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Size-dependent infiltration and optical detection of nucleic acids in nanoscale pores

Size-dependent infiltration and optical detection of nucleic...

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作者： Lawrie, Jenifer L. Jiao, Yang Weiss, Sharon M. Department of Electrical Engineering and Computer Science Interdisciplinary Graduate Program in Materials Science Vanderbilt University Nashville TN 37235 United States

Experiments and complimentary simulations are presented to demonstrate the size-dependent infiltration and detection of variable length nucleic acids in porous silicon with controllable pore diameters in the range of 15-60 nm. The pore diameter must be tuned according to target molecule size in order to most effectively balance sensitivity and size-exclusion. A quantitative relationship between pore size (15-60 nm), nucleic acid length (up to ~5.3 nm), and sensor response is presented with smallermolecules detected more sensitively in smaller pores as long as the pore diameter is sufficient to enable molecular infiltration and binding in the pores. The density of probe molecules on the pore walls and subsequent hybridization efficiency for targetmolecule binding are also reported and are shown to depend strongly on the method of infiltration as well as the target molecule size.© 2010 IEEE.

关键词： Porous silicon

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A fuzzy inference system to determine the number of clones in the clonal selection algorithm

A fuzzy inference system to determine the number of clones i...

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2010 2nd World Congress on Nature and Biologically Inspired Computing, NaBIC 2010

作者： Carraro, Luiz Antonio De Castro, Leandro Nunes De Ré, Angelita Maria Computer and Informatics Faculty Graduate Program in Electrical Engineering Mackenzie University São Paulo Brazil Computer Science Department State University of West-Center Parana Guarapuava Brazil

ISBN: (纸本)9781424473762

Artificial Immune Systems (AISs) are composed of techniques inspired by immunology. The clonal selection principle ensures the organism adaptation to fight invading antigens by an immune response activated by the binding of antigens and antibodies. As an immune response can be elicited even when the binding between an antigen and an antibody is not perfect, an approximate binding might suffice, and a Fuzzy Logic mechanism might be the most appropriate mechanism to control such process. This paper presents a novel hybrid model based on concepts of Immune and Fuzzy Systems with applications to pattern recognition problems. The preliminary results obtained here suggest the proposed model is a promising pattern recognition tool. © 2010 IEEE.

关键词： Fuzzy systems

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The keyword-based and semantic-driven data matching approach for assisting structuralizing the textual clinical documents

The keyword-based and semantic-driven data matching approach...

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international Conference on Biomedical engineering and Informatics

作者： Chen, Chi-Huang Ping, Xiao-Ou Wang, Zi-Jun Hsieh, Sheau-Ling Chen, Li-Chin Tseng, Yi-Ju Hsu, Ching-Wei Lai, Feipei Department of Electrical Engineering National Taiwan University Taipei Taiwan Graduate Institute of Computer Science and Information Engineering National Taiwan University Taipei Taiwan Graduate Institute of Biomedical Electronic and Bioinformatics National Taiwan University Taipei Taiwan EECS International Graduate Program Institute/IT Center National Chiao Tung University Hsinchu Taiwan

ISBN: (纸本)9781424464968

The clinical data stored in the health information system can be categorized as two types including structuralized data and non-structuralized ones. In the paper, a data extraction system is developed to assist data retrieval from the non-structuralized textual clinical documents such as radiology reports, pathology reports, etc. The system provides keyword-based and semantic-driven data matching methodology to extract the specific information from the textual clinical documents. The matching methodology provides the capabilities to recognize the selected keywords and the related semantics in the documents. Through the extraction verification interface, clinicians can extract and verify the matched information semi-automatically. The extracted data can be filled into predefined case-oriented templates. The structuralized data can be stored back into the clinical data warehouse for further analyzing. Moreover, the case-oriented templates can support collecting corresponding extracted data for various researches. ©2010 IEEE.

关键词： Semantics

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Experimental analysis of coordination strategies to support wireless sensor networks composed by static ground sensors and UAV-carried sensors

Experimental analysis of coordination strategies to support ...

