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Deep transfer learning-based decoder calibration for intracortical brain-machine interfaces

Computers in Biology and Medicine 2025年第Pt A期192卷 110231-110231页

作者： Li, Xiao Dong, Xianxin Wang, Jun Mao, Haodong Tu, Xikai Li, Wei He, Jiping Li, Qiang Zhang, Peng Hubei Key Laboratory of Modern Manufacturing Quantity Engineering School of Mechanical Engineering Hubei University of Technology Wuhan430068 China Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology Hubei Wuhan China MoE Key Laboratory for Biomedical Photonics Collaborative Innovation Center for Biomedical Engineering School of Engineering Sciences Huazhong University of Science and Technology Hubei Wuhan China The Key Laboratory of Ministry of Education for Image Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Hubei Wuhan China Advanced Innovation Center for Intelligent Robots and Systems Beijing Institute of Technology Beijing China

Intracortical brain-machine interfaces (iBMIs) aim to establish a communication path between the brain and external devices. However, in the daily use of iBMIs, the non-stationarity of recorded neural signals necessitates frequent recalibration of the iBMI decoder to maintain decoding performance, which requires collecting and labeling a large amount of new data. To address this challenge and minimize the time needed for decoder recalibration, we proposed an active learning domain adversarial neural network (AL-DANN). This model leveraged a substantial volume of historical data alongside a small amount of current data (four samples per category) to calibrate the decoder. By incorporating domain adversarial and active learning strategies, the model effectively transferred knowledge from historical data to new data, reducing the demand for new samples. We validated the proposed method using neural signals recorded from three monkeys performing different movements in a classification task or a regression task. The results showed that the AL-DANN outperformed existing state-of-the-art methods. Impressively, it required only four new samples per category for decoder recalibration, leading to a recalibration time reduction of over 80 %. To our knowledge, this is the first study to incorporate deep transfer learning into iBMI decoder calibration, highlighting the significant potential of applying deep learning technologies in iBMIs. © 2025

关键词： Adversarial machine learning

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GEM: Context-Aware Gaze EstiMation with Visual Search Behavior Matching for Chest Radiograph

arXiv

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arXiv 2024年

作者： Liu, Shaonan Chen, Wenting Liu, Jie Luo, Xiaoling Shen, Linlin Computer Vision Institute College of Computer Science and Software Engineering Shenzhen University China Department of Electrical Engineering City University of Hong Kong Hong Kong AI Research Center for Medical Image Analysis and Diagnosis Shenzhen University China Guangdong Provincial Key Laboratory of Intelligent Information Processing China

Gaze estimation is pivotal in human scene comprehension tasks, particularly in medical diagnostic analysis. Eye-tracking technology facilitates the recording of physicians’ ocular movements during image interpretation, thereby elucidating their visual attention patterns and information-processing strategies. In this paper, we initially define the context-aware gaze estimation problem in medical radiology report settings. To understand the attention allocation and cognitive behavior of radiologists during the medical image interpretation process, we propose a context-aware Gaze EstiMation (GEM) network that utilizes eye gaze data collected from radiologists to simulate their visual search behavior patterns throughout the image interpretation process. It consists of a context-awareness module, visual behavior graph construction, and visual behavior matching. Within the context-awareness module, we achieve intricate multimodal registration by establishing connections between medical reports and images. Subsequently, for a more accurate simulation of genuine visual search behavior patterns, we introduce a visual behavior graph structure, capturing such behavior through high-order relationships (edges) between gaze points (nodes). To maintain the authenticity of visual behavior, we devise a visual behavior-matching approach, adjusting the high-order relationships between them by matching the graph constructed from real and estimated gaze points. Extensive experiments on four publicly available datasets demonstrate the superiority of GEM over existing methods and its strong generalizability, which also provides a new direction for the effective utilization of diverse modalities in medical image interpretation and enhances the interpretability of models in the field of medical imaging. https://***/Tiger-SN/GEM. Copyright © 2024, The Authors. All rights reserved.

关键词： Eye movements

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Distributed Autonomous Swarm Formation for Dynamic Network Bridging

Distributed Autonomous Swarm Formation for Dynamic Network B...

