检索结果-内蒙古大学图书馆

3D rotational shear wave elasticity imaging (3D-RSWEI) in anisotropic lattice phantoms

Journal of the mechanical Behavior of biomedical Materials 2025年 170卷 107048页

作者： Srinivasan, Shruthi Eckstein, Kevin N. Yoon, Daniel Rouze, Ned C. Bock, Kaden D. Villacis, Estela Bayly, Philip V. Nightingale, Kathryn R. Department of Biomedical Engineering Duke University DurhamNC United States Mechanical Engineering and Materials Science Washington University St. Louis MO United States

We present ultrasonic 3D rotational shear wave elasticity imaging (3D-RSWEI) characterization of anisotropic 3D-printed hydrogel lattice phantoms that were originally developed for magnetic resonance elastography (MRE) applications. Shear wave speeds versus rotational angle were measured for two 3D-printed hydrogel lattices while submerged in water and after embedding in different stiffnesses of isotropic poly-vinyl alcohol (PVA). Shear wave propagation in the lattices was anisotropic, with faster wave speeds parallel to the scaling direction of the lattices. We observed that shear wave speeds and shear anisotropy decreased when the lattices were embedded in PVA versus submerged in water. Shear wave dispersion was observed in the lattice+PVA phantoms, with greater dispersion in the direction parallel to the scaling direction versus perpendicular. Dynamic shear testing results of the lattice+PVA phantoms were compared to 3D-RSWEI characterization with differences of 8.4% and 24.1% for propagation parallel and perpendicular to the scaling direction. These results demonstrate the feasibility of ultrasonic SWEI characterization of novel anisotropic MRE lattice phantoms. © 2025

关键词： Shear waves

来源：评论

学校读者我要写书评

暂无评论

Ultra-Cold Cryogenic TEM with Liquid Helium and High Stability

arXiv

引用

arXiv 2024年

作者： Rennich, Emily Sung, Suk Hyun Agarwal, Nishkarsh Gates, Maya Kerns, Robert Hovden, Robert Baggari, Ismail El The Rowland Institute at Harvard Harvard University CambridgeMA02142 United States Department of Mechanical Engineering University of Michigan Ann ArborMI48109 United States Department of Materials Science and Engineering University of Michigan Ann ArborMI48109 United States Michigan Center for Materials Char-acterization University of Michigan Ann ArborMI48109 United States Applied Physics Program University of Michigan Ann ArborMI48109 United States

Cryogenic transmission electron microscopy has revolutionized structural biology and materials science, but achieving temperatures below the boiling point of liquid nitrogen remains a long-standing aspiration. We introduce an ultra-cold liquid helium transmission electron microscope specimen holder, featuring continuous cryogen flow and vibration decoupling. This instrument is compatible with modern aberration-corrected microscopes and achieves sub-25 K base temperature, ±2 mK thermal stability over many hours, and atomic resolution—setting the stage for a new era of cryogenic electron microscopy. © 2024, CC BY.

关键词： High resolution transmission electron microscopy

来源：评论

学校读者我要写书评

暂无评论

A mobile phone-operated nucleic acid diagnostic platform for detection of urinary tract infection (UTI) 21

A mobile phone-operated nucleic acid diagnostic platform for...

引用

21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

作者： Shin, Dong Jin Chen, Liben Li, Chenglong Trick, Alexander Wang, Tza-Huei Department of Mechanical Engineering Johns Hopkins University Baltimore United States College of Veterinary Medicine China Agricultural University Beijing China Department of Biomedical Engineering Johns Hopkins University Baltimore United States

ISBN: (纸本)9780692941836

Rapid and culture-free detection of E. coli directly in urine sample can enable diagnosis of bacterial infection in the urinary tract. We demonstrate a portable, mobile phone-operated nucleic acid test platform to purify and detect E. coli DNA from urine sample in an automated manner. With minimal hands-on time and a total time-to-result of 65 minutes, our platform could play a role in improving antibacterial stewardship in acute care settings. © 17CBMS-0001.

