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作者： Wang, Gang Zamzam, Ahmed S. Giannakis, Georgios B. Sidiropoulos, Nicholas D. State Key Laboratory of Intelligent Control and Decision of Complex Systems Beijing Institute of Technology Beijing100081 China Digital Technology Center Department of Electrical and Computer Engineering University of Minnesota MinneapolisMN55455 United States Department of Electrical and Computer Engineering University of Virginia CharlottesvilleVA22904 United States

Accurately monitoring the system's operating point is central to the reliable and economic operation of an autonomous energy grid. Power system state estimation (PSSE) aims to obtain complete voltage magnitude and angle information at each bus given a number of system variables at selected buses and lines. Power flow analysis amounts to solving a set of noise-free power flow equations, and is cast as a special case of PSSE. Physical laws dictate quadratic relationships between available quantities and unknown voltages, rendering general instances of power flow and PSSE nonconvex and NP-hard. Past approaches are largely based on gradient-type iterative procedures or semidefinite relaxation (SDR). Due to nonconvexity, the solution obtained via gradient-type schemes depends on initialization, while SDR methods do not perform as desired in challenging scenarios. This paper puts forth novel feasible point pursuit (FPP)-based solvers for power flow analysis and PSSE, which iteratively seek feasible solutions for a nonconvex quadratically constrained quadratic programming reformulation of the weighted least-squares (WLS). Relative to the prior art, the developed solvers offer superior numerical performance at the cost of higher computational complexity. Furthermore, they converge to a stationary point of the WLS problem. As a baseline for comparing different estimators, the Cramér-Rao lower bound is derived for the fundamental PSSE problem in this paper. Judicious numerical tests on several IEEE benchmark systems showcase markedly improved performance of our FPP-based solvers for both power flow and PSSE tasks over popular WLS-based Gauss-Newton iterations and SDR approaches. © 1991-2012 IEEE.

关键词： State estimation

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CrowdWatcher: an open-source platform to catch the eye of the crowd

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Quality and User Experience 2019年第1期4卷 1-17页

作者： Lebreton, Pierre Hupont, Isabelle Hirth, Matthias Mäki, Toni Skodras, Evangelos Schubert, Anton Raake, Alexander Group of Networked Sensing and Control (NeSC) Zhejiang University Hangzhou China Institute of Intelligent Systems and Robotics Sorbonne University Paris France User-Centric Analysis of Multimedia Data Group Technische Universität Ilmenau Ilmenau Germany Department of Computer Science Aalto University Espoo Finland Department of Electrical and Computer Engineering University of Patras Patras Greece Audio Visual Technology Group Technische Universität Ilmenau Ilmenau Germany

This paper presents the open-source eye tracking platform CrowdWatcher. It enables researchers to measure gaze location and user engagement in a crowdsourcing context through traditional RGB webcams. The proposed platform particularly advances the field of Quality of Experience (QoE) research, as it allows the experimenter to collect remotely and with very limited effort novel information from crowds of participants, such as their commitment towards a task, attention and decision-making processes. Two different experiments are described that were conducted to demonstrate the platform’s potential. The first experiment addresses the measurement of participants’ behavior while performing a movie selection task. Results show that the platform provides complementary information to traditional self-reported data by taking gaze analysis into account. This is of particular relevance, since in a crowdsourcing context decision processes and attention are difficult to assess, and there is often limited control over the engagement of the test user with the task. A second experiment is conducted in the scenario of a multimedia QoE test. Prediction accuracy is compared to a professional infrared eye tracker. While CrowdWatcher performs less well than the professional eye tracker, it is still able to collect valuable gaze information in the far more challenging environment of crowdsourcing. As an outlook to further application domains, the usage of the platform to measure user engagement allows participants who do not pay attention to the task to be identified.

