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arXiv 2022年

作者： Volpe, Giovanni Maragò, Onofrio M. Rubinzstein-Dunlop, Halina Pesce, Giuseppe Stilgoe, Alexander B. Volpe, Giorgio Tkachenko, Georgiy Truong, Viet Giang Chormaic, Síle Nic Kalantarifard, Fatemeh Elahi, Parviz Käll, Mikael Callegari, Agnese Marqués, Manuel I. Neves, Antonio A.R. Moreira, Wendel L. Fontes, Adriana Cesar, Carlos L. Saija, Rosalba Saidi, Abir Beck, Paul Eismann, Jörg S. Banzer, Peter Fernandes, Thales F.D. Pedaci, Francesco Bowen, Warwick P. Vaippully, Rahul Lokesh, Muruga Roy, Basudev Thalhammer, Gregor Ritsch-Marte, Monika García, Laura Pérez Arzola, Alejandro V. Castillo, Isaac Pérez Argun, Aykut Muenker, Till M. Vos, Bart E. Betz, Timo Cristiani, Ilaria Minzioni, Paolo Reece, Peter J. Wang, Fan McGloin, David Ndukaife, Justus C. Quidant, Romain Roberts, Reece P. Laplane, Cyril Volz, Thomas Gordon, Reuven Hanstorp, Dag Marmolejo, Javier Tello Bruce, Graham D. Dholakia, Kishan Li, Tongcang Brzobohatý, Oto Simpson, Stephen H. Zemánek, Pavel Ritort, Felix Roichman, Yael Bobkova, Valeriia Wittkowski, Raphael Denz, Cornelia Kumar, G.V. Pavan Foti, Antonino Donato, Maria Grazia Gucciardi, Pietro G. Gardini, L. Bianchi, G. Kashchuk, A. Capitanio, M. Paterson, Lynn Jones, P.H. Berg-Sørensen, Kirstine Barooji, Younes F. Oddershede, Lene B. Pouladian, Pegah Preece, Daryl Adiels, Caroline Beck De Luca, Anna Chiara Magazzù, A. Ciriza, D. Bronte Iatì, M.A. Swartzlander, Grover A. Department of Physics University of Gothenburg Gothenburg41296 Sweden CNR IPCF Istituto per i Processi Chimico-Fisici Messina Italy ARC CoE for Engineered Quantum Systems School of Mathematics and Physics The University of Queensland Australia Department of Chemistry University College London 20 Gordon Street LondonWC1H 0AJ United Kingdom Dipartimento di Fisica Università degli studi di Napoli Federico II Italy Okinawa Institute of Science and Technology Graduate University Japan Department of Health Technology Technical University of Denmark Lyngby Denmark Physics Department Boğaziçi University Istanbul Turkey Chalmers University of Technology Gothenburg Sweden Departamento de Física de Materiales IFIMAC Instituto Nicolás Cabrera Universidad Autónoma de Madrid Spain Santo André São Paulo Brazil Tratamento de dados geofísicos Tecnologia e processamento de geologia e geofísica Exploração Petrobras - Petróleo Brasileiro S.A. Rio de Janeiro Rio de Janeiro Brazil Pernambuco Recife Brazil Ceará Fortaleza Brazil Campinas São Paulo Brazil Dipartimento di Scienze Matematiche e Informatiche Scienze Fisiche e Scienze della Terra Università di Messina Italy Institute of Optics Information and Photonics University Erlangen-Nuremberg Staudtstr. 7/B2 ErlangenD-91058 Germany Max Planck Institute for the Science of Light Staudtstr. 2 ErlangenD-91058 Germany Institute of Physics University of Graz NAWI Graz Universitätsplatz 5 Graz8010 Austria Centre de Biologie Structurale CNRS INSERM Univ.Montpellier France Indian Institute of Technology Madras India Institute for Biomedical Physics Medical University of Innsbruck Austria Instituto de Física Universidad Nacional Autónoma de México Ciudad de MéxicoC. P. 04510 Mexico Departamento de Física Universidad Autónoma Metropolitana-Iztapalapa San Rafael Atlixco 186 Ciudad de México09340 Mexico Third Institute of Physics - Biophysics Georg August University Göttingen Germany Department of Electrical

Optical tweezers are tools made of light that enable contactless pushing, trapping, and manipulation of objects ranging from atoms to space light sails. Since the pioneering work by Arthur Ashkin in the 1970s, optical tweezers have evolved into sophisticated instruments and have been employed in a broad range of applications in life sciences, physics, and engineering. These include accurate force and torque measurement at the femtonewton level, microrheology of complex fluids, single micro- and nanoparticle spectroscopy, single-cell analysis, and statistical-physics experiments. This roadmap provides insights into current investigations involving optical forces and optical tweezers from their theoretical foundations to designs and setups. It also offers perspectives for applications to a wide range of research fields, from biophysics to space exploration. Copyright © 2022, The Authors. All rights reserved.

