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Light(Science & Applications) 2015年第1期4卷 267-273页

作者： Jun Ho Son Byungrae Cho SoonGweon Hong Sang Hun Lee Ori Hoxha Amanda J Haack Luke P Lee Department of Bioengineering University of CaliforniaBerkeleyCA 94720USA Berkeley Sensor and Actuator Center University of CaliforniaBerkeleyCA 94720USA Department of Electrical Engineering and Computer Sciences University of CaliforniaBerkeleyCA 94720USA Biophysics Graduate Program University of CaliforniaBerkeleyCA 94720USA

Nucleic acid amplification and quantification via polymerase chain reaction(PCR)is one of the most sensitive and powerful tools for clinical laboratories,precision medicine,personalized medicine,agricultural science,forensic science and environmental *** multiplex PCR,characterized by low power consumption,compact size and simple operation,is ideal for timely diagnosis at the point-of-care(POC).Although several fast/ultrafast PCR methods have been proposed,the use of a simple and robust PCR thermal cycler remains challenging for POC ***,we present an ultrafast photonic PCR method using plasmonic photothermal light-to-heat conversion via photon–electron–phonon *** demonstrate an efficient photonic heat converter using a thin gold(Au)film due to its plasmon-assisted high optical absorption(approximately 65%at 450 nm,the peak wavelength of heat source light-emitting diodes(LEDs)).The plasmon-excited Au film is capable of rapidly heating the surrounding solution to over 150℃ within 3 *** this method,ultrafast thermal cycling(30 cycles;heating and cooling rate of 12.7960.93℃ s^(-1) and 6.660.29℃ s^(-1),respectively)from 55℃(temperature of annealing)to 95℃(temperature of denaturation)is accomplished within 5 *** photonic PCR thermal cycles,we demonstrate here successful nucleic acid(λ-DNA)*** simple,robust and low cost approach to ultrafast PCR using an efficient photonic-based heating procedure could be generally integrated into a variety of devices or procedures,including on-chip thermal lysis and heating for isothermal amplifications.

关键词： genomics light-emitting diodes(LEDs) molecular diagnostics personalized medicine plasmonics point-of-care(POC)diagnostics polymerase chain reaction(PCR)

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A mobile indoor positioning system based on iBeacon technology 37

A mobile indoor positioning system based on iBeacon technolo...

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37th Annual International Conference of the IEEE engineering in Medicine and Biology Society, EMBC 2015

作者： Lin, Xin-Yu Ho, Te-Wei Fang, Cheng-Chung Yen, Zui-Shen Yang, Bey-Jing Lai, Feipei Graduate Institute of Biomedical Electronics and Bioinformatics Taipei Taiwan Dept. of Electrical Engineering Taipei Taiwan Department of Computer Science and Information Engineering National Taiwan University Taiwan Department of Emergency Medicine National Taiwan University Hospital Taipei Taiwan

ISBN: (纸本)9781424492718

To increase the efficiency in the emergency room, the goal of this research is to implement a mobile-based indoor positioning system using mobile applications (APP) with the iBeacon solution based on the Bluetooth Low Energy (BLE) technology. We use the Received Signal Strength (RSS) based localization method to estimate the patients' locations. Our positioning algorithm achieves 97.22% (95% Confidence Interval = 95.90% - 98.55%) accuracy of classification. As the result, our mechanism is reliable enough to satisfy the need for medical staff to track the locations of their patients. © 2015 IEEE.

关键词： Bluetooth Low Energy Indoor positioning mobile application

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A Computational Primitive for Convolution based on Coupled Oscillator Arrays

A Computational Primitive for Convolution based on Coupled O...