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From FAIR to CURE: Guidelines for Computational Models of Biological systems

arXiv

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arXiv 2025年

作者： Sauro, Herbert M. Agmon, Eran Blinov, Michael L. Gennari, John H. Hellerstein, Joe Heydarabadipour, Adel Hunter, Peter Jardine, Bartholomew E. May, Elebeoba Nickerson, David P. Smith, Lucian P. Bader, Gary D. Bergmann, Frank Boyle, Patrick M. Dräger, Andreas Faeder, James R. Feng, Song Freire, Juliana Fröhlich, Fabian Glazier, James A. Gorochowski, Thomas E. Helikar, Tomas Hoops, Stefan Imoukhuede, Princess Keating, Sarah M. Konig, Matthias Laubenbacher, Reinhard Loew, Leslie M. Lopez, Carlos F. Lytton, William W. McCulloch, Andrew Mendes, Pedro Myers, Chris J. Myers, Jerry G. Mulugeta, Lealem Niarakis, Anna van Niekerk, David D. Olivier, Brett G. Patrie, Alexander A. Quardokus, Ellen M. Radde, Nicole Rohwer, Johann M. Sahle, Sven Schaff, James C. Sego, T.J. Shin, Janis Snoep, Jacky L. Vadigepalli, Rajanikanth Wiley, H. Steve Waltemath, Dagmar Moraru, Ion Department of Bioengineering University of Washington SeattleWA98195-5061 United States Intelligent Systems Engineering and Biocomplexity Institute Indiana University Street BloomingtonIN47408 United States Center for Cardiovascular Biology University of Washington SeattleWA98195-5061 United States eScience Institute University of Washington SeattleWA98195-5061 United States Institute for Stem Cell and Regenerative Medicine University of Washington SeattleWA98195-5061 United States School of Biological Sciences University of Bristol 24 Tyndall Avenue BristolBS8 1TQ United Kingdom Departments of Physiology & Pharmacology Neurology Downstate Health Science University BrooklynNY11203 United States Department of Neurology Kings County Hospital BrooklynNY11203 United States NASA-John H. Glenn Research Center MS 110-3 21000 Brookpark Road ClevelandOH44135 United States Center for Cell Analysis and Modeling UConn Health 263 Farmington Avenue FarmingtonCT06030-6406 United States Amsterdam Institute for Life and Environment Vrije Universiteit Amsterdam De Boelelaan 1108 Amsterdam1081 HZ Netherlands Department of Pathology and Genomic Medicine Thomas Jefferson University 1020 Locust St PhiladelphiaPA19107 United States Biological Sciences Division Pacific Northwest National Laboratory 902 Battelle Blvd RichlandWA99354 United States Auckland Bioengineering Institute University of Auckland Auckland1010 New Zealand Center of Integrative Biology University of Toulouse III-Paul Sabatier 165 Rue Marianne Grunberg-Manago Toulouse31400 France Lifeware Group Inria Building Alan Turing 1 Rue Honoré d’Estienne d’Orves Palaiseau91120 France Multiscale Modeling Group Altos Labs Redwood CityCA94065 United States partner site Tübingen Tübingen Germany Ottfried-Müller-Str. 37 Tübingen72076 Germany 06120 Germany Department of Computer Science Center for Data Science New York University New YorkNY11201 United States Department of Bi

Guidelines for managing scientific data have been established under the FAIR principles requiring that data be Findable, Accessible, Interoperable, and Reusable. In many scientific disciplines, especially computational biology, both data and models are key to progress. For this reason, and recognizing that such models are a very special type of "data", we argue that computational models, especially mechanistic models prevalent in medicine, physiology and systems biology, deserve a complementary set of guidelines. We propose the CURE principles, emphasizing that models should be Credible, Understandable, Reproducible, and Extensible. We delve into each principle, discussing verification, validation, and uncertainty quantification for model credibility;the clarity of model descriptions and annotations for understandability;adherence to standards and open science practices for reproducibility;and the use of open standards and modular code for extensibility and reuse. We outline recommended and baseline requirements for each aspect of CURE, aiming to enhance the impact and trustworthiness of computational models, particularly in biomedical applications where credibility is paramount. Our perspective underscores the need for a more disciplined approach to modeling, aligning with emerging trends such as Digital Twins and emphasizing the importance of data and modeling standards for interoperability and reuse. Finally, we emphasize that given the non-trivial effort required to implement the guidelines, the community moves to automate as many of the guidelines as possible. © 2025, CC BY.

