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Author Correction: Drug classification with a spectral barcode obtained with a smartphone Raman spectrometer

Nature communications 2023年第1期14卷 5577页

作者： Un Jeong Kim Suyeon Lee Hyochul Kim Yeongeun Roh Seungju Han Hojung Kim Yeonsang Park Seokin Kim Myung Jin Chung Hyungbin Son Hyuck Choo Metaphotonics TU Samsung Advanced Institute of Technology Suwon Gyeonggi-do 16419 Republic of Korea. Machine Learning TU Samsung Advanced Institute of Technology Suwon Gyeonggi-do 16419 Republic of Korea. Department of Physics Chungnam National University Daejeon 34134 Korea. Institute of Quantum Systems Daejeon 34134 Korea. School of Integrative Engineering Chung-Ang University Seoul 06974 Republic of Korea. Department of Digital Health Samsung Advanced Institute of Health Science Sungkyunkwan University Seoul 06355 Korea. Department of Radiology Samsung Medical Center Sungkyunkwan University Seoul 06355 Korea. Department of Data Convergence and Future Medicine Sungkyunkwan University School of Medicine Suwon Gyeonggi-do 16419 Korea. Medical AI Research Center Research Institute for Future Medicine Samsung Medical Center Seoul 06351 Korea. Metaphotonics TU Samsung Advanced Institute of Technology Suwon Gyeonggi-do 16419 Republic of Korea. hyuck.choo@***.

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General feature selection technique supporting sex-debiasing in chronic illness algorithms validated using wearable device data

npj Women's Health

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npj Women's Health 2024年第1期2卷 1-11页

作者： Jamison H. Burks Patrick Kasl Benjamin L. Smarr Lauryn Keeler Bruce Severine Soltani Varun Viswanath Wendy Hartogensis Frederick M. Hecht Ashley E. Mason Stephan Dilchert Subhasis Dasgupta Ilkay Altintas Amarnath Gupta Shu Chien-Gene Lay Department of Bioengineering University of California San Diego San Diego CA USA Halıcıoğlu Data Science Institute University of California San Diego San Diego CA USA UC San Diego Health Department of Biomedical Informatics University of California San Diego San Diego CA USA Bioinformatics and Systems Biology University of California San Diego San Diego CA USA Department of Electrical and Computer Engineering University of California San Diego La Jolla CA USA Osher Center for Integrative Health University of California San Francisco San Francisco CA USA Department of Management Zicklin School of Business Baruch College The City University of New York New York NY USA San Diego Supercomputer Center University of California San Diego San Diego CA USA

In tasks involving human health condition data, feature selection is heavily affected by data types, the complexity of the condition manifestation, and the variability in physiological presentation. One type of variability often overlooked or oversimplified is the effect of biological sex. As females have been chronically underrepresented in clinical research, we know less about how conditions manifest in females. Innovations in wearable technology have enabled individuals to generate high temporal resolution data for extended periods of time. With millions of days of data now available, additional feature selection pipelines should be developed to systematically identify sex-dependent variability in data, along with the effects of how many per-person data are included in analysis. Here we present a set of statistical approaches as a technique for identifying sex-dependent physiological and behavioral manifestations of complex diseases starting from longitudinal data, which are evaluated on diabetes, hypertension, and their comorbidity.

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Publisher Correction: Advancing T cell-based cancer therapy with single-cell technologies

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Nature medicine 2024年第5期30卷 1505页