关键词： Cellular telephones

来源：评论

学校读者我要写书评

暂无评论

A Whole Head Ultra-High Density Diffuse Optical Tomography System for Naturalistic and Resting State Functional Human Brain Mapping

A Whole Head Ultra-High Density Diffuse Optical Tomography S...

引用

Optics and the Brain, BRAIN 2023 - Part of Optica Biophotonics Congress: Optics in the Life Sciences 2023

作者： Fogarty, Morgan Rafferty, Sean M. O’Sullivan, Anthony C. Svoboda, Calamity F. Markow, Zachary E. Richter, Edward J. George, Tessa King, Kelsey Wilhelm, Dana Tripathy, Kalyan Trobaugh, Jason W. Eggebrecht, Adam T. Culver, Joseph P. Imaging Science Program Washington University in St. Louis 1 Brookings Drive St. LouisMO63130 United States Department of Biomedical Engineering Washington University in St. Louis 1 Brookings Drive St. LouisMO63130 United States Department of Neuroscience Washington University in St. Louis 1 Brookings Drive St. LouisMO63130 United States Department of Electrical and Systems Engineering Washington University in St. Louis 1 Brookings Drive St. LouisMO63130 United States Department of Radiology Washington University in St. Louis 1 Brookings Drive St. LouisMO63130 United States Department of Physics Washington University in St. Louis 1 Brookings Drive St. LouisMO63130 United States

High-density diffuse optical tomography uses a dense array of overlapping measurements that provides functional brain images validated against fMRI. We doubled this optode density, improving resolution and expanding t... 详细信息

ISBN: (纸本)9781957171210

关键词： Diffuse optical tomography Functional imaging Image quality Magnetic resonance imaging Near infrared spectroscopy Optical imaging

来源：评论

学校读者我要写书评

暂无评论

Reflection-mode optical diffraction tomography for label-free imaging of thick biological specimens

arXiv

引用

arXiv 2022年

作者： Kang, Sungsam Zhou, Renjie Brelen, Marten Mak, Heather K. So, Peter T.C. Yaqoob, Zahid Laser Biomedical Research Center G. R. Harrison Spectroscopy Laboratory Massachusetts Institute of Technology CambridgeMA02139 United States Department of Biomedical Engineering The Chinese University of Hong Kong Hong Kong Department of Ophthalmology and Visual Sciences The Chinese University of Hong Kong Hong Kong Department of Mechanical Engineering Massachusetts Institute of Technology CambridgeMA02139 United States Department of Biological Engineering Massachusetts Institute of Technology CambridgeMA02139 United States

Optical diffraction tomography (ODT) has emerged as a powerful label-free three-dimensional (3D) bioimaging techniques for observing living cells and thin tissue layers. We report a new reflection-mode ODT (rODT) method for imaging thick biological specimens with ~ 500 nm lateral resolution and ~1 μm axial resolution. In rODT, multiple scattering background is rejected through spatio-temporal gating provided by dynamic speckle-field interferometry, while depth-resolved refractive index maps are reconstructed by developing a comprehensive inverse scattering model that also considers specimen-induced aberration. Benefiting from the high-resolution and full-field quantitative imaging capabilities of rODT, we succeeded in imaging red blood cells and quantifying their membrane fluctuations behind a turbid sample with a thickness of 2.8 scattering mean-free-paths. We further realized volumetric imaging of cornea inside an ex vivo rat eye and quantified its optical properties, including mapping the topography of Dua's and Descemet's membrane surfaces on the nanometer scale. Copyright © 2022, The Authors. All rights reserved.