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Energetic electron precipitation driven by electromagnetic ion cyclotron waves from ELFIN’s low altitude perspective

arXiv

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arXiv 2022年

作者： Angelopoulos, V. Zhang, X.-J. Artemyev, A.V. Mourenas, D. Tsai, E. Wilkins, C. Runov, A. Liu, J. Turner, D.L. Li, W. Khurana, K. Wirz, R.E. Sergeev, V.A. Meng, X. Wu, J. Hartinger, M.D. Raita, T. Shen, Y. An, X. Shi, X. Bashir, M.F. Shen, X. Gan, L. Qin, M. Capannolo, L. Ma, Q. Russell, C.L. Masongsong, E.V. Caron, R. He, I. Iglesias, L. Jha, S. King, J. Kumar, S. Le, K. Mao, J. McDermott, A. Nguyen, K. Norris, A. Palla, A. Roosnovo Tam, J. Xie, E. Yap, R.C. Ye, S. Young, C. Adair, L.A. Shaffer, C. Chung, M. Cruce, P. Lawson, M. Leneman, D. Allen, M. Anderson, M. Arreola-Zamora, M. Artinger, J. Asher, J. Branchevsky, D. Cliffe, M. Colton, K. Costello, C. Depe, D. Domae, B.W. Eldin, S. Fitzgibbon, L. Flemming, A. Frederick, D.M. Gilbert, A. Hesford, B. Krieger, R. Lian, K. McKinney, E. Miller, J.P. Pedersen, C. Qu, Z. Rozario, R. Rubly, M. Seaton, R. Subramanian, A. Sundin, S.R. Tan, A. Thomlinson, D. Turner, W. Wing, G. Wong, C. Zarifian, A. Earth Planetary and Space Sciences Department Institute of Geophysics and Planetary Physics University of California Los Angeles Los AngelesCA90095 United States University of Texas at Dallas RichardsonTX75080 United States CEA DAM DIF Arpajon France Atmospheric and Oceanic Sciences Departments University of California Los AngelesCA United States Johns Hopkins University Applied Physics Laboratory LaurelMD United States Department of Astronomy Center for Space Physics Boston University BostonMA United States Mechanical and Aerospace Engineering Department Henry Samueli School of Engineering University of California Los AngelesCA90095 United States School of Mechanical Industrial Manufacturing Engineering Oregon State University CorvallisOR97331 United States University of St. Petersburg St. Petersburg Russia Jet Propulsion Laboratory California Institute of Technology PasadenaCA91109 United States Space Science Institute BoulderCO80301 United States Sodankylä Geophysical Observatory University of Oulu Sodankylä Finland Materials Science and Engineering Department Henry Samueli School of Engineering University of California Los AngelesCA90095 United States Deloitte Consulting New YorkNY10112 United States Computer Science Department Henry Samueli School of Engineering University of California Los AngelesCA90095 United States Microsoft RedmondWA98052 United States Physics and Astronomy Department University of California Los AngelesCA90095 United States Department of Astronomy and Astrophysics The University of Chicago ChicagoIL60637 United States Raybeam Inc. Mountain ViewCA94041 United States SpaceX HawthorneCA90250 United States Reliable Robotics Corporation Mountain ViewCA94043 United States Los Alamos National Laboratory Los AlamosNM87545 United States Mathematics Department University of California Los AngelesCA90095 United States Planet Labs PBC San FranciscoCA94107 United States KSAT Inc. De