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IEEE Conference on Computer Communications Workshops, INFOCOM Wksps

作者： Raffaele Galliera Thies Mohlenhof Alessandro Amato Daniel Duran Kristen Brent Venable Niranjan Suri Institute for Human & Machine Cognition (IHMC) Department of Intelligent Systems & Robotics The University of West Florida (UWF) Pensacola FL USA Fraunhofer Institute for Communication Information Processing and Ergonomics (FKIE) Wachtberg Germany US Army Research Laboratory (ARL) Adelphi MD USA

ISBN: (数字)9798350384475

ISBN: (纸本)9798350384482

Effective operation and seamless cooperation of robotic systems are a fundamental component of next-generation technologies and applications. In contexts such as disaster response, swarm operations require coordinated behavior and mobility control to be handled in a distributed manner, with the quality of the agents' actions heavily relying on the communication between them and the underlying network. In this paper, we formulate the problem of dynamic network bridging in a novel Decentralized Partially Observable Markov Decision Process (Dec-POMDP), where a swarm of agents cooperates to form a link between two distant moving targets. Furthermore, we propose a Multi-Agent Reinforcement Learning (MARL) approach for the problem based on Graph Convolutional Reinforcement Learning (DGN) which naturally applies to the networked, distributed nature of the task. The proposed method is evaluated in a simulated environment and compared to a centralized heuristic baseline showing promising results. Moreover, a further step in the direction of sim-to-real transfer is presented, by additionally evaluating the proposed approach in a near Live Virtual Constructive (LVC) UAV framework.

关键词： Training Robot kinematics Markov decision processes Disasters Conferences Reinforcement learning Autonomous aerial vehicles

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A frequency and beamwidth reconfigurable antenna based on liquid crystal for 5G millimeter waves

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Scientific Reports 2025年第1期15卷 1-10页

作者： Chen, Peng Wang, Xinju Wang, Dan Gan, Zongsheng Yin, Yutong Zhang, Haowei School of Ocean Information Engineering Jimei University Xiamen 361021 China Fujian Provincial Key Laboratory of Maritime Communication and Intelligent Electronic Systems Jimei University Xiamen 361021 China Fujian Provincial Key Laboratory of Oceanic Information Perception and Intelligent Processing Jimei University Xiamen 361021 China Tianfu Xinglong Lake Laboratory Instrument Platform Department Chengdu 610200 China

In this paper, a novel frequency and beamwidth reconfigurable antenna is proposed. The antenna features a 5-layer vertically stacked structure with the dimensions of, and the layers from top to bottom are the radiating layer, the orientation layer, the liquid crystal (LC) layer, the orientation layer, and the ground layer, and a liquid crystal cavity integrated into the LC layer. An inverted microstrip feed line structure is employed as the bias electrode, and connecting it to a coaxial line side-feed adapter for excitation of the antenna. To investigate the beamwidth reconfigurability, two parasitic dipole structures-all disconnected or connected-are placed on either side of the main radiating element for comparative analysis. Experimental results reveal that the antenna’s resonance frequency shifts from 31.78 GHz to 27.1 GHz, providing a frequency reconfigurable range of 14.73%. Notably, this frequency tuning process is minimally influenced by the type of parasitic patch. Additionally, the impedance bandwidth and -3dB beamwidth of the antenna remain largely unaffected by the reconfiguration. Testing the antenna with different parasitic patch structures, the -3dB beamwidth of the antenna expands from to at for the LC, and from to at, and the antenna peak gain of 6.04 dBi and 7.58 dBi, separately. These results correspond to a reconfigurable range of 64.75% and 40.89% for the -3dB beamwidth, respectively. © This is a U.S. Government work and not under copyright protection in the US;foreign copyright protection may apply 2025.

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Identification of Prognostic Signature in Esophageal Cancer Based on Network Analysis 15th

Identification of Prognostic Signature in Esophageal Cancer ...

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15th International Conference on Bio-Inspired Computing: Theories and Applications, BIC-TA 2020

作者： Ma, Jianfei Huang, Yabing Key Laboratory of Image Information Processing and Intelligent Control School of Artificial Intelligence and Automation Huazhong University of Science and Technology Luoyu Road 1037 Wuhan430074 China Department of Pathology Renmin Hospital of Wuhan University Wuhan430060 China

ISBN: (纸本)9789811613531

Esophageal cancer is the 6th most common cancer in the world with a five-year survival among 15 % to 25 % patients. It’s of great significance to identify prognostic signature for precise prediction of patient survival. In this work, we use a network-based approach to identify the disease genes of esophageal cancer. We construct the co-expression networks of normal and cancer samples by interpreting the gene expression profile and further divide the networks into inactivated subnetwork and enhanced subnetwork. Functional enrichment analysis shows that phosphoprotein and acetylation are both enriched in the inactivated genes and enhanced genes. Furthermore, 5 kinesin family members, KIF11, KIF23, KIF18A, KIF18B, and KIF2A, are all found to be significantly enhanced, suggesting that kinesin is crucial in promoting the formation of esophageal cancer. The 11 genes both inactivated and enhanced in the process of tumor development are found to be prognosis-associated and perform well in evaluating the survival of esophageal cancer patients. This study provides us fundamental recognition about the functional dysregulation in esophageal cancer and help to identify the biomarker for the further development of therapeutic targets. © 2021, Springer Nature Singapore Pte Ltd.

