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European control Conference (ECC)

作者： Boulaïd Boulkroune Michel Kinnaert Ali Zemouche Department of Control Engineering and System Analysis Universite Libre de Bruxelles (ULB) Roosevelt Brussels Belgium Centre de Recherche en Automatique de Nancy Nancy-Université Cosnes et Romain France

ISBN: (纸本)9781479901890

Chromatographic separation is a powerful technique based on the differential adsorption of the components of a mixture. In simulated moving bed (SMB) chromatographic processes, a counter-current movement of the liquid and the solid phases is achieved by periodically switching the inlet and the outlet ports in a closed loop of chromatographic columns. This paper addresses the problem of state observation of simulated moving bed (SMB) chromatographic processes. The proposed approach is based on a reduced model obtained via the proper orthogonal decomposition (POD) method. The state estimation is performed using a nonlinear observer designed for Lipschitz LPV (linear parameter varying) systems. Numerical simulations are provided to validate the proposed approach.

关键词： Mathematical model Observers Equations Switches Approximation methods Vectors Computational modeling

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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

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Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

关键词： Pulmonary Arterial Hypertension Oral Squamous Cell Carcinoma Deep Neural Network Autosomal Recessive Polycystic Kidney Disease Whole Genome Bisulfite Sequencing

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Optimising performance in steady state for a supermarket refrigeration system

Optimising performance in steady state for a supermarket ref...

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2012 20th Mediterranean Conference on control and Automation, MED 2012

作者： Green, Torben Kinnaert, Michel Razavi-Far, Roozbeh Izadi-Zamanabadi, Roozbeh Niemann, Henrik Danfoss A/S Refrigeration and A/C Controls 6430 Nordborg Denmark Department of Electronic Systems Aalborg University 9220 Aalborg Denmark Department of Control Engineering System Analysis at Université Libre de Bruxelles 1050 Bruxelles Belgium Department of Electrical Enigeering Technical University of Denmark 2800 Lyngby Denmark

ISBN: (纸本)9781467325318

Using a supermarket refrigeration system as an illustrative example, the paper postulates that by appropriately utilising knowledge of plant operation, the plant wide performance can be optimised based on a small set of variables. Focusing on steady state operations, the total system performance is shown to predominantly be influenced by the suction pressure. Employing appropriate performance function leads to conclusions on the choice of set-point for the suction pressure that are contrary to the existing practice. analysis of the resulting data leads to a simple method for finding optimal pressure set-point for given load situations. © 2012 IEEE.

关键词： Refrigeration

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Automatic segmentation of brain tumors in magnetic resonance images

Automatic segmentation of brain tumors in magnetic resonance...

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IEEE-EMBS International Conference on Biomedical and Health Informatics, BHI 2012. In Conj. with the 8th Int. Symp.on Medical Devices and Biosensors and the 7th Int. Symp. on Biomedical and Health engineering

作者： Behzadfar, Neda Soltanian-Zadeh, Hamid Control and Intelligent Processing Center of Excellence School of Electrical and Computer Engineering University of Tehran Tehran 14395-515 Iran Pooyandegan Rah Saadat Company Tehran 16756-965 Iran Image Analysis Laboratory Radiology Department HenryFord Healh System Detroit MI 48202 United States

ISBN: (纸本)9781457721779

Segmentation of tumors in magnetic resonance images (MRI) is an important task but is quite time consuming when performed manually by experts. Automating this process is challenging due to the high diversity in appearance of tumor tissue in different patients, and in many cases, similarity between tumor and normal tissues. This paper presents an automatic method for segmentation of brain tumors in MRI. We use images of patients with glioblastoma multiform tumors. After pre-processing and removal of the regions that do not have useful information (e.g., eyes and scalp), we create a projection image for determining the primary location of the tumor. This image provides an overall view of the tumor. Then, we grow the primary region to segment the entire tumor. This method is automatic and independent of the operator. It segments low contrast tumors without requiring their exacta tissue boundaries. The segmentation results obtained by the proposed approach are compared with those of an expert radiologist showing excellent correlations among them (R2=0.97). © 2012 IEEE.

关键词： Tumors

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Voxel-based treatment prediction of glioblastoma multiform tumor using diffusion tensor imaging

Voxel-based treatment prediction of glioblastoma multiform t...