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IEEE computer Society Annual Symposium on VLSI

作者： Donald M. Chiarulli Brandon Jennings Yan Fang Andrew Seel Steven P. Levitan Department of Computer Science Computer Engineering Graduate Program Department of Electrical and Computer Engineering University of Pittsburgh Pittsburgh PA

In this paper we present a new computational primitive for convolution using coupled oscillator arrays. It is based on a Degree of Match (DOM) operation for pairs of vectors of analog voltage encoded data. The convolution operation is synthesized from these DOM circuits and computes the precise mathematical convolution of the two vectors. We present an example circuit design for the DOM operator and SPICE simulations of the circuit behavior. A MATLAB model is curve fit to an inverted copy of this output and shown to be roughly equivalent to the square of the Euclidian distance between the vectors. Using a parameterized version of this model we conducted a MATLAB study to analyze the accuracy of the DOM and convolution operations under variations in oscillator array symmetry, locking range, and additive noise. We also show a small example of convolution with an edge enhancement filter.

关键词： Very large scale integration

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26th Annual Computational Neuroscience Meeting (CNS*2017) of the Organization for Computational Neuroscience Antwerp, Belgium, July 15-20, 2017

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BMC NEUROSCIENCE 2017年第SUPPL 1期18卷 59-59页

作者： [Anonymous] Indiana University Purdue University Indianapolis Indianapolis IN 46032 USA Stark Neurosciences Research Institute Indiana University School of Medicine Indianapolis IN 46032 USA Department of Mathematics East Carolina University Greenville NC 27858 USA Jülich Supercomputing Centre Forschungszentrum Jülich 52425 Jülich Germany Future Systems Swiss National Supercomputing Centre 8092 Zurich Switzerland User Engagement and Support Swiss National Supercomputing Centre 6900 Lugano Switzerland Institut de Neurosciences des Systèmes Aix Marseille Univ 13005 Marseille France Simulation Lab Neuroscience Forschungszentrum Jülich Jülich Germany Department of Experimental Psychology Ghent University 9000 Ghent Belgium Donders Center for Cognitive Neuroimaging Radboud University 6525HR Nijmegen The Netherlands Department of Electrical Computer and Energy Engineering University of Colorado Boulder CO 80309 USA Department of Neurosurgery Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Neurology Johns Hopkins School of Medicine Baltimore MD 21287 USA Department of Otolaryngology Johns Hopkins School of Medicine Baltimore MD 21287 USA INSERM U968 Paris France Sorbonne Universités UPMC University Paris 06 UMR_S 968 Institut de la Vision Paris France CNRS UMR_7210 Paris France Department of Computer Architecture and Technology University of Granada (CITIC) Granada Spain Sorbonne Universités UPMC Univ Paris 06 INSERM CNRS Institut de la Vision Paris France Department of Adaptive Machine Systems Osaka University Osaka Japan Department of Computer Science University of Cergy-Pontoise Cergy-Pontoise France Department of Physics and Astronomy College of Charleston Charleston SC 29424 USA School of Physics Faculty of Science University of Sydney Sydney NSW 2006 Australia Center of Excellence for Integrative Brain Function Australian Research Council Sydney Australia Max Planck Institute for Human Cognitive and Brain Sciences Saxony Lei

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Transient Electronics: Dry Transient Electronic Systems by Use of Materials that Sublime (Adv. Funct. Mater. 12/2017)

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Advanced Functional Materials 2017年第12期27卷

作者： Bong Hoon Kim Jae‐Hwan Kim Luana Persano Suk‐Won Hwang Seungmin Lee Jungyup Lee Yongjoon Yu Yongseon Kang Sang M. Won Jahyun Koo Youn Kyoung Cho Gyum Hur Anthony Banks Jun‐Kyul Song Phillip Won Young Min Song Kyung‐In Jang Daeshik Kang Chi Hwan Lee Dario Pisignano John A. Rogers Departments of Materials Science and Engineering Biomedical Engineering Chemistry Neurological Surgery Mechanical Engineering Electrical Engineering and Computer Science Simpson Querrey Institute and Feinberg Medical School Center for Bio‐Integrated Electronics Northwestern University Evanston IL 60208 USA Department of Materials Science and Engineering Frederick Seitz Materials Research Laboratory University of Illinois at Urbana‐Champaign Urbana IL 61801 USA NEST Istituto Nanoscienze‐CNR Piazza S. Silvestro 12 I‐56127 Pisa Italy KU‐KIST Graduate School of Converging Science and Technology Korea University Seoul 02841 Republic of Korea School of Electrical Engineering and Computer Science Gwangju Institute of Science and Technology (GIST) Gwangju 61005 Republic of Korea Department of Robotics Engineering Daegu Gyeongbuk Institute of Science and Technology (DGIST) Daegu 42988 Republic of Korea Department of Mechanical Engineering Ajou University Suwon 443–749 Republic of Korea Weldon School of Biomedical Engineering School of Mechanical Engineering The Center for Implantable Devices and Birck Nanotechnology Center Purdue University West Lafayette IN 47907 USA Dipartimento di Matematica e Fisica “Ennio De Giorgi” Università del Salento Via Arnesano I‐73100 Lecce Italy