作者： Samantha L Bucktrout Nicholas E Banovich Lisa H Butterfield Cansu Cimen-Bozkus Josephine R Giles Zinaida Good Daniel Goodman Vanessa D Jonsson Caleb Lareau Alexander Marson Deena M Maurer Paul V Munson Mike Stubbington Sarah Taylor Abbey Cutchin Parker Institute of Cancer Immunotherapy San Francisco CA USA. sbucktrout@***. Integrated Cancer Genomics Division Translational Genomics Research Institute Phoenix AZ USA. Parker Institute of Cancer Immunotherapy San Francisco CA USA. Tisch Cancer Institute Icahn School of Medicine at Mount Sinai New York NY USA. Department of Systems Pharmacology and Translational Therapeutics University of Pennsylvania Philadelphia PA USA. Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Stanford Cancer Institute and Department of Biomedical Data Science Stanford University School of Medicine Stanford CA USA. Microbiology and Immunology School of Medicine University of California San Francisco San Francisco CA USA. Department of Applied Mathematics University of California Santa Cruz Santa Cruz CA USA. Department of Biomolecular Engineering University of California Santa Cruz Santa Cruz CA USA. Genomics Institute University of California Santa Cruz Santa Cruz CA USA. Department of Pathology Stanford University School of Medicine Stanford CA USA. Gladstone-UCSF Institute for Genomic Immunology San Francisco CA USA. 10x Genomics Pleasanton CA USA.

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Author Correction: General feature selection technique supporting sex-debiasing in chronic illness algorithms validated using wearable device data

npj Women's Health

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npj Women's Health 2024年第1期2卷 1页

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A global overview of marine heatwaves in a changing climate (vol 5, 701, 2024)

COMMUNICATIONS EARTH & ENVIRONMENT

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COMMUNICATIONS EARTH & ENVIRONMENT 2024年第1期5卷 701页

作者： Capotondi, Antonietta Rodrigues, Regina R. Sen Gupta, Alex Benthuysen, Jessica A. Deser, Clara Froelicher, Thomas L. Lovenduski, Nicole S. Amaya, Dillon J. Le Grix, Natacha Xu, Tongtong Hermes, Juliet Holbrook, Neil J. Martinez-Villalobos, Cristian Masina, Simona Roxy, Mathew Koll Schaeffer, Amandine Schlegel, Robert W. Smith, Kathryn E. Wang, Chunzai University of Colorado Boulder Cooperative Institute for Research in Environmental Sciences Boulder USA (GRID:grid.266190.a) (ISNI:***) NOAA/Physical Sciences Laboratory Boulder USA (GRID:grid.511342.0) Federal University of Santa Catarina Florianópolis Brazil (GRID:grid.411237.2) (ISNI:0000 0001 2188 7235) University of New South Wales Climate Change Research Centre and Centre for Marine Science and Innovation Sydney Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432) University of New South Wales Australian Research Council Centre of Excellence for Climate Extremes Sydney Australia (GRID:grid.1005.4) (ISNI:0000 0004 4902 0432) Australian Institute of Marine Science Crawley Australia (GRID:grid.1046.3) (ISNI:0000 0001 0328 1619) National Center for Atmospheric Research Climate and Global Dynamics Laboratory Boulder USA (GRID:grid.57828.30) (ISNI:0000 0004 0637 9680) University of Bern Climate and Environmental Physics Physics Institute Bern Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157) University of Bern Oeschger Centre for Climate Change Research Bern Switzerland (GRID:grid.5734.5) (ISNI:0000 0001 0726 5157) University of Colorado Boulder Department of Atmospheric and Oceanic Sciences and Institute of Arctic and Alpine Research Boulder USA (GRID:grid.266190.a) (ISNI:***) NOAA/Physical Sciences Laboratory Boulder USA (GRID:grid.511342.0) South African Environmental Observation Network Cape Town South Africa (GRID:grid.507758.8) (ISNI:0000 0004 0499 441X) University of Tasmania Institute for Marine and Antarctic Studies Hobart Australia (GRID:grid.1009.8) (ISNI:0000 0004 1936 826X) University of Tasmania ARC Centre of Excellence for Climate Extremes Hobart Australia (GRID:grid.1009.8) (ISNI:0000 0004 1936 826X) Universidad Adolfo Ibáñez Faculty of Engineering and Science Santiago Chile (GRID:grid.440617.0) (ISNI:0000 0001 2162 5606) ANID Technology Center No. DO210001 Data Observatory Foundation Santiago Chile (GRID:grid.440617.0) CMCC Foundation—Euro-M

