In this pivotal study, we delve into the imperative realm of Diabetic Retinopathy (DR), a sight-threatening eye disease, introducing a nuanced and comprehensive approach to its detection through cutting-edge deep lear...
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Securing data transmission in a digital era is a difficult one due to the broad application of the Internet, personal computers, and mobile phones for communication. Traditional video steganography techniques sometime...
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Rough set theory places great importance on approximation accuracy,which is used to gauge how well a rough set model describes a target ***,traditional approximation accuracy has limitations since it varies with chang...
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Rough set theory places great importance on approximation accuracy,which is used to gauge how well a rough set model describes a target ***,traditional approximation accuracy has limitations since it varies with changes in the target concept and cannot evaluate the overall descriptive ability of a rough set *** overcome this,two types of average approximation accuracy that objectively assess a rough set model’s ability to approximate all information granules is *** first is the relative average approximation accuracy,which is based on all sets in the universe and has several basic *** second is the absolute average approximation accuracy,which is based on undefinable sets and has yielded significant *** also explore the relationship between these two types of average approximation ***,the average approximation accuracy has practical applications in addressing missing attribute values in incomplete information tables.
Zika virus (ZIKV) and Dengue virus (DENV) infections cause severe disease in humans and are significant socio-economic burden worldwide. These flavivirus infections are difficult to diagnose serologically due to antig...
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Zika virus (ZIKV) and Dengue virus (DENV) infections cause severe disease in humans and are significant socio-economic burden worldwide. These flavivirus infections are difficult to diagnose serologically due to antigenic overlap. The phylogenetic analysis shows that ZIKV clusters with DENVs at a higher node of the phylogenetic tree with significant genomic and structural similarity. Our study aims to identify gene biomarkers for the classification of Dengue and Zika viral infections using machine learning algorithms and bioinformatics analysis. The gene expression count matrix for single-cell RNA sequencing dataset GSE110496 was analyzed using binary classifiers, namely Logistic regression, Support Vector Machines, Random Forest, and Decision trees. The GSE110496 dataset represents a unique study of the transcriptional and translational dynamics of DENV and ZIKV infections at 4-, 12-, 24-, and 48-h time points for human hepatoma (Huh7) cells. Out of which 24-h time point has been analyzed in this study, at the optimal threshold of viral molecules. Feature selection was performed using two different approaches Random Forest Classifier (RFC) for gene ranking and Recursive Feature Elimination (RFE). Out of which RFE, showed more accuracy and precision. The classification accuracy of 89.4% and the precision of 90% were obtained using selected 10 gene features. SCY1 Like Pseudokinase 3 (SCYL3), Chromosome 1 Open Reading Frame 112 (C1orf112), Complement factor H (CFH), Heme-binding protein 1 (HEBP1), Cadherin 1 (CDH1), Nibrin (NBN), Histone deacetylase 5 (HDAC5), nuclear receptor subfamily 0, group B, member 2 (NR0B2), Annexin A9 (ANXA9) and Alcohol dehydrogenase 6 (ADH6) are the proposed gene biomarkers in this study. The functional analysis of the reported biomarkers was performed using KEGG and GO with the WEB-based Gene SeT AnaLysis Toolkit (WebGestalt). The relationship of the selected biomarkers with DENV and ZIKV infections analyzed using a gene–gene interaction n
The proposed methodology uses Artificial Neural Networks (ANN) to predict stress levels of women working in educational institutions by analyzing physiological and demographic data collected through wearable technolog...
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Polycystic Ovary Syndrome (PCOS) is a prevalent hormonal disorder affecting women during their reproductive years. It is characterized by irregular menstrual cycles, excessive hair growth, and the presence of cysts in...
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Pregnancy and fetus development is an incredibly intricate biological process that can go wrong when the health of fetus or the mother gets ***, India has the highest number of stillbirths, with an estimated 5,92,100 ...
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Proactive maintenance for the optimized lifecycle of equipment is now effortless via condition monitoring and fault diagnosis. Recognition and avoidance of a state of failure help to achieve solidity and reliability. ...
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In this technology fueled world, everyone is using smart devices, electronic gadgets, wireless products etc. and huge amounts of data are being generated, collected, and stored in the databases. To efficiently process...
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