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Proceedings of the 38th International Conference on Neural Information Processing Systems

作者： Pedro R. A. S. Bassi Wenxuan Li Yucheng Tang Fabian Isensee Zifu Wang Jieneng Chen Yu-Cheng Chou Saikat Roy Yannick Kirchhoff Maximilian Rokuss Ziyan Huang Jin Ye Junjun He Tassilo Wald Constantin Ulrich Michael Baumgartner Klaus H. Maier-Hein Paul Jaeger Yiwen Ye Yutong Xie Jianpeng Zhang Ziyang Chen Yong Xia Zhaohu Xing Lei Zhu Yousef Sadegheih Afshin Bozorgpour Pratibha Kumari Reza Azad Dorit Merhof Pengcheng Shi Ting Ma Yuxin Du Fan Bai Tiejun Huang Bo Zhao Haonan Wang Xiaomeng Li Hanxue Gu Haoyu Dong Jichen Yang Maciej A. Mazurowski Saumya Gupta Linshan Wu Jiaxin Zhuang Hao Chen Holger Roth Daguang Xu Matthew B. Blaschko Sergio Decherchi Andrea Cavalli Alan L. Yuille Zongwei Zhou Department of Computer Science Johns Hopkins University and Department of Pharmacy and Biotechnology University of Bologna and Center for Biomolecular Nanotechnologies Istituto Italiano di Tecnologia Department of Computer Science Johns Hopkins University NVIDIA Division of Medical Image Computing German Cancer Research Center (DKFZ) and Helmholtz Imaging German Cancer Research Center (DKFZ) ESAT-PSI KU Leuven Division of Medical Image Computing German Cancer Research Center (DKFZ) and Faculty of Mathematics and Computer Science Heidelberg University Division of Medical Image Computing German Cancer Research Center (DKFZ) and Faculty of Mathematics and Computer Science Heidelberg University and HIDSS4Health - Helmholtz Information and Data Science School for Health Shanghai Jiao Tong University Shanghai Artificial Intelligence Laboratory Division of Medical Image Computing German Cancer Research Center (DKFZ) Division of Medical Image Computing German Cancer Research Center (DKFZ) and Pattern Analysis and Learning Group Department of Radiation Oncology Heidelberg University Hospital Helmholtz Imaging German Cancer Research Center (DKFZ) and Interactive Machine Learning Group (IML) DKFZ School of Computer Science and Engineering Northwestern Polytechnical University Australian Institute for Machine Learning The University of Adelaide College of Computer Science and Technology Zhejiang University Hong Kong University of Science and Technology (Guangzhou) Hong Kong University of Science and Technology (Guangzhou) and Hong Kong University of Science and Technology Faculty of Informatics and Data Science University of Regensburg Faculty of Electrical Engineering and Information Technology RWTH Aachen University Faculty of Informatics and Data Science University of Regensburg and Fraunhofer Institute for Digital Medicine MEVIS Electronic & Information Engineering School Harbin Institute of Technology (Shenzhen) Shanghai Jiao Tong University and Beijing Academy of Artificial Intelligence (BAAI) S

ISBN: (纸本)9798331314385

How can we test AI performance? This question seems trivial, but it isn't. Standard benchmarks often have problems such as in-distribution and small-size test sets, oversimplified metrics, unfair comparisons, and short-term outcome pressure. As a consequence, good performance on standard benchmarks does not guarantee success in real-world scenarios. To address these problems, we present Touchstone, a large-scale collaborative segmentation benchmark of 9 types of abdominal organs. This benchmark is based on 5,195 training CT scans from 76 hospitals around the world and 5,903 testing CT scans from 11 additional hospitals. This diverse test set enhances the statistical significance of benchmark results and rigorously evaluates AI algorithms across out-of-distribution scenarios. We invited 14 inventors of 19 AI algorithms to train their algorithms, while our team, as a third party, independently evaluated these algorithms. In addition, we also evaluated pre-existing AI frameworks—which, differing from algorithms, are more flexible and can support different algorithms—including MONAI from NVIDIA, nnU-Net from DKFZ, and numerous other open-source frameworks. We are committed to expanding this benchmark to encourage more innovation of AI algorithms for the medical domain.

