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7th IEEE International Conference on Bioinformatics and Bioengineering, BIBE

作者： Alterovitz, Gil Lyashenko, Eugenia Xiang, Michael Ramoni, Marco F. Division of Health Sciences and Technology Harvard Medical School Massachusetts Institute of Technology Boston MA United States Children's Hospital Informatics Program at Health Sciences and Technology Harvard Medical School Boston MA United States Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge MA United States Harvard Partners Center for Genetics and Genomics Harvard Medical School Boston MA United States Department of Biomedical Informatics Columbia University New York NY United States

ISBN: (纸本)1424415098

With the human genome sequenced, attention has been shifting to proteins and their function. Several technologies including mass spectrometry and gel electrophoresis have traditionally been used to study proteins. These technologies rely on proteins' masses to characterize and/or identify them. Once identified, the discovered proteins' are often analyzed for their functional relevance. In this paper, we present an alternative approach to studying protein function directly, based on protein mass. By analyzing proteins with similar mass ranges (bins), we discovered that certain biological functions are associated with specific mass bins more frequently than would be expected by chance. Biological functional classes found in this manner could be seen across the three examined organisms: human, worm and fly. We found no sequence-based homology across significant mass-function proteins in the three different organisms. This investigation leads to useful property that the mass-based biological functional classes are preserved across the organisms. Thus, this paper describes a potential constraint for evolution of similar function based on mass constraints. Finally, this work yields a roadmap for experimental design for functional exploration of proteomes in mass-based technologies such as gel electrophoresis and mass spectrometry. ©2007 IEEE.

关键词： Proteins

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Analysis of P-type Poly-Si TFT Degradation under Dynamic Gate Voltage Stress Using the Slicing Model

Analysis of P-type Poly-Si TFT Degradation under Dynamic Gat...

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2007亚洲显示国际会议

作者： Shih-Che Huang Hung-Chuan Tsao Ya-Hsiang Tai Department of Photonics ＆ Institute of Electro-Optical Engineering NCTU HsinchuTaiwanChina 30010 College of Electrical and Computer Engineering Industrial Technology R ＆ D Master Program on Photonics and Display Technologies NCTUHsinchuTaiwanChina 30010 Department of Photonics ＆ Display Institute NCTU HsinchuTaiwanChina 30010

＜正＞In this work,the mobility degradation after gate AC stress in the off region are *** is discovered that the mob- ility increases after AC gate stress condition 0 V to+15 V,which the previously reported model （by Uraoka.Y） may not *** the spatial distribution of the voltage and the flow of the carriers in the channel,we proposed the “slicing model”,that is,replace the original TFT by ten TFTs with shorter channel ***,by applying the circuit simulator,the voltage distribution in the channel under different stages of gate applied voltage may be *** index considering the current flow and the channel voltage at the edge nodes are proposed to describe the degradation in mobili- *** fair linearity between the proposed index and the degradation in mobility reveals the validity of the proposed model.

关键词： Reliability AC Stress Poly-Si TFT

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Separating composite signals in multi-probe dynamic biomedical imaging

Separating composite signals in multi-probe dynamic biomedic...

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Asilomar Conference on Signals, Systems & computers

作者： Li Chen Yue Wang Chong-Yung Chi Zsolt Szabo Peter L. Choyke Department of Electrical and Computer Engineering Virginia Polytechnic Institute and State University Arlington VA USA Institute of Communications Engineering National Tsing Hua University Hsinchu Taiwan Department of Radiology Johns Hopkins Medical Institutions Baltimore MD USA Molecular Imaging Program National Cancer Institute Bethesda MD USA

Multi-probe dynamic biomedical imaging promises powerful tools for the visualization and elucidation of complex biological processes. Recent research aims to simultaneously dissect the spatial-temporal distributions of source signals that often represent a composite of multiple biomarkers independent of spatial resolution. We report a hybrid unmixing method for separating non-negative dependent imaging biomarker mixtures. The geodesic-principled algorithm exploits partial-volume modeling, non-negative clustered component analysis, and convex pyramid analysis, aided by a spatial-temporal coordinated information visualization aid. We demonstrate the principle of the approach on dynamic contrast-enhanced magnetic resonance imaging data and observed the expected vascular permeability and perfusion patterns due to tumor-induced angiogenesis and responses to therapy.

