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Correction: Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a randomized controlled trial

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Immunity & ageing : I & A 2022年第1期19卷 30页

作者： Grace M Niemiro Adriana M Coletta Nadia H Agha Preteesh Leo Mylabathula Forrest L Baker Abenaa M Brewster Therese B Bevers Enrique Fuentes-Mattei Karen Basen-Engquist Emmanuel Katsanis Susan C Gilchrist Richard J Simpson Department of Pediatrics The University of Arizona Tucson Arizona USA. The University of Arizona Cancer Center Tucson Arizona USA. Department of Health and Kinesiology The University of Utah Salt Lake City Utah USA. Cancer Control and Population Sciences Program Huntsman Cancer Institute Salt Lake City Utah USA. Department of Health and Human Performance University of Houston Houston Texas USA. School of Nutritional Sciences and Wellness The University of Arizona Tucson Arizona USA. Department of Clinical Cancer Prevention The University of Texas MD Anderson Cancer Center Houston Texas USA. Department of Radiation Oncology Clinical Research The University of Texas MD Anderson Cancer Center Houston Texas USA. Department of Behavioral Science The University of Texas MD Anderson Cancer Center Houston Texas USA. Department of Immunobiology The University of Arizona Tucson Arizona USA. Department of Cardiology The University of Texas MD Anderson Cancer Center Houston Texas USA. Department of Pediatrics The University of Arizona Tucson Arizona USA. rjsimpson@arizona.edu. The University of Arizona Cancer Center Tucson Arizona USA. rjsimpson@arizona.edu. Department of Health and Human Performance University of Houston Houston Texas USA. rjsimpson@arizona.edu. School of Nutritional Sciences and Wellness The University of Arizona Tucson Arizona USA. rjsimpson@arizona.edu. Department of Behavioral Science The University of Texas MD Anderson Cancer Center Houston Texas USA. rjsimpson@arizona.edu. Department of Immunobiology The University of Arizona Tucson Arizona USA. rjsimpson@arizona.edu.

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Management of individuals exposed to multidrug-resistant or rifampicin-resistant tuberculosis

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The Lancet Infectious Diseases 2025年

作者： James A Seddon Jay Achar Amyn A Malik Jennifer Hughes Joseph Burzynski Cheng Chen Justin T Denholm Gunta Dravniece Greg J Fox Jennifer Furin Evgenia Geliukh Olga Goncharova Lorenzo Guglielmetti Anthony D Harries Anneke C Hesseling Binh Hoa Nguyen Fungai Kavenga Uzma Khan Yousra Kherabi Nana Kiria Leonardo Martinez Department of Infectious Disease Imperial College London London UK Desmond Tutu TB Centre Department of Paediatrics and Child Health Stellenbosch University Cape Town South Africa Department of Global Public Health Karolinska Institutet Stockholm Sweden Department for Science and Innovation—National Research Fund Centre of Excellence for Biomedical Tuberculosis Research South African Medical Research Council Centre for Tuberculosis Research Division of Molecular Biology and Human Genetics Faculty of Medicine and Health Sciences Stellenbosch University Stellenbosch South Africa O'Donnell School of Public Health UT Southwestern Medical Center Dallas TX USA Bureau of Tuberculosis Control New York City Department of Health and Mental Hygiene New York NY USA Department of Chronic Communicable Disease Center for Disease Control and Prevention of Jiangsu Province Nanjing China Victorian Tuberculosis Program Melbourne Health Melbourne VIC Australia Department of Infectious Diseases University of Melbourne Parkville VIC Australia PATH Kyiv Ukraine Faculty of Medicine and Health University of Sydney Sydney NSW Australia Department of Global Health and Social Medicine Harvard Medical School Boston MA USA Alliance for Public Health Kyiv Ukraine National Center of Phthisiology Bishkek Kyrgyzstan Centre d'Immunologie et des Maladies Infectieuses INSERM Sorbonne Université Paris France Assistance Publique Hopitaux de Paris Hopital Pitié-Salpêtrière Centre National de Reference des Mycobacteries Paris France Centre for Operational Research International Union Against Tuberculosis and Lung Disease Paris France Department of Clinical Research Faculty of Infectious and Tropical Diseases London School of Hygiene & Tropical Medicine London UK National Tuberculosis Program Hanoi Viet Nam Hanoi Medical University Hanoi Viet Nam Ministry of Health and Child Care National TB & Leprosy Control Program Harare Zimbabwe Interactive Research & Development Global Singapore

