Obstructive sleep apnea (OSA) is a common sleep disorder that affects 1–5 % of children, with a notably higher prevalence among those with cleft lip/palate and dentofacial deformities. Early diagnosis in these popula...
Obstructive sleep apnea (OSA) is a common sleep disorder that affects 1–5 % of children, with a notably higher prevalence among those with cleft lip/palate and dentofacial deformities. Early diagnosis in these populations is essential; however, access to polysomnography is often limited due to its high cost, technical complexity, and associated discomfort. Here, we introduce a wireless, soft, and breathable bioelectronic system for detecting OSA. This wearable device features a perforated, deformable structure that improves skin conformity, facilitates sweat removal, and minimizes motion artifacts. By measuring electrophysiological signals on the face, the system employs a deep learning framework that integrates multi-stream convolutional neural networks with bi-directional long short-term memory models to classify sleep stages and detect apnea events automatically. This work establishes a foundation for the diagnosis of pediatric OSA and has the potential to differentiate pre- and post-operative sleep patterns in patients undergoing orthognathic surgery.
Carbon fixation is the main route of inorganic carbon in the form of CO2 into the *** nature,RuBisCO is the most abundant protein that photosynthetic organisms use to fix CO2 from the atmosphere through the Calvin-Ben...
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Carbon fixation is the main route of inorganic carbon in the form of CO2 into the *** nature,RuBisCO is the most abundant protein that photosynthetic organisms use to fix CO2 from the atmosphere through the Calvin-Benson-Bassham(CBB)***,the CBB cycle is limited by its low catalytic rate and low energy *** this work,we attempt to integrate the reductive tricarboxylic acid and CBB cycles in silico to further improve carbon fixation *** heterologous enzymes,mostly carboxylating enzymes,are inserted into the Esherichia coli core metabolic network to assimilate CO2 into biomass using hydrogen as energy ***,such a strain shows enhanced growth yield with simultaneous running of dual carbon fixation *** key results include the following.(i)We identified two main growth states:carbon-limited and hydrogenlimited;(ii)we identified a hierarchy of carbon fixation usage when hydrogen supply is limited;and(iii)we identified the alternative sub-optimal growth mode while performing genetic *** results and modeling approach can guide bioengineering projects toward optimal production using such a strain as a microbial cell factory.
Starting from Gauss and Kelvin, knots in fields were postulated behaving like particles, but experimentally they were found only as transient features or required complex boundary conditions to exist and couldn’t sel...
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Coexistence of order and fluidity in soft matter often mimics that in biology, allowing for complex dynamics and applications like displays. In active soft matter, emergent order can arise because of such dynamics. Po...
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Chiral condensed matter systems, such as liquid crystals and magnets, exhibit a host of spatially localized topological structures that emerge from the medium’s tendency to twist and its competition with confinement ...
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Topological solitons, such as skyrmions, arise in field theories of systems ranging from Bose-Einstein condensates to optics, particle physics, and cosmology, but they are rarely accessible experimentally. Chiral nema...
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Light provides a powerful means of controlling physical behavior of materials but is rarely used to power and guide active matter systems. We demonstrate optical control of liquid crystalline topological solitons dubb...
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Highly-directional image artifacts such as ion mill curtaining, mechanical scratches, or image striping from beam instability degrade the interpretability of micrographs. These unwanted, aperiodic features extend the ...
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Organisch‐anorganische Hybridmaterialien gelten als neue Kandidaten auf dem Gebiet der thermoelektrischen Materialien. Sie haben ein großes Potenzial, die thermoelektrische Leistung zu verbessern, indem die nied...
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Organisch‐anorganische Hybridmaterialien gelten als neue Kandidaten auf dem Gebiet der thermoelektrischen Materialien. Sie haben ein großes Potenzial, die thermoelektrische Leistung zu verbessern, indem die niedrige Wärmeleitfähigkeit organischer Materialien einerseits sowie der hohe Seebeck‐Koeffizient und die hohe elektrische Leitfähigkeit anorganischer Materialien andererseits genutzt werden. In diesem Aufsatz soll ein Überblick über das Grenzflächen‐engineering in der Synthese verschiedener organisch‐anorganischer thermoelektrischer Hybridmaterialien sowie über die dimensionale Gestaltung zur Optimierung ihrer thermoelektrischen Eigenschaften gegeben werden. Die Grenzflächeneffekte werden hinsichtlich Nanostrukturen, physikalischer Eigenschaften und chemischer Dotierung zwischen anorganischen und organischen Komponenten betrachtet. Einige Schlüsselfaktoren, die die thermoelektrische Effizienz und Leistung elektronischer Bauelemente bestimmen, werden ebenso diskutiert wie die Wärmeleitfähigkeit, der elektrische Transport, die elektronischen Bandstrukturen und die Bandkonvergenz der Hybridmaterialien.
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