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ASME 2024 International mechanical engineering Congress and Exposition, IMECE 2024

作者： Hisham, Muhammed Lee, Sungmun Butt, Haider Mechanical & Nuclear Engineering Department Khalifa University Abu Dhabi United Arab Emirates Biomedical Engineering & Biotechnology Department Khalifa University Abu Dhabi United Arab Emirates

ISBN: (纸本)9780791888629

Smart contact lenses offer unique opportunities as personalized, non-invasive devices that simultaneously perform a wide range of functions. However, the actual production of smart contact lenses is rather challenging. Herein, two vat photopolymerization 3D printing techniques are presented for producing multimaterial and multifunctional contact lenses. In the first technique, a contact lens is 3D printed with hollow channels, which are later filled with resin containing different dyes or drugs. In the second method, functionalized structures are directly 3D printed on top of a commercial contact lens. Atto dyes enable red-green and blue-yellow color vision correction. Photochromic dye enables UV monitoring, warning the wearer in case of UV hazards. Multifunctional contact lenses which can perform ocular health monitoring can also be produced through these techniques. Drug delivery is explored from drug-loaded structures added on the contact lens. Herbal eye drops and phenol red were utilized for studying drug release. The dyes and drugs are incorporated into hydroxyethyl methacrylate and polyethylene glycol diacrylate (HEMA:PEGDA) hydrogels. Drug release rate can be varied by varying the drug loading or the hydrogel composition. The multifunctional contact lenses displayed excellent optical and material properties. Drug loaded structures are printed as peripheral structures that do not hinder vision. These multifunctional contact lenses can enable simultaneous color vision correction, health monitoring and drug delivery without disturbing the daily routine of the wearer. The study demonstrates the potential of vat photopolymerization 3D printing for cost-effective production of multifunctional contact lenses. Copyright © 2024 by ASME.

关键词： Photopolymerization

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MXene:From synthesis to environment remediation

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Chinese Journal of Chemical engineering 2023年第9期61卷 260-280页

作者： Ali Nikkhah Hasan Nikkhah Hadis langari Alireza Nouri Abdul Wahab Mohammad Ang Wei Lun Ng law Yong Rosiah Rohani Ebrahim Mahmoudi Department of Chemical and Process Engineering Faculty of Engineering and Built EnvironmentUniversiti Kebangsaan MalaysiaBangi 43600Malaysia Department of Mechanical and Aerospace Engineering University at BuffaloBuffaloUSA Department of Chemical and Biomolecular Engineering University of ConnecticutStorrsUSA Department of Chemistry and Medicinal Chemistry University at BuffaloBuffaloUSA Chemical and Water Desalination Engineering Program College of EngineeringUniversity of SharjahSharjah 27272United Arab Emirates Lee Kong Chian Faculty of Engineering and Science Universiti Tunku Abdul RahmanJalan Sungai LongBandar Sungai LongKajangSelangorMalaysia

A new burgeoning family of two-dimensional(2D)transition metal carbides/nitrides,better known as MXenes,have received extensive attention because of their distinct properties,such as metallic conductivity,good hydrophilicity,large surface area,good mechanical stability,and *** 40 different MXenes have been synthesized,and dozens more structures and properties have been theoretically ***,the recent progress in MXenes development is not well covered in chronological order based on different *** review article focuses on emerging synthesis methods,the properties of MXenes,and mainly the applications of MXenes and MXene-based material family in environmental remediation,a comprehensive review of gaseous and aqueous pollutants treatment.

关键词： MXene 2D materials Wastewater treatment CO_(2)capture Adsorption Photodegradation

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Benchmark Comparison of Infrared Thermography and Temperature Sensitive Paint on a Cone-Cylinder Model in Laminar Mach 7 Flow

Benchmark Comparison of Infrared Thermography and Temperatur...

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AIAA Science and Technology Forum and Exposition, AIAA SciTech Forum 2025

作者： Smith, Cary Dean Edwards, Sophia Gragston, Mark Jenkins, Jacob Siddiqui, Farhan Mechanical Aerospace and Biomedical Engineering Department University of Tennessee Space Institute TullahomaTN United States Department of Aerospace Engineering Texas A and M University College StationTX United States

ISBN: (数字)9781624107238

ISBN: (纸本)9781624107238

Infrared thermography and temperature sensitive paint measurements of surface thermal effects have been performed on a 6-degree half angle cone with a cylindrical shock generator. The heating associated with shock wave-boundary layer interaction under laminar Mach 7 flow in a low enthalpy Ludwieg Tube was detected and converted into calculated heat flux maps of the region of interest. The spatial image quality, time resolution, and measured temperature and heat flux levels were compared for the two diagnostics. Both techniques were demonstrated to resolve strong thermal signatures of an impinged bow shock as well as gradually increasing heating from boundary layer separation under an induced shock wave. The relative performance of each technique to its counterpart is discussed along with considerations of uncertainty. Overall, the two diagnostics are complementary and together can map heating across a full area with high spatial and temporal resolution, making them well-suited for frequent use in academic hypersonic research wind tunnel facilities. © 2025, American Institute of Aeronautics and Astronautics Inc, AIAA. All rights reserved.