Individuals exposed to a person with infectious multidrug-resistant or rifampicin-resistant (MDR-RR) tuberculosis are at risk of developing tuberculosis disease. Historically, insufficient empirical evidence for preventive treatment in this group has permitted inadequate guidance for clinical decision making. However, several high-quality studies have been published detailing preventive treatment options for these contacts at high risk. In this Review, we discuss the management of individuals exposed to patients with infectious MDR-RR tuberculosis. We pay particular attention to the entire spectrum of clinical care for this population, including baseline assessment, possible preventive treatments, follow-up, and shared decision making. We discuss the available evidence, the rationales for different management strategies, and the interactions with (and implications of) secondary comorbidities such as HIV or malnutrition.

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880Dietary inflammatory index and the risk of adult depression symptoms

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International Journal of epidemiology 2021年第SUPPLEMENT_1期50卷

作者： Shakya, Prem Melaku, Yohannes Adama Page, Amanda J Adams, Robert J Shivappa, Nitin Hébert, James R Gill, Tiffany K Vagal Afferent Research Group University of Adelaide Adelaide Australia Nutrition Diabetes and Metabolism Lifelong Health South Australian Health and Medical Research Institute (SAHMRI) Adelaide Australia Adelaide Institute for Sleep Health (AISH) Flinders University Bedford Park Australia Adelaide Medical School University of Adelaide Adelaide Australia Cancer Prevention and Control Program University of South Carolina Columbia USA Department of Epidemiology and Biostatistics Arnold School of Public Health University of South Carolina Columbia USA

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Correction to: Human Papillomavirus and Factors Associated with Recurrence in Sinonasal Inverted Papillomas from Poland and Spain

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Head and neck pathology 2020年第3期14卷 768-770页

作者： M Fulla T Szafarowski J Frias-Gomez B Quiros O Clavero M Gomà M A Pavon O Jurek-Matusiak H R Lares M Mañós L Alemany M Mena X Gonzalez Department of Otorhinolaryngology Hospital Universitari Bellvitge L'Hospitalet de Llobregat Barcelona Spain. mfulla@bellvitgehospital.cat. Program of Molecular Mechanisms and Experimental Therapy in Oncology Bellvitge Biomedical Research Institute (IDIBELL) L'Hospitalet de Llobregat Barcelona Spain. mfulla@bellvitgehospital.cat. Department of Otorhinolaryngology Faculty of Medicine and Dentistry Medical University of Warsaw Warsaw Poland. Cancer Epidemiology Research Program Catalan Institute of Oncology (ICO) - L'Hospitalet de Llobregat Barcelona Spain. Epidemiology Public Health Cancer Prevention and Palliative Care Program IDIBELL L'Hospitalet de Llobregat Barcelona Spain. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC) Instituto de Salud Carlos III Madrid Spain. Program of Molecular Mechanisms and Experimental Therapy in Oncology Bellvitge Biomedical Research Institute (IDIBELL) L'Hospitalet de Llobregat Barcelona Spain. Department of Pathology Hospital Universitari Bellvitge L'Hospitalet de Llobregat Barcelona Spain. Department of Otorhinolaryngology Hospital Universitari Bellvitge L'Hospitalet de Llobregat Barcelona Spain. University of Barcelona Barcelona Spain. Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP) Instituto de Salud Carlos III Madrid Spain.

The original version of this article unfortunately contained a mistake. Three values in Table 1 were incorrect. In "months of recurrence", range row, the intervals should be in numbers. They should read as 3-83 instead of Mar-83, 9-83 instead of Sep-83 and 3-36 instead of Mar-36. The corrected Table 1 is given below. The original article has been corrected.

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Lifetime physical inactivity is associated with lung cancer risk and mortality

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cancer Treatment and Research Communications 2018年 14卷 37-45页

作者： Cannioto, Rikki Etter, John Lewis LaMonte, Michael J. Ray, Andrew D. Joseph, Janine M. Qassim, Emad Al Eng, Kevin H. Moysich, Kirsten B. Department of Cancer Prevention and Control Roswell Park Comprehensive Cancer Center Elm and Carlton Streets Buffalo 14263 New York United States Department of Epidemiology and Environmental Health University at Buffalo 273 Farber Hall Buffalo 14214 NY United States Department of Rehabilitation Science University at Buffalo 632 Kimball Tower Buffalo 14214 NY United States Department of Biostatistics Roswell Park Comprehensive Cancer Center Elm and Carlton Streets Buffalo 14263 New York United States

