This study introduces a novel pipeline for feature extraction from Functional Magnetic Resonance Imaging (fMRI) data, focusing on age-related trends in node embeddings derived from causal brain graphs during naturalis...
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ISBN:
(数字)9798331523114
ISBN:
(纸本)9798331523121
This study introduces a novel pipeline for feature extraction from Functional Magnetic Resonance Imaging (fMRI) data, focusing on age-related trends in node embeddings derived from causal brain graphs during naturalistic stimuli (movie observation). Directed Acyclic Graphs (DAGs) constructed using the Non-combinatorial Optimization via Trace Exponential and Augmented Lagrangian for Structure learning (NOTEARS) algorithm modeled causal relationships among 25 brain regions of interest (ROIs). Graph embeddings were generated using the Deep Walk algorithm to capture low-dimensional representations of graph structures. Unlike previous studies analyzing functional brain graphs with traditional graph metrics (e.g., degree, centrality, clustering coefficient), our approach employs modern techniques to uncover patterns in effective brain graphs. The results revealed decreasing feature similarity with age in regions associated with Theory of Mind (ToM), Pain, Face and Place Processing, reflecting age-related neural changes. Conversely, the Left Retrosplenial Cortex (IRSC) demonstrated increasing similarity, suggesting enhanced maturation and efficiency in spatial memory functions. Regions like the Left Fusiform Face Area (IFF A) and Right Transverse Occipital Sulcus (rTOS) showed no significant trends, emphasizing the role of functional relevance in brain responses to naturalistic stimuli. The novelty of our research lies in analyzing localized patterns in causal brain graphs using embedding techniques like Deep Walk, moving beyond traditional metrics. For the first time, features were extracted from fMRI data to study node-level similarities across age groups during naturalistic stimuli. By combining effective graph construction with localized embedding methods, this pipeline advances age-related brain connectivity research, demonstrating the consistent impact of movie stimuli on brain dynamics and the potential of graph-based methods to reveal age-related neural connectivit
Accurate early diagnosis is crucial in addressing Age-related Macular Degeneration (AMD), a chronic retinal disease that is a leading cause of blindness among the elderly. Medical imaging, particularly fundus imaging,...
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ISBN:
(数字)9798350368741
ISBN:
(纸本)9798350368758
Accurate early diagnosis is crucial in addressing Age-related Macular Degeneration (AMD), a chronic retinal disease that is a leading cause of blindness among the elderly. Medical imaging, particularly fundus imaging, is essential in facilitating timely detection and intervention. Due to the variability in image sizes within our dataset, this paper introduces the SABiT-MNet model, which effectively discriminates between healthy retinas, dry AMD, and wet AMD. The model integrates a novel scale-adaptive (SA) approach by combining an autoencoder with Big Transfer (BiT) as its backbone. Unlike traditional resizing methods, which often result in the loss of critical diagnostic information, the SA model dynamically adjusts to varying image sizes, preserving key retinal features essential for accurate diagnosis. The primary aim of this architecture is to retain crucial details in fundus images to ensure precise classification. In this study, 648 subjects were recruited through the Comparisons of AMD Treatments Trials study group, sponsored by the University of Pennsylvania. Experimental results demonstrate that the proposed SABiT-MNet model outperforms state-of-the-art approaches, including transformer-based models, achieving superior diagnostic accuracy. The model recorded performance metrics of 94% accuracy, 97% sensitivity, and 93.94% specificity. To further validate the robustness of the system, we tested it on the public ODiR dataset, where it achieved similarly promising results, confirming the effectiveness of our approach.
1 Introduction The artificial intelligence(AI)revolution is upon us,transforming not just our daily lives with smart assistants,personalized recommendations,and autonomous systems but also profoundly altering the land...
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1 Introduction The artificial intelligence(AI)revolution is upon us,transforming not just our daily lives with smart assistants,personalized recommendations,and autonomous systems but also profoundly altering the landscape of scientific research and knowledge *** revolution is characterized by the integration of AI into every domain of human activity,from healthcare and finance to education and *** transformative effects are also being felt in the world of scientific research,e.g.,in the physical sciences,where AI is not just assisting in data analysis^(1) but is also driving new discoveries^(2) and pushing the boundaries of knowledge and applied sciences.
We design a massively-parallel broadband diffractive processor for all-optical computation of a large number (NW > 180) of arbitrarily-selected, complex-valued linear transformations by encoding the input/output of...
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We present deep learning-optimized diffractive materials forming a broadband and polarization-insensitive unidirectional imager that permits imaging along only one direction while blocking the light transmission in th...
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We demonstrate diffractive networks that perform all-optical phase recovery and synthesize the quantitative phase images of input objects by converting the input phase information into quantitative intensity variation...
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We present a diffractive optical processor that can transform input object phase profiles at multiple wavelengths into spatial intensity variations at its output, enabling single-shot multispectral quantitative phase ...
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We introduce a computational snapshot hyperspectral imager for benchtop microscopy. The compact device uses a diffuser and spectral filter array to multiplex spatio-spectral information into a 2D measurement, then rec...
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We report a diffractive super-resolution image display framework consisting of a digital encoder and an all-optical decoder to synthesize/project high-resolution images at an output plane using a low-resolution input ...
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