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Author Correction: Evaluating Tumor Evolution via Genomic Profiling of Individual Tumor Spheroids in a Malignant Ascites

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Scientific reports 2018年第1期8卷 17395页

作者： Sungsik Kim Soochi Kim Jinhyun Kim Boyun Kim Se Ik Kim Min A Kim Sunghoon Kwon Yong Sang Song Department of Electrical and Computer Engineering Seoul National University Seoul 08826 Republic of Korea. Interdisciplinary Program for Bioengineering Seoul National University Seoul 08826 Republic of Korea. Seoul National University Hospital Biomedical Research Institute Seoul National University Hospital Seoul 03080 Republic of Korea. Cancer Research Institute Seoul National University College of Medicine Seoul 03080 Republic of Korea. Department of Anesthesiology McGovern Medical School The University of Texas Health Science Center at Houston Houston TX USA. Department of Obstetrics and Gynecology Seoul National University College of Medicine Seoul 03080 Republic of Korea. Department of Pathology Seoul National University College of Medicine Seoul 03080 Republic of Korea. Department of Electrical and Computer Engineering Seoul National University Seoul 08826 Republic of Korea. skwon@snu.ac.kr. Institutes of Entrepreneurial BioConvergence Seoul National University Seoul 08826 Republic of Korea. skwon@snu.ac.kr. Seoul National University Hospital Biomedical Research Institute Seoul National University Hospital Seoul 03080 Republic of Korea. skwon@snu.ac.kr. Cancer Research Institute Seoul National University College of Medicine Seoul 03080 Republic of Korea. yssong@snu.ac.kr. Department of Obstetrics and Gynecology Seoul National University College of Medicine Seoul 03080 Republic of Korea. yssong@snu.ac.kr. Interdisciplinary Program in Cancer Biology Seoul National University College of Medicine Seoul 03080 Republic of Korea. yssong@snu.ac.kr. Biomodulation Department of Agricultural Biotechnology Seoul National University Seoul 03080 Republic of Korea. yssong@snu.ac.kr.

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

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Automated, high throughput exploration of process–structure–property relationships using the MapReduce paradigm

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Materials Discovery 2015年 1卷 21-28页

作者： Wodo, Olga Zola, Jaroslaw Sarath Pokuri, Balaji Sesha Du, Pengfei Ganapathysubramanian, Baskar University at Buffalo Materials Design and Innovation Department Buffalo United States University at Buffalo Mechanical and Aerospace Engineering Department Buffalo United States University at Buffalo Computational and Data-Enabled Science and Engineering Program Buffalo United States University at Buffalo Computer Science and Engineering Department Buffalo United States University at Buffalo Biomedical Informatics Department Buffalo United States Iowa State University Mechanical Engineering Department Ames United States Iowa State University Electrical and Computer Engineering Department Ames United States

