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International Workshop on Design of Reliable Communication Networks (DRCN)

作者： Teresa Gomes David Tipper Abdulaziz Alashaikh Department of Electrical and Computer Engineering University of Coimbra / INESC Coimbra Coimbra Portugal Graduate Telecommunications and Networking Program University of Pittsburgh Pittsburgh PA

Telecommunications networks need to guarantee that all node pairs involved in critical service communications are highly available. Typically only a small fraction of traffic and users needs high levels of availability but this traffic often drives the network design to over engineering. In this paper we adopt a novel approach to the problem of how to provide high levels of availability in an efficient manner. The basic idea is to embed a high availability set of links and nodes (termed the spine) in the network topology and leverage protection and routing to provide differentiated classes of resilience with varying levels of availability. In this paper we first explore the spine concept through a simple example illustrating the potential benefits of the approach. Then we study how the structural properties of a network topology can be used to determine heuristics to select a suitable spine and compare this with the case where all network components have the same availability. This is followed by a numerical based study comparing the heuristics with all possible spanning tree based spines for sample topologies. Our results are a step along the path of how to best design a physical network to support protection methods in achieving high levels of availability cost efficiently.

关键词： Availability Network topology Resilience Equations Mathematical model Routing Gold

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Gamma (30-80Hz) Bicoherence Distinguishes Seizures in the Human Epileptic Brain

Gamma (30-80Hz) Bicoherence Distinguishes Seizures in the Hu...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Marija Cotic Yotin Chinvarun Mirna Guirgis Peter L. Carlen Berj L. Bardakjian Institute of Biomaterials and Biomedical Engineering University of Toronto Comprehensive Epilepsy Program Phramongkutklao Hospital Toronto Western Research Institute Edward S. Rogers Sr. Department of Electrical and Computer Engineering and the Institute of Biomaterials and Biomedical Engineering University of Toronto

ISBN: (纸本)9781424479276

We have applied wavelet bicoherence (BIC) analysis to human iEEG data to characterize non-linear frequency interactions in the human epileptic brain. Bicoherence changes were most prominent in the gamma (30-80 Hz) frequency band, and allowed for the differentiation between seizure and non-seizure states in all patients studied (n=3). While gamma band BIC values increased during seizure activity, this trend was only observed in a select number of electrode(s) located on the implanted patient subdural grids. Several studies have suggested that fast frequencies may play a role in the process of seizure genesis. While the small patient numbers limit the significance of our study, our results highlight the bicoherence of the gamma frequency band (30-80 Hz) as an ictal identifier, and suggest an active role of this fast frequency during seizures.

关键词： Epilepsy Oscillators Couplings Electrodes Wavelet transforms Eigenvalues and eigenfunctions Wavelet analysis

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Flor Revisited(Again):eQTL and Mutational Analysis of NB-LRR Mediated Immunity to Powdery Mildew in Barley

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Journal of Integrative Agriculture 2014年第2期13卷 237-243页

作者： Roger Wise Priyanka Surana Greg Fuerst Ruo Xu Divya Mistry Julie Dickerson Dan Nettleton Corn Insects and Crop Genetics Research Unit U.S.Department of Agriculture-Agricultural Research ServiceIowa State UniversityAmesIowa 50011USA Department of Plant Pathology & Microbiology Center for Plant Responses to Environmental StressesIowa State UniversityAmesIowa 50011USA Bioinformatics and Computational Biology Graduate Program Iowa State UniversityAmesIowa 50011USA Department of Statistics Iowa State UniversityAmesIowa 50011USA Department of Electrical and Computer Engineering Iowa State UniversityAmesIowa 50011USA