关键词： Laminar boundary layer

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Mixed-Reality Simulator for Analysis of Interactions between Humans and Crawler Cranes 13

Mixed-Reality Simulator for Analysis of Interactions between...

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Joint 13th International Conference on Soft Computing and Intelligent Systems and 25th International Symposium on Advanced Intelligent Systems, SCIS and ISIS 2024

作者： Yamanobe, Kenta Yokota, Kazuya Uenoyama, Daigo Fujiura, Daisuke Ogura, Masataka Takahashi, Kengo Abe, Masajiro Nagaoka University of Technology Master's Program in Mechanical Engineering Nagaoka Japan Nagaoka University of Technology Department of Mechanical Engineering Nagaoka Japan Nagaoka University of Technology Bachelor's Program in Mechanical Engineering Nagaoka Japan Nagaoka University of Technology Center for Integrated Technology Support Nagaoka Japan Nagaoka University of Technology Department of System Safety Engineering Nagaoka Japan

ISBN: (纸本)9798350373332

Crawler cranes are used in various applications, including plant construction and civil engineering. However, accidents caused by hazardous events, such as overturning the entire body or overshadowing of a suspended load, can be problematic. Because crawler cranes are large and powerful machines, simulators are required to analyze the relationship between such hazardous events and human operations. This study proposed a framework for a mixed-reality simulator to analyze the interactions between humans and crawler cranes. This framework combined the high-performance graphics capabilities of Unreal Engine 5 with the high-precision multibody dynamics analysis of MATLAB Simscape to create a visually and physically realistic simulation. Moreover, the quantification of the decision-making process was possible based on the eye-tracking information of the operator. This study described the implementation of these features and discussed the prospects for human-crawler crane interaction analysis using this simulator. © 2024 IEEE.

关键词： MATLAB

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Tribology of enzymatically degraded cartilage mimicking early osteoarthritis

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Friction 2023年第9期11卷 1724-1740页

作者： Ke REN Miguel Alejandro REINA MAHECHA Maike HÜBNER Zhiwei CUI Hans J.KAPER Hugo C.VAN DER VEEN Prashant K.SHARMA Department of Biomedical Engineering University Medical Centre GroningenUniversity of GroningenGroningen 9713AVthe Netherlands Department of Mechanical Engineering Eindhoven University of TechnologyEindhoven 5600MBthe Netherlands Department of Orthopedic Surgery University Medical Centre GroningenUniversity of GroningenGroningen 9700RBthe Netherlands

Healthy cartilage is a water-filled super lubricious *** type II provides it structural stability,and proteoglycans absorb water to keep the cartilage in a swollen condition,providing it the ability to creep and provide weeping ***(OA)is a degenerative and debilitating disorder of diarthrodial joints,where articular cartilage damage originates from enzymatic degradation and mechanical damage(wear).The objective of this research is to observe the level of cartilage damage present in knee arthroplasty patients and to understand the friction and creep behavior of enzymatically degraded bovine cartilage in ***(Lat)and medial(Med)condylar cartilages from OA patients undergoing total knee arthroplasty showed signs of enzymatic degradation and mechanical *** cartilages were exposed to collagenase III and chondroitinase ABC to degrade collagen and proteoglycans,*** loss of proteoglycans or collagen network and morphological changes were observed through histology and the atomic force microscope(AFM),respectively.A significant effect on creep due to enzymatic treatment was not *** the enzymatic treatment was found to significantly decrease the coefficient of friction(COF)at 4 N,while higher COF was shown from chondroitinase ABC degraded cartilage at 40 *** III treatment leads to the release of intact proteoglycans at the sliding interface,while chondroitinase ABC treatment leads to the loss of chondroitin sulfate(CS)from the *** ABC-digested bovine cartilage mimicked patient samples the best because of the similar distributions of proteoglycans,collagen network,and friction behavior.