The microstructure of a material intimately affects the performance of a device made from this material. The microstructure, in turn, is affected by the processing pathway used to fabricate the device. This forms the process–structure–property triangle that is central to material science. There has been increasing interest to comprehensively understand and subsequently exploit process–structure–property (PSP) relationships to design processing pathways that result in tailored microstructures exhibiting optimal properties. However, unraveling process–structure–property relationships usually requires systematic and tedious combinatorial search of process and system variables to identify the microstructures that are produced. This is further complicated by the necessity to interrogate the properties of the huge set of corresponding microstructures. Motivated by this challenge, we focus on developing a generic methodology to establish and explore PSP pathways. We leverage recent advances in high performance computing (HPC) and high throughput computing (HTC) with the premise that a domain expert should be able to focus on domain specific PSP problems while the highly specialized HPC/HTC knowledge needed to approach such problems should be hidden from the domain expert. Our hypothesis is that PSP exploration can be naturally formulated in terms of a standard paradigm in cloud computing, namely the MapReduce programming model. We show how reformulating PSP exploration into a MapReduce workflow enables us to take advantage of advances in cloud computing while requiring minimal specialized knowledge of HPC. We illustrate this generic approach by exploring PSP relationships relevant to organic photovoltaics. We focus on identifying microstructural traits that correlate with specific properties of the photovoltaic process: exciton generation, exciton dissociation and charge generation. We integrate a graph-based microstructure characterization tool, and a microstructure-aware

关键词： Drift diffusion model High throughput analysis MapReduce paradigm Organic solar cells Process–structure–processing Thermal annealing

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High-speed 3D brain activity quantification with compressive light-field microscopy

High-speed 3D brain activity quantification with compressive...

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Novel Techniques in Microscopy, NTM 2015

作者： Pégard, Nicolas Lyall, Evan Mardinly, Alan Antipa, Nick Waller, Laura Adesnik, Hillel Department of Molecular and Cell Biology UC Berkeley CA United States Department of Electrical Engineering and Computer Science UC Berkeley CA United States Biophysics Graduate Program UC Berkeley CA United States

We present a non-imaging light-field microscopy method for volume quantification of neural activity in scattering brain tissue. Individual neuron fluorescence is computed directly by independent component identificati... 详细信息

ISBN: (纸本)9781557529541

关键词： Time domain analysis

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International Society for Therapeutic Ultrasound Conference 2016

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Journal of Therapeutic Ultrasound 2017年第1期5卷 1-114页

