While many methods have been proposed for detecting disease outbreaks from pre-diagnostic data, their performance is usually not well understood. In this paper, we describe the relationship between forecast accuracy a...
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While many methods have been proposed for detecting disease outbreaks from pre-diagnostic data, their performance is usually not well understood. In this paper, we describe the relationship between forecast accuracy and the detection accuracy of a method. We argue that most existing temporal detection methods for biosurveillance can be characterized as a forecasting component coupled with a monitoring/detection component. We show that improved forecasting results in improved detection and we quantify the relationship between forecast accuracy and detection metrics under different scenarios. The forecast accuracy can then be used to rate an algorithm's expected performance in detecting outbreaks. Simulation is used to compare empirical performance with theoretical results; we also show examples with authentic biosurveillance data.
We investigate statistical properties of a likelihood approach to nonparametric estimation of a singular distribution using deep generative models. More specifically, a deep generative model is used to model high-dime...
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The radiative transfer equation models the interaction of radiation with scattering and absorbing media and has important applications in various fields in science and engineering. It is an integro-differential equati...
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Bistable structures associated with nonlinear deformation behavior, exemplified by the Venus flytrap and slap bracelet, can switch between different functional shapes upon actuation. Despite numerous efforts in modeli...
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Bistable structures associated with nonlinear deformation behavior, exemplified by the Venus flytrap and slap bracelet, can switch between different functional shapes upon actuation. Despite numerous efforts in modeling such large deformation behavior of shells, the roles of mechanical and nonlinear geometric effects on bistability remain elusive. We demonstrate, through both theoretical analysis and tabletop experiments, that two dimensionless parameters control bistability. Our work classifies the conditions for bistability, and extends the large deformation theory of plates and shells.
We extend existing results for the Nielsen complexity of scalar primaries and spinning primaries in four dimensions by including supersymmetry. Specifically, we study the Nielsen complexity of circuits that transform ...
Under suitable assumptions, the algorithms in [Lin, Tong, Quantum 2020] can estimate the ground-state energy and prepare the ground state of a quantum Hamiltonian with near-optimal query complexities. However, this is...
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This paper proposed an amplitude embedding system for digital audio watermarking in the wavelet domain. In this paper, the relationship between the watermarked coefficients and the original coefficients is first prese...
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When is heterogeneity in the composition of an autonomous robotic team beneficial and when is it detrimental? We investigate and answer this question in the context of a minimally viable model that examines the role o...
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Chemotherapy is one of the primary modalities of cancer treatment. Chemotherapy drug administration is a complex problem that often requires expensive clinical trials to evaluate potential regimens. One way to allevia...
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