关键词： lubrication cartilage boundary lubrication osteoarthritis(OA)

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Determining the Non-linear Properties of Arterial Vessel in Circle of Willis of Human Specimens

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biomedical Materials and Devices 2024年第2期2卷 1175-1185页

作者： Shafigh, Mohammad Rassoli, Aisa Fatouraee, Nasser Department of Mechanical Engineering Islamshahr Branch Islamic Azad University Department of Mechanical Engineering K.N. Toosi University of Technology Biological Fluid Mechanics Research Laboratory Amirkabir University of Technology (Tehran Polytechnic) Biological Fluid Mechanics Research Laboratory Biomedical Engineering Department Amirkabir University of Technology (Tehran Polytechnic)

Abstract: Diseases of cerebral vessels have close and direct relation with the wall tissue mechanical properties of blood vessels. The mechanical properties of cerebral vessels can be used for purposes such as clinical diagnosis and decision making regarding treatment. Various studies have shown that hyperelastic models are suitable mathematical models for describing the mechanical behavior of cerebral blood vessels. To obtain these properties, 17 specimens of the middle cerebral arteries of were extracted from human cadavers, whose death was not due to diseases of or damages to the cerebral vessels, and were tested with a biaxial tensile test device within twelve hours after harvesting. Stress-stretch diagrams were obtained from experimental data and were fitted by Fung and Mooney-Rivlin equations. For statistical comparison, the samples were divided into three age groups and two gender groups and were subjected to nonparametric statistical analysis. The comparison of the results of different age groups showed that there is a significant difference between “young”, “middle aged” and “old” groups. There was no significant difference between male and female groups. Therefore, the results indicate changes in the wall properties of blood vessels with aging. It was concluded that the samples are stiffer in the circumferential direction than the longitudinal direction. This study showed that using multiparameter hyperelastic fundamental models is useful for mathematical description of the tissue behavior of cerebral vessels. The reported material properties are a proper source for numerical modeling of the cerebral arteries and analyzing the calculations of the intracranial arteries in patients or normal subjects. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC 2024.

关键词： Anisotropic tissue Cerebral blood vessels Fung model Mooney-Rivlin model Nonlinear materials Plane stress

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Investigating the migration of cells with different degrees of metastasis before and after treatment with chemical drugs targeting cytoskeleton structure, steroid and androgen receptor. 31

Investigating the migration of cells with different degrees ...

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31st National and 9th International Iranian Conference on biomedical engineering, ICBME 2024

作者： Ramezani, Sayed Reza Mojra, Afsaneh Tafazzoli-Shadpour, Mohammad K. N. Toosi University of Technology Department of Mechanical Engineering Tehran Iran Amirkabir University of Technology Faculty of Biomedical Engineering Tehran Iran

ISBN: (纸本)9798331529710

Both healthy and cancerous cells have the ability to migrate from one tissue to another. Anticancer drugs can control cell migration through various mechanisms. Although numerous studies have been conducted on cell migration, very few have investigated the effects of drugs with different targets on cell migration. In the present study, the effect of drugs with different targets on the migration of two cell lines, one non-invasive and the other invasive, was examined. Docetaxel drug, which specifically affects the cell's cytoskeleton structure, namely microtubules and actin filaments, was used to assess the effects of drugs that directly target the cytoskeletal structure. In contrast, the effects of Abiraterone Acetate drug and Bicalutamide drug, which act on steroid, androgen receptor and nucleus proteins respectively, were also investigated. For this purpose, the cells were cultured and treated, followed by scratching with scratcher to create a channel between the cells, and then imaged at various time points. Docetaxel drug had a more significant effect on the migration of PC3 cells compared to the other two drugs, likely due to its targeting of the cell's cytoskeletal structure. In LNCAP cells, no significant change in the area of the scratched channel was observed, and after some time, this area even increased. This is due to the nature of LNCAP cells, which are non-invasive and inherently have low migration and after a time, these cells are killed by the drug, leading to an increase in the area. © 2024 IEEE.

关键词： Cell signaling

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Understanding the Effect of Scaffolding on Introductory Ill-Defined Problems in engineering Education 54

Understanding the Effect of Scaffolding on Introductory Ill-...