Genes encoding early signaling events in pathogen defense often are identified only by their phenotype. Such genes involved in barley-powdery mildew interactions include Mla, specifying race-specific resistance; Rarl （Required for Mla12-specified resistance1）, and Roml （Restoration of Mla-specified resistancel）. The HSP90-SGT1-RAR1 complex appears to function as chaperone in MLA-specified resistance, however, much remains to be discovered regarding the precise signaling underlying plant immunity. Genetic analyses of fast-neutron mutants derived from CI 16151 （Mla6） uncovered a novel locus, designated Rar3 （R_equired for Mla6-specified resitance3）. Rar3 segregates independent of Mla6 and Rarl, and rar3 mutants are susceptible to Blumeria graminis f. sp. hordei （Bgh） isolate 5874 （A VRar）, whereas, wild-type progenitor plants are resistant. Comparative expression analyses of the rar3 mutant vs. its wild-type progenitor were conducted via Barleyl GeneChip and GAIIx paired-end RNA-Seq. Whereas Rarl affects transcription of relatively few genes; Rar3 appears to influence thousands, notably in genes controlling ATP binding, catalytic activity, transcription, and phosphorylation; possibly membrane bound or in the nucleus, eQTL analysis of a segregating doubled haploid population identified over two-thousand genes as being regulated by Mla （q value/FDR=0.00001）, a subset of which are significant in Rar3 interactions. The intersection of datasets derived from mla-loss-of-function mutants, Mla-associated eQTL, and rar3-mediated transcriptome reprogramming are narrowing the focus on essential genes required for Mla-specified immunity.

关键词： eQTL transcript profiling immunity resistance signaling barley Blumeria graminis

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A compact and reconfigurable 8-channel Ultrasound Evaluation System for experimental research

A compact and reconfigurable 8-channel Ultrasound Evaluation...

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IEEE International Ultrasonics Symposium

作者： Amauri Amorin Assef Joaquim Miguel Maia Eduardo Tavares Costa Vera Lucia da Silveira Nantes Graduate School of Electrical Engineering and Applied Computer Sciences Federal University of Technology - Parana Curitiba Brazil Biomedical Engineering Department of the School of Electrical and Computing Engineering State University of Campinas Campinas Brazil Universidade Estadual de Campinas Campinas SP BR

Although new ultrasound (US) signal processing techniques can be designed and evaluated from simulations tools or adapting commercial clinical scanners with research interfaces, the development of novel applications also may require the development of dedicated electronic systems for research purposes. There is a need for open and cost-effective US architectures with more flexibility to enable students and researchers to reprogram and reconfigure the transmission (Tx) and reception (Rx) modules. In this paper, we present a compact and reconfigurable 8-channel FPGA and PC-based Ultrasound Evaluation System (UES) suitable for pulse-echo experiments using high-level commercial modules and specialized integrated circuits. The Tx module can excite 8 channels independently with programmable multilevel arbitrary waveforms. The Rx segment can handle simultaneously the acquisition of 8 channels with sampling rate up to 50 MHz and 12-bit resolution. The preliminary results show that the proposed system can aid researchers to develop and evaluate novel US applications and can be used as an educational tool in biomedical engineering courses.

关键词： Ultrasonic imaging Field programmable gate arrays Radio frequency Acoustics Transducers Frequency control Educational institutions

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Characterization of HFOs in short and long duration discharges recorded from in-vivo Mecp2-Deficient Mice

Characterization of HFOs in short and long duration discharg...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Sinisa Colic Min Lang Robert G. Wither Zhang Liang James H. Eubanks Berj L. Bardakjian Department of Electrical and Computer Engineering University of Toronto Division of Genetics and Development University of Toronto Epilepsy Research Program University of Toronto Department of Physiology University of Toronto Division of Fundamental Neurology Department of Medicine and University of Toronto Epilepsy Research Program University of Toronto Division of Genetics and Development Department of Surgery and University of Toronto Epilepsy Research Program University of Toronto Department of Electrical and Computer Engineering and Institute of Biomaterials and Biomedical Engineering University of Toronto

ISBN: (纸本)9781424479276

Mutations in the X-linked gene encoding methyl CpG-binding protein 2 (MeCP2) have been linked to a neurodevelopmental disorder known as Rett syndrome. The disorder is associated with a number of symptoms, of which epileptic seizures are common. In this study we examined the presence of high frequency oscillations (HFOs) and their interactions with low frequency oscillations (LFOs) during epileptiform-like discharges using intracranial electroencephalogram (iEEG) recordings from male and female Mecp2-deficient mice. The study compared differences in mean HFO power levels normalized to baseline along with LFO-HFO modulation observed in short and long duration discharges. Short duration discharges, common to both male and female Mecp2-deficient mice, showed a decrease in mean HFO power levels compared to baseline levels. During the short duration discharges the theta (7-9 Hz) LFOs were found to modulate fast ripple (350-500 Hz) HFOs predominantly in the female Mecp2-deficient mice. Long duration discharges, predominantly observed in male Mecp2-deficient mice, were found to have elevated mean power levels in the ripple (80-200 Hz) and fast ripple (350-500 Hz) frequency ranges when compared to baseline. During the long duration discharges a lower frequency range theta LFO (4-6 Hz) modulated both the ripple (80-200 Hz) and fast ripple (350-500 Hz) HFOs. These findings suggest that the long duration discharges observed in male Mecp2-deficient mice share biomarkers indicative of seizure-like activity.