关键词： Optical tweezers

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OpenWSI: A low-cost, high-throughput whole slide imaging system via single-frame autofocusing and open-source hardware

arXiv

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arXiv 2019年

作者： Guo, Chengfei Bian, Zichao Jiang, Shaowei Murphy, Michael Zhu, Jiakai Wang, Ruihai Song, Pengming Shao, Xiaopeng Zhang, Yongbing Zheng, Guoan Department of Biomedical Engineering University of Connecticut StorrsCT06269 United States Department of Electrical and Computer Engineering University of Connecticut StorrsCT06269 United States Department of Dermatology University of Connecticut Health Center FarmingtonCT06030 United States School of Physics and Optoelectronic Engineering Xidian University Shaanxi710071 China Graduate School at Shenzhen Tsinghua University Shenzhen518055 China

Recent advancements in whole slide imaging (WSI) have moved pathology closer to digital practice. Existing systems require precise mechanical control and the cost is prohibitive for most individual pathologists. Here we report a low-cost and high-throughput WSI system termed OpenWSI. The reported system is built using off-the-shelf components including a programmable LED array, a photographic lens, and a low-cost computer numerical control (CNC) router. Different from conventional WSI platforms, our system performs real-time single-frame autofocusing using color-multiplexed illumination. For axial positioning control, we perform coarse adjustment using the CNC router and precise adjustment using the ultrasonic motor ring in the photographic lens. By using a 20X objective lens, we show that the OpenWSI system has a resolution of ~0.7 µm. It can acquire whole slide images of a 225-mm2 region in ~2 mins, with throughput comparable to existing high-end platforms. The reported system offers a turnkey solution to transform the high-end WSI platforms into one that can be made broadly available and utilizable without loss of capacity. Copyright © 2019, The Authors. All rights reserved.

关键词： computer control systems

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Single Layer & Multi-layer Long Short-Term Memory (LSTM) Model with Intermediate Variables for Weather Forecasting 3

Single Layer & Multi-layer Long Short-Term Memory (LSTM) Mod...

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3rd International Conference on computer Science and Computational Intelligence, ICCSCI 2018

作者： Salman, Afan Galih Heryadi, Yaya Abdurahman, Edi Suparta, Wayan Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program Doctor of Computer Science Bina Nusantara University Jakarta11480 Indonesia Department of Electrical Engineering Faculty of Science and Technology Sanata Dharma University Yogyakarta55282 Indonesia

Weather forecasting has gained attention many researchers from various research communities due to its effect to the global human life. The emerging deep learning techniques in the last decade coupled and the wide availability of massive weather observation data have motivated many researches to explore hidden hierarchical pattern in the large volume of weather dataset for weather forecasting. The purposes of this research are to build a robust and adaptive statistical model for forecasting univariate weather variable in Indonesian airport area and to explore the effect of intermediate weather variable related to accuracy prediction using single layer Long Short Memory Model (LSTM) model and multi layers LSTM model. The proposed forecasting model is an extension of LSTM model by adding intermediate variable signal into LSTM memory block. The premise is that two highly related patterns in input dataset will rectify the input patterns so make it easier for the model to learn and recognize the pattern from the training dataset. In an effort to achieve a robust model for learning and recognizing weather pattern, this research will also explore various architectures such as single layer LSTM and Multiple Layer LSTM (4 layers LSTM). The dataset is weather variable data collected by Weather Underground at Hang Nadim Indonesia airport. This research used visibility as predicted data and temperature, pressure, humidity, dew point as intermediates data. The best model of LSTM in this experiment is multiple layers LSTM and the best intermediate data is pressure variable. Using the pressure variable this model has gained the validation accuracy 0.8060 and RMSE 0.0775. © 2018 The Authors. Published by Elsevier Ltd.