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IEEE international Symposium on Parallel and Distributed Processing With Applications

作者： De Freitas, Edison Pignaton Heimfarth, Tales Pereira, Carlos Eduardo Ferreira, Armando Morado Wagner, Flávio Rech Larsson, Tony School of Information Science Computer and Electrical Engineering Halmstad University Halmstad Sweden Institute of Informatics Federal University of Rio Grande do Sul Porto Alegre Brazil Computer Science Department Federal University of Lavras Lavras Brazil Defense Engineering Graduate Program Military Institute of Engineering Rio de Janeiro Brazil

ISBN: (纸本)9780769541907

This paper presents a comparison among different strategies to coordinate the use of heterogeneous wireless sensors aimed for area surveillance. The heterogeneity among the sensor nodes is related to their sensing and mobility capabilities. The goal of the strategies is to provide coordination among the different nodes, in order to make the wireless sensor network perform its missions with higher efficiency. Strategies combine advantages of bio-inspired and utility-based approaches to coordination. Simulations of scenarios with different characteristics were performed and the results are compared and analyzed. © 2010 IEEE.

关键词： Sensor nodes

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Photoluminescence of CdSe/ZnS quantum dots in GaN/quantum dots/GaN wafer bonded system

Photoluminescence of CdSe/ZnS quantum dots in GaN/quantum do...

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作者： Li, Y. Giles, A. Stokes, E. Optical Science and Engineering Graduate Program Department of Physics and Optical Science University of North Carolina at Charlotte 9201 University City Boulevard Charlotte NC 28223 United States Nanoscale Science Graduate Program Department of Chemistry University of North Carolina at Charlotte 9201 University City Boulevard Charlotte NC 28223 United States Department of Electrical and Computer Engineering University of North Carolina at Charlotte 9201 University City Boulevard Charlotte NC 28223 United States

ISBN: (纸本)9781607681908

Wafer bonding technology is applied to the GaN/quantum dots/GaN system, where CdSe/ZnS Quantum Dots serve as both the active layer and the binding layer. Photoluminescence is observed from quantum dots following wafer bonding at various temperatures under ultra high vacuum condition. Temperature dependences of bond strength and photoluminescence properties are characterized. Annealing at elevated temperature to form wafer bonds degrades photoluminescence intensity and slightly blue shifts the wavelength. Transmission Electron Microscopy is applied to study the physical properties of vacuum annealed QDs, in which agglomeration is observed. ©The Electrochemical Society.

关键词： Gallium nitride

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Dilatometric study of ferroelectric Rb2CdI4 monoclinic crystal grown by czochralski method

Dilatometric study of ferroelectric Rb2CdI4 monoclinic cryst...

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12th international Meeting on Ferroelectricity, IMF-12 and the 18th IEEE international Symposium on Applications of Ferroelectrics, ISAF-18

作者： Yamaguchi, T. Gotou, S. Miyoshi, T. Kasano, H. Mitsui, T. Kurihama, T. Shimizu, F. Takashige, M. Department of Electrical Engineering School of Science and Engineering Meisei University Hino-shi Tokyo 191-8506 Japan Electrical Engineering Graduate School of Science and Engineering Meisei University Hino-shi Tokyo 191-8506 Japan Department of Physics Graduate School of Science and Engineering Yamaguchi University Yamaguchi-shi Yamaguchi 753-8512 Japan Laboratory of Developmental Program Faculty of Pharmaceutical Sciences Teikyo University Sagamihara-shi Kanagawa 229-0195 Japan Department of Electronics and Information Engineering College of Engineering Chubu University Kasugai-shi Aichi 487-8501 Japan Department of Electronics and Computer Science College of Science and Engineering Iwaki Meisei University Iwaki-shi Fukushima 970-8551 Japan

Crystal growth of Rb2CdI4 was performed by Czochralski method. Transparent colourless crystals with monoclinic structure were obtained. Temperature dependence of the dielectric constant along the b-axis was measured with variation of frequency. The thermal expansions x i (i = a, b, c and a′;a′ = a + c) along the four independent axes were measured both by clip-type strain-gauge dilatometer and X-ray diffraction methods. These results show distinct anomalies associated with the ferroelectric transition at TC= 210 K. Copyright © 2010 Taylor & Francis Group, LLC.