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Analyzing Diversity in Healthcare LLM Research: A Scientometric Perspective

arXiv

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arXiv 2024年

作者： Restrepo, David Wu, Chenwei Vásquez-Venegas, Constanza Matos, João Gallifant, Jack Celi, Leo Anthony Bitterman, Danielle S. Nakayama, Luis Filipe Laboratory for Computational Physiology Massachusetts Institute of Technology CambridgeMA United States Departamento de Telematica Universidad del Cauca Cauca Popayán Colombia Department of Electrical Engineering and Computer Science University of Michigan Ann ArborMI United States Scientific Image Analysis Lab Faculty of Medicine Universidad de Chile RM Santiago Chile Department of Computer Science Faculty of Engineering Universidad de Concepción Biobio Concepción Chile Department of Biostatistics Harvard TH Chan School of Public Health BostonMA United States Department of Medicine Beth Israel Deaconess Medical Center BostonMA United States Artificial Intelligence in Medicine Program Mass General Brigham Harvard Medical School BostonMA United States Department of Ophthalmology São Paulo Federal University São Paulo São Paulo Brazil

The deployment of large language models (LLMs) in healthcare has demonstrated substantial potential for enhancing clinical decision-making, administrative efficiency, and patient outcomes. However, the underrepresentation of diverse groups in the development and application of these models can perpetuate biases, leading to inequitable healthcare delivery. This paper presents a comprehensive scientometric analysis of LLM research for healthcare, including data from January 1, 2021, to July 1, 2024. By analyzing metadata from PubMed and Dimensions, including author affiliations, countries, and funding sources, we assess the diversity of contributors to LLM research. Our findings highlight significant gender and geographic disparities, with a predominance of male authors and contributions primarily from high-income countries (HICs). We introduce a novel journal diversity index based on Gini diversity to measure the inclusiveness of scientific publications. Our results underscore the necessity for greater representation in order to ensure the equitable application of LLMs in healthcare. We propose actionable strategies to enhance diversity and inclusivity in artificial intelligence research, with the ultimate goal of fostering a more inclusive and equitable future in healthcare innovation. © 2024, CC BY.

关键词： Decision making

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Discrete, recurrent, and scalable patterns in human judgement underlie affective picture ratings

arXiv

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arXiv 2022年

作者： Azcona, Emanuel A. Kim, Byoung-Woo Vike, Nicole L. Bari, Sumra Lalvani, Shamal Stefanopoulos, Leandros Woodward, Sean Block, Martin Katsaggelos, Aggelos K. Breiter, Hans C. Image and Video Processing Lab Department of Electrical and Computer Engineering Northwestern University EvanstonIL United States Department of Psychiatry and Behavioral Sciences Northwestern University ChicagoIL United States Integrated Marketing Communications Northwestern University EvanstonIL United States Department of Computer Science Northwestern University EvanstonIL United States Department of Radiology Northwestern University ChicagoIL United States Laboratory of Neuroimaging and Genetics Department of Psychiatry Massachusetts General Hospital Harvard School of Medicine BostonMA United States

Operant keypress tasks, where each action has a consequence, have been analogized to the construct of "wanting" and produce lawful relationships in humans that quantify preferences for approach and avoidance behavior. It is unknown if rating tasks without an operant framework, which can be analogized to "liking", show similar lawful relationships. We studied three independent cohorts of participants (N = 501, 506, and 4,019 participants) collected by two distinct organizations, using the same 7-point Likert scale to rate negative to positive preferences for pictures from the International Affective Picture Set. Picture ratings without an operant framework produced similar value functions, limit functions, and tradeoff functions to those reported in the literature for operant keypress tasks, all with Rn goodness of fits above 0.75. These value, limit, and trade-off functions were discrete in their mathematical formulation, recurrent across all three independent cohorts, and demonstrated scaling between individual and group curves. In all three experiments, the computation of loss aversion showed 95% confidence intervals below the value of 2, arguing against a strong overweighting of losses relative to gains, as has previously been reported for keypress tasks or games of chance with calibrated uncertainty. Graphed features from the three cohorts were similar and argue that preference assessments meet three of four criteria for lawfulness, providing a simple, short, and low-cost method for the quantitative assessment of preference without forced choice decisions, games of chance, or operant keypressing. This approach can easily be implemented on any digital device with a screen (e.g., cellphones). © 2022, CC BY.

关键词： Big data

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Segmentation of infrared breast images using MultiResUnet neural networks

arXiv

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arXiv 2020年

作者： Lou, Ange Guan, Shuyue Kamona, Nada Loew, Murray Medical Imaging and Image Analysis Laboratory Department of Electrical and Computer Engineering George Washington University Medical Center WashingtonDC United States Medical Imaging and Image Analysis Laboratory Department of Biomedical Engineering George Washington University Medical Center WashingtonDC United States

