 详细信息
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Accurately predicting anticancer peptide using an ensemble of heterogeneously trained classifiers
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Informatics in Medicine Unlocked 2023年 42卷
作者: Azim, Sayed Mehedi Sabab, Noor Hossain Nuri Noshadi, Iman Alinejad-Rokny, Hamid Sharma, Alok Shatabda, Swakkhar Dehzangi, Iman Center for Computational and Integrative Biology Rutgers University Camden 08102 NJ United States Department of Computer Science and Engineering United International University Plot 2 United City Madani Avenue BaddaDhaka 1212 Bangladesh Department of Bioengineering University of California Riverside 92507 CA United States BioMedical Machine Learning Lab The Graduate School of Biomedical Engineering The University of New South Wales (UNSW Sydney) Sydney NSW 2052 Australia UNSW Data Science Hub UNSW Sydney Sydney NSW 2052 Australia Health Data Analytics Program AI-enabled Processes Research Centre Macquarie University Sydney 2109 Australia Institute for Integrated and Intelligent Systems Griffith University Brisbane Australia Laboratory for Medical Science Mathematics RIKEN Center for Integrative Medical Sciences Yokohama 230-0045 Japan Department of Computer Science Rutgers University Camden 08102 NJ United States
The use of therapeutic peptides for the treatment of cancer has received tremendous attention in recent years. Anticancer peptides (ACPs) are considered new anticancer drugs which have several advantages over chemistr... 详细信息
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Homogenisation for the monodomain model in the presence of microscopic fibrotic structures
arXiv
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arXiv 2020年
作者: Lawson, Brodie A.J. dos Santos, Rodrigo Weber Turner, Ian W. Bueno-Orovio, Alfonso Burrage, Pamela Burrage, Kevin Centre for Data Science Queensland University of Technology QLD Australia ARC Centre of Excellence for Mathematical and Statistical Frontiers Queensland University of Technology QLD Australia Graduate Program on Computational Modeling Universidade de Juiz de Fora Minas Gerais Brazil Department of Computer Science University of Oxford Oxfordshire United Kingdom
MSC Codes 35B27computational models in cardiac electrophysiology are notorious for long runtimes, restricting the numbers of nodes and mesh elements in the numerical discretisations used for their solution. This makes... 详细信息
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Stochastic Petri Net Models for the Study of Macrophage Reprogramming
Stochastic Petri Net Models for the Study of Macrophage Repr...
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IEEE International Conference on Bioinformatics and Biomedicine
作者: Elvis H. Ribeiro Alexandre B. Pigozzo Carolina R. Xavier Rodrigo W. dos Santos Marcelo Lobosco Department of Computer Science Federal University of Sao Joao Del Rei Graduate Program in Computational Modeling Federal University of Juiz de Fora
In recent years, Petri nets are being used for modeling complex biological systems. Examples include the modeling of biochemical reactions, protein interaction networks, gene regulation networks and the immune system.... 详细信息
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Physical distancing evaluation for classroom layout management during COVID-19 pandemic era
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AIP Conference Proceedings 2022年 第1期2472卷
作者: Mohd Kamal Mohd Nawawi Ruzelan Khalid Aida Mauziah Benjamin Antoni Wibowo Amalia Zahra 1Institute of Strategic Industrial Decision Modeling School of Quantitative Sciences Universiti Utara Malaysia 06010 UUM Sintok Kedah Malaysia 2Computer Science Department Binus Graduate Program - Master of Computer Science Bina Nusantara University Jakarta Indonesia 11480
Mass gathering has been identified as one of the causes of fast-spreading of COVID-19. Physical distancing practices and large gathering control in Malaysia and all over the world are likely to be continued until the ...