Introduction: Investigations of the independent associations of physical inactivity with cancer endpoints have been mounting in the epidemiological literature, in part due to the high prevalence of physical inactivity among cancer patients and to evidence that inactivity associates with carcinogenesis via pathways independent of obesity. Yet, physical inactivity is not currently recognized as a well-established risk or prognostic factor for lung cancer. As such, we examined the associations of lifetime physical inactivity with lung cancer risk and mortality in a hospital-based, case-control study. Presentation of case: materials and methods: The analyses included data from 660 lung cancer patients and 1335 matched cancer-free controls. Multivariable logistic regression analyses were utilized to assess the association between lifetime physical inactivity and lung cancer risk, and Cox proportional hazards models were utilized to estimate the association between lifetime physical inactivity and mortality among lung cancer cases. Results: We observed a significant positive association between lifetime physical inactivity and lung cancer risk: [Odds ratio (OR)=2.23, 95% confidence interval (CI): 1.77–2.81];the association remained significant among never smokers (OR=3.00, 95% CI:1.33-6.78) and non-smokers (OR=2.33, 95% CI: 1.79–3.02). We also observed a significant positive association between lifetime physical inactivity and lung cancer mortality [Hazard ratio (HR)=1.40, 95% CI: 1.14–1.71];the association remained significant in non-smokers (HR=1.51, 95% CI: 1.16–1.96). Discussion/conclusion: These data add to the body of evidence suggesting that physical inactivity is an independent risk and prognostic factor for cancer. Additional research utilizing prospectively collected data is needed to substantiate the current findings. © 2018 Elsevier Ltd

关键词： Lung cancer epidemiology Lung cancer mortality Lung cancer risk Lung cancer survival Physical inactivity

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Correction to: A cluster randomized controlled trial for a multi-level, clinic-based smoking cessation program with women in Appalachian communities: study protocol for the "Break Free" program

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Addiction science & clinical practice 2022年第1期17卷 21页

作者： Joanne G Patterson Tia N Borger Jessica L Burris Mark Conaway Robert Klesges Amie Ashcraft Lindsay Hauser Connie Clark Lauren Wright Sarah Cooper Merry C Smith Mark Dignan Stephenie Kennedy-Rea Electra D Paskett Roger Anderson Amy K Ferketich Division of Epidemiology College of Public Health The Ohio State University 354 Cunz Hall 1841 Neil Avenue Columbus OH 43210 USA. patterson.1191@osu.edu. The Ohio State University Comprehensive Cancer Center Columbus OH USA. patterson.1191@osu.edu. Department of Psychology University of Kentucky Lexington KY USA. Department of Public Health Sciences University of Virginia Charlottesville VA USA. School of Medicine University of Virginia Charlottesville VA USA. West Virginia University Morgantown WV USA. UVA Cancer Center University of Virginia Charlottesville VA USA. College of Public Health The Ohio State University Columbus OH USA. Department of Internal Medicine College of Medicine University of Kentucky Lexington KY USA. Markey Cancer Center University of Kentucky Lexington KY USA. West Virginia University Cancer Institute Morgantown WV USA. Department of Medicine School of Medicine West Virginia University Morgantown WV USA. Division of Epidemiology College of Public Health The Ohio State University 354 Cunz Hall 1841 Neil Avenue Columbus OH 43210 USA. The Ohio State University Comprehensive Cancer Center Columbus OH USA. Division of Cancer Prevention and Control Department of Internal Medicine College of Medicine The Ohio State University Columbus OH USA.

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Fear of cancer Recurrence Associated with Perceived Cognitive Impairment among Women with cancers: Findings from the Women's Health Initiative Life and Longevity After cancer Study

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Preventive oncology & epidemiology 2023年第1期1卷 2292359页