Marine heatwaves have profoundly impacted marine ecosystems over large areas of the world oceans, calling for improved understanding of their dynamics and predictability. Here, we critically review the recent substantial advances in this active area of research, including the exploration of the three-dimensional structure and evolution of these extremes, their drivers, their connection with other extremes in the ocean and over land, future projections, and assessment of their predictability and current prediction skill. To make progress on predicting and projecting marine heatwaves and their impacts, a more complete mechanistic understanding of these extremes over the full ocean depth and at the relevant spatial and temporal scales is needed, together with models that can realistically capture the leading mechanisms at those scales. Sustained observing systems, as well as measuring platforms that can be rapidly deployed, are essential to achieve comprehensive event characterizations while also chronicling the evolving nature of these extremes and their impacts in our changing *** understanding of marine heatwave predictability and impacts requires analysis of these extremes at full ocean depth, using models and observations capturing their key drivers at the relevant scales, according to a broad literature review.

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Real-time prediction of COVID-19 related mortality using electronic health records

arXiv

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arXiv 2020年

作者： Schwab, Patrick Mehrjou, Arash Parbhoo, Sonali Celi, Leo Anthony Hetzel, Jürgen Hofer, Markus Schölkopf, Bernhard Bauer, Stefan F. Hoffmann-La Roche Ltd Basel Switzerland Max Planck Institute for Intelligent Systems Tübingen Germany ETH Zurich Switzerland John A. Paulson School of Engineering and Applied Sciences Harvard University Cambridge United States Department of Medicine Beth Israel Deaconess Medical Center Harvard Medical School Boston United States MIT Critical Data Laboratory for Computational Physiology Institute for Medical Engineering and Science Harvard-MIT Health Sciences & Technology Cambridge United States Department of Medical Oncology and Pneumology University Hospital of Tübingen Germany Department of Pneumology Kantonsspital Winterthur Switzerland CIFAR Azrieli Global Scholar

Coronavirus Disease 2019 (COVID-19) is an emerging respiratory disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with rapid human-to-human transmission and a high case fatality rate particularly in older patients. Due to the exponential growth of infections, many healthcare systems across the world are under pressure to care for increasing amounts of at-risk patients. Given the high number of infected patients, identifying patients with the highest mortality risk early is critical to enable effective intervention and optimal prioritisation of care. Here, we present the COVID-19 Early Warning System (CovEWS), a clinical risk scoring system for assessing COVID-19 related mortality risk. CovEWS provides continuous real-time risk scores for individual patients with clinically meaningful predictive performance up to 192 hours (8 days) in advance, and is automatically derived from patients' electronic health records (EHRs) using machine learning. We trained and evaluated CovEWS using de-identified data from a cohort of 66 430 COVID-19 positive patients seen at over 69 healthcare institutions in the United States (US), Australia, Malaysia and India amounting to an aggregated total of over 2 863 years of patient observation time. On an external test cohort of 5 005 patients, CovEWS predicts COVID-19 related mortality from 78.8% (95% confidence interval [CI]: 76.0, 84.7%) to 69.4% (95% CI: 57.6, 75.2%) specificity at a sensitivity greater than 95% between respectively 1 and 192 hours prior to observed mortality events - significantly outperforming existing generic and COVID-19 specific clinical risk scores. CovEWS could enable clinicians to intervene at an earlier stage, and may therefore help in preventing or mitigating COVID-19 related mortality. Copyright © 2020, The Authors. All rights reserved.

关键词： Coronavirus

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Improved Upper Bound on the Network Function Computing Capacity

Improved Upper Bound on the Network Function Computing Capac...

