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Publisher Correction: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly

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Nature communications 2019年第1期10卷 2459页

作者： Peer Aramillo Irizar Sascha Schäuble Daniela Esser Marco Groth Christiane Frahm Steffen Priebe Mario Baumgart Nils Hartmann Shiva Marthandan Uwe Menzel Jule Müller Silvio Schmidt Volker Ast Amke Caliebe Rainer König Michael Krawczak Michael Ristow Stefan Schuster Alessandro Cellerino Stephan Diekmann Christoph Englert Peter Hemmerich Jürgen Sühnel Reinhard Guthke Otto W Witte Matthias Platzer Eytan Ruppin Christoph Kaleta Research Group Medical Systems Biology Institute of Experimental Medicine Christian-Albrechts-University Kiel D-24105 Kiel Germany. Jena University Language and Information Engineering Lab Friedrich-Schiller-University Jena D-07743 Jena Germany. GerontoSys JenAge Consortium D-07745 Jena Germany. Genome Analysis Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Hans Berger Department of Neurology Jena University Hospital D-07747 Jena Germany. Systems Biology and Bioinformatics Group Leibniz Institute for Natural Product Research and Infection Biology-Hans-Knöll-Institute D-07745 Jena Germany. Biology of Ageing Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Molecular Genetics Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Imageing Facility Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Integrated Research and Treatment Center Center for Sepsis Control and Care (CSCC) Jena University Hospital D-07747 Jena Germany. Network Modeling Leibniz Institute for Natural Product Research and Infection Biology-Hans Knöll Institute D-07745 Jena Germany. Institute for Medical Informatics and Statistics Christian-Albrechts-University Kiel D-24105 Kiel Germany. Energy Metabolism Laboratory Swiss Federal Institute of Technology (ETH) Zurich Schwerzenbach/Zürich CH-8603 Switzerland. Department of Bioinformatics Friedrich-Schiller-University Jena D-07743 Jena Germany. Laboratory of Neurobiology Scuola Normale Superiore University of Pisa I-56100 Pisa Italy. Molecular Biology Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Faculty of Biology and Pharmacy Friedrich-Schiller-University Jena D-07743 Jena Germany. Biocomputing Lab Leibniz Institute on Aging-Fritz-Lipmann-Institute D-07745 Jena Germany. Department of Computer Science and Center for Bioinformatics and Computational Biology University of Maryland College Park M

The original version of this Article contained an error in the spelling of the author Jule Müller, which was incorrectly given as Julia Müller. Additionally, in Fig. 4a, the blue-red colour scale for fold change in ageing/disease regulation included a blue stripe in place of a red stripe at the right-hand end of the scale. These errors have been corrected in both the PDF and HTML versions of the Article.

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Synchronous oscillations in networks of time-delay coupled inert systems 4

Synchronous oscillations in networks of time-delay coupled i...

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4th IFAC Conference on Analysis and control of Chaotic Systems, CHAOS 2015

作者： Steur, E. Van Leeuwen, C. Pogromsky, A. KU Leuven Laboratory for Perceptual Dynamics Belgium Eindhoven University of Technology Institute for Complex Molecular Systems Department of Mechanical Engineering Netherlands Eindhoven University of Technology Department of Mechanical Engineering Netherlands Saint-Petersburg National Research University of Information Technologies Mechanics and Optics Department of Control Systems and Informatics Netherlands

We discuss the emergence of oscillations in networks of inert single-input-singleoutput systems which interact via linear, time-delay coupling functions. We present conditions for 1. the solutions of the time-delay coupled systems to be bounded, 2. the network equilibrium to be unique, and 3. the network equilibrium to be unstable. If these conditions are all satisfied the network of time-delay coupled inert systems has a non-trivial oscillatory solution. In addition, we show that a necessary and sufficient condition for the emerge of oscillations in such networks is that the considered systems are at least second order. Moreover, using recent results on the existence of partial synchronization manifolds, we identify the patterns of oscillation that may emerge. © 2015, IFAG (International Federation of Automatic control) Hosting by Elsevier Ltd. All rights reserved.