关键词： Biomedical imaging Biomarkers Magnetic resonance imaging Independent component analysis Information analysis Magnetic analysis Algorithm design and analysis Visualization Biological processes Spatial resolution

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Work in progress - evaluation of the University of Maine GK-12 sensors! program

Work in progress - evaluation of the University of Maine GK-...

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Frontiers in Education (FIE) Conference

作者： Brian E. Doore Joseph Arsenault Constance Holden Stephen Godsoe John Vetelino Program Evaluator Center for Research and Evaluation University of Maine Orono ME USA Department of English University of Maine Orono ME USA Department of Spatial Engineering and Information Science University of Maine Orono ME USA Bangor High School Bangor ME USA Department of Electrical and Computer Engineering University of Maine Orono ME USA

Findings from several years of participant feedback about the NSF sponsored GK-12 Sensors! program at the University of Maine are described. The program places graduate Fellows in local K-12 classrooms, with the goal of encouraging students to consider science, technology, engineering, and mathematics professions. Three broad themes are discussed: communication, preparation, and "fit." These factors determine the success of GK-12 Fellow placements, as shown by student and teacher evaluations, Fellow satisfaction, and classroom evaluations. Successful placements strengthen program implementation and status in participating schools while marginal placements can negatively affect both teachers and students and erode support for the GK-12 initiative.

关键词： Feedback Educational institutions engineering profession Mathematics Design methodology Protocols Information science

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功率分流混合电动车辆模型的演算和实验论证

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传动技术 2007年第4期21卷 32-45页

作者： Fazal U. Syed Ming L. Kuang John Czubay Hao Ying 谷雨(译) Department of Electrical and Computer Engineering Wayne State University Detroit MI 48202 USA the Hybrid Vehicle Program Sustainable Mobility Technologies Laboratory II Ford Motor Company Dearborn MI 48120 USA the Department of Electrical and Computer Engineering Wayne State University Detroit MI 48202 USA 不详

由于环保和效率等原因混合电动车辆(HEVS)已经具有很大的吸引力。一个典型的HEV由两个动力系统:一个是普通的动力源如一台汽油机、一台柴油机或一组燃料电池和一个电动系统(包含一台电动机和一台发电机)组成,它可能产生比普通车辆高的... 详细信息

由于环保和效率等原因混合电动车辆(HEVS)已经具有很大的吸引力。一个典型的HEV由两个动力系统:一个是普通的动力源如一台汽油机、一台柴油机或一组燃料电池和一个电动系统(包含一台电动机和一台发电机)组成,它可能产生比普通车辆高的燃油经济性。而且,这样的车辆不需要外部充电,而在其内部存在燃料基本设施。HEV的功率分流动力系统构造的独特的HEV动力系统结构串联和并联型式的优点。但是操纵功率分流HEV动力系统要求一个完善的控制系统。设计这样的控制系统要有适当精确的HEV装置的平面模型。对于串联和并联型式的大量研究已经开发了许多动力平面模型。但一个完整的和有效的功率分流HEV动力系统的动力模型尚处于初期阶段。本文提出了在不同传动条件下可实际地和重复所有静态和瞬态现象的功率分流动力系统HEV的动力模型。首次表明了数学推导和这种平面模型和构件的表达,其次是通过计算机仿真分析、验证及性能鉴定和试验车辆在Ford公司性能道路试验实测进行比较。该模拟和实验结果的极好的吻合证实所引导的平面模型的精确性和正确性。因为该平面模型是综合用型谱方法论的系统定向子系统建立的,它很容易改变子系统的功率。开发该平面模型是用来分析和了解动力系的控制动力学,子系统和构件间的干扰以及由于工况和波动的影响的变化的系统瞬变。该平面模型也可用于车辆系统控制器的开发,能量管理战略的估价,结果的解析,编码算法的证明,及其中其他许多目的。

关键词：混合电动车辆功率分流车辆模型实验动力系统平面模型计算机仿真分析演算

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MODELING AND CONTROL OF ELEVATORS BY STATECHARTS

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Asian Journal of Control 2008年第2期6卷