关键词： Discharges (electric) Mice Hafnium oxide Frequency modulation Oscillators

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Measurement of acoustic parameters of single cell by ultrasound microscope

Transactions of Japanese Society for Medical and Biological ...

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Transactions of Japanese Society for Medical and Biological engineering 2014年 52卷 O-341-O-342页

作者： Yoshida, Koki Abuhabsah, Rami Pawlicki, Alexander D. Shikama, Joe Nagaoka, Ryo Kobayashi, Kazuto Saijo, Yoshifumi O'Brien, William D. Biomedical Imaging Laboratory Graduate School of l Engineering Tohoku University Japan Bioacoustics Research Laboratory Department of Electrical and Computer Engineering University of Illinois at Urbana-Champaign United States Division of Research and Development Honda Electronics Co. Ltd. Japan

Recently, the biomechanics of cell has received attention because the study on the biomechanics will lead to development of diagnosis and treatment of cancer and arteriosclerosis. Most methods on the measurement of biomechanics require direct contact to the cell. Because the square of sound speed is proportional to the cell elasticity, non-contact measurement of sound speed with ultrasound microscopy can obtain the mechanical properties. In the present study, quantitative measurement of cell parameters such as thickness, sound speed, acoustic impedance, density, bulk modulus, attenuation and images of each parameter are successfully obtained. The transducer had 150 MHz center frequency and f-number of 0.88 and focal length of 3.8 mm. Pulse spectrum analysis was applied to calculate thickness and sound speed of the cells because the signal from a cell surface was not distinguished from the echo from the petri dish. This study may contribute measurement of cellular biomechanics. © 2014, Japan Soc. of Med. Electronics and Biol. engineering. All rights reserved.

关键词： Biomechanics

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Investigation on Dynamic Voltage Restorers With Two DC-Links and Series Converters for Three-Phase Four-Wire Systems

Investigation on Dynamic Voltage Restorers With Two DC-Links...

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IEEE Energy Conversion Congress and Exposition

作者： Gregory A. A. Carlos Cursino B. Jacobina Euzeli C. dos Santos Department of Control and Industrial Process Federal Institute of Alagoas (IFAL) Palmeira dos Indios - 57601-220 - Alagoas - Brazil Post-Graduate Program in Electrical Engineering - PPgEE - Copele Department of Electrical Engineering Federal University of Campina Grande (UFCG) Campina Grande - 58429-900 - Paraiba - Brazil Department of Electrical and Computer Engineering Purdue School of Engineering and Technology (IUPI) Indianapolis - 46202-5160 - Indiana - USA

ISBN: (纸本)9781479957774

This paper proposes three dynamic voltage restorer (DVR) topologies. Such configurations are able to compensate voltage sags/swells in three-phase four-wire (3P4W) systems under balanced and unbalanced conditions. The proposed systems in this work use two independent dc-links. The complete control system, including the PWM technique, is developed and comparisons between the proposed configurations and a conventional one are performed. Simulation and experimental results are provided to validate the theoretical approach.

关键词： Vectors Topology Pulse width modulation Switches Inverters Capacitors Insulated gate bipolar transistors

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Transgenetic Algorithms for the Multi-objective Quadratic Assignment Problem

Transgenetic Algorithms for the Multi-objective Quadratic As...

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Brazilian Conference on Intelligent Systems (BRACIS)

作者： Carolina Paula de Almeida Richard Aderbal Gonçalves Elizabeth Ferreira Goldbarg Marco Cesar Goldbarg Myriam Regattieri Delgado Computer Science Department-UNICENTRO Guarapuava PR Brazil Federal University of Rio Grande do Norte Natal RN Brazil Graduate Program in Electrical and Computer Engineering Federal University of Parana Curitiba PR Brazil