关键词： X ray diffraction

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Annual international Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Chi-Huang Chen Sheau-Ling Hsieh Yung-Ching Weng Wen-Yung Chang Feipei Lai Department of Electrical Engineering National Taiwan University Taipei Taiwan EECS International Graduate Program Institute IT Center National Chiao Tung University Hsinchu Taiwan Department of Computer Science and Engineering National Taiwan University Taiwan Institute of Computer Science and Engineering College of Computer Science National Chiao Tung University Taiwan Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taiwan

Semantic similarity measure plays an essential role in Information Retrieval and Natural Language Processing. In this paper we propose a page-count-based semantic similarity measure and apply it in biomedical domains. Previous researches in semantic web related applications have deployed various semantic similarity measures. Despite the usefulness of the measurements in those applications, measuring semantic similarity between two terms remains a challenge task. The proposed method exploits page counts returned by the Web Search Engine. We define various similarity scores for two given terms P and Q, using the page counts for querying P, Q and P AND Q. Moreover, we propose a novel approach to compute semantic similarity using lexico-syntactic patterns with page counts. These different similarity scores are integrated adapting support vector machines, to leverage the robustness of semantic similarity measures. Experimental results on two datasets achieve correlation coefficients of 0.798 on the dataset provided by A. Hliaoutakis, 0.705 on the dataset provide by T. Pedersen with physician scores and 0.496 on the dataset provided by T. Pedersen et al. with expert scores.

关键词： Semantics Biomedical measurements Correlation Kernel Training Medical services Support vector machine classification

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Photonic crystal defects with increased surface area for improved refractive index sensing

Photonic crystal defects with increased surface area for imp...

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Conference on Lasers and Electro-Optics, CLEO 2010

作者： Kang, Christopher Christopher Phare Weiss, Sharon M. Vlasov, Yurii A. Assefa, Solomon Interdisciplinary Graduate Program in Materials Science Vanderbilt University Nashville TN 37235 United States Department of Physics and Astronomy Vanderbilt University Nashville TN 37235 United States Department of Electrical Engineering and Computer Science Vanderbilt University Tennessee 37235 United States IBM T.J. Watson Research Center Yorktown Heights NY 10536 United States

Photonic crystal cavities with tunable surface area via multiple-hole defects were investigated for increased resonance wavelength shifts upon exposure to variable-index analytes. Sensitivity was improved by 10% compa... 详细信息

ISBN: (纸本)9781557528896

关键词： Refractive index

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Photonic crystal defects with increased surface area for improved refractive index sensing

Photonic crystal defects with increased surface area for imp...

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Conference on Lasers and Electro-Optics

作者： Kang, Christopher Phare, Christopher Weiss, Sharon M. Vlasov, Yurii A. Assefa, Solomon Interdisciplinary Graduate Program in Materials Science Vanderbilt University Nashville TN 37235 United States Department of Physics and Astronomy Vanderbilt University Nashville TN 37235 United States Department of Electrical Engineering and Computer Science Vanderbilt University 37235 United States IBM. T.J. Watson Research Center Yorktown Heights NY 10536 United States

Photonic crystal cavities with tunable surface area via multiple-hole defects were investigated for increased resonance wavelength shins upon exposure to variable-index analytes. Sensitivity was improved by 10% compar... 详细信息

ISBN: (纸本)9781557528902

关键词： Surface defects

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A fuzzy inference system to determine the number of clones in the clonal selection algorithm

A fuzzy inference system to determine the number of clones i...

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World Congress on Nature & Biologically Inspired Computing (NaBIC)

作者： Luiz Antonio Carraro Leandro Nunes de Castro Angelita Maria de Ré Computer and Informatics Faculty & Graduate Program in Electrical Engineering Mackenzie University São Paulo Brazil Computer Science Department State University of West-Center Parana Guarapuava Brazil

关键词： Variable speed drives Animals

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