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High-yield and rapid isolation of extracellular vesicles by flocculation via orbital acoustic trapping:FLOAT

Microsystems & Nanoengineering 2024年第1期10卷 313-323页

作者： Joseph Rufo Peiran Zhang Zeyu Wang Yuyang Gu Kaichun Yang Joseph Rich Chuyi Chen Ruoyu Zhong Ke Jin Ye He Jianping Xia Ke Li Jiarong Wu Yingshi Ouyang Yoel Sadovsky Luke P.Lee Tony Jun Huang Department of Mechanical Engineering and Materials Science Duke UniversityDurhamNCUSA Department of Biomedical Engineering Duke UniversityDurhamNCUSA Department of Obstetrics Gynecologyand Reproductive SciencesMagee-Womens Research InstituteUniversity of PittsburghPittsburghPAUSA Department of Microbiology and Molecular Genetics School of MedicineUniversity of PittsburghPittsburghPAUSA Renal Division and Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMAUSA Department of Bioengineering Department of Electrical Engineering and Computer ScienceUniversity of CaliforniaBerkeleyBerkeleyCAUSA Department of Biophysics Institute of Quantum BiophysicsSungkyunkwan UniversitySuwonKorea

Extracellular vesicles(EVs)have been identified as promising biomarkers for the noninvasive diagnosis of various ***,challenges in separating EVs from soluble proteins have resulted in variable EV recovery rates and low ***,we report a high-yield(>90%)and rapid(<10 min)EV isolation method called FLocculation via Orbital Acoustic Trapping(FLOAT).The FLOAT approach utilizes an acoustofluidic droplet centrifuge to rotate and controllably heat liquid *** adding a thermoresponsive polymer flocculant,nanoparticles as small as 20 nm can be rapidly and selectively concentrated at the center of the *** demonstrate the ability of FLOAT to separate urinary EVs from the highly abundant Tamm-Horsfall protein,addressing a significant obstacle in the development of EV-based liquid *** to its high-yield nature,FLOAT reduces biofluid starting volume requirements by a factor of 100(from 20 mL to 200µL),demonstrating its promising potential in point-of-care diagnostics.

关键词： trapping utilize separating

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Au/SiC Microfluidic Devices Fabricated by Rapid Laser Cladding for Photocatalytic Degradation of Water Pollutants

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ACS Sustainable Chemistry and engineering 2024年第11期12卷 4486-4496页

作者： Chang, Chun-Hao Lin, Hsiu-Pen Chen, Chien-Wei Lu, Yu-Cheng Hsiao, Fu-He Hsieh, Chi-Hsiang Lin, Bo-Cheng Yu, Bang-Ying Ma, Dai-Liang Kuo, Hao-Chung Tu, Chang-Ching Li, Bor-Ran Institute of Biomedical Engineering College of Electrical and Computer Engineering National Yang Ming Chiao Tung University Hsinchu300093 Taiwan Department of Electrical and Computer Engineering College of Electrical and Computer Engineering National Yang Ming Chiao Tung University Hsinchu300093 Taiwan Centre for Emergent Functional Matter Science National Yang Ming Chiao Tung University Hsinchu300093 Taiwan Department of Electrophysics College of Science National Yang Ming Chiao Tung University Hsinchu300093 Taiwan Semiconductor Research Center Hon Hai Research Institute Taipei11492 Taiwan Department of Photonics Institute of Electro-Optical Engineering College of Electrical and Computer Engineering National Yang Ming Chiao Tung University Hsinchu300093 Taiwan Taisic Materials Corp. Taoyuan320 Taiwan Department of Electrical Engineering National Central University Taoyuan32001 Taiwan Medical Device Innovation and Translation R&D Center National Yang Ming Chiao Tung University Taipei112304 Taiwan