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作者： Sabahi, Hadi Soltanian-Zadeh, Hamid Scarpace, Lisa Mikkelsen, Tom Control and Intelligent Processing Center of Excellence School of Electrical and Computer Engineering University of Tehran Tehran 14395-515 Iran Image Analysis Laboratory Radiology Department Henry Ford Hospital Detroit MI 48202 United States Hermelin Brain Tumor Research Center Neurosurgery Department Henry Ford Health System Detroit MI 48202 United States

ISBN: (纸本)9781457721779

This paper proposes a method to predict the effect of Bevacizumab therapy on Glioblastoma Multiform (GBM) tumors. The prediction is critical for effective treatment planning. The proposed method is developed and evaluated using Diffusion Tensor Imaging (DTI) and post-contrast T1-weighted Magnetic Resonance Images (pc-T1-MRI) of 14 patients with GBM tumors gathered before and after the treatment. First, the proposed method calculates diffusion anisotropy indices (DAI) of all voxels in the brain. These diffusion anisotropy indices are Fractional Anisotropy (FA), Mean Diffusivity (MD), Relative Anisotropy (RA), and Volume Ratio (VR). Then, it registers post-treatment pc-T1-MRI and pre-treatment DAI maps to pre-treatment pc-T1-MRI. Next, it uses a thresholding method to segment the tumor from pc-T1-MRI studies. Comparing Gd-enhanced voxels of the pre- and post-treatment pc-T1-MRI, the DAIs of the tumor are labeled based on their response to the treatment. The voxels of 7 patients are randomly selected to train 4 classifiers (ANN, SVM, KNN, and ANFIS) and then all voxels of the other 7 patients are used to test them. For each classifier, four performance measures (sensitivity, specificity, positive predictive value, and accuracy) are calculated. Experimental results show that the ANFIS is more accurate than the other classifiers in predicting the treatment response. © 2012 IEEE.

关键词： Tumors

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Differential energy based microgrid protection against fault conditions

Differential energy based microgrid protection against fault...

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2012 IEEE PES Innovative Smart Grid Technologies, ISGT 2012

作者： Samantaray, S.R. Joos, Geza Kamwa, I. School of Electrical Sciences Indian Institute of Technology Bhubaneswar-751013 India Department of Electrical and Computer Engineering McGill University McConnell 633 3480 University Street Montreal QC H3A 2A7 Canada Hydro-Quebec/IREQ Power System Analysis Operation and Control Varennes QC J3X 1S1 Canada

ISBN: (纸本)9781457721588

A differential energy based fault protection in microgrid is presented in this paper. Initially the currents at the respective buses are retrieved and processed through a novel time-frequency transform known as S-transform to generate time-frequency contours. Spectral energy content of the time-frequency contours of fault current signals are calculated and differential energy is computed to register the fault patterns in the microgrid at grid-connected and islanded mode. The proposed scheme is tested for different shunt faults (symmetrical and unsymmetrical) and High Impedance Faults (HIF) in the microgrid with radial and loop structure. The results based on extensive study indicate that the differential energy based protection scheme can reliably protect the microgrid against different fault situations. © 2012 IEEE.

关键词： Mathematical transformations

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Differential energy based microgrid protection against fault conditions

Differential energy based microgrid protection against fault...

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Innovative Smart Grid Technologies (ISGT)

作者： S.R. Samantaray Geza Joos I. Kamwa School of Electrical Sciences Indian Institute of Technology Bhubaneswar India Department of Electrical and Computer Engineering McGill University Montreal QUE Canada Hydro-Quebec/IREQ Power System Analysis Operation and Control Varennes QUE Canada

关键词： Time frequency analysis Fault currents Pattern recognition Impedance Wavelet transforms Mathematical model

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Hippocampal shape analysis in the Laplace Beltrami feature space for temporal lobe epilepsy diagnosis and lateralization

Hippocampal shape analysis in the Laplace Beltrami feature s...