Breast cancer is the second leading cause of death for women in the U.S. Early detection of breast cancer is key to higher survival rates of breast cancer patients. We are investigating infrared (IR) thermography as a noninvasive adjunct to mammography for breast cancer screening. IR imaging is radiation-free, pain-free, and non-contact. Automatic segmentation of the breast area from the acquired full-size breast IR images will help limit the area for tumor search, as well as reduce the time and effort costs of manual segmentation. Autoencoder-like convolutional and deconvolutional neural networks (C-DCNN) had been applied to automatically segment the breast area in IR images in previous studies. In this study, we applied a state-of-the-art deep-learning segmentation model, MultiResUnet, which consists of an encoder part to capture features and a decoder part for precise localization. It was used to segment the breast area by using a set of breast IR images, collected in our pilot study by imaging breast cancer patients and normal volunteers with a thermal infrared camera (N2 imager). The database we used has 450 images, acquired from 14 patients and 16 volunteers. We used a thresholding method to remove interference in the raw images and remapped them from the original 16-bit to 8-bit, and then cropped and segmented the 8-bit images manually. Experiments using leave-one-out cross-validation (LOOCV) and comparison with the ground-truth images by using Tanimoto similarity show that the average accuracy of MultiResUnet is 91.47%, which is about 2% higher than that of the autoencoder. MultiResUnet offers a better approach to segment breast IR images than our previous model. Copyright © 2020, The Authors. All rights reserved.

关键词： computer aided diagnosis

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DC-UNet: Rethinking the U-Net architecture with dual channel efficient CNN for medical images segmentation

arXiv

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arXiv 2020年

作者： Lou, Ange Guan, Shuyue Loew, Murray Medical Imaging and Image Analysis Laboratory Department of Electrical and Computer Engineering George Washington University Medical Center WashingtonDC United States Medical Imaging and Image Analysis Laboratory Department of Biomedical Engineering George Washington University Medical Center WashingtonDC United States

Recently, deep learning has become much more popular in computer vision area. The Convolution Neural Network (CNN) has brought a breakthrough in images segmentation areas, especially, for medical images. In this regard, U-Net is the predominant approach to medical image segmentation task. The U-Net not only performs well in segmenting multimodal medical images generally, but also in some tough cases of them. However, we found that the classical U-Net architecture has limitation in several aspects. Therefore, we applied modifications: 1) designed efficient CNN architecture to replace encoder and decoder, 2) applied residual module to replace skip connection between encoder and decoder to improve based on the-state-of-the-art U-Net model. Following these modifications, we designed a novel architecture--DC-UNet, as a potential successor to the U-Net architecture. We created a new effective CNN architecture and build the DC-UNet based on this CNN. We have evaluated our model on three datasets with tough cases and have obtained a relative improvement in performance of 2.90%, 1.49% and 11.42% respectively compared with classical U-Net. In addition, we used the Tanimoto similarity to replace the Jaccard similarity for gray-to-gray image comparisons. Copyright © 2020, The Authors. All rights reserved.

关键词： image segmentation

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Supervision and Source Domain Impact on Representation Learning: A Histopathology Case Study

Supervision and Source Domain Impact on Representation Learn...

引用

Annual International Conference of the IEEE engineering in Medicine and Biology Society (EMBC)

作者： Milad Sikaroudi Amir Safarpoor Benyamin Ghojogh Sobhan Shafiei Mark Crowley H.R. Tizhoosh Laboratory for Knowledge Inference in Medical Image Analysis (Kimia Lab) University of Waterloo Waterloo ON Canada Department of Electrical and Computer Engineering University of Waterloo Waterloo ON Canada

ISBN: (数字)9781728119908

ISBN: (纸本)9781728119915

As many algorithms depend on a suitable representation of data, learning unique features is considered a crucial task. Although supervised techniques using deep neural networks have boosted the performance of representation learning, the need for a large sets of labeled data limits the application of such methods. As an example, high-quality delineations of regions of interest in the field of pathology is a tedious and time-consuming task due to the large image dimensions. In this work, we explored the performance of a deep neural network and triplet loss in the area of representation learning. We investigated the notion of similarity and dissimilarity in pathology whole-slide images and compared different setups from unsupervised and semi-supervised to supervised learning in our experiments. Additionally, different approaches were tested, applying few-shot learning on two publicly available pathology image datasets. We achieved high accuracy and generalization when the learned representations were applied to two different pathology datasets.