We review comprehensive observations of electromagnetic ion cyclotron (EMIC) wave-driven energetic electron precipitation using data from the energetic electron detector on the Electron Losses and Fields InvestigatioN (ELFIN) mission, two polar-orbiting low-altitude spinning CubeSats, measuring 50-5000 keV electrons with good pitch-angle and energy resolution. EMIC wave-driven precipitation exhibits a distinct signature in energy-spectrograms of the precipitating-to-trapped flux ratio: peaks at >0.5 MeV which are abrupt (bursty) (lasting ∼17s, or ∆L ∼ 0.56) with significant substructure (occasionally down to sub-second timescale). We attribute the bursty nature of the precipitation to the spatial extent and structuredness of the wave field at the equator. Multiple ELFIN passes over the same MLT sector allow us to study the spatial and temporal evolution of the EMIC wave - electron interaction region. Case studies employing conjugate ground-based or equatorial observations of the EMIC waves reveal that the energy of moderate and strong precipitation at ELFIN approximately agrees with theoretical expectations for cyclotron resonant interactions in a cold plasma. Using 2 years of ELFIN data uniformly distributed in local time, we assemble a statistical database of ∼50 events of strong EMIC wave-driven precipitation. Most reside at L ∼ 5 − 7 at dusk, while a smaller subset exists at L ∼ 8 − 12 at post-midnight. The energies of the peak-precipitation ratio and of the half-peak precipitation ratio (our proxy for the minimum resonance energy) exhibit an L-shell dependence in good agreement with theoretical estimates based on prior statistical observations of EMIC wave power spectra. The precipitation ratio’s spectral shape for the most intense events has an exponential falloff away from the peak (i.e., on either side of ∼ 1.45 MeV). It too agrees well with quasi-linear diffusion theory based on prior statistics of wave spectra. It should be noted though that this diffusive

关键词： Radiation belts

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Editor-in-Chief

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IEEE Access 2024年 12卷 i-xi页

作者： Derek Abbott Sonia Aissa Anuradha Annaswamy Nirwan Ansari Jun Cai Kun-Shan Chen Yixin Chen J.-C. Chiao Ayman El-Baz Shaikh Fattah Hoay Gooi Maya Gokhale Chih-Lin Ⅰ Giuseppe Iannaccone Yumi Iwashita Bruce Jacob Abbas Jamalipour Bahram Javidi Weihua Jiang Okyay Kaynak Hulya Kirkici Germano Lambert-Torres Shengtao Li Michal Mrozowski Michele Nappi Dalma Novak Hugo Proença Yi Qian Zhihua Qu Susanto Rahardja Mehrdad Saif Ali Serpengüzel Peter H. Siegel Ashitey Trebi-Ollennu Daniela Tuninetti Ge Wang Keith A. Wear Andreas Weisshaar C. Patrick Yue Enrico Zio School of Electrical and Electronic Engineering University of Adelaide Adelaide SA Australia Institut National de la Recherche Scientifique (INRS) Québec City Canada Department of Mechanical Engineering Massachusetts Institute of Technology Cambridge MA USA Department of Electrical and Computer Engineering New Jersey Institute of Technology Newark NJ USA Concordia University Montreal Canada Guilin University of Technology Guilin China Washington University St. Louis MO USA Southern Methodist University Dallas TX USA University of Louisville/Bioengineering Department Louisville KY USA Department of Electrical and Electronic Engineering Bangladesh University of Engineering and Technology Dhaka Bangladesh Nanyang Technological University Jurong West Singapore Lawrence Livermore National Laboratory Livermore CA USA China Mobile Research Institute Beijing China University of Pisa Pisa Italy NASA-JPL California Institute of Technology Pasadena CA USA Florida Polytechnic University Lakeland FL USA The University of Sydney Sydney NSW Australia University of Connecticut Storrs CT USA Nagaoka University of Technology Nagaoka Niigata Japan Department of Electrical and Electronic Engineering Boğaziçi University Istanbul Turkey University of South Alabama Mobile AL USA Gnarus Institute Itajuba Brazil Xi’an Jiaotong University Xi’an China Gdansk University of Technology Gdansk Poland University of Salerno Fisciano Italy Octane Wireless Hanover MD USA University of Beira Interior Covilhã Portugal Department of Electrical and Computer Engineering University of NebraskaLincoln Lincoln NE USA University of Central Florida Orlando Florida USA Singapore Institute of Technology 10 Dover Dr Singapore Infocomm Technology Cluster 10 Dover Dr Singapore University of Windsor Windsor Canada Department of Physics Koç University Istanbul Turkey California Institute of Technology (CalTech) Pasadena California USA NASA-JPL Mobility and Robotics Systems S