关键词： Time delay

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A data-driven approach to predict daily risk of Clostridium difficile infection at two large academic health centers

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Open Forum Infectious Diseases 2017年第SUPPL_1期4卷 S403-S404页

作者： Makar, Maggie Oh, Jeeheh Fusco, Christopher Marchesani, Joseph McCaffrey, Robert Rao, Krishna Ryan, Erin E Washer, Laraine West, Lauren R Young, Vincent B Guttag, John Hooper, David C Shenoy, Erica S Wiens, Jenna Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge Massachusetts Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology Cambridge Massachusetts Computer Science and Engineering University of Michigan Ann Arbor Michigan Information Systems Partners HealthCare Boston Massachusetts Department of Internal Medicine Division of Infectious Diseases University of Michigan Medical School Ann Arbor Michigan Division of Infectious Diseases Massachusetts General Hospital Boston Massachusetts Infection Control Unit Massachusetts General Hospital Boston Massachusetts Harvard Medical School Boston Massachusetts Department of Medicine Division of Infectious Diseases Massachusetts General Hospital Boston Massachusetts Medical Practice Evaluation Center Department of Medicine Massachusetts General Hospital Boston Massachusetts

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Synchronous oscillations in networks of time-delay coupled inert systems

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IFAC-PapersOnLine 2015年第18期48卷 31-36页

作者： E. Steur C. van Leeuwen A. Pogromsky KU Leuven Laboratory for Perceptual Dynamics Eindhoven University of Technology Department of Mechanical Engineering and Saint-Petersburg National Research University of Information Technologies Mechanics and Optics Department of Control Systems and Informatics Eindhoven University of Technology Institute for Complex Molecular Systems and Department of Mechanical Engineering

We discuss the emergence of oscillations in networks of inert single-input-single-output systems which interact via linear, time-delay coupling functions. We present conditions for 1. the solutions of the time-delay coupled systems to be bounded, 2. the network equilibrium to be unique, and 3. the network equilibrium to be unstable. If these conditions are all satisfied the network of time-delay coupled inert systems has a non-trivial oscillatory solution. In addition, we show that a necessary and sufficient condition for the emerge of oscillations in such networks is that the considered systems are at least second order. Moreover, using recent results on the existence of partial synchronization manifolds, we identify the patterns of oscillation that may emerge.

关键词： Coupling Instability Networks Oscillation Synchronization Time-delay

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Multi-source information fusion model in rule-based Gaussian-shaped fuzzy control inference system incorporating Gaussian density function

Multi-source information fusion model in rule-based Gaussian...

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作者： Li, Zairan He, Ting Cao, Luying Wu, Tunhua McCauley, Pamela Balas, Valentina E. Shi, Fuqian Tianjin Key Laboratory of Process Measurement and Control School of Electrical Engineering and Automation Tianjin University Tianjin China Wenzhou Vocational and Technical College Wenzhou China College of Information and Engineering Wenzhou Medical University Wenzhou325035 China Department of Industrial Engineering and Management Systems University of Central Florida OrlandoFL United States Department of Automation and Applied Informatics Aurel Vlaicu University of Arad Romania

An increasing number of applications require the integration of data from various disciplines, which leads to problems with the fusion of multi-source information. In this paper, a special information structure formalized in terms of three indices (the central presentation, population or scale, and density function) is proposed. Single and mixed Gaussian models are used for single source information and their fusion results, and a parameter estimation method is also introduced. Furthermore, fuzzy similarity computing is developed for solving the fuzzy implications under a Mamdani model and a Gaussian-shaped density function. Finally, an improved rule-based Gaussian-shaped fuzzy control inference system is proposed in combination with a nonlinear conjugate gradient and a Takagi-Sugeno (T-S) model, which demonstrated the effectiveness of the proposed method as compared to other fuzzy inference systems. © 2015 - IOS Press and the authors. All rights reserved.

关键词： Fuzzy control

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Author Correction: The challenge of mapping the human connectome based on diffusion tractography

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Nature communications 2019年第1期10卷 5059页