关键词： Pathology Cancer Neural networks Data models Lung Training Support vector machines

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Local Partial Zero-Forcing Combining for Cell-Free Massive MIMO Systems

arXiv

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arXiv 2022年

作者： Zhang, Jiayi Zhang, Jing Björnson, Emil Ai, Bo The School of Electronic and Information Engineering Beijing Jiaotong University Beijing100044 China The Frontiers Science Center for Smart High-Speed Railway System Beijing Jiaotong University Beijing100044 China The Department of Electrical Engineering Linköping University Linköping Sweden The Department of Computer Science KTH Royal Institute of Technology Kista Sweden The State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong University Beijing100044 China The Frontiers Science Center for Smart High-Speed Railway System Henan Joint International Research Laboratory of Intelligent Networking and Data Analysis Zhengzhou University Zhengzhou450001 China Research Center of Networks and Communications Peng Cheng Laboratory Shenzhen China

Cell-free massive multiple-input multiple-output (MIMO) provides more uniform spectral efficiency (SE) for users (UEs) than cellular technology. The main challenge to achieve the benefits of cell-free massive MIMO is to realize signal processing in a scalable way. In this paper, we consider scalable full-pilot zero-forcing (FZF), partial FZF (PFZF), protective weak PFZF (PWPFZF), and local regularized ZF (LRZF) combining by exploiting channel statistics. We derive closed-form expressions of the uplink SE for FZF, PFZF, and PWPFZF combining with large-scale fading decoding over independent Rayleigh fading channels, taking channel estimation errors and pilot contamination into account. Moreover, we investigate the impact of the number of pilot sequences, antennas per AP, and APs on the performance. Numerical results show that LRZF provides the highest SE. However, PWPFZF is preferable when the number of pilot sequences is large and the number of antennas per AP is small. The reason is that PWPFZF has lower computational complexity and the SE expression can be computed in closed-form. Furthermore, we investigate the performance of PWPFZF combining with fractional power control and the numerical results show that it improves the performance of weak UEs and realizes uniformly good service for all UEs in a scalable fashion. Copyright © 2022, The Authors. All rights reserved.

关键词： Power control

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Reduced myelin contributes to cognitive impairment in patients with monogenic small vessel disease

引用

Alzheimer's and Dementia 2025年第5期21卷 e70127页

作者： Denecke, Jannis Dewenter, Anna Lee, Jongho Franzmeier, Nicolai Valentim, Carolina Kopczak, Anna Dichgans, Martin Pirpamer, Lukas Gesierich, Benno Duering, Marco Ewers, Michael Institute for Stroke and Dementia Research (ISD) LMU University Hospital Munich Germany Laboratory for Imaging Science and Technology Department of Electrical and Computer Engineering Seoul South Korea Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy University of Gothenburg Gothenburg Sweden Munich Cluster for Systems Neurology (SyNergy) Munich Germany German Center for Neurodegenerative Disease (DZNE) Munich Germany Medical Image Analysis Center (MIAC) and Department of Biomedical Engineering University of Basel Basel Switzerland

INTRODUCTION: Myelin is pivotal for signal transfer and thus cognition. Cerebral small vessel disease (cSVD) is primarily associated with white matter (WM) lesions and diffusion changes;however, myelin alterations and related cognitive impairments in cSVD remain unclear. METHODS: We included 64 patients with familial cSVD (i.e., cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy [CADASIL]) and 20 cognitively unimpaired individuals. χ separation applied to susceptibility weighted imaging was used to assess myelin and iron within WM hyperintensities, normal appearing WM, and two strategic fiber tracts. Diffusion-based mean diffusivity and free water were analyzed for comparisons. Cognitive impairment was assessed by the Trail Making Test. RESULTS: CADASIL patients showed reduced myelin within WM hyperintensities and its penumbra in the normal appearing WM. Myelin was moderately correlated with diffusion and iron changes and associated with slower processing speed controlled for diffusion and iron alterations. DISCUSSION: Myelin constitutes WM alterations distinct from diffusion changes and substantially contributes to explaining cognitive impairment in cSVD. Highlights: χ-negative magnetic resonance signal was reduced within white matter hyperintensities and normal appearing white matter in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, suggesting widespread myelin decreases due to cerebral small vessel disease (cSVD). χ-negative values were only moderately associated with diffusion tensor imaging derived indices including free water and mean diffusivity, suggesting that χ separation depicts distinct microstructural changes in cSVD. Alterations in χ-negative values made a unique contribution to explain processing speed impairment, even when controlled for diffusion and iron changes. © 2025 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf

关键词： cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy chi separation diffusion magnetic resonance imaging susceptibility mapping white matter hyperintensities