The increasing proliferation of third-generation semiconductor silicon carbide (SiC) products has led to the emergence of SiC powder as an industrial byproduct. To reutilize the SiC efficiently, we propose a facile method for fabrication of photocatalytic plates from reclaimed SiC. Our approach involves affixing the SiC onto a glass surface with laser cladding, followed by sputter deposition of a gold film and laser annealing. The resulting nanogold-coated SiC plate exhibited enhanced photocatalytic activity due to the injection of hot electrons into the SiC via surface plasmon resonance. Unlike chemical reduction, which requires hours for the synthesis, purification, and isolation of Au/SiC, our approach accomplished this in just 30 min. When illuminated, the Au/SiC plate generated electron-hole pairs that formed radicals in the presence of water and oxygen, leading to the decomposition of methylene blue. Furthermore, the Au/SiC plate can be integrated into a microfluidic device for an enhanced degradation rate and efficiency. This research provides a simple and environmentally friendly approach to the production of photocatalytic plates from reclaimed SiC and contributes to sustainable development. © 2024 The Authors. Published by American Chemical Society.

关键词： Silicon carbide

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Enhancing supply chain security through laser-fabricated marks on stainless steel 19

Enhancing supply chain security through laser-fabricated mar...

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Laser-based Micro- and Nanoprocessing XIX 2025

作者： Tselios, Christos Mazzucato, Simone Politi, Christina Alexandropoulos, Dimitris Department of Electrical and Computer Engineering University of Patras Achaia Patras26504 Greece Department of Electrical and Computer Engineering University of Peloponnese Achaia Patras22100 Greece SISMA S.p.A. via dell’Industria 1 Piovene Rocchette VI36013 Italy Department of Materials Science University of Patras Achaia Patras26504 Greece

ISBN: (纸本)9781510684508

We present a novel method for generating cryptographic keys from laser-engraved holograms on stainless steel, designed to enhance supply chain security with a focus on industrial scalability, ease of verification, and compliance with National Institute of Standards and Technology (NIST) standards. Using laser-writing technology and off-the-shelf components for key extraction, our approach provides a straightforward, cost-effective, and reliable authentication mechanism between manufacturers and end users. By applying image processing and randomness extraction algorithms, we generate 16-kbit cryptographic keys from each engraving. To validate the effectiveness of these laser-fabricated marks, we analyze correlation coefficient maps and Hamming distance distributions between key sequences from different engravings, demonstrating minimal similarity and enhanced security. Furthermore, the generated 160-kbit key sequences successfully passed all statistical tests of the NIST SP 800-22 test suite. This method offers a practical and scalable solution for anti-counterfeiting and security in real-world applications. © 2025 SPIE.

关键词： Holograms

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Toward Safe and Efficient Human-Robot Interaction via Behavior-Driven Danger Signaling

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IEEE Transactions on Control Systems Technology 2024年第1期32卷 214-224页

作者： Hosseinzadeh, Mehdi Sinopoli, Bruno Bobick, Aaron F. Washington State University School of Mechanical and Materials Engineering PullmanWA99164 United States Washington University in St. Louis Department of Electrical and Systems Engineering St. LouisMO63130 United States Washington University in St. Louis Department of Computer Science and Engineering St. LouisMO63130 United States

This article introduces the notion of danger awareness in the context of human-robot interaction, which decodes whether a human is aware of the existence of the robot, and illuminates whether the human is willing to engage in ensuring safety. This article also quantifies the notion as a single binary variable, called danger awareness coefficient, and provides a game-theoretic interpretation for that. Employing an online Bayesian learning method to update the robot's belief about the human's danger awareness by observing their actions, it is shown how the robot can build a predictive human model to anticipate the human's future actions. To enrich robot's observations, and thus to improve safety and efficiency of the robot, the robot is equipped with a danger signaling system to generate awareness in the human. Finally, a planning scheme is proposed to provide an efficient and probabilistically safe plan for the robot. The effectiveness of the proposed scheme is demonstrated through simulation studies on an interaction between a self-driven car and a pedestrian. © 1993-2012 IEEE.