关键词： Long short-term memory

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Quantum computing hardware for HEP algorithms and sensing

arXiv

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arXiv 2022年

作者： Alam, M. Sohaib Belomestnykh, Sergey Bornman, Nicholas Cancelo, Gustavo Chao, Yu-Chiu Checchin, Mattia Dinh, Vinh San Grassellino, Anna Gustafson, Erik J. Harnik, Roni McRae, Corey Rae Harrington Huang, Ziwen Kapoor, Keshav Kim, Taeyoon Kowalkowski, James B. Kramer, Matthew J. Krasnikova, Yulia Kumar, Prem Kurkcuoglu, Doga Murat Lamm, Henry Lyon, Adam L. Milathianaki, Despina Murthy, Akshay Mutus, Josh Nekrashevich, Ivan Oh, JinSu Özgüler, A. Barış Perdue, Gabriel Nathan Reagor, Matthew Romanenko, Alexander Sauls, James A. Stefanazzi, Leandro Tubman, Norm M. Venturelli, Davide Wang, Changqing You, Xinyuan van Zanten, David M.T. Zhou, Lin Zhu, Shaojiang Zorzetti, Silvia NASA Ames Research Center Moffett FieldCA94035 United States Mountain ViewCA94043 United States Fermi National Accelerator Laboratory BataviaIL60510 United States Scientific Computing Division Fermi National Accelerator Laboratory BataviaIL60510 United States Northwestern-Fermilab Center for Applied Physics and Superconducting Technologies Northwestern University EvanstonIL60208 United States Graduate Program in Applied Physics Northwestern University EvanstonIL60208 United States Theory Division Fermi National Accelerator Laboratory BataviaIL60510 United States Department of Physics Department of Electrical Computer and Energy Engineering University of Colorado Boulder CO80305 United States National Institute of Standards and Technology Boulder CO80305 United States Department of Physics and Astronomy Northwestern University EvanstonIL60208 United States Ames Laboratory U.S. Department of Energy AmesIA50011 United States Center for Photonic Communication and Computing ECE Department Northwestern University EvanstonIL60208 United States Rigetti Computing Inc. BerkeleyCA94710 United States NASA Ames Research Center Moffett FieldCA94035 United States

Quantum information science harnesses the principles of quantum mechanics to realize computational algorithms with complexities vastly intractable by current computer platforms. Typical applications range from quantum chemistry to optimization problems and also include simulations for high energy physics. The recent maturing of quantum hardware has triggered preliminary explorations by several institutions (including Fermilab) of quantum hardware capable of demonstrating quantum advantage in multiple domains, from quantum computing to communications, to sensing. The Superconducting Quantum Materials and Systems (SQMS) Center, led by Fermilab, is dedicated to providing breakthroughs in quantum computing and sensing, mediating quantum engineering and HEP based material science. The main goal of the Center is to deploy quantum systems with superior performance tailored to the algorithms used in high energy physics. In this Snowmass paper, we discuss the two most promising superconducting quantum architectures for HEP algorithms, i.e. three-level systems (qutrits) supported by transmon devices coupled to planar devices and multi-level systems (qudits with arbitrary N energy levels) supported by superconducting 3D cavities. For each architecture, we demonstrate exemplary HEP algorithms and identify the current challenges, ongoing work and future opportunities. Furthermore, we discuss the prospects and complexities of interconnecting the different architectures and individual computational nodes. Finally, we review several different strategies of error protection and correction and discuss their potential to improve the performance of the two architectures. This whitepaper seeks to reach out to the HEP community and drive progress in both HEP research and QIS hardware. Copyright © 2022, The Authors. All rights reserved.

关键词： High energy physics

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Optomechanically Induced Birefringence and Optomechanically Induced Faraday Effect

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Physical Review Letters 2019年第2期123卷 023602-023602页

作者： Robert Duggan Javier del Pino Ewold Verhagen Andrea Alù Department of Electrical and Computer Engineering The University of Texas at Austin Austin Texas 78712 USA Center for Nanophotonics AMOLF Science Park 104 1098 XG Amsterdam The Netherlands Photonics Initiative Advanced Science Research Center City University of New York New York 10031 USA Physics Program Graduate Center City University of New York New York 10016 USA Department of Electrical Engineering City College of The City University of New York New York 10031 USA

We demonstrate an optomechanical platform where optical mode conversion mediated by mechanical motion enables the arbitrary tailoring of polarization states of propagating light fields. Optomechanical interactions are realized in a Fabry-Pérot resonator, which naturally supports two polarization-degenerate states while an optical control field induces rotational symmetry breaking. Applying such principles, the entire Poincaré sphere is spanned by just optical control of the driving field, realizing reciprocal and nonreciprocal optomechanically induced birefringence for linearly polarized and circularly polarized control driving. A straightforward extension of this setup also enables all-optical tunable isolation and circulation. Our findings open new avenues to exploit optomechanics for the arbitrary manipulation of light polarization.