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Common Limitations of Image Processing Metrics: A Picture Story

arXiv

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arXiv 2021年

作者： Reinke, Annika Tizabi, Minu D. Sudre, Carole H. Eisenmann, Matthias Rädsch, Tim Baumgartner, Michael Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Bankhead, Peter Benis, Arriel Blaschko, Matthew Buettner, Florian Cardoso, M. Jorge Chen, Jianxu Cheplygina, Veronika Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Engelhardt, Sandy Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hamprecht, Fred Hashimoto, Daniel A. Heckmann-Nötzel, Doreen Hirsch, Peter Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kavur, A. Emre Kenngott, Hannes Kleesiek, Jens Kleppe, Andreas Koehler, Sven Kofler, Florian Kopp-Schneider, Annette Kooi, Thijs Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moher, David Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Noyan, M. Alican Petersen, Jens Polat, Gorkem Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Rieke, Nicola Riegler, Michael A. Rivaz, Hassan Saez-Rodriguez, Julio Sánchez, Clara I. Schroeter, Julien Saha, Anindo Selver, M. Alper Sharan, Lalith Shetty, Shravya Smeden, Maarten V.A.N. Stieltjes, Bram Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben V.A.N. Varoquaux, Gaël Wiesenfarth, Manuel Yaniv, Ziv R. Jäger, Paul Maier-Hein, Lena Division of Intelligent Medical Systems and HI Helmholtz Imaging Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Intelligent Medical Systems Heidelberg Germany NCT Heidelberg DKFZ University Medical Center Heidelberg Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Division of Medical Image Computing Heidelberg Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Institute of Genetics and Cancer University of Edinburgh Edinburgh United Kingdom Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Kasteelpark Arenberg 10 - box 2441 Leuven3001 Belgium Frankfurt/Mainz DKFZ UCT Frankfurt-Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany Frankfurt Cancer Insititute Germany Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for St

While the importance of automatic image analysis is continuously increasing, recent meta-research revealed major flaws with respect to algorithm validation. Performance metrics are particularly key for meaningful, objective, and transparent performance assessment and validation of the used automatic algorithms, but relatively little attention has been given to the practical pitfalls when using specific metrics for a given image analysis task. These are typically related to (1) the disregard of inherent metric properties, such as the behaviour in the presence of class imbalance or small target structures, (2) the disregard of inherent data set properties, such as the non-independence of the test cases, and (3) the disregard of the actual biomedical domain interest that the metrics should reflect. This living dynamically document has the purpose to illustrate important limitations of performance metrics commonly applied in the field of image analysis. In this context, it focuses on biomedical image analysis problems that can be phrased as image-level classification, semantic segmentation, instance segmentation, or object detection task. The current version is based on a Delphi process on metrics conducted by an international consortium of image analysis experts from more than 60 institutions worldwide. © 2021, CC BY.