关键词： Human robot interaction

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High bandwidth semipolar (20-21) micro-LED-based white light-emitting diodes utilizing perovskite quantum dots and organic emitters in color-conversion layers for visible light communication and solid-state lighting applications

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Nanoscale 2023年第17期15卷 7715-7721页

作者： Sadhu, Annada Sankar Pai, Yi-Hua Chen, Li-Yin Hsieh, Chung-An Lin, Hao-Wu Kuo, Hao-Chung Department of Photonics Institute of Electro-Optical Engineering College of Electrical and Computer Engineering National Yang Ming Chiao Tung University Hsinchu30010 Taiwan College of Electrical and Computer Engineering National Yang Ming Chiao Tung University Hsinchu30010 Taiwan Department of Materials Science and Engineering National Tsing Hua University Hsinchu30013 Taiwan Semiconductor Research Center Hon Hai Research Institute Taipei11492 Taiwan

We demonstrate semipolar (20-21) micro-LED-based high-bandwidth WLEDs utilizing perovskite QDs and organic emitters in color-conversion films. The WLEDs exhibit a bandwidth in excess of 1 GHz and a CCT of 6141 K, making these devices suitable for visible light communication and lighting applications. © 2023 The Royal Society of Chemistry.

关键词： Perovskite

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Understanding the stability of advanced inorganic-organic hybrid thin films for advanced resist applications 41

Understanding the stability of advanced inorganic-organic hy...

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Advances in Patterning materials and Processes XLI 2024

作者： Le, Dan N. Chu, Thi Thu Huong Kim, Jin-Hyun Veyan, Jean-Francois Lee, Won-Il Tiwale, Nikhil Lee, Minjong Choi, Seungsoo Woo, Jihoon Nam, Chang-Yong Choi, Rino Kim, Jiyoung Department of Materials Science and Engineering University of Texas at Dallas RichardsonTX75080 United States Department of Materials Science and Chemical Engineering Stony Brook University Stony BrookNY11794 United States Center for Functional Nanomaterials Brookhaven National Laboratory UptonNY11973 United States Department of Electrical and Computer Engineering University of Texas at Dallas RichardsonTX75080 United States Program in Enviromental and Polymer Engineering Inha University Incheon22212 Korea Republic of Department of Materials Science and Engineering Inha University Incheon22212 Korea Republic of

ISBN: (纸本)9781510672208

In this study, we focus on examining the stability of Al-based inorganic-organic hybrid thin films deposited through the molecular atomic layer deposition (MALD) process in ambient environment. Our observations reveal an initial reduction in material thickness within the first 3 days, followed by a period of stability. XPS analysis is employed to further investigate the chemical alternations in the aged Al-based hybrid thin films, revealing an increase in C=O species as well as overall oxygen content in the material. We also evaluate the effects of atmospheric exposure on the sensitivity of the Al-based hybrid thin films using electron flood exposure. This study aims to enhance the understanding of the stability of a vapor-phase synthesized hybrid thin film system for advanced resist applications. © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

关键词： Atomic layer deposition

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Two-Electrode Screen-Printed pH Sensors for Monitoring Soil and Other Growing Media

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IEEE Sensors Journal 2025年第11期25卷 18692-18701页

作者： Crichton, Catherine A. Lahann, Lucas Barba, Juan Pablo Cisneros Yuan, Titan Strand, Elliot J. Bruno, Nicholas Goodrich, Payton J. Baumbauer, Carol L. Atreya, Madhur Bihar, Eloise Silver, Whendee L. Pister, Kristofer Arias, Ana Claudia Whiting, Gregory L. University of California Berkeley Department of Electrical Engineering and Computer Science 253 Cory Hall BerkeleyCA94720 United States University of California Berkeley Department of Environmental Science Policy and Management 130 Mulford Hall BerkeleyCA94720 United States University of Colorado Boulder Paul M. Rady Department of Mechanical Engineering 1111 Engineering Drive BoulderCO80309 United States University of Colorado Boulder Materials Science and Engineering 4001 Discovery Drive BoulderCO80303 United States