作者： Klaus H Maier-Hein Peter F Neher Jean-Christophe Houde Marc-Alexandre Côté Eleftherios Garyfallidis Jidan Zhong Maxime Chamberland Fang-Cheng Yeh Ying-Chia Lin Qing Ji Wilburn E Reddick John O Glass David Qixiang Chen Yuanjing Feng Chengfeng Gao Ye Wu Jieyan Ma Renjie He Qiang Li Carl-Fredrik Westin Samuel Deslauriers-Gauthier J Omar Ocegueda González Michael Paquette Samuel St-Jean Gabriel Girard François Rheault Jasmeen Sidhu Chantal M W Tax Fenghua Guo Hamed Y Mesri Szabolcs Dávid Martijn Froeling Anneriet M Heemskerk Alexander Leemans Arnaud Boré Basile Pinsard Christophe Bedetti Matthieu Desrosiers Simona Brambati Julien Doyon Alessia Sarica Roberta Vasta Antonio Cerasa Aldo Quattrone Jason Yeatman Ali R Khan Wes Hodges Simon Alexander David Romascano Muhamed Barakovic Anna Auría Oscar Esteban Alia Lemkaddem Jean-Philippe Thiran H Ertan Cetingul Benjamin L Odry Boris Mailhe Mariappan S Nadar Fabrizio Pizzagalli Gautam Prasad Julio E Villalon-Reina Justin Galvis Paul M Thompson Francisco De Santiago Requejo Pedro Luque Laguna Luis Miguel Lacerda Rachel Barrett Flavio Dell'Acqua Marco Catani Laurent Petit Emmanuel Caruyer Alessandro Daducci Tim B Dyrby Tim Holland-Letz Claus C Hilgetag Bram Stieltjes Maxime Descoteaux Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg 69120 Germany. k.maier-hein@dkfz.de. Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg 69120 Germany. Sherbrooke Connectivity Imaging Lab (SCIL) Université de Sherbrooke Sherbrooke QC J1K 0A5 QC Canada. Department of Intelligent Systems Engineering School of Informatics and Computing Indiana University Bloomington IN 47408 USA. Krembil Research Institute University Health Network Toronto Canada M5G 2C4. Department of Neurological Surgery University of Pittsburgh School of Medicine Pittsburgh PA 15213 USA. IMT-Institute for Advanced Studies Lucca 55100 Italy. Department of Diagnostic Imaging St. Jude Children's Research Hospital Memphis TN 38105 USA. University of Toronto Institute of Medical Science Toronto Canada M5S 1A8. Institute of Information Processing and Automation Zhejiang University of Technology Hangzhou 310023 Zhejiang China. United Imaging Healthcare Co Shanghai 201807 China. Shanghai Advanced Research Institute Shanghai 201210 China. Laboratory of Mathematics in Imaging Harvard Medical School Boston MA 02215 USA. Center for Research in Mathematics Guanajuato 36023 Mexico. PROVIDI Lab Image Sciences Institute University Medical Center Utrecht Utrecht 3508 The Netherlands. Cardiff University Brain Research Imaging Centre School of Psychology Cardiff University Maindy Road Cardiff CF24 4HQ UK. Department of Radiology University Medical Center Utrecht Utrecht 3508 The Netherlands. Centre de recherche institut universitaire de geriatrie de Montreal (CRIUGM) Université de Montréal Montreal QC Canada H3W 1W5. Sorbonne Universités UPMC Univ Paris 06 CNRS INSERM Laboratoire d'Imagerie Biomédicale (LIB) 75013 Paris France. Center for Advanced Research in Sleep Medicine Hôpital du Sacré-Coeur de Montréal Montreal Canada H4J 1C5. Neuroimaging Unit Institute of Bioimaging and Molecular Physiology (IBFM) Nat

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Precision Medicine:What Challenges Are We Facing?

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Genomics, Proteomics & Bioinformatics 2016年第5期14卷 253-261页