关键词： Nonlinear optics Optomechanics

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Corrigendum: Human microvascular reactivity: a review of vasomodulating stimuli and non-invasive imaging assessment (2021 Physiol. Meas.42 09TR01)

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Physiological measurement 2021年第10期42卷 109501-109501页

作者： Aaron M Troy Hai-Ling Margaret Cheng Institute of Biomedical Engineering University of Toronto Canada. Ted Rogers Centre for Heart Research Translational Biology & Engineering Program Toronto Canada. Cardiovascular Sciences Collaborative Specialization University of Toronto Canada. The Edward S. Rogers Sr Department of Electrical and Computer Engineering University of Toronto Canada. Heart & Stroke/Richard Lewar Centre of Excellence for Cardiovascular Research Toronto Canada. Ontario Institute for Regenerative Medicine Toronto Canada.

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In vivo percutaneous reflectance spectroscopy of fatty liver development in rats suggests that the elevation of the scattering power is an early indicator of hepatic steatosis

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Journal of Innovative Optical Health Sciences 2018年第4期11卷 53-71页

作者： Daqing Piao Jerry W.Ritchey GReed Holyoak Corey R.Wall Nigar Sultana Jill K.Murray Kenneth E.Bartels School of Electrical and Computer Engineering Oklahoma State University 202 Engineering South StillwaterOK 74078USA Department of Veterinary Clinical Sciences Center for Veterinary Health Sciences 002 VTH Oklahoma State University StillwaterOK 74078USA Department of Veterinary Pathobiology Center for Veterinary Health Sciences Oklahoma State University 250 McElroy Hall StillwaterOK 74078USA Graduate Program on Interdisciplinary Sciences Oklahoma State University StillwaterOK 74078USA

This study assessed whether there was a scat tering spectral mar ker quantifiable by reflectance measurements that could indicate early development of hepatic steatosis in rats for potential applications to pre procurement organ *** rats were fed a methionine choline-deficient(MCD)diet and eight rats were fed a normal *** assessment of the liver parenchyma of rats in vivo was performed by percut aneous reflect ance spectroscopy using a single fiber probe at the beginning of diet-intake and arbitrary post-diet-intake times up to 11 weeks to render longitudinal *** sampling of the liver over the duration of diet adm inistration was performed on two MCD diet treated rats and one control rat eutha-nized after reflectance spectroscopy *** images of hematoxylin/eosin-stained liver specimens were analyzed morphometrically to evahuate the lipid size changes associated with the level of *** MCD-diet-treated group(n=16)had mild steatosis in seven rats,moderate in three rats,severe in six rats,and no other significant *** control rats(n=8)developed hepatic *** the parameters retrieved from per-SfS,only the scat tering power(can be either positive or negative)appeared to be statist ically diferent between MCD-treated and control *** scattering power for the 16 MCD-diet-treated livers at the time of euthanasia and presenting various levels of steatosis was 033±0.21,in comparison to 0.036±0.25 of the eight control livers(p=0.0189).When evaluated at days 12 and 13 combined,the scattering power of the 16 MCD-diet-treated livers was 032±0.17,in comparison to 0.10±0.11 of the eight control livers(p=0.0017).All of four MCD-treated livers harvested at days 12 and 13 presented mild steatosis with sub-micron size lipid droplets,even though none of the MCD-treated livers were sonogr aphically remarkable for fatty *** elevation of the scattering power may be a valuable marker indicating ear

关键词： Hepatic steatosis difuse reflect ance spectroscopy liver transplant

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Erratum for Wang et al., "Clinically Applicable System for Rapidly Predicting Enterococcus faecium Susceptibility to Vancomycin"

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Microbiology spectrum 2022年第1期10卷 e0261021页