作者： Yi-Sheng Huang Sheng-Luen Chung Mu-Der Jeng Department of Aeronautical Engineering Chung Cheng Institute of Technology National Defense University Tashi Taoyuan 335 Taiwan R.O.C. Department of Electrical Engineering National Taiwan University of Science and Technology Taipei 106 Taiwan R.O.C. Department of Electrical Engineering National Taiwan Ocean University Kellung 202 Taiwan R.O.C. MuDer Jeng received the Ph.D. degree in computer and systems engineering from Rensselaer Polytechnic Institute Troy NY in 1992. Since August 1992 Dr. Jeng has been with National Taiwan Ocean University Keelung Taiwan where he is currently a full Professor at the Department of Electrical Engineering. His current research interests include Petri nets discrete event systems computer integrated manufacturing semiconductor factory automation embedded systems. Dr. Jeng is the author/co-author of over 120 book chapters journal papers and conference papers. Dr. Jeng received the Franklin V. Taylor Outstanding Paper Award from the IEEE Systems Man and Cybernetics Society in 1993. He was granted the Research Award by the National Science Council of Taiwan annually from 1994 to 2000. He is an Associate Editor for IEEE Transactions on Systems Man and Cybernetics-Part A IEEE Transactions on Robotics and Automation IEEE Transactions on Robotics and serves on the Editorial Board of International Journal of Computer Integrated Manufacturing. He has been a Guest Editor for eight leading journals. Dr. Jeng is the Chair of the Technical Committee on Discrete Event Systems of the IEEE SMC Society and the Founding Chair of the Technical Committee on Semiconductor Factory Automation of the IEEE Robotics and Automation Society. He served as the Exhibitions Chair of 2003 IEEE International Conference on Robotics and Automation and the Special Sessions Chair of 2004 IEEE International Conference on Networking Sensing and Control. He serves as a Program Co-Chair of 2005 IEEE International Conference on Networking Sensing and Control and the Organization Commit

Statechart has been utilized as a visual formalism for the modeling of complex and interactive systems for its illuminating features on describing properties of causality, concurrency, and synchronization. This paper presents the application of satechart to the modeling, design and implementation of an elevator system, whose system behavior involves aggregating complexity of state descriptions, and imposition of underlying control policy. Based on the operational flow of an elevator, we derive the associated statechart model by looking into the inherent hierarchical structure of the elevator. The advantage of the proposed approach is the clear presentation of system behavior in terms of conditions and events that cause the transitions in system dynamics. Implementation of the controlled elevator based on the modeled statechart is also presented.

关键词： Statechart interactive systems elevator

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Oscillator models and collective motion

IEEE Control Systems Magazine

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IEEE Control Systems Magazine 2007年第4期27卷 89-105页

作者： Paley, Derek A. Leonard, Naomi Ehrich Sepulchre, Rodolphe Grünbaum, Daniel Parrish, Julia K. Princeton University Department of Mechanical and Aerospace Engineering Princeton NJ 08544 United States Department of Mechanical and Aerospace Engineering Program in Applied and Computational Mathematics Princeton University Princeton NJ 08544 United States Department Electrical Engineering and Computer Science University of Liège Liège Belgium School of Oceanography Department of Biology University of Washington Seattle WA United States Biology Department School of Aquatic and Fishery Sciences University of Washington Seattle WA United States

A description of the so called "particles with coupled oscillator dynamics" (PCOD) is presented which is used to model, analyze and synthesize collective motion. An oscillator model with spatial dynamics is presented to help describe how to design steering control laws while it is being used to study biological collectives. Lastly, both engineering and biological analysis were described.