作者： Yesol Yang Eric M McLaughlin Michelle J Naughton Diane Von Ah Nazmus Saquib Judith E Carroll Lihong Qi Dorothy S Lane Tonya S Orchard Electra D Paskett Department of Internal Medicine The Ohio State University Comprehensive Cancer Center-James Columbus OH USA. The Ohio State University Center for Biostatistics Columbus OH USA. Division of Cancer Prevention and Control Department of Medicine College of Medicine The Ohio State University Columbus OH USA. College of Nursing Center for Healthy Aging Self-Management and Complex Care The Ohio State University Columbus OH USA. College of Medicine Sulaiman AlRajhi University Albukairiyah Saudi Arabia. Department of Psychiatry Cousins Center for Psychoneuroimmunology University of California Los Angeles David Geffen School of Medicine Jane & Terry Semel Institute for Neuroscience & Human Behavior Los Angeles CA USA. Department of Public Health Sciences School of Medicine University of California Davis Davis CA USA. Department of Family Population & Preventive Medicine Renaissance School of Medicine Stony Brook University Stony Brook NY USA. Human Nutrition Program Department of Human Sciences College of Education and Human Ecology The Ohio State University Columbus OH USA.

Background:Perceived cognitive impairments(PCI) are the most common complications that Non-Central Nervous System (Non-CNS) cancers survivors experience. Studies have suggested that those who expreience fear of cancer recurrence (FCR) tend to report cognitive problems; however, this association has not been examined. Methods:Participants (n = 6,714) were enrolled in the Women's Health Initiative Life and Longevity After cancer study. FCR was assessed using the cancer Worry Scale and PCI was assessed using the PCI subscale of FACT-Cog. The association between FCR and PCI was analyzed using univariable and multivariable logistic regression models. A cut off score of ≥ 14 is indicative of high FCR and below 14 indicating low FCR. Scores lower than 60 indicated PCI. Result:The multivariable model showed that higher FCR corresponded to an increase in odds of PCI (OR = 1.15, < 0.001). We also found that older age at diagnosis ( < 0.001), less social support ( = 0.01), over ten pounds of weight gain after cancer treatment ( = 0.02), and mild or worse anxiety ( < 0.001) were also associated with increased odds of PCI from the multivariable analysis. Discussion:Our findings indicate that survivors with higher FCR demonstrated poorer cognitive performance than those with lower FCR. These results suggest that those with higher FCR are more likely to report PCI.

关键词： cancer survivors Cognition Fear of cancer recurrence Older women

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Obstetric Outcomes in Young Women with Breast cancer: Prior, Postpartum, and Subsequent Pregnancies

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American Journal of Perinatology 2019年第4期37卷 370-374页

作者： Kimberly K. Ma Courtney J. Preusse Philip A. Stevenson Veronica L. Winget Jean A. McDougall Christopher I. Li Vijayakrishna K. Gadi Hilary S. Gammill Department of Obstetrics and Gynecology University of Washington Seattle Washington Division of Clinical Research Fred Hutchinson Cancer Research Center Seattle Washington Division of Epidemiology Biostatistics and Preventive Medicine University of New Mexico Albuquerque New Mexico Cancer Control and Population Sciences Program University of New Mexico Comprehensive Cancer Center Albuquerque New Mexico Division of Public Health Sciences Fred Hutchinson Cancer Research Center Seattle Washington Division of Medical Oncology University of Washington Seattle Washington

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Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women

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Gynecologic oncology 2019年第2期153卷 343-355页