关键词： Medical imaging

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Forecasting intracranial hypertension using multi-scale waveform metrics

arXiv

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arXiv 2019年

作者： Hüser, Matthias Kündig, Adrian Karlen, Walter De Luca, Valeria Jaggi, Martin Biomedical Informatics Group Department of Computer Science ETH Zürich Universitätstrasse 6 Zürich8092 Switzerland Mobile Health Systems Lab Institute of Robotics and Intelligent Systems Department of Health Sciences and Technology ETH Zürich Zürich8008 Switzerland Department of Information Technology and Electrical Engineering ETH Zürich Zürich8092 Switzerland Machine Learning & Optimization Lab EPFL Lausanne1015 Switzerland

Objective: Acute intracranial hypertension is an important risk factor of secondary brain damage after traumatic brain injury. Hypertensive episodes are often diagnosed reactively, leading to late detection and lost time for intervention planning. A pro-active approach that predicts critical events several hours ahead of time could assist in directing attention to patients at risk. Approach: We developed a prediction framework that forecasts onsets of acute intracranial hypertension in the next 8 hours. It jointly uses cerebral auto-regulation indices, spectral energies and morphological pulse metrics to describe the neurological state of the patient. One-minute base windows were compressed by computing signal metrics, and then stored in a multi-scale history, from which physiological features were derived. Main results: Our model predicted events up to 8 hours in advance with alarm recall rates of 90% at a precision of 30.3% in the MIMIC-III waveform database, improving upon two baselines from the literature. We found that features derived from high-frequency waveforms substantially improved the prediction performance over simple statistical summaries of low-frequency time serie1s, and each of the three feature classes contributed to the performance gain. The inclusion of long-term history up to 8 hours was especially important. Significance: Our results highlight the importance of information contained in high-frequency waveforms in the neurological intensive care unit. They could motivate future studies on pre-hypertensive patterns and the design of new alarm algorithms for critical events in the injured brain. Copyright © 2019, The Authors. All rights reserved.

关键词： Morphology

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Outer-linearization-based optimization algorithm for decentralized control design in flexure-linked H-gantry

Outer-linearization-based optimization algorithm for decentr...

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2018 IEEE/ASME International Conference on Advanced intelligent Mechatronics, AIM 2018

作者： Ma, Jun Chen, Si-Lu Liang, Wenyu Li, Xiaocong Teo, Chek Sing Tay, Arthur Mamun, Abdullah Al Tan, Kok Kiong SIMTech-NUS Joint Lab. on Precision Motion Systems Department of Electrical and Computer Engineering National University of Singapore Singapore117582 Singapore Department of Electrical and Computer Engineering National Universit of Singapore Singapore117583 Singapore Mechatronics Group Singapore Institute of Manufacturing Technology Singapore138634 Singapore Zhejiang Provincial Key Laboratory of Robotics and Intelligent Manufacturing Equipment Technology Ningbo Institute of Industrial Technology Chinese Academy of Sciences Ningbo Zhejiang315121 China

ISBN: (纸本)9781538618547

The dual-drive H-gantry (DHG) is widely used for high-speed high-precision Cartesian motion control applications. Compared with the rigid-linked gantry design, the flexure-linked design is able to prevent the damage of the cross-arm because a small degree of rotation angle is allowed. Nevertheless, the flexure-linked design possibly induces the resonance of the gantry because of the chattering of control signals. To maintain the precision tracking of two carriages and minimize the chattering of control efforts, we aim to seek the most suitable flexure joints among the available ones and optimize the decentralized feedback controller parameters under parametric uncertainties. The mechatronic design problem is formulated as an H2 guaranteed cost control problem. All the stabilizing feedback controller gains are parameterized over a convex set, from here, numerical procedures are developed to obtain the global optimum by means of an outer-linearization-based optimization algorithm. Experiments are carried out and the results successfully validate the optimality and the robustness of the proposed design approach. © 2018 IEEE.

关键词： Feedback control

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Decentralized controller design in flexure-linked gantry by H2 guaranteed cost optimization approach 18

Decentralized controller design in flexure-linked gantry by ...

