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Plasmonics in Biology and Medicine XXI 2024

作者： Zu, Di Li, Borui Lee, Somin Eunice Department of Electrical & Computer Engineering Biomedical Engineering Applied Physics Biointerfaces Institute Macromolecular Science & Engineering University of Michigan Ann ArborMI United States

ISBN: (纸本)9781510669796

CRISPR-Cas9 is significantly potential and versatile gene-editing treatment for neurodegenerative disorders. The CRISPR-Cas9 system incorporates a single guide RNA (sgRNA) and Cas9 nuclease, which helps system to bind to the target sequence, and makes a double-strand break respectively. Viral vectors, as traditional delivery system of CRISPRCas9, cause safety issue regrading immunogenic complications. In this work we present alternative non-viral vectors with plasmonic properties as a delivery system. Our work provides a new perspective of nanoparticles for delivery and visualization applications of the CRISPR-Cas9 system. © 2024 SPIE.

关键词： Neurodegenerative diseases

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Interferometric phase-intensity nanoscopy 21

Interferometric phase-intensity nanoscopy

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Plasmonics in Biology and Medicine XXI 2024

作者： Kim, Do Young Cui, Guangjie Lee, Somin Eunice Department of Electrical & Computer Engineering Biomedical Engineering Applied Physics Biointerfaces Institute Macromolecular Science & Engineering University of Michigan Ann ArborMI United States

ISBN: (纸本)9781510669796

We present a novel approach, interferometric phase intensity nanoscopy, to clearly define nanometer-scale objects situated closely together, going beyond the traditional diffraction limits. Our approach capitalizes on the strengths of interferometric scattering, which we've found remarkably effective for detecting entities as minute as individual nanoparticles and proteins. We integrated multiphase analysis with enhanced sensitivity to reveal elliptical Airy patterns that directly correlate with the nanostructures we observe. A key aspect of our methodology is the use of circular polarized illumination, which is essential for differentiating nanometer-scale objects that are closely spaced and below the diffraction limit. This technique opens up new possibilities for prolonged observation of nanoscale dynamics in biology, biomedicine, and bioengineering. © 2024 SPIE.

关键词： Diffraction

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Sub-10 nm nanoscopic imaging reveals sub-10nm cellular architectures 21

Sub-10 nm nanoscopic imaging reveals sub-10nm cellular archi...

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Plasmonics in Biology and Medicine XXI 2024

作者： Cui, Guangjie Kim, Do Young Zu, Di Chai, Guanbo Lee, Somin Eunice Department of Electrical & Computer Engineering Biomedical Engineering Applied Physics Biointerfaces Institute Macromolecular Science & Engineering University of Michigan Ann ArborMI United States

ISBN: (纸本)9781510669796

Phase intensity nanoscope (PINE) is a new super-resolution method to further improve the resolution of existing techniques. PINE utilizes an integrated phase-intensity device to modulate phase differences between electric field components to distinguish nanoprobes within a diffraction-limited region. This phase-intensity separation enables continuous imaging without photobleaching. PINE achieved sub-10nm resolution of cellular structures through precise localization of populations of randomly distributed nanorod probes. The distribution of localized nanorods forms patterns of underlying structures. By defining features from probe distribution patterns and minimizing the distances of each probe to its feature projection, PINE extracts sub-10nm structural information. PINE will pave the way for new sub-10nm long-term investigations of previously unexplored material, chemical and biological dynamics. © 2024 SPIE.

关键词： Probes

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Impact of Time Resolution and Window Length on the Capture of Frequency Variations and Events

Impact of Time Resolution and Window Length on the Capture o...

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2024 IEEE PES Innovative Smart Grid Technologies Europe Conference, ISGT EUROPE 2024

作者： Polajžer, Boštjan Mohammadi, Younes Saremi, Amin University of Maribor Faculty of Electrical Engineering and Computer Science Maribor Slovenia Umeå University Department of Applied Physics and Electronics Umeå Sweden

ISBN: (纸本)9789531842976

Power-quality standards provide limited guidance on frequency quality for short time scales, such as less than one hour. Capturing frequency variations and events requires high time resolutions, e.g., 0.1 seconds or less, resulting in significant data storage requirements. However, power-quality monitors typically report averaged values at intervals of 10 minutes, 15 minutes, or one hour, depending on the disturbance type. To address these challenges, we propose calculating statistic indices from high-resolution data within a 15-minute or one-hour window length, thus avoiding storing high-resolution data. We apply the basic statistic indices to frequency data measured in Finland for a single day in June 2023, demonstrating their effectiveness in capturing frequency variations and two significant events during that day. © 2024 IEEE.