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IEEE International Symposium on Biomedical Imaging

作者： Rosita Shishegar Ziba Gandomkar Hamid Soltaman-Zadeh Seyed Reza Moghadasi Control and Intelligent Processing Centre of Excellence (CIPCE) School of Electrical and Computer Engineering College of Engineering University of Tehran Tehran Iran Radiology Image Analysis Laboratory Henry Ford Health System Detroit MI USA Department of Mathematics Sharif University of Technology Tehran Iran

Shape analysis plays an important role in many medical imaging studies. One of the recent shape analysis methods uses the Laplace Beltrami operator which is also used in this paper for hippocampal shape comparison. We proposed a feature vector which consists of size measures and shape descriptors based on Laplace Beltrami eigenvalues and eigenfunctions. The aforementioned feature space is utilised for automatic differentiating normal subjects from epileptic patients as well as distinguishing epileptic patients with left temporal lobe epilepsy (LTLE) from patients with right temporal lobe epilepsy (RTLE). Achieved results are diagnostic accuracy of 93% with 95% sensitivity and lateralization accuracy of 86%. The results are comparable to spherical harmonic based shape analysis results and notably improved in comparison to volumetric analysis results.

关键词： Shape Temporal lobe Epilepsy Abstracts Indexes Eigenvalues and eigenfunctions Feature extraction

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Plant-wide performance optimisation - The refrigeration system case

Plant-wide performance optimisation - The refrigeration syst...

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IEEE Conference on control Technology and Applications (CCTA)

作者： Torben Green Roozbeh Razavi-Far Roozbeh Izadi-Zamanabadi Henrik Niemann Torben Green and Roozbeh Izadi-Zamanabadi are working at Danfoss A/S Refrigeration and A/C controls Nordborg Denmark postdoc at Department of Control Engineering and System Analysis at Universite Libre De Bruxelles Bruxelles Belgium Department of Electrical Enigeering at Technical University of Denmark Lyngby Denmark

This paper investigates the problem of plant-wide performance optimisation seen from an industrial perspective. The refrigeration system is used as a case study, because it has a distributed control architecture and operates in steady state conditions, which is common for many industrial applications in the process industry. The paper addresses the fact that dynamic performance of the system is important, to ensure optimal changes between different operation conditions. To enable optimisation of the dynamic controller behaviour a method for designing the required excitation signal is presented. Furthermore, invasive weed optimisation is used to find the optimal parameters for local controllers based on the plant wide performance measure.

关键词： Optimization Compressors control systems Steady-state Standards Temperature measurement Delay effects

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Interpolation of Orientation Distribution Functions (ODFs) in Q-ball Imaging

Interpolation of Orientation Distribution Functions (ODFs) i...

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Iranian Conference of Biomedical engineering

作者： Maryam Afzali Emad Fatemizadeh Hamid Soltanian-Zadeh Department of Electrical Engineering Biomedical Signal and Image Processing Laboratory(BiSIPL) Sharif University of Technology Tehran Iran Control and Intelligent Processing Center of Excellence(CIPCE) School of Electrical and Computer Engineering University of Tehran Tehran Iran & Image Analysis Laboratory Radiology Department Henry Ford Health System Detroit Michigan USA

ISBN: (纸本)9781467331289

Diffusion tensor magnetic resonance imaging (DTMRI) is a non-invasive method for investigating the brain white matter structure. It can be used to evaluate fiber bundles in the brain but in the regions with crossing fibers, it fails. To resolve this problem, high angular resolution diffusion imaging (HARDI) with a large number of diffusion encoding directions is used and for reconstruction, the Q-ball method is applied. In this method, orientation distribution function (ODF) of fibers can be calculated. Mathematical models play a crucial role in the field of ODF. For instance, in registering Q-ball images for applications like group analysis or atlas construction, one needs to interpolate ODFs. To this end, principal diffusion directions (PDDs) of each ODF are needed. In this paper, PDDs are defined as vectors that connect the corresponding local maxima of ODF values. Then, ODFs are interpolated using PDDs. The proposed method is evaluated and compared with previous protocols. Experimental results show that the proposed interpolation algorithm preserves the principal direction of fiber tracts without producing any deviations in the tracts. It is shown that changes in the entropy of the interpolated ODFs are almost linear and the bloating effect (blurring of the principal directions) can be removed.

关键词： High angular resolution diffusion imaging (HARDI) Q-ball imaging Orientation distribution function (ODF) Interpolation Principal diffusion direction (PDD)

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