关键词： Oscillators (mechanical)

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Molecular dynamic simulation of heat pulse propagation in multiwall carbon nanotubes

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Physical Review B 2007年第15期76卷 155424-155424页

作者： Taejin Kim Mohamed A. Osman Cecilia D. Richards David F. Bahr Robert F. Richard Material Science Program Washington State University Pullman Washington 99164-4620 USA Department of Physics Washington State University Pullman Washington 99164-2814 USA School of Electrical Engineering and Computer Science Washington State University Pullman Washington 99164-2752 USA School of Mechanical and Materials Engineering Washington State University Pullman Washington 99164-2920 USA

The propagation of heat pulses in zigzag and armchair double wall nanotubes (DWNTs) has been investigated using molecular dynamics simulations. It is found that the leading heat wave packets in zigzag (9,0)∕(18,0) and armchair (5,5)∕(10,10) DWNTs move with the speed of longitudinal acoustic (LA) phonon modes. The intensities of the leading heat wave packets in outer and inner shells in DWNTs were found to be five to seven times larger than that of the corresponding single wall nanotubes (SWNTs). The heat energy carried by the leading heat wave packets in zigzag DWNT was about four and five times more than those in armchair DWNT shells. Within the leading LA wave packet, the strain in the inner shell of the DWNTs is stronger than the strain in the outer shell and considerably larger than strain in the corresponding SWNTs. The regions with the largest strain coincide with the regions of high kinetic temperatures within the LA mode wave packets. The higher energy of the LA mode waves in DWNT shells compared to SWNT is attributed to the presence of higher strain fields in DWNTs compared to individual SWNTs. The higher strain in the inner shell of DWNT compared to the outer shell accounts for the three to five times higher kinetic energy of leading wave packets in inner shells compared to those in outer shells. The induced strain fields in zigzag DWNT are distributed over a wider region compared to armchair DWNT, and the strains in inner and outer shells of zigzag DWNT are out phase by 180°.

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Enabling a strong U.S. engineering workforce for technological innovation: A national partnership in graduate professional education with industry to enhance U.S. competitiveness and economic development

Enabling a strong U.S. engineering workforce for technologic...

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114th Annual ASEE Conference and Exposition, 2007

作者： Keating, Donald Stanford, Thomas Bardo, John Dunlap, Duane DeLoatch, Eugene Tricamo, Stephen Deoew, Dennis Bertoline, Gary Schuver, Mark McHenry, Albert Lindquist, Timothy Tidwell, Joseph Palmer, Harvey Smith, Mark Morrison, Raymond Egbert, Norm Quick, David Olson, Roger Truesdale, Samuel Noori, Mohamad Sullivan, Edward Rencis, Joseph Purdy, Carla University of South Carolina United States Department of Mechanical Engineering University of South Carolina United States ASEE-Graduate Studies Division Department of Chemical Engineering University of South Carolina United States Western Carolina University United States Kimmel School Western Carolina University United States Morgan State University United States School of Engineering Morgan State University United States ASEE New Jersey Institute of Technology United States Department of Industrial and Manufacturing Engineering Purdue University United States College of Technology Purdue University United States Rolls-Royce-Purdue Master's Degree Program Purdue University United States Arizona State University United States Arizona State University Polytechnic United States Boeing Co. United States JACMET Arizona State University Polytechnic United States ASEE-College Industry Partnership Division Rochester Institute of Technology United States Kate Gleason College of Engineering Rochester Institute of Technology United States Lockheed Martin Aeronautics Co. United States Engineering Integration and Strategy Lockheed Martin Aeronautics Company United States ASEE-Corporate Rolls-Royce Corporation United States Rolls-Royce North American Technologies United States California State Polytechnic University United States College of Engineering California State Polytechnic University United States Graduate Programs and Research College of Engineering California State Polytechnic University United States University of Arkansas United States Department of Mechanical Engineering University of Arkansas Fayetteville United States ASEE-Mechanical Engineering Division ASME Mechanical Engineering Department University of Cincinnati United States Department of Electrical and Computer Engineering University of Cincinnati United States

No abstract available

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功率分流混合电动车辆模型的演算和实验论证

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传动技术 2007年第3期21卷 30-34,26页

作者： Fazal U. Syed Ming L. Kuang John Czubay HAO Ying Department of Electrical and Computer Engineering Wayne State University Detroit MI 48202 USA the Hybrid Vehicle Program Sustainable Mobility Technologies Laboratory Ⅱ Ford Motor Compa ny Dearborn M1 48120 USA.

关键词：电动无级变速器(e-CVT) 推导混合电动车辆( HEV) 模型功率分流仿真论证

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