作者： Yu Xue Eric-Wubbo Lameijer Kai Ye Kunlin Zhang Suhua Chang Xiaoyue Wang Jianmin Wu Ge Gao Fangqing Zhao Jian Li Chunsheng Han Shuhua Xu Jingfa Xiao Xuerui Yang Xiaomin Ying Xuegong Zhang Wei-Hua Chen Yun Liu Zhang Zhang Kun Huang Jun Yu MOE Key Lahoratory of Molecular Biophysics College of Life Science and Technology and the Collaborative Innovation Center for Brain ScienceHuazhong University of Science and TechnologyWuhan 430074China School of Electronic and Information Engineering.Xi'an Jiaotong University.Xi'an 710049 China CAS Key Laboratory of Mental Health Institute of PsychologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of'Medical Molecular Biology Institute of Basic Medical SciencesChinese Academy of Medical SciencesPeking Union Medical CollegeBeijing 100005China MOE Beijing Key Laboratory of Carcinogenesis and Translatiooal ResearchCenter for Cancer BioinformaticsPeking University Cancer Hospital&InstituteBeijing 100142China Center for Bioinformatics State Key Laboratory of Protein and Plant Gene ResearchSchool of Life SciencesPeking UniversityBeijing 100871China Beijing Institutes of Life Science.Chinese Academy of Sciences Beijing 100101China MOE Key Lahoratory of Developnlental Genes and Human Disease Institute of Life SciencesSoutheast UniversityNanjing 210096China State Key Laboratory of Stem Cell and Reproductive Biology Institute of Zoology Chinese Academy of SciencesBeijing 100101China Max Planck Independent Research Group on Population Genomics CAS-MPG Partner Institute for Computational Biology(PICB)Shanghai Institutes for Biological SciencesChinese Academy of SciencesShanghai 200031China CAS Ker Laboratory of Genome Sciences and Information Chinese Academy of Sciences.Beijing 100101China MOE Key Laboratory of Bioinformatics School of Life Sciences Center for Synthetic and Systems BiologyTsinghua UniversityBeijing 100084China Computational Omics Lahoratory Center of Computational BiologyBeijing Institute of Basic Medical SciencesBeijing 100850China Bioinformatics Division TNLIST and MOE Key Laboratory for Bioinformatics Department of AutomationTsinghua UniversityBeijing 100084China Department of Bioinformatics and Systems Biology College of LifeScience and Technol

Following the publication of the US National Research Council （N RC） report ＂ Toward PrecMon Medicine.＂ Building a Knowledge Network for Biomedical Research and a New Taxonomy of Diseases＂ in 2011 [1], several n... 详细信息

关键词： PMI Precision Medicine data We

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25th Annual Computational Neuroscience Meeting CNS-2016, Seogwipo City, South Korea, July 2-7, 2016 Abstracts

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BMC NEUROSCIENCE 2016年第1期17卷 1-112页

作者： [Anonymous] Computational Neurobiology Laboratory The Salk Institute for Biological Studies San Diego USA UNIC CNRS Gif sur Yvette France The European Institute for Theoretical Neuroscience (EITN) Paris France ATR Computational Neuroscience Laboratories Kyoto Japan Krembil Research Institute University Health Network Toronto Canada Department of Physiology University of Toronto Toronto Canada Department of Medicine (Neurology) University of Toronto Toronto Canada Department of Physics University of New Hampshire Durham USA Department of Neurophysiology Nencki Institute of Experimental Biology Warsaw Poland Department of Theory Wigner Research Centre for Physics of the Hungarian Academy of Sciences Budapest Hungary Department of Mathematical Sciences KAIST Daejoen Republic of Korea Department of Mathematics University of Houston Houston USA Department of Biochemistry & Cell Biology and Institute of Biosciences and Bioengineering Rice University Houston USA Department of Biology and Biochemistry University of Houston Houston USA Grupo de Neurocomputación Biológica Dpto. de Ingeniería Informática Escuela Politécnica Superior Universidad Autónoma de Madrid Madrid Spain Department of Biological Sciences University of Southern California Los Angeles USA Center for Neuroscience Korea Institute of Science and Technology Seoul South Korea Department of Neurology Albert Einstein College of Medicine Bronx USA Center for Neuroscience KIST Seoul South Korea Department of Neuroscience University of Science and Technology Daejon South Korea Systems Neuroscience Group QIMR Berghofer Medical Research Institute Herston Australia Department of Psychology Yonsei University Seoul South Korea Department of Psychiatry Kyung Hee University Hospital at Gangdong Seoul South Korea Department of Psychiatry Veterans Administration Boston Healthcare System and Harvard Medical School Brockton USA Department of Electrical and Electronic Engineering The University of Melbourne Parkvil