关键词： Time measurement

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Logarithmic-depth quantum circuits for Hamming weight projections

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Physical Review A 2024年第5期110卷 052401页

作者： Soorya Rethinasamy Margarite L. LaBorde Mark M. Wilde School of Applied and Engineering Physics Hearne Institute for Theoretical Physics and Department of Physics and Astronomy School of Electrical and Computer Engineering

A pure state of fixed Hamming weight is a superposition of computational basis states such that each bitstring in the superposition has the same number of ones. Given a Hilbert space of the form H=(C2)⊗n, or an n-qubit system, the identity operator can be decomposed as a sum of projectors onto subspaces of fixed Hamming weight. In this work, we propose several quantum algorithms that realize a coherent Hamming weight projective measurement on an input pure state, meaning that the post-measurement state of the algorithm is the projection of the input state onto the corresponding subspace of fixed Hamming weight. We analyze a depth-width tradeoff for the corresponding quantum circuits, allowing for a depth reduction of the circuits at the cost of more control qubits. For an n-qubit input, the depth-optimal algorithm uses O(n) control qubits and the corresponding circuit has depth O(log(n)), assuming that we have the ability to perform qubit resets. Furthermore, the proposed algorithm construction uses only one- and two-qubit gates.

关键词： Quantum algorithms & computation

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Optimum classical beam-position sensing

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Physical Review applied 2024年第4期22卷 L041004页

作者： Wenhua He Christos N. Gagatsos Dalziel J. Wilson Saikat Guha Wyant College of Optical Sciences Department of Electrical and Computer Engineering Program in Applied Mathematics

Beam-displacement measurements are widely used in optical sensing and communications; however, their performance is affected by numerous intrinsic and extrinsic factors, including beam profile, propagation loss, and receiver architecture. Here we present a framework for designing a classically optimal beam-displacement transceiver, using quantum estimation theory. We consider the canonical task of estimating the position of a diffraction-limited laser beam after passing through an apertured volume characterized by Fresnel-number product DF. As a rule of thumb, higher-order Gaussian modes provide more information about beam displacement, but are more sensitive to loss. Applying quantum Fisher information, we design mode combinations that optimally leverage this trade-off, and show that a greater than tenfold improvement in precision is possible, relative to the fundamental mode, for a practically relevant DF=100. We also show that this improvement is realizable with a variety of practical receiver architectures. Our findings extend previous works on lossless transceivers, may have immediate impact on applications, such as atomic force microscopy and near-field optical communication, and pave the way towards globally optimal transceivers using nonclassical laser fields.

关键词： Classical optics Metrology Quantum Fisher information Quantum optics Quantum parameter estimation Devices Wireless communication networks Atomic force microscopy

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Wigner non-negative states that verify the Wigner entropy conjecture

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Physical Review A 2024年第1期110卷 012228-012228页

作者： Qipeng Qian Christos N. Gagatsos Program in Applied Mathematics The Department of Electrical and Computer Engineering The Wyant College of Optical Sciences The

We present further progress, in the form of analytical results, on the Wigner entropy conjecture set forth by Van Herstraeten and Cerf [Phys. Rev. A 104, 042211 (2021)] and Hertz et al. [J. Phys. A: Math. Theor. 50, 385301 (2017)]. Said conjecture asserts that the differential entropy defined for non-negative, yet physical, Wigner functions is minimized by pure Gaussian states while the minimum entropy is equal to 1+lnπ. We prove this conjecture for the qubits formed by Fock states |0〉 and |1〉 that correspond to non-negative Wigner functions. In particular, we derive an explicit form of the Wigner entropy for those states lying on the boundary of the set of Wigner non-negative qubits. We then consider general mixed states and derive a sufficient condition for the conjecture's validity. Lastly, we elaborate on the states which are in accordance with our condition.

关键词： Quantum foundations Quantum information theory

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Frequency Generation for a Quantum Current Sensor in Smart Grids 26

Frequency Generation for a Quantum Current Sensor in Smart G...