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作者： Guang, Xuan Yeung, Raymond W. Yang, Shenghao Li, Congduan School of Mathematical Sciences and LPMC Nankai University Tianjin300071 China Institute of Network Coding Chinese University of Hong Kong Hong Kong Hong Kong Department of Information Engineering Chinese University of Hong Kong Hong Kong Hong Kong School of Science and Engineering Chinese University of Hong Kong Shenzhen518172 China Shenzhen Key Laboratory of IoT Intelligent Systems and Wireless Network Technology Chinese University of Hong Kong Shenzhen518172 China Shenzhen Research Institute of Big Data Shenzhen518172 China School of Electronics and Communication Engineering Sun Yat-sen University Guangzhou510006 China

The problem of network function computation over a directed acyclic network is investigated in this paper. In such a network, a sink node desires to compute with zero error a target function, of which the inputs are generated at multiple source nodes. The edges in the network are assumed to be error-free and have limited capacity. The nodes in the network are assumed to have unbounded computing capability and be able to perform network coding. The computing rate of a network code that can compute the target function over the network is the average number of times that the target function is computed with zero error for one use of the network. In this paper, we obtain an improved upper bound on the computing capacity, which is applicable to arbitrary target functions and arbitrary network topologies. This improved upper bound not only is an enhancement of the previous upper bounds but also is the first tight upper bound on the computing capacity for computing an arithmetic sum over a certain non-tree network, which has been widely studied in the literature. We also introduce a multi-dimensional array approach that facilitates evaluation of the improved upper bound. Furthermore, we apply this bound to the problem of computing a vector-linear function over a network. With this bound, we are not only able to enhance a previous result on computing a vector-linear function over a network but also simplify the proof significantly. Finally, we prove that for computing the binary maximum function over the reverse butterfly network, our improved upper bound is not achievable. This result establishes that in general our improved upper bound is non-achievable, but whether it is asymptotically achievable or not remains open. © 1963-2012 IEEE.

关键词： Network coding

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Roadmap on Electronic Structure Codes in the Exascale Era

arXiv

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arXiv 2022年

作者： Gavini, Vikram Baroni, Stefano Blum, Volker Bowler, David R. Buccheri, Alexander Chelikowsky, James R. Das, Sambit Dawson, William Delugas, Pietro Dogan, Mehmet Draxl, Claudia Galli, Giulia Genovese, Luigi Giannozzi, Paolo Giantomassi, Matteo Gonze, Xavier Govoni, Marco Gulans, Andris Gygi, François Herbert, John M. Kokott, Sebastian Kühne, Thomas D. Liou, Kai-Hsin Miyazaki, Tsuyoshi Motamarri, Phani Nakata, Ayako Pask, John E. Plessl, Christian Ratcliff, Laura E. Richard, Ryan M. Rossi, Mariana Schade, Robert Scheffler, Matthias Schütt, Ole Suryanarayana, Phanish Torrent, Marc Truflandier, Lionel Windus, Theresa L. Xu, Qimen Yu, Victor W.-Z. Perez, Danny Department of Mechanical Engineering University of Michigan Ann ArborMI48109 United States SISSA ISAS Trieste Trieste34136 Italy IOM-CNR Trieste Trieste34136 Italy Duke University DurhamNC27708 United States London Centre for Nanotechnology LondonWC1H 0AH United Kingdom WPI-MANA National Institute for Materials Science Ibaraki305-0044 Japan Humboldt-Universität zu Berlin Berlin10117 Germany McKetta Department of Chemical Engineering University of Texas at Austin AustinTX78712 United States Center for Computational Materials Oden Institute University of Texas at Austin AustinTX78712 United States Department of Physics University of Texas at Austin AustinTX78712 United States RIKEN Center for Computational Science Hyogo Kobe650-0047 Japan Pritzker School of Molecular Engineering University of Chicago ChicagoIL60637 United States Materials Science Division Argonne National Laboratory LemontIL60439 United States Université Grenoble Alpes MEM L_Sim GrenobleF-38000 France University of Udine Udine33100 Italy IMCN Université catholique de Louvain Louvain-la-neuve Belgium University of Latvia RīgaLV-1586 Latvia University of California DavisCA95616 United States Department of Chemistry & Biochemistry The Ohio State University ColumbusOH43210 United States Berlin14195 Germany Dynamics of Condensed Matter Center for Sustainable Systems Design Chair of Theoretical Chemistry Paderborn University D-33098 Germany Paderborn Center for Parallel Computing Paderborn University D-33098 Germany Department of Computational and Data Sciences Indian Institute of Science Karnataka Bengaluru560012 India Lawrence Livermore National Laboratory LivermoreCA94550 United States Department of Computer Science Paderborn University D-33098 Germany Centre for Computational Chemistry School of Chemistry University of Bristol BristolBS8 1TS United Kingdom Ames National Laboratory AmesIA50011 United States Iowa State University AmesIA50