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MONAI: An open-source framework for deep learning in healthcare

arXiv

引用

arXiv 2022年

作者： Cardoso, M. Jorge Li, Wenqi Brown, Richard Ma, Nic Kerfoot, Eric Wang, Yiheng Murrey, Benjamin Myronenko, Andriy Zhao, Can Yang, Dong Nath, Vishwesh He, Yufan Xu, Ziyue Hatamizadeh, Ali Zhu, Wentao Liu, Yun Zheng, Mingxin Tang, Yucheng Yang, Isaac Zephyr, Michael Hashemian, Behrooz Alle, Sachidanand Darestani, Mohammad Zalbagi Budd, Charlie Modat, Marc Vercauteren, Tom Wang, Guotai Li, Yiwen Hu, Yipeng Fu, Yunguan Gorman, Benjamin Johnson, Hans Genereaux, Brad Erdal, Barbaros S. Gupta, Vikash Diaz-Pinto, Andres Dourson, Andre Maier-Hein, Lena Jaeger, Paul F. Baumgartner, Michael Kalpathy-Cramer, Jayashree Flores, Mona Kirby, Justin Cooper, Lee A.D. Roth, Holger R. Xu, Daguang Bericat, David Floca, Ralf Zhou, S. Kevin Shuaib, Haris Farahani, Keyvan Maier-Hein, Klaus H. Aylward, Stephen Dogra, Prerna Ourselin, Sebastien Feng, Andrew School of Biomedical Engineering & Imaging Sciences King’s College London London United Kingdom NVIDIA Corporation Santa Clara and Bethesda United States School of Electrical and Computer Engineering Rice University Houston United States Department of Engineering Science University of Oxford Oxford United Kingdom Department of Medical Physics and Biomedical Engineering University College London London United Kingdom Department of BioAI InstaDeep Ltd London United Kingdom Department of Electrical & Computer Engineering University of Iowa Iowa City United States Mayo Clinic Jacksonville United States Mars Incorporated United States Div. Intelligent Medical Systems German Cancer Research Center Heidelberg Germany Division of Medical Image Computing German Cancer Research Center Heidelberg Germany Pattern Analysis and Learning Group Department of Radiation Oncology Heidelberg University Hospital Heidelberg Germany School of Biomedical Engineering Suzhou Institute for Advanced Research University of Science and Technology of China Suzhou China Department of Medical Physics Guy’s & St Thomas’ NHS Foundation Trust London United Kingdom National Cancer Institute Bethesda United States Kitware Inc. Clifton Park United States Department of Ophthalmology University of Colorado Aurora United States Frederick National Laboratory for Cancer Research Frederick United States Department of Pathology Northwestern University Chicago United States

Artificial Intelligence (AI) is having a tremendous impact across most areas of science. Applications of AI in healthcare have the potential to improve our ability to detect, diagnose, prognose, and intervene on human disease. For AI models to be used clinically, they need to be made safe, reproducible and robust, and the underlying software framework must be aware of the particularities (e.g. geometry, physiology, physics) of medical data being processed. This work introduces MONAI, a freely available, community-supported, and consortium-led PyTorch-based framework for deep learning in healthcare. MONAI extends PyTorch to support medical data, with a particular focus on imaging, and provide purpose-specific AI model architectures, transformations and utilities that streamline the development and deployment of medical AI models. MONAI follows best practices for software-development, providing an easy-to-use, robust, well-documented, and well-tested software framework. MONAI preserves the simple, additive, and compositional approach of its underlying PyTorch libraries. MONAI is being used by and receiving contributions from research, clinical and industrial teams from around the world, who are pursuing applications spanning nearly every aspect of healthcare. © 2022, CC BY.

关键词： Clinical research

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Understanding metric-related pitfalls in image analysis validation

arXiv

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arXiv 2023年

作者： Reinke, Annika Tizabi, Minu D. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Kavur, A. Emre Rädsch, Tim Sudre, Carole H. Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Buettner, Florian Cardoso, M. Jorge Cheplygina, Veronika Chen, Jianxu Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kleesiek, Jens Kofler, Florian Kooi, Thijs Kopp-Schneider, Annette Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Riegler, Michael A. Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. van Calster, Ben Varoquaux, Gaël Yaniv, Ziv R. Jäger, Paul F. Maier-Hein, Lena Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany NCT Heidelberg A Partnership Between DKFZ University Medical Center Heidelberg Germany Heidelberg Division of Medical Image Computing Germany Heidelberg Division of Intelligent Medical Systems Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montreal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Leuven Belgium partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany and Frankfurt Cancer Insititute Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for Statistics in Medicine University of Oxford Oxford United Kingdom Center for Biomedical In

Validation metrics are key for tracking scientific progress and bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image analysis, metrics are often chosen inadequately. While taking into account the individual strengths, weaknesses, and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multi-stage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides the first reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. While focused on biomedical image analysis, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. The work serves to enhance global comprehension of a key topic in image analysis validation. © 2023, CC BY.

关键词： computer vision

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