作者： Hsin-Yao Wang Chia-Ru Chung Chao-Jung Chen Ko-Pei Lu Yi-Ju Tseng Tzu-Hao Chang Min-Hsien Wu Wan-Ting Huang Ting-Wei Lin Tsui-Ping Liu Tzong-Yi Lee Jorng-Tzong Horng Jang-Jih Lu Department of Laboratory Medicine Chang Gung Memorial Hospitalgrid.413801.f at Linkou Taoyuan City Taiwan. Ph.D. Program in Biomedical Engineering Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Computer Science and Information Engineering National Central Universitygrid.37589.30 Taoyuan City Taiwan. Graduate Institute of Integrated Medicine China Medical Universitygrid.254145.3 Taichung Taiwan. Proteomics Core Laboratory China Medical Universitygrid.254145.3 Hospital Taichung Taiwan. Graduate Program in Biomedical Information Yuan-Ze University Taoyuan City Taiwan. Department of Information Management Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Graduate Institute of Biomedical Informatics Taipei Medical University Taipei City Taiwan. Clinical Big Data Research Center Taipei Medical University Hospital Taipei City Taiwan. Graduate Institute of Biomedical Engineering Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Division of Haematology/Oncology Department of Internal Medicine Chang Gung Memorial Hospitalgrid.413801.f at Linkou Taoyuan City Taiwan. Biosensor Group Biomedical Engineering Research Center Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Pathology Kaohsiung Chang Gung Memorial Hospitalgrid.413801.f and Chang Gung University College of Medicine Kaohsiung Taiwan. School of Life and Health Sciences The Chinese University of Hong Kong Shenzhen China. Warshel Institute for Computational Biology The Chinese University of Hong Kong Shenzhen China. Department of Bioinformatics and Medical Engineering Asia University Taichung City Taiwan. School of Medicine Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Medical Biotechnology and Laboratory Science Chang Gung Universitygrid.145695.a Taoyuan City Taiwan.

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Stretchable Electronics: Rubbery Electronics Fully Made of Stretchable Elastomeric Electronic Materials (Adv. Mater. 15/2020)

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Advanced Materials 2020年第15期32卷

作者： Kyoseung Sim Zhoulyu Rao Faheem Ershad Cunjiang Yu Department of Mechanical Engineering University of Houston Houston TX 77204 USA Materials Science and Engineering Program University of Houston Houston TX 77204 USA Department of Biomedical Engineering University of Houston Houston TX 77204 USA Department of Electrical and Computer Engineering Texas Center for Superconductivity University of Houston Houston TX 77204 USA

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Author Correction: Disrupting cellular memory to overcome drug resistance

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Nature communications 2024年第1期15卷 4264页

作者： Guillaume Harmange Raúl A Reyes Hueros Dylan L Schaff Benjamin Emert Michael Saint-Antoine Laura C Kim Zijian Niu Shivani Nellore Mitchell E Fane Gretchen M Alicea Ashani T Weeraratna M Celeste Simon Abhyudai Singh Sydney M Shaffer Cellular and Molecular Biology Graduate Group Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Department of Biochemistry and Molecular Biophysics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Department of Bioengineering School of Engineering and Applied Sciences University of Pennsylvania Philadelphia PA USA. Division of Biology and Biological Engineering California Institute of Technology Pasadena CA 91125 USA. Department of Electrical and Computer Engineering University of Delaware Newark DE 19716 USA. Abramson Family Cancer Research Institute Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Department of Chemistry College of the Arts and Sciences University of Pennsylvania Philadelphia PA USA. Department of Physics College of the Arts and Sciences University of Pennsylvania Philadelphia PA USA. Department of Biology College of the Arts and Sciences University of Pennsylvania Philadelphia PA USA. The Wharton School University of Pennsylvania Philadelphia PA USA. Cancer Signaling and Microenvironment Research Program Fox Chase Cancer Center Philadelphia PA USA. Department of Biochemistry and Molecular Biology Johns Hopkins School of Public Health Baltimore MD USA. Sidney Kimmel Cancer Center Johns Hopkins School of Medicine Baltimore MD USA. Department of Cell and Developmental Biology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Department of Bioengineering School of Engineering and Applied Sciences University of Pennsylvania Philadelphia PA USA. sydshaffer@***. Department of Pathology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. sydshaffer@***.

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