Monitoring soil pH is important for optimizing plant biomass production, understanding nutrient cycling, predicting and mitigating greenhouse gas emissions, and improving soil health. Soil pH can vary significantly over time and space, and high spatiotemporal resolution data are needed to enable informed land management decisions. A potential method to address this need is to use large numbers of easily distributed pH sensor systems which can be placed at high density in soils. An approach for fabricating such sensors is described here using a voltammetric screen-printed pH sensor with a working electrode that incorporates Alizarin (a pH-sensitive dye) throughout its bulk. The use of a Nafion membrane on top of the working electrode and a salt membrane over the reference electrode provides near-Nernstian sensitivity and enhanced device stability in buffered media, soil, and hydroponic fluid. Critically, these devices can function effectively in a novel 2-electrode (working and reference) configuration with a sensitivity of 56.38 mV/pH and a resolution of 0.28 pH (n=3), enabling the use of simple, low-cost readout electronics for evaluating the sensor state. These results show that a printed pH sensor paired with affordable electronics can be used to monitor the pH of unbuffered media, providing a potential path to high-spatial density real-time measurement of pH in soils and hydroponics. © 2001-2012 IEEE.

关键词： Alizarin

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VLC-enabled UAV Network for IoT with Co-channel Interference: Joint Spatial Deployment and Resource Allocation

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IEEE Internet of Things Journal 2025年第12期12卷 20707-20721页

作者： Liu, Jiaji Yang, Fang An, Nan Song, Jian Han, Zhu State Key Laboratory of Widegap Semiconductor Optoelectronic Materials and Technologies Beijing100084 China Tsinghua University Beijing National Research Center for Information Science and Technology Department of Electronic Engineering Beijing100084 China Research Institute of Tsinghua University Shenzhen518057 China Tsinghua University Shenzhen International Graduate School Shenzhen518055 China University of Houston Department of Electrical and Computer Engineering HoustonTX77004 United States Kyung Hee University Department of Computer Science and Engineering Seoul446-701 Korea Republic of

Unmanned aerial vehicles (UAVs) have gained significant attention due to their low cost and efficient deployment. Specifically, UAV-based communications hold promise to supplement the coverage limitations of terrestrial networks and achieve superior connectivity for the Internet of Things (IoT). Moreover, UAVs with visible light communication (VLC) capability do not interfere with existing radio frequency (RF) communication infrastructure, thereby providing flexible, high-throughput on-demand wireless communications. In this paper, considering the limited battery capacity of UAVs, we aim to maximize the energy efficiency (EE) of a multi-UAV downlink VLC system for IoT. To this end, the system model with co-channel interference is first established, followed by the formulation of the joint spatial deployment and resource allocation problem. Besides, the original problem is decomposed into three subproblems, focusing on spatial deployment, subchannel assignment, and power allocation. By employing the block coordinate descent method, the three subproblems are solved alternately. Moreover, simulation results demonstrate that the proposed method achieves superior improvements in EE compared to other baselines. In addition, the convergence and computational complexity of the proposed algorithm, as well as the impacts of key parameters on the overall system performance are also investigated. © 2025 IEEE.