The multi-objective Quadratic Assignment Problem (mQAP) is a hard optimization problem with many real-world applications, such as in hospital layouts. The main purposes of this paper are: (1) the investigation of hybrid algorithms combining Transgenetic Algorithms and Evolutionary Multi-objective Optimization (EMO) frameworks to deal with mQAP and (2) to compare the ability of EMO algorithms based on Pareto dominance with those based on decomposition to deal with the mQAP. Transgenetic Algorithms (TAs) are evolutionary algorithms based on cooperation as the main evolutionary strategy. Two hybrid algorithms are proposed to deal with the mQAP: NSTA (TA + NSGA-II) and MOTA/D (TA + MOEA/D). To analyze the performance of the proposed algorithms, non-parametric statistical tests and multi-objective quality indicators are used. The proposed algorithms are compared with NSGA-II and MOEA/D in 126 instances of the mQAP. The results demonstrate the superiority of decomposition and transgenetic based algorithms, particularly in MOTA/D.

关键词： Biological cells Vectors Sociology Statistics Sorting Optimization Algorithm design and analysis

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Corrigendum to "Target-specific near-IR induced drug release and photothermal therapy with accumulated Au/Ag hollow nanoshells on pulmonary cancer cell membranes" [Biomaterials 45 (2015) 81-92]

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Biomaterials 2015年 65卷 124-125页

作者： Mi Suk Noh Somin Lee Homan Kang Jin-Kyoung Yang Hyunmi Lee Doyk Hwang Jong Woo Lee Sinyoung Jeong Yoonjeong Jang Bong-Hyun Jun Dae Hong Jeong Seong Keun Kim Yoon-Sik Lee Myung-Haing Cho Laboratory of Toxicology College of Veterinary Medicine Seoul National University Seoul 151-742 Republic of Korea Program in Nano Science and Technology Graduate School of Convergence Science and Technology Seoul National University Seoul 151-742 Republic of Korea Medical Supplies Evaluation Center Korea Testing Certification Gunpo 435-862 Republic of Korea. Graduate Group of Tumor Biology Seoul National University Seoul 151-742 Republic of Korea. Interdisciplinary Program in Nano-Science and Technology Seoul National University Seoul 151-742 Republic of Korea School of Electrical Engineering and Computer Science Seoul National University Seoul 151-742 Republic of Korea. School of Chemical and Biological Engineering Seoul National University Seoul 151-742 Republic of Korea. Department of Biophysics and Chemical Biology and Department of Chemistry Seoul National University Seoul 151-742 Republic of Korea. Department of Chemistry Education Seoul National University Seoul 151-742 Republic of Korea. Laboratory of Toxicology College of Veterinary Medicine Seoul National University Seoul 151-742 Republic of Korea. Department of Bioscience and Biotechnology Konkuk University Seoul 143-701 Republic of Korea. Department of Chemistry Education Seoul National University Seoul 151-742 Republic of Korea. School of Chemical and Biological Engineering Seoul National University Seoul 151-742 Republic of Korea. Electronic address: yslee@snu.ac.kr. Graduate Group of Tumor Biology Seoul National University Seoul 151-742 Republic of Korea Advanced Institute of Convergence Technology Seoul National University Suwon 443-270 Republic of Korea. Electronic address: mchotox@snu.ac.kr.

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SAPF with two Dc-links and series converters feeding OEW transformers for 3P4W systems

SAPF with two Dc-links and series converters feeding OEW tra...

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Annual Conference of Industrial Electronics Society

作者： Gregory A. de A. Carlos Cursino B. Jacobina Euzeli C. dos Santos Department of Control and Industrial Process Federal Institute of Alagoas (IFAL) Palmeira dos Índios - 57601-220 - Alagoas - Brazil Post-Graduate Program in Electrical Engineering - PPgEE - Copele Federal University of Campina Grande (UFCG) Campina Grande Paraíba Brazil Department of Electrical and Computer Engineering Purdue School of Engineering and Technology (IUPUI) Indiana USA

This paper presents a shunt active power filter (SAPF) topology, based on the concept of a transformer with open-end winding (OEW), for reactive power and harmonic compensations employed in three-phase four wire (3P4W) systems under balanced and unbalanced conditions. The proposed system uses two independent dc-links and two independent converters series connected through transformers. Complete system control, including PWM technique, is developed and a comparison between the proposed SAPF and conventional one is presented as well. Simulation and experimental results are provided to validate the theoretical approach.

关键词： Topology Pulse width modulation Capacitors Voltage control Optimization Harmonic analysis Power system harmonics

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