关键词： Diseases

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Sample Weighted Gradient Regularization for Source-Free Domain Adaptation

SSRN

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SSRN 2024年

作者： Long, Yunchong Xu, Bingrong Zhang, Qingyong Yin, Jianhua Zeng, Zhigang School of Automation Wuhan University of Technology Wuhan430070 China Intelligent Transportation Systems Research Center Wuhan University of Technology Wuhan430063 China The Engineering Research Center of Transportation Information and Safety Ministry of Education Wuhan430063 China School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China The Key Laboratory of Image Processing and Intelligent Control Education Ministry of China Wuhan430074 China

Conventional Domain Adaptation(DA) algorithms typically rely on access to the source data,which may not always be practical due to privacy concerns or limited storage *** address these challenges,Source-Free Domain Adaptation(SFDA) has emerged as an alternative that relies solely on a pre-trained source model rather than the actual source *** SFDA,pseudo-label supervised learning is commonly employed and initially plays a significant role in enhancing model performance during the early stages of target domain ***,as adaptation progresses,the performance can stagnate or even deteriorate due to the noise inherent in pseudo-labels,a phenomenon known as Confirmation *** noise present in target domain pseudo-labels introduces additional uncertainty and overfitting risks to the *** this study,a novel framework named Sample Weighted Gradient Regularization (SWGR) was introduced to tackle this *** first propose the Label Uncertainty Estimation Metric (LUEM),a reweighting strategy that assesses the reliability of *** metric evaluates label uncertainty from both the source domain pre-trained model and spatial distribution of target domain samples,allowing the model to achieve improved cross-domain transfer performance with high-confidence samples in the target domain. Additionally,we impose a constraint on the gradient descent process of the total loss function in the form of an inequality to prevent entropy from *** Gradient Regularization eliminates overfitting while also guiding the model in lowering prediction uncertainty *** approach reduces the uncertainty in the target domain and enhances the model's generalization *** results demonstrate that our method surpasses competing SFDA approaches and even outperforms many traditional DA methods which require extensive amounts of source domain data. © 2024, The Authors. All rights reserved.

关键词： Self-supervised learning

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Large, Complex, and Realistic Safety Clothing and Helmet Detection: Dataset and Method

arXiv

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arXiv 2023年

作者： Yu, Fusheng Li, Jiang Wang, Xiaoping Wu, Shaojin Zhang, Junjie Zeng, Zhigang The School of Artificial Intelligence and Automation Huazhong University of Science and Technology Wuhan430074 China The Institute of Artificial Intelligence Huazhong University of Science and Technology Wuhan430074 China The Hubei Key Laboratory of Brain-Inspired Intelligent Systems Huazhong University of Science and Technology Wuhan430074 China The Key Laboratory of Image Processing and Intelligent Control Huazhong University of Science and Technology Ministry of Education Wuhan430074 China

Detecting safety clothing and helmets is paramount for ensuring the safety of construction workers. However, the development of deep learning models in this domain has been impeded by the scarcity of high-quality datasets. In this study, we construct a large, complex, and realistic safety clothing and helmet detection (SFCHD) dataset. SFCHD is derived from two authentic chemical plants, comprising 12,373 images, 7 categories, and 50,552 annotations. We partition the SFCHD dataset into training and testing sets with a ratio of 4:1 and validate its utility by applying several classic object detection algorithms. Furthermore, drawing inspiration from spatial and channel attention mechanisms, we design a spatial and channel attention-based low-light enhancement (SCALE) module. SCALE is a plug-and-play component with a high degree of flexibility. Extensive evaluations of the SCALE module on both the ExDark and SFCHD datasets have empirically demonstrated its efficacy in enhancing the performance of detectors under low-light conditions. The dataset and code are publicly available at https://***/lijfrankopen/SFCHD-SCALE. Copyright © 2023, The Authors. All rights reserved.

关键词： Chemical plants

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Isoform Function Prediction Based on Heterogeneous Graph Attention Networks

Isoform Function Prediction Based on Heterogeneous Graph Att...