作者： Brian Fowlkes Pejman Ghanouni Narendra Sanghvi Constantin Coussios Paul C. Lyon Michael Gray Christophoros Mannaris Marie de Saint Victor Eleanor Stride Robin Cleveland Robert Carlisle Feng Wu Mark Middleton Fergus Gleeson Jean-Franҫois Aubry Kim Butts Pauly Chrit Moonen Jacob Vortman Shirley Sharabi Dianne Daniels David Last David Guez Yoav Levy Alexander Volovick Javier Grinfeld Itay Rachmilevich Talia Amar Zion Zibly Yael Mardor Sagi Harnof Michael Plaksin Yoni Weissler Shy Shoham Eitan Kimmel Omer Naor Nairouz Farah Dong-Guk Paeng Zhiyuan Xu John Snell Anders H. Quigg Matthew Eames Changzhu Jin Ashli C. Everstine Jason P. Sheehan Beatriz S. Lopes Neal Kassell Thomas Looi Vera Khokhlova Charles Mougenot Kullervo Hynynen James Drake Michael Slayton Richard C. Amodei Keegan Compton Ashley McNelly Daniel Latt John Kearney David Melodelima Aurelien Dupre Yao Chen David Perol Jeremy Vincenot Jean-Yves Chapelon Michel Rivoire Wei Guo Guoxin Ren Guofeng Shen Michael Neidrauer Leonid Zubkov Michael S. Weingarten David J. Margolis Peter A. Lewin Nathan McDannold Jonathan Sutton Natalia Vykhodtseva Margaret Livingstone Thiele Kobus Yong-Zhi Zhang Michael Schwartz Yuexi Huang Nir Lipsman Jennifer Jain Martin Chapman Tejas Sankar Andres Lozano Robert Yeung Christakis Damianou Nikolaos Papadopoulos Omer Brokman Eyal Zadicario Ori Brenner David Castel Shih-Ying Wu Julien Grondin Wenlan Zheng Marc Heidmann Maria Eleni Karakatsani Carlos J. Sierra Sánchez Vincent Ferrera Elisa E. Konofagou Marinos Yiannakou HongSeok Cho Hwayoun Lee Mun Han Jong-Ryul Choi Taekwan Lee Sanghyun Ahn Yongmin Chang Juyoung Park Nicholas Ellens Ari Partanen Keyvan Farahani Raag Airan Alexandre Carpentier Michael Canney Alexandre Vignot Cyril Lafon Jean-yves Delattre Ahmed Idbaih Henrik Odéen Bradley Bolster Eun Kee Jeong Dennis L. Parker Pooja Gaur Xue Feng Samuel Fielden Craig Meyer Beat Werner William Grissom Michael Marx Hans Weber Valentina Taviani Brian Hargreaves Jun Tanaka Kentaro Kikuchi Ayumu Ishijima Takashi Azuma Kosuke Minamihata Satoshi Basic Radiological Sciences Division Department of Radiology University of Michigan Ann Arbor USA Stanford School of Medicine Stanford USA SonaCare Medical Indianapolis USA Institute of Biomedical Engineering University of Oxford Oxford UK HIFU Unit Churchill Hospital Oxford UK Department of Oncology University of Oxford Oxford UK Department of Radiology Churchill Hospital Oxford UK Institut Langevin Paris France Center for Imaging Sciences Imaging Division University Medical Center Utrecht The Netherlands InSighTec Haifa Israel Sheba Medical Center Ramat-Gan Israel Tel-Aviv University Tel-Aviv Israel Faculty of Biomedical Engineering & Russell Berrie Nanotechnology Institute Technion – Israel Institute of Technology Haifa Israel ELSC Center for Brain Sciences Hebrew University Jerusalem Israel Biomedical Engineering Technion- Israel Institute of Technology Haifa Israel Faculty of Life Sciences Bar Ilan University Ramat Gan Israel Focused Ultrasound Foundation Charlottesville USA Ocean System Engineering Jeju National University Jeju Republic of Korea Neurosurgery University of Virginia Charlottesville USA Biology University of Virginia Charlottesville USA Pathology University of Virginia Charlottesville USA Hospital for Sick Children Toronto Canada University of Toronto Toronto Canada University of Washington Seattle USA Philips Healthcare Markham Canada Sunnybrook Research Institute Toronto Canada Guided Therapy Systems LLC Mesa USA School of Medicine University of Arizona Tucson USA The CORE Institute Phoenix USA LabTAU - U1032 INSERM Lyon France Centre Leon Berard Lyon France Department of Oral Maxillofacial and Head Neck Oncology Shanghai 9th People’s Hospital Shanghai China The School of Biomedical Engineering Science and Health Systems Drexel University Philadelphia USA Department of Surgery College of Medicine Drexel University Philadelphia USA Biostatistics and Epidemiology University of Pennsylvania Philadelphi

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A secure authorization system in PHR based on CP-ABE

A secure authorization system in PHR based on CP-ABE

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E-Health and Bioengineering Conference (EHB)

作者： Ho Hui Chung Peter Shaojui Wang Te-Wei Ho Hsu-Chun Hsiao Feipei Lai Department of Computer Science and Information Engineering Graduate Institute of Biomedical Electronics and Bioinformatics Department of Electrical Engineering National Taiwan University Taipei Taiwan

In this paper, we proposed a method based on the Ciphertext-Policy Attribute-Based Encryption (CP-ABE) to dynamically authorize the user according to their private keys. The key feature of our model is the users do not have to involve in key revocation process. Our model utilizes an additional Key Management Server (KMS) which uses the lazy revocation technique and additional attribute keys to perform effective user revocation. It enables the cloud to differentiate user authentication sessions to protect their keys from different session attackers and this approach could perform direct user revocations from a group without user interventions. The operation does not require re-encryption of existing ciphertext. Our method supports backward and perfect forward secrecy and is escrow-free. Lastly, we present that our method is secure under the chosen identity key attack.

关键词： Encryption Servers Hospitals Cloud computing Authorization Games

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