Electronic structure calculations have been instrumental in providing many important insights into a range of physical and chemical properties of various molecular and solid-state systems. Their importance to various fields, including materials science, chemical sciences, computational chemistry and device physics, is underscored by the large fraction of available public supercomputing resources devoted to these calculations. As we enter the exascale era, exciting new opportunities to increase simulation numbers, sizes, and accuracies present themselves. In order to realize these promises, the community of electronic structure software developers will however first have to tackle a number of challenges pertaining to the efficient use of new architectures that will rely heavily on massive parallelism and hardware accelerators. This roadmap provides a broad overview of the state-of-the-art in electronic structure calculations and of the various new directions being pursued by the community. It covers 14 electronic structure codes, presenting their current status, their development priorities over the next five years, and their plans towards tackling the challenges and leveraging the opportunities presented by the advent of exascale computing. Copyright © 2022, The Authors. All rights reserved.

关键词： Electronic structure

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Corrigendum to “Manufacturer’s selling mode choice in a platform-oriented dual channel supply chain” [Expert Syst. Appl. 198 (2022) 116842]

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Expert systems with Applications 2022年 207卷

作者： Tong-Yuan Wang Zhen-Song Chen Kannan Govindan Kwai-Sang Chin Institute of Modern Logistics Henan University Kaifeng 475004 China School of Business Henan University Kaifeng 475004 China School of Transportation and Logistics Southwest Jiaotong University Chengdu 611756 China Department of Engineering Management School of Civil Engineering Wuhan University Wuhan 430072 China School of Data Science City University of Hong Kong Hong Kong China Institute of FTZ Supply Chain Shanghai Maritime University Shanghai 201306 China Yonsei Frontier Lab Yonsei University Seoul South Korea Center for Sustainable Supply Chain Engineering Department of Technology and Innovation Danish Institute for Advanced Study University of Southern Denmark Campusvej 55 Odense M Denmark Department of Advanced Design and Systems Engineering City University of Hong Kong 83 Tat Chee Avenue Kowloon Tong Hong Kong City University of Hong Kong Shenzhen Research Institute Shenzhen China

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On the limited communication analysis and design for decentralized estimation

arXiv

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arXiv 2018年

作者： Alexandru, Andreea B. Pequito, Sérgio Jadbabaie, Ali Pappas, George J. Department of Electrical and Systems Engineering School of Engineering and Applied Science University of Pennsylvania Department of Civil and Environmental Engineering Institute for Data Systems and Society Massachusetts Institute of Technology

This paper pertains to the analysis and design of decentralized estimation schemes that make use of limited communication. Briefly, these schemes equip the sensors with scalar states that iteratively merge the measurements and the state of other sensors to be used for state estimation. Contrarily to commonly used distributed estimation schemes, the only information being exchanged are scalars, there is only one common time-scale for communication and estimation, and the retrieval of the state of the system and sensors is achieved in finite-time. We extend previous work to a more general setup and provide necessary and sufficient conditions required for the communication between the sensors that enable the use of limited communication decentralized estimation schemes. Additionally, we discuss the cases where the sensors are memoryless, and where the sensors might not have the capacity to discern the contributions of other sensors. Based on these conditions and the fact that communication channels incur a cost, we cast the problem of finding the minimum cost communication graph that enables limited communication decentralized estimation schemes as an integer programming problem. Copyright © 2018, The Authors. All rights reserved.

关键词： Integer programming

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