作者： Kate Lawrenson Fengju Song Dennis J Hazelett Siddhartha P Kar Jonathan Tyrer Catherine M Phelan Rosario I Corona Norma I Rodríguez-Malavé Ji-Hei Seo Emily Adler Simon G Coetzee Felipe Segato Marcos A S Fonseca Christopher I Amos Michael E Carney Georgia Chenevix-Trench Jiyeob Choi Jennifer A Doherty Weihua Jia Gang J Jin Byoung-Gie Kim Nhu D Le Juyeon Lee Lian Li Boon K Lim Noor A Adenan Mika Mizuno Boyoung Park Celeste L Pearce Kang Shan Yongyong Shi Xiao-Ou Shu Weiva Sieh Pamela J Thompson Lynne R Wilkens Qingyi Wei Yin L Woo Li Yan Beth Y Karlan Matthew L Freedman Houtan Noushmehr Ellen L Goode Andrew Berchuck Thomas A Sellers Soo-Hwang Teo Wei Zheng Keitaro Matsuo Sue Park Kexin Chen Paul D P Pharoah Simon A Gayther Marc T Goodman Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute Cedars-Sinai Medical Center 8700 Beverly Boulevard Suite 290W Los Angeles CA USA Center for Bioinformatics and Functional Genomics Cedars Sinai Genomics Core Cedars-Sinai Medical Center Los Angeles CA USA. Electronic address: kate.lawrenson@***. National Clinical Research Center for Cancer Tianjin Medical University Cancer Institute and Hospital Tianjin China Department of Epidemiology and Biostatistics Key Laboratory of Cancer Prevention and Therapy Tianjin China. Center for Bioinformatics and Functional Genomics Cedars Sinai Genomics Core Cedars-Sinai Medical Center Los Angeles CA USA. Department of Oncology Centre for Cancer Genetic Epidemiology University of Cambridge Strangeways Research Laboratory Cambridge UK. Department of Gynecologic Oncology Moffitt Cancer Center Tampa FL USA Department of Cancer Epidemiology Moffitt Cancer Center Tampa FL USA. Center for Bioinformatics and Functional Genomics Cedars Sinai Genomics Core Cedars-Sinai Medical Center Los Angeles CA USA. Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA. Department of Preventive Medicine University of Southern California Keck School of Medicine 1450 Biggy Street Los Angeles CA USA. Department of Genetics Ribeirão Preto Medical School University of São Paulo 14049-900 Brazil. Institute for Clinical and Translational Research Department of Medicine Baylor School of Medicine HoustonTX USA. Department of Obstetrics and Gynecology John A. Burns School of Medicine University of Hawaii Honolulu HI USA. Genetics and Computational Biology Department QIMR Berghofer Medical Research Institute 300 Herston Road Herston QLD 4006 Australia. Department of Preventive Medicine Seoul National University College of Medicine Seoul Republic of Korea Cancer Research Institute Seoul National University Seoul Republic of Korea Department of Biomedical Science Graduate School Seoul National Un

OBJECTIVE:Genome-wide association studies (GWASs) for epithelial ovarian cancer (EOC) have focused largely on populations of European ancestry. We aimed to identify common germline variants associated with EOC risk in Asian women. METHODS:Genotyping was performed as part of the OncoArray project. Samples with >60% Asian ancestry were included in the analysis. Genotyping was performed on 533,631 SNPs in 3238 Asian subjects diagnosed with invasive or borderline EOC and 4083 unaffected controls. After imputation, genotypes were available for 11,595,112 SNPs to identify associations. RESULTS:At chromosome 6p25.2, SNP rs7748275 was associated with risk of serous EOC (odds ratio [OR] = 1.34, P = 8.7 × 10) and high-grade serous EOC (HGSOC) (OR = 1.34, P = 4.3 × 10). SNP rs6902488 at 6p25.2 (r = 0.97 with rs7748275) lies in an active enhancer and is predicted to impact binding of STAT3, P300 and ELF1. We identified additional risk loci with low Bayesian false discovery probability (BFDP) scores, indicating they are likely to be true risk associations (BFDP <10%). At chromosome 20q11.22, rs74272064 was associated with HGSOC risk (OR = 1.27, P = 9.0 × 10). Overall EOC risk was associated with rs10260419 at chromosome 7p21.3 (OR = 1.33, P = 1.2 × 10) and rs74917072 at chromosome 2q37.3 (OR = 1.25, P = 4.7 × 10). At 2q37.3, expression quantitative trait locus analysis in 404 HGSOC tissues identified ESPNL as a putative candidate susceptibility gene (P = 1.2 × 10). CONCLUSION:While some risk loci were shared between East Asian and European populations, others were population-specific, indicating that the landscape of EOC risk in Asian women has both shared and unique features compared to women of European ancestry.

关键词： Asian ancestry Enhancer Epithelial ovarian cancer Gene regulation Genome-wide association study eQTL

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Publisher Correction: Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020

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Eye (London, England) 2024年第11期38卷 2229-2231页