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18th International Conference of the European Society for Precision engineering and Nanotechnology, EUSPEN 2018

作者： Ma, Jun Chen, Si-Lu Liang, Wenyu Teo, Chek Sing Tay, Arthur Al Mamun, Abdullah Tan, Kok Kiong SIMTech-NUS Joint Lab. on Precision Motion Systems Department of Electrical and Computer Engineering National University of Singapore Singapore117582 Singapore Department of Electrical and Computer Engineering National University of Singapore Singapore117583 Singapore Agency for Science Technology and Research Singapore Institute of Manufacturing Technology Singapore138634 Singapore Zhejiang Provincial Key Laboratory of Robotics and Intelligent Manufacturing Equipment Technology Ningbo Institute of Industrial Technology Chinese Academy of Sciences Ningbo Zhejiang315201 China

ISBN: (纸本)9780995775121

Dual-drive H-gantry is widely used in many industrial processes that require high-speed and high-precision Cartesian motion. Unlike the rigid-linked gantry design, the flexure-linked design is able to prevent the damage of the cross-arm because a small degree of rotation angle is possible. However, the flexure-linked design may induce the resonant modes of the gantry because of high frequency control signals. To maintain the precision tracking of two carriages and minimize the chattering of control efforts, we aim to seek the most suitable flexure joints among the available ones while optimizing the decentralized feedback controller parameters under model uncertainties. In this way, good tracking performance is achieved without costly system re-design. In this work, we formulate the mechatronic design problem as an H2 guaranteed cost control problem. All the stabilizing feedback controller gains are parameterized over a convex set, and the global optimum is obtained by means of an outer-linearization-based algorithm. Experiments are conducted and the results successfully validate the effectiveness of the proposed design approach. © 2018 CURRAN-CONFERENCE. All rights reserved.

关键词： Convex optimization Dual-drive H-gantry Flexure Mechatronic design Optimal control Parallel mechanism

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Machine learning-based prediction of acute coronary syndrome using only the pre-hospital 12-lead electrocardiogram

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Nature Communications 2020年第1期11卷 1-10页

作者： Al-Zaiti, Salah Besomi, Lucas Bouzid, Zeineb Faramand, Ziad Frisch, Stephanie Martin-Gill, Christian Gregg, Richard Saba, Samir Callaway, Clifton Sejdić, Ervin Department of Acute & Tertiary Care Nursing University of Pittsburgh Pittsburgh PA United States Department of Emergency Medicine University of Pittsburgh Pittsburgh PA United States Division of Cardiology School of Medicine University of Pittsburgh Pittsburgh PA United States Department of Electrical and Computer Engineering University of Pittsburgh Pittsburgh PA United States University of Pittsburgh Medical Center (UPMC) Pittsburgh PA United States Advanced Algorithms Development Research Center Philips Healthcare Andover MA United States Department of Biomedical Informatics University of Pittsburgh Pittsburgh PA United States Department of Intelligent Systems University of Pittsburgh Pittsburgh PA United States

Prompt identification of acute coronary syndrome is a challenge in clinical practice. The 12-lead electrocardiogram (ECG) is readily available during initial patient evaluation, but current rule-based interpretation approaches lack sufficient accuracy. Here we report machine learning-based methods for the prediction of underlying acute myocardial ischemia in patients with chest pain. Using 554 temporal-spatial features of the 12-lead ECG, we train and test multiple classifiers on two independent prospective patient cohorts (n = 1244). While maintaining higher negative predictive value, our final fusion model achieves 52% gain in sensitivity compared to commercial interpretation software and 37% gain in sensitivity compared to experienced clinicians. Such an ultra-early, ECG-based clinical decision support tool, when combined with the judgment of trained emergency personnel, would help to improve clinical outcomes and reduce unnecessary costs in patients with chest pain. © 2020, The Author(s).

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