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26th International Symposium on Symbolic and Numeric Algorithms for Scientific Computing, SYNASC 2024

作者： Hoffmann, Frederik Bolter, Ann-Sophie Horsthemke, Ludwig Stiegekotter, Dennis Pogorzelski, Jens Glosekotter, Peter Gregor, Markus FH Münster - University of Applied Sciences Department of Electrical Engineering and Computer Science Steinfurt48565 Germany FH Münster - University of Applied Sciences Department of Engineering Physics Steinfurt48565 Germany

ISBN: (纸本)9798331532833

Integrating renewable energy sources, electric vehicles, and storage systems into power grids demands advanced control and monitoring systems. Precise current sensors are a critical component of these systems, essential for ensuring reliable and efficient electricity distribution. Quantum sensors, particularly those based on nitrogen vacancy (NV) centers in diamond, provide a promising solution for high-precision current measurement. This document introduces an innovative method for generating microwave signals using direct digital synthesis (DDS) and field-programmable gate arrays (FPGAs) to drive multiple signals. © 2024 IEEE.

关键词： Power grids

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Dynamics of self-hybridized exciton–polaritons in 2D halide perovskites

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Light(Science & Applications) 2024年第1期13卷 13-22页

作者： Surendra B.Anantharaman Jason Lynch Christopher E.Stevens Christopher Munley Chentao Li Jin Hou Hao Zhang Andrew Torma Thomas Darlington Francis Coen Kevin Li Arka Majumdar PJames Schuck Aditya Mohite Hayk Harutyunyan Joshua R.Hendrickson Deep Jariwala Department of Electrical and Systems Engineering University of PennsylvaniaPhiladelphiaPA19104USA KBR Inc. BeavercreekOH45431USA Air Force Research Laboratory Sensors DirectorateWright-Patterson Air Force BaseOH45433USA Department of Physics University of WashingtonSeattleWA98195USA Department of Physics Emory UniversityAtlantaGA30322USA Department of Chemical and Biomolecular Engineering Rice UniversityHoustonTX77005USA Department of Materials Science and Nanoengineering Rice UniversityHoustonTX77005USA Applied Physics Program Smalley‐Curl InstituteRice UniversityHoustonTX77005USA Department of Mechanical Engineering Columbia UniversityNew YorkNY10027USA Department of Electrical and Computer Engineering University of WashingtonSeattleWA98195USA

Excitons,bound electron–hole pairs,in two-dimensional hybrid organic inorganic perovskites(2D HOIPs)are capable of forming hybrid light-matter states known as exciton-polaritons(E–Ps)when the excitonic medium is confined in an optical *** the case of 2D HOIPs,they can self-hybridize into E–Ps at specific thicknesses of the HOIP crystals that form a resonant optical cavity with the ***,the fundamental properties of these self-hybridized E–Ps in 2D HOIPs,including their role in ultrafast energy and/or charge transfer at interfaces,remain ***,we demonstrate that>0.5µm thick 2D HOIP crystals on Au substrates are capable of supporting multiple-orders of self-hybridized E–P *** E–Ps have high Q factors(>100)and modulate the optical dispersion for the crystal to enhance sub-gap absorption and *** varying excitation energy and ultrafast measurements,we also confirm energy transfer from higher energy E–Ps to lower energy E–***,we also demonstrate that E–Ps are capable of charge transport and transfer at *** findings provide new insights into charge and energy transfer in E–Ps opening new opportunities towards their manipulation for polaritonic devices.

关键词： charge polar excitation

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Incoherent meta-imaging system for noise-robust object recognition

Incoherent meta-imaging system for noise-robust object recog...

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2024 Conference on Lasers and Electro-Optics/Pacific Rim, CLEO-PR 2024

作者： Kim, Jungmin Yu, Nanfang Yu, Zongfu Department of Electrical and Computer Engineering University of Wisconsin MadisonWI53706 United States Department of Applied Physics and Applied Mathematics Columbia University New YorkNY10027 United States

We propose a meta-imaging system designed for noise-robust object recognition. By training the phase modulation of metasurfaces, the system concentrates the optical signal power, thereby enhancing the signal-to-noise ... 详细信息

关键词： Signal modulation

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