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54th IEEE Frontiers in Education Conference, FIE 2024

作者： Churakos, Katelyn Markham, Ella Swenson, Jessica Nightingale, Alice University at Buffalo Department of Mechanical and Aerospace Engineering BuffaloNY United States University at Buffalo Department of Biomedical Engineering BuffaloNY United States University at Buffalo Department of Engineering Education BuffaloNY United States

ISBN: (纸本)9798350351507

This full research paper examines the effect of scaffolding on students' engagement with engineering judgment while solving an open-ended modeling problem (OEMP) during an introductory statics course. While traditional engineering coursework involves well-structured homework problems, research shows that open-ended design problems offer opportunities for students to develop fluency in problem solving and practice the use of engineering judgment. However, the transition from traditional, well-structured problems to OEMPs can be difficult for students, highlighting the critical role of scaffolding in introductory OEMP design [1]. In this paper, we interviewed the professor who created and assigned the OEMP to understand the goals of the scaffolding. Next, we analyzed the OEMP written assignment for scaffolding that elicits the use of engineering judgment and statics concepts. Using both data sources, the professors goals and assignment analysis, we coded a video transcript of collaborative work sessions from a group of students as they worked through the OEMP for engineering judgment and identified if students used the correct static concepts in their discussion. The implications of the paper revolve around identifying the level and type of scaffolding that initiates engagement in engineering judgment and statics course material, as well as strategies for improving scaffolding of open-ended problems. These insights aim to assist educators by highlighting effective scaffolding techniques that better align professors goals with the student takeaways. © 2024 IEEE.

关键词： Students

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Enhancing corrosion resistance of MAO coatings on Al alloy LY12 through in situ co-doping with zinc phosphate and cerium phosphate

Corrosion Communications

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Corrosion Communications 2025年第1期17卷 35-43页

作者： Chao Yang Tao Ying Aihui Huang Jian Huang Pinghu Chen Paul K.Chu Xiaoqin Zeng National Engineering Research Center of Light Alloy Net Forming School of Materials Science and Engineering Shanghai Jiao Tong University Shanghai Key Laboratory of Advanced High-Temperature Materials and Precision Forming School of Materials Science and Engineering Shanghai Jiao Tong University Department of Chemistry University of Munich(LMU) College of Mechanical Engineering Key Laboratory of Hunan Province of Equipment Safety Service Technology under Extreme Environment University of South China Department of Physics Department of Materials Science&Engineering and Department of Biomedical Engineering City University of Hong Kong

Corrosion of aluminum（Al） alloys during service limits many applications. Micro-arc oxidation（MAO） coatings can enhance corrosion resistance, but porous defects in the films undermine their effectiveness. Here, by mixing a phosphate electrolyte with soluble Zn and Ce salts, zinc phosphate and cerium phosphate co-doped MAO corrosion-resistant coating is prepared on Al alloy LY12. Zinc phosphate and cerium phosphate are incorporated in situ to form an amorphous encapsulated nanocrystalline structure. During long-term corrosion, Zn2+is released and deposited as corrosion products Zn（OH）2to cover weak corrosion micro-regions in the coating. Simultaneously, Ce3+released from MAO coating co-doped with zinc phosphate/cerium phosphate forms Zn（OH）2/Ce（OH）3due to the small solubility product Kspto further enhance corrosion resistance. Compared to pristine Al alloy,corrosion potential increases from -1.306 to -0.819 VSCE, and corrosion current density decreases by 4 orders of magnitude from 2.6 × 10-6to 2.5 × 10-10A·cm-2. Co-doped MAO coating significantly enhances corrosion resistance of Al alloy LY12 and shows great potential for a wide range of applications.

关键词： Aluminum alloys Micro-arc oxidation coating Corrosion resistance Zinc phosphate Cerium phosphate

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A comprehensive investigation on data redundancy of large battery degradation datasets 15

A comprehensive investigation on data redundancy of large ba...

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15th IEEE Global Reliability and Prognostics and Health Management Conference, PHM-Beijing 2024

作者： Ma, Liang Tian, Jinpeng Zhang, Tieling School of Mechanical Materials Mechatronic and Biomedical Engineering University of Wollongong Wollongong Australia Department of Electrical and Electronic Engineering The Hong Kong Polytechnic University Hong Kong

ISBN: (纸本)9798350354010

Machine learning (ML) methods have demonstrated superiority in state of health (SOH) estimation of lithium ion batteries. Previous work has focused on collecting extensive data to train ML models;however, the richness of the information within these datasets remains unknown. This study systematically investigates redundancy in three datasets to quantitatively assess their information richness. We propose an iterative filtering (IF) method to remove redundant data and evaluate model performance after training on various sizes of the filtered data. The IF method proves more effective than random filtering, which randomly selects a proportion of data from the dataset. Results suggest that the root mean squared error (RMSE) increases by only 10% after removing up to 95% of the training data. The removed data results in lower errors than the test data split from the original dataset, further demonstrating that the removed data lacks new ageing information. Additionally, we demonstrate the generalizability of the proposed data filtering method by training one ML model on data filtered by another ML model. This work highlights that information richness is more important than dataset volume. © 2024 IEEE.

关键词： data redundancy lithium ion batteries machine learning state of health

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