A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Precise recruitment of spiking output at theta frequencies requires dendritic h-channels in multi-compartment models of oriens-lacunosum/moleculare hippocampal interneurons Vladislav Sekulić, Frances K. Skinner F2 Kernel methods in reconstruction of current sources from extracellular potentials for single cells and the whole brains Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári F3 The synchronized periods depend on intracellular transcriptional repression mechanisms in circadian clocks. Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić O1 Assessing irregularity and coordination of spiking-bursting rhythms in central pattern generators Irene Elices, David Arroyo, Rafael Levi, Francisco B. Rodriguez, Pablo Varona O2 Regulation of top-down processing by cortically-projecting parvalbumin positive neurons in basal forebrain Eunjin Hwang, Bowon Kim, Hio-Been Han, Tae Kim, James T. McKenna, Ritchie E. Brown, Robert W. McCarley, Jee Hyun Choi O3 Modeling auditory stream segregation, build-up and bistability James Rankin, Pamela Osborn Popp, John Rinzel O4 Strong competition between tonotopic neural ensembles explains pitch-related dynamics of auditory cortex evoked fields Alejandro Tabas, André Rupp, Emili Balaguer-Ballester O5 A simple model of retinal response to multi-electrode stimulation Matias I. Maturana, David B. Grayden, Shaun L. Cloherty, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin O6 Noise correlations in V4 area correlate with behavioral performance in visual discrimination task Veronika Koren, Timm Lochmann, Valentin Dragoi, Klaus Obermayer O7 Input-location dependent gain modulation in cerebellar nucleus neurons Maria Psarrou, Maria Schilstra, Neil Davey, Benjamin Torben-Ni

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World Congress Integrative Medicine & Health 2017: part two Berlin, Germany. 3-5 May 2017 Abstracts

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BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE 2017年第SUPPL 1期17卷 317-317页

作者： [Anonymous] National Institute of Complementary Medicine Western Sydney University Sydney Australia Department of General Practice University of Melbourne Melbourne Australia School of Rehabilitation Therapy Queens University Ontario Canada School of Health and Biomedical Sciences RMIT University Melbourne Australia School of Public Health and Preventive Medicine Monash University Melbourne Australia NAFKAM UiT The Arctic University of Norway Tromsø 9019 Norway Department of Psychology University of Sheffield Sheffield S1 1HD UK Department of Community Medicine UiT The Arctic University of Norway Tromsø 9019 Norway Institue of General Practice Goethe University Frankfurt Frankfurt 60590 Germany Department of General Practice University of Tübingen Tübingen Germany Med.-pharm. Information/Klinische Forschung WALA Heilmittel GmbH Bad Boll/ Eckwälden 73087 Germany Ressortleitung Wissenschaft WALA Heilmittel GmbH Bad Boll/Eckwälden 73087 Germany University of Minnnesota Minneapolis 55455 MN USA Minneapolis College of Art and Design Minneapolis MN USA Duke University Durham NC USA Caring Bridge Minneapolis MN USA University of Minnesota Minneapolis 55455 MN USA Phytomedicines Supply and Development Center Innovation & Development Bayer Consumer Health Steigerwald Arzneimittelwerk GmbH Darmstadt 68526 Germany University Medicine of Rostock Rostock 18055 Germany Primary Care and Population Sciences University of Southampton Southampton UK Psychology University of Southampton Southampton UK Faculty of Health University of Technology Sydney Sydney 2007 Australia st Department of Pathology and Experimental Cancer Research Semmelweis University Budapest 1085 Hungary University of Alberta Edmonton Canada Parker University Dallas TX USA Canadian Memorial Chiropractic College Toronto Canada Anglo-European College of Chiropractic Bournemouth UK University of Calgary Calgary Canada University of Toronto Toronto Canada University of Hawaii at Manoa Honolulu Hawai’

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Erratum to: Supplemental vibrotactile feedback control of stabilization and reaching actions of the arm using limb state and position error encodings

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Journal of neuroengineering and rehabilitation 2017年第1期14卷 69页

作者： Alexis R Krueger Psiche Giannoni Valay Shah Maura Casadio Robert A Scheidt Biomedical Engineering Marquette University Milwaukee WI USA. Informatics Bioengineering Robotics and Systems Engineering University of Genova Genoa Italy. Robotics Brain and Cognitive Science Italian Institute of Technology Genoa Italy. Biomedical Engineering Marquette University Milwaukee WI USA. robert.scheidt@marquette.edu. Physical Medicine and Rehabilitation Northwestern University Feinberg School of Medicine Chicago IL USA. robert.scheidt@marquette.edu. Sensory Motor Performance Program Rehabilitation Institute of Chicago Chicago IL USA. robert.scheidt@marquette.edu. Neurology Medical College of Wisconsin Wauwatosa WI USA. robert.scheidt@marquette.edu. Neuromotor Control Laboratory Department of Biomedical Engineering Marquette University Olin Engineering Center 206 P.O. Box 1881 Milwaukee WI 53201-1881 USA. robert.scheidt@marquette.edu.

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