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IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

作者： Kuo Guo Yifan Li Hao Chen Hong-Bin Shen Yang Yang Department of Computer Science and Engineering Shanghai Jiao Tong University and Key Laboratory of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering Shanghai China Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University and Key Laboratory of System Control and Information Processing Ministry of Education of China Shanghai China Computational Biology Department School of Computer Science Carnegie Mellon University Pittsburgh PA USA

Isoforms refer to different mRNA molecules transcribed from the same gene, which can be translated into proteins with varying structures and functions. Predicting the functions of isoforms is an essential topic in bioinformatics as it can provide valuable insights into the intricate mechanisms of gene regulation and biological processes. Conventionally, gene function labels are standardized in Gene Ontology (GO) terms. However, traditional methods for predicting isoform function are largely limited by the absence of isoform-specific labels, sparse annotations, and the vast number of GO terms. To address these issues, we propose HANIso, a deep learning-based method for isoform function prediction. HANIso leverages a pretrained protein language model to extract features from protein sequences. It also integrates heterogeneous information, such as isoform sequence features, GO annotations, and isoform interaction data, using a Heterogeneous Graph Attention Network (HAN). This allows the model to learn the importance of different sources of information and their semantic relationships through the attention mechanism. Our method can predict function labels at both the gene level and isoform level. We conduct experiments on two species datasets, and the results demonstrate that our method outperforms existing methods on both AUROC and AUPRC. HANIso has the potential to overcome the limitations of traditional methods and provide a more accurate and comprehensive understanding of isoform function.

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IRS/UAV-Based Edge-Computing and Traffic-Offioading Over 6G THz Mobile Wireless Networks

IRS/UAV-Based Edge-Computing and Traffic-Offioading Over 6G ...

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IEEE International Conference on Communications (ICC)

作者： Fei Wang Xi Zhang Chongqing Key Laboratory of Non-linear Circuit and Intelligent Information Processing College of Electronic and Information Engineering Southwest University Chongqing China Networking and Information Systems Laboratory Department of Electrical and Computer Engineering Texas A&M University College Station TX USA

intelligent reflecting surface (IRS), unmanned aerial vehicle (UAV), and Terahertz (THz) communications, which are recognized as 6G promising techniques, have attracted significant attentions. We propose UAV energy minimization schemes for IRS/UAV-based mobile-edge-computing (MEC) and traffic-offloading over broadband THz mobile networks. In the networks, multiple UAVs serving as MEC-servers collect data from multiple ground users (GUs) with the assistance of a set of passive IRSs. First, we formulate a UAV energy minimization problem, which jointly optimizes the IRSs' phase shifts, UAVs' trajectories, and system computation and communication resources. For THz communications, since the composite channel power gains of GUs are complicated functions of UAVs' trajectories and IRSs' phase shifts, the formulated optimization problem is non-convex. Then, using the alternating optimization (AO) technique, we decompose this non-convex optimization problem into three sub-problems which then can be iteratively solved. Finally, we validate and evaluate the proposed schemes by numerical analyses, which show that the energy consumption of UAVs can be reduced by around 40% by using IRSs.

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Active-IRS-Enabled Energy-Efficiency Optimizations for UAV-Based 6G Mobile Wireless Networks

Active-IRS-Enabled Energy-Efficiency Optimizations for UAV-B...

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Annual Conference on Information Sciences and systems (CISS)

作者： Fei Wang Xi Zhang Chongqing Key Laboratory of Non-linear Circuit and Intelligent Information Processing College of Electronic and Information Engineering Southwest University Chongqing China Department of Electrical and Computer Engineering Networking and Information Systems Laboratory Texas A&M University College Station TX USA

We propose the novel scheme to solve a multi-objective optimization problem over an unmanned aerial vehicle (UAV) communications system to jointly minimize the energy consumption of the UAV and ground users (GUs). In particular, the UAV communicates with multiple GUs using active intelligent reflecting surfaces (IRSs), which can actively amplify and thus significantly enhance the strengths of reflected signals. We develop an energy minimization scheme based on the multi-objective hierarchical deep reinforcement learning (DRL), by decomposing the formulated optimization problem into two-layered subproblems. By solving the upper-level subproblem, we derive the optimal UAV trajectory and GUs scheduling strategies to minimize the UAV's energy consumption. By solving the lower-level subproblem, we obtain the IRS's phase shifts and amplification factors and GUs' transmit/receive beamforming to minimize the GUs' energy consumption. Finally, we validate and evaluate the proposed schemes through simulations, which show that the UAV's and GUs' energy consumption can be significantly reduced by using the active IRS, when the thermal noise powers at the IRS are much smaller than those at the UAV and GUs.

关键词： Energy consumption Communication systems Wireless networks Reinforcement learning Autonomous aerial vehicles Minimization Thermal noise

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