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Parallelized GPU Code of City-Level Large Eddy Simulation
Parallelized GPU Code of City-Level Large Eddy Simulation
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International Symposium on Parallel and Distributed Computing
作者: Daisuke Tsuji Taisuke Boku Ryosaku Ikeda Takuto Sato Hiroto Tadano Hiroyuki Kusaka Department of Computer Science University of Tsukuba Center for Computational Sciences University of Tsukuba Weathernews Inc. (current affiliation) Doctoral Program in Geoenvironmental Sciences Graduate School of Life and Environmental Sciences University of Tsukuba
In this paper, we describe the GPU implementation of our City-LES code, which is developed at the Center for computational sciences (CCS), University of Tsukuba for detailed large eddy simulations, including surface c... 详细信息
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Exponential acceleration of macroscopic quantum tunneling in a Floquet Ising model
arXiv
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arXiv 2023年
作者: Grattan, George Barton, Brandon A. Feeney, Sean Mossi, Gianni Patnaik, Pratik Sagal, Jacob C. Carr, Lincoln D. Oganesyan, Vadim Kapit, Eliot Quantum Engineering Program Colorado School of Mines 1523 Illinois St CO Golden80401 United States Department of Computer Science Colorado School of Mines 1500 Illinois St CO Golden80401 United States Department of Applied Mathematics and Statistics Colorado School of Mines 1500 Illinois St CO Golden80401 United States Department of Physics Colorado School of Mines 1523 Illinois St CO Golden80401 United States KBR Inc. 601 Jefferson St. HoustonTX77002 United States NASA Ames Research Center Moffett FieldCA94035 United States Department of Physics and Astronomy College of Staten Island CUNY Staten IslandNY10314 United States Physics program and Initiative for the Theoretical Sciences The Graduate Center CUNY New YorkNY10016 United States Center for Computational Quantum Physics Flatiron Institute 162 5th Avenue New YorkNY10010 United States
The exponential suppression of macroscopic quantum tunneling (MQT) in the number of elements to be reconfigured is an essential element of broken symmetry phases. Slow MQT is also a core bottleneck in quantum algorith... 详细信息
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Phase transitions in the frustrated Ising ladder with stoquastic and nonstoquastic catalysts
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Physical Review Research 2021年 第4期3卷 043013-043013页
作者: Kabuki Takada Shigetoshi Sota Seiji Yunoki Bibek Pokharel Hidetoshi Nishimori Daniel A. Lidar Department of Physics Tokyo Institute of Technology Yokohama Kanagawa 226-8503 Japan Computational Materials Science Research Team RIKEN Center for Computational Science (R-CCS) Kobe Hyogo 650-0047 Japan Computational Condensed Matter Physics Laboratory RIKEN Cluster for Pioneering Research (CPR) Wako Saitama 351-0198 Japan Computational Quantum Matter Research Team RIKEN Center for Emergent Matter Science (CEMS) Wako Saitama 351-0198 Japan Department of Physics University of Southern California Los Angeles California 90089 USA Center for Quantum Information Science & Technology University of Southern California Los Angeles California 90089 USA Institute of Innovative Research Tokyo Institute of Technology Yokohama Kanagawa 226-8503 Japan Graduate School of Information Sciences Tohoku University Sendai Miyagi 980-8579 Japan RIKEN Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS) Wako Saitama 351-0198 Japan Department of Electrical & Computer Engineering and Department of Chemistry University of Southern California Los Angeles California 90089 USA
The role of nonstoquasticity in the field of quantum annealing and adiabatic quantum computing is an actively debated topic. We study a strongly-frustrated quasi-one-dimensional quantum Ising model on a two-leg ladder... 详细信息
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Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals
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Cell 2025年 第10期188卷 2794-2809.e21页
作者: Mi, Xuelong Chen, Alex Bo-Yuan Duarte, Daniela Carey, Erin Taylor, Charlotte R. Braaker, Philipp N. Bright, Mark Almeida, Rafael G. Lim, Jing-Xuan Ruetten, Virginia M.S. Wang, Yizhi Wang, Mengfan Zhang, Weizhan Zheng, Wei Reitman, Michael E. Huang, Yongkang Wang, Xiaoyu Li, Lei Deng, HanFei Shi, Song-Hai Poskanzer, Kira E. Lyons, David A. Nimmerjahn, Axel Ahrens, Misha B. Yu, Guoqiang Bradley Department of Electrical and Computer Engineering Virginia Polytechnic Institute and State University Arlington 22203 VA United States Janelia Research Campus Howard Hughes Medical Institute Ashburn 20147 VA United States Department of Molecular and Cellular Biology Harvard University Cambridge 02138 MA United States Graduate Program in Neuroscience Harvard Medical School Boston 02115 MA United States Waitt Advanced Biophotonics Center The Salk Institute for Biological Studies La Jolla 92037 CA United States Department of Biochemistry & Biophysics University of California San Francisco San Francisco CA United States Neuroscience Graduate Program University of California San Francisco San Francisco CA United States Centre for Discovery Brain Sciences University of Edinburgh Edinburgh BioQuarter Edinburgh EH16 4SB United Kingdom Gatsby Computational Neuroscience Unit UCL London W1T 4JG United Kingdom Kavli Institute for Fundamental Neuroscience San Francisco CA United States Department of Automation Tsinghua University Beijing 100084 China IDG/McGovern Institute for Brain Research Tsinghua University Beijing 100084 China New Cornerstone Science Laboratory Tsinghua-Peking Center for Life Sciences Beijing Frontier Research Center for Biological Structure School of Life Sciences Tsinghua University Beijing 100084 China State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institutes of Brain Science Fudan University Shanghai 200032 China Beijing National Research Center for Information Science and Technology Beijing 100084 China
Optical recording of intricate molecular dynamics is becoming an indispensable technique for biological studies, accelerated by the development of new or improved biosensors and microscopy technology. This creates maj... 详细信息
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