作者： Konrad Pesudovs Hugh R. Taylor Tabassom Sedighi Rupert R. A. Bourne Shahina Pardhan Van Charles Lansingh John H. Kempen Ian Tapply Arthur G. Fernandes Maria Vittoria Cicinelli Alessandro Arrigo Nicolas Leveziel Serge Resnikoff Seth Flaxman Mukkharram M. Bikbov Tasanee Braithwaite Alain Bron Ching-Yu Cheng Monte A. Del Monte Joshua R. Ehrlich Leon B. Ellwein David Friedman João M. Furtado Gus Gazzard Ronnie George M. Elizabeth Hartnett Jost B. Jonas Rim Kahloun Moncef Khairallah Rohit C. Khanna Janet Leasher Julie-Anne Little Vinay Nangia Michal Nowak Tunde Peto Pradeep Ramulu Fotis Topouzis Mitiadis Tsilimbaris Ya Xing Wang Ningli Wang Paul Svitil Briant Theo Vos Katrin Burkart Kaleb Coberly Xiaochen Dai Stephen S. Lim Tomislav Mestrovic Ali H. Mokdad Christopher J. L. Murray Jaimie D. Steinmetz Awoke Misganaw Yohannes Habtegiorgis Abate Mohammad Abdollahi Mozhan Abdollahi Ayele Mamo Abebe Olumide Abiodun Richard Gyan Aboagye Woldu Aberhe Abrha Hasan Abualruz Hiwa Abubaker Ali Eman Abu-Gharbieh Salahdein Aburuz Tadele Girum Girum Adal Mesafint Molla Adane Isaac Yeboah Addo Qorinah Estiningtyas Sakilah Adnani Muhammad Sohail Afzal Muhammad Umair Shahin Aghamiri Bright Opoku Ahinkorah Aqeel Ahmad Sajjad Ahmad Ali Ahmadi Siamak Sabour Ayman Ahmed Haroon Ahmed Ahmad Samir Alfaar Abid Ali Syed Shujait Shujait Ali Awais Altaf Hubert Amu Emmanuel Manu Sofia Androudi Rodrigo Anguita Abhishek Anil Rimple Jeet Kaur Muhammad Aaqib Shamim Saeid Anvari Anayochukwu Edward Anyasodor Francis Appiah Jalal Arabloo Haleh Ayatollahi Mosab Arafat Damelash Areda Reza Arefnezhad Brhane Berhe Aregawi Akeza Awealom Asgedom Tahira Ashraf Seyyed Shamsadin Athari Bantalem Tilaye Tilaye Atinafu Birhan Tsegaw Taye Maha Moh’d Wahbi Atout Alok Atreya Ahmed Y. Azzam Hassan Babamohamadi Sara Bagherieh Yogesh Bahurupi Atif Amin Baig Shumaila Nargus Biswajit Banik Mainak Bardhan Saurav Basu Kavita Batra Nebiyou Simegnew Bayileyegn Fatemeh Bazvand Addisu Shunu Beyene Awoke Masrie Asrat Derese Devidas S. Bhagat Akshaya Srikanth Bhagavathula Pankaj Bh Medicine & Health University of New South Wales Sydney NSW Australia School of Optometry and Vision Science University of New South Wales Sydney NSW Australia School of Population and Global Health University of Melbourne Carlton VIC Australia Vision and Eye Research Institute Anglia Ruskin University Cambridge UK HelpMeSee Instituto Mexicano de Oftalmologia Santiago de Querétaro Mexico University of Miami Gables FL USA University of Utah Salt Lake City UT USA Chief Medical Office HelpMeSee New York NY USA Mexican Institute of Ophthalmology Queretaro Mexico Department of Ophthalmology Massachusetts Eye and Ear/Shepens Eye Research Institute/Harvard Medical School Boston MA USA Eye Unit MyungSung Christian Medical Center (MCM) Comprehensive Specialized Hospital and MyungSun Medical College Addis Ababa Ethiopia Department of Ophthalmology Addis Ababa University Addis Ababa Ethiopia Sight for Souls Bellevue WA USA Department of Ophthalmology Harvard University Boston MA USA Eye Unit MyungSung Medical College Addis Ababa Ethiopia Addenbrooke’s Hospital Cambridge UK Department of Ophthalmology Cambridge University Hospitals Cambridge UK Federal University of Sao Paolo Sao Paolo SP Brazil University of Calgary Calgary AB Canada Department of Ophthalmology and Visual Sciences Federal University of São Paulo Sao Paulo Brazil School of Medicine Vita-Salute San Raffaele University Milan Italy Department of Ophthalmology IRCCS San Raffaele Scientific Institute Milan Italy Department of Ophthalmology San Raffaele Scientific Institute Milano Italy IRCCS San Raffaele Scientific Institute Vita-Salute University Milan Italy Scientific Institute San Raffaele Hospital Vita-Salute University Milan Italy University of Poitiers Poitiers France CHU de Poitiers Poitiers France Ophthalmology Department CHU de Poitiers (Poitiers University Hospital) Poitiers France Unité 1084 National Institute of Health and Medical Research (INSERM) Poitiers France

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