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Tumor treating fields (TTFs) are a novel electric field-based cancer treatment modality for solid tumors. On the other hand, integrated capacitance sensing is a lab-on-a-chip technology that provides quantitative meas...
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The global energy environment is shifting toward sustainability and carbon neutrality. Internet of Things (IoT) technology with Carbon Capture and Storage (CCS) in Enhanced Oil Recovery (EOR) may reduce carbon emissio...
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Integrating solar PV inverters and storage devices into the modern power grid generates multiple power profiles with varying magnitudes. The intermittent nature of PV necessitates installing storage devices to reduce ...
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Decoding neural signatures of visuo-spatial functions can play an important role in guiding human-computer interactions (HCI). Virtual reality (VR) enhances these interactions and offers a new tool for exploring visuo...
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We propose a novel intensity diffraction tomography reconstruction algorithm based on the split-step non-paraxial model for recovering the 3D refractive index distribution of multiple-scattering biological samples. ...
Medical ultrasound is utilized as the primary method for the detection of kidney stones. Ultrasound imaging is often more popular than other imaging techniques because it is portable, low-cost, non-invasive, and does ...
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Coherence-based ultrasound imaging has demonstrated potential to improve breast mass diagnosis by distinguishing solid from fluid-filled masses. Harmonic imaging, which is known to reduce acoustic clutter, has the pot...
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ISBN:
(纸本)9781510660311
Coherence-based ultrasound imaging has demonstrated potential to improve breast mass diagnosis by distinguishing solid from fluid-filled masses. Harmonic imaging, which is known to reduce acoustic clutter, has the potential to offer additional improvements. However, the lack of a theoretical basis to describe these improvements precludes clinical recommendations based on physics and engineering principles. This work is the first to develop a theoretical model of coherence-based ultrasound imaging to describe both solid vs. fluid mass distinction and the effects of harmonic short-lag spatial coherence (SLSC) imaging. The scattering function and the transmit ultrasound beam of the van Cittert-Zernike theorem applied to ultrasound imaging were redefined to generate the theoretical model for solid vs. fluid mass distinction and for harmonic imaging, respectively. The derived theory was used to compare fundamental and harmonic SLSC images for hypoechoic solid, hypoechoic fluid, hyperechoic, and point targets. Theoretical simulations showed improved resolution, mitigated dark-region artifacts around hyperechoic targets, and increased spatial coherence of fluid masses in harmonic SLSC images when compared to fundamental SLSC images. Experimental data from tissue-mimicking phantoms and in vivo breast ultrasound images agreed with theoretical results. In particular, when compared to fundamental SLSC imaging, harmonic SLSC imaging improved resolution by 0.19 ± 0.25 mm, mitigated dark region artifacts by 0.55 ± 0.54 mm, and increased the spatial coherence of fluid-filled masses, resulting in a 6.50 ± 4.28 dB decrease in contrast. Results will enable future clinical recommendations supporting the use of fundamental or harmonic SLSC imaging for analyses of fluid or solid masses, respectively. These contributions establish a theoretical foundation to combine fundamental and harmonic coherence-based imaging with harmonic B-mode imaging to improve the accuracy of breast mass diagno
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