关键词： Unmanned aerial vehicles (UAV)

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High piezoelectricity after field cooling AC poling in temperature stable ternary single crystals manufactured by continuous-feeding Bridgman method

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Journal of Advanced Ceramics 2022年第1期11卷 57-65页

作者： Cong LUO Tomoaki KARAKI Zhuangkai WANG Yiqin SUN Yohachi(John)YAMASHITA Jiayue XU School of Materials Science and Engineering Shanghai Institute of TechnologyShanghai 201418China Department of Electrical and Computer Engineering Faculty of EngineeringToyama Prefectural UniversityToyama 939-0398Japan Department of Mechanical&Aerospace Engineering North Carolina State UniversityNC 27695-7910USA

After field cooling(FC)alternating current poling(ACP),we investigated the dielectric and piezoelectric properties of[001]_(pc)-oriented 0.24Pb(In_(1/2)Nb_(1/2))O_(3)(PIN)-0.46Pb(Mg_(1/3)Nb_(2/3))O_(3)(PMN)-0.30PbTiO3(PT)(PIMN-0.30PT)single crystals(SCs),which were manufactured by continuous-feeding Bridgman(CF BM)within morphotropic phase boundary(MPB)*** ACP with 4 kVrms/cm from 100 to 70℃,the PIMN-0.30PT SC attained high dielectric permittivity of 8330,piezoelectric coefficient(d_(33))of 2750 pC/N,bar mode electromechanical coupling factorκ_(33)of 0.96 with higher phase change temperature(T_(pc))of 103℃,and high Curie temperature(7c)of 180℃.These values are the highest ever reported as PIMN-xPT SC system with Tpc>100℃.The enhancement of these properties is attributed to the induced low symmetry multi-phase supported by phase *** work indicates that FC ACP is a smart and promising method to enhance piezoelectric properties of relaxor-PT ferroelectric SCs including PIMN-xPT,and provides a route to a wide range of piezoelectric device applications.

关键词： field cooling(FC)alternating current poling(ACP) PIMN-0.30PT high piezoelectricity

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Analysis and Design of Vector Holographic Metasurfaces

Analysis and Design of Vector Holographic Metasurfaces

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2024 Photonics and Electromagnetics Research Symposium, PIERS 2024

作者： Pitilakis, A. Tsilipakos, O. Tasolamprou, A.C. Tsioliaridou, A. Kantartzis, N.V. Ioannidis, S. Liaskos, C. Kafesaki, M. Institute of Electronic Structure and Laser Foundation for Research and Technology Hellas Greece Aristotle University of Thessaloniki School of Electrical and Computer Engineering Greece Theoretical and Physical Chemistry Institute National Hellenic Research Foundation Greece National and Kapodistrian University of Athens Department of Physics Greece Institute of Computer Science Foundation for Research and Technology Hellas Greece Technical University of Crete School of Electrical & Computer Engineering Greece University of Ioannina Department of Computer Science and Engineering Greece University of Crete Department of Materials Science and Technology Greece

ISBN: (纸本)9798350375909

In this work we present a comprehensive framework for the analysis and design of vector holographic metasurfaces (VHMS). The term vector refers to the metasurface ability to manipulate the polarization of the scattered wave, while holographic refers to the configuration of the metasurface aperture, which can have any arbitrary complex profile in its equivalent surface impedance (phase and/or magnitude). We start from the presentation of the analysis of such VHMS, i.e., the calculation of its scattering under given equivalent surface impedance configuration and illumination;the analysis relies on physical optics and can, in theory, model the scattering and diffraction by a finite-aperture metasurface of arbitrary convex shape under arbitrary spatially coherent wavefront illumination. We then present the VHMS design and synthesis procedure, i.e., we compute its equivalent and physical configuration, when given the illuminating wavefront and the desired scattering response or functionality, e.g., beam steering or focusing. For the synthesis, we use a simple scalable unit cell topology incorporating square conductor patches interconnected with lumped complex loads;these can locally and continuously tune the VHMS phase and amplitude response, with independent control over both polarizations, thus allowing arbitrary incident-to-scattered wavefront transformations. These versatile devices, especially when fused with wavefront sensing capabilities, can be used in applications spanning wireless communications (e.g., beamforming, integrated/joint sensing and communication, or programmable wireless environments), radar scattering (e.g., stealth), and holography/imaging. © 2024 IEEE.

关键词： Wavefronts

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