关键词： Diffraction

来源：评论

学校读者我要写书评

暂无评论

Degradation of Per- and Polyfluoroalkyl Substances in Landfill Leachate by a Thin-Water-Film Nonthermal Plasma Reactor

SSRN

引用

SSRN 2023年

作者： Eeso, Karam Gallan, Rachel Goukeh, Mojtaba Nouri Tate, Kerry Raja, Radha Krishna Bulusu Popovic, Zeljka Abichou, Tarek Chen, Huan Locke, Bruce R. Tang, Youneng Department of Chemical and Biomedical Engineering FAMU-FSU College of Engineering Florida State University 2525 Pottsdamer Street TallahasseeFL32310 United States Department of Civil and Environmental Engineering FAMU-FSU College of Engineering Florida State University 2525 Pottsdamer Street TallahasseeFL32310 United States Chemistry Program Florida Department of Environmental Protection 2600 N Blair Stone Road TallahasseeFL32399 United States National High Magnetic Field Laboratory Florida State University 1800 East Paul Dirac Drive TallahasseeFL32310 United States

Per- and polyfluoroalkyl substances (PFAS) are present in landfill leachate, posing potential challenges to leachate disposal and treatment. This work represents the first study of a thin-water-film nonthermal plasma reactor for PFAS degradation in landfill leachate. Of the 30 PFAS measured in three raw leachates, 21 were above the quantification limits. The removal percentage depended on the category of PFAS. For example, perfluorooctanoic acid PFOA (C8) had the highest removal percentage (77% as an average of the three leachates) of the perfluoroalkyl carboxylic acids (PFCAs) category. The removal percentage decreased when the carbon number increased from 8 to 11 and decreased from 8 to 4. The effects of various landfill leachate components, including sodium chloride, acetate, humic acids, pH, and surfactants, had no or minor impacts ( © 2023, The Authors. All rights reserved.

关键词： Sodium chloride

来源：评论

学校读者我要写书评

暂无评论

DMD Muscle Characteristics in the Time and Frequency Domain

DMD Muscle Characteristics in the Time and Frequency Domain

引用

IEEE Signal Processing in Medicine and Biology Symposium (SPMB)

作者： S. Ahdy R.H. Sandler M Monduy E. Baker J. Wells H.A. Mansy Biomedical Acoustic Research Lab University of Central Florida Orlando Florida USA Mechanical Power Engineering Department Zagazig University Zagazig Egypt Nemours Children's Hospital Orlando Florida USA

ISBN: (纸本)9781665470308

Duchenne muscular dystrophy (DMD) is a lethal muscle degenerative disease affecting 1: 3500 male births [1]. It is caused by genetic mutations resulting in dystrophin protein deficiency. Dystrophin maintains membrane integrity; its deficiency causes myofiber damage under mechanical loading [1]. The resulting DMD muscle membrane tears impact its permeability which increases calcium concentration inside the cell and promotes inflammatory reactions and muscle degeneration [2]. Eventually, DMD muscle suffers a loss of mass, and becomes less functional due to inflammation and fibrosis [3]. Current therapies aim to slow disease progression, promote muscle regeneration and growth, and maintain muscle mass [2].

关键词： Proteins Frequency-domain analysis Degenerative diseases Loading Genetic mutations Medical treatment Muscles

来源：评论

学校读者我要写书评

暂无评论

Site-Specific Quality Assessment of Trabecular Bone Using Highly Nonlinear Solitary Waves

Site-Specific Quality Assessment of Trabecular Bone Using Hi...

引用

European Workshop on Structural Health Monitoring, EWSHM 2020

作者： Kim, Tae-Yeon Yoon, Sangyoung Schiffer, Andreas Jang, In Gwun Lee, Sungmun Civil Infrastructure and Environmental Engineering Khalifa University of Science and Technology Abu Dhabi127788 United Arab Emirates Department of Mechanical Engineering Khalifa University of Science and Technology Abu Dhabi127788 United Arab Emirates The Cho Chun Shik Graduate School of Green Transportation Korea Advanced Institute of Science and Technology Daejeon34051 Korea Republic of Department of Biomedical Engineering Khalifa University of Science and Technology Abu Dhabi127788 United Arab Emirates

ISBN: (纸本)9783030645939

We present a numerical study of highly nonlinear solitary wave interaction with adjacent bone microstructures towards the development of a novel diagnostic scheme for site-specific bone quality assessment. High-resolution finite-element models of the trabecular bone microstructures in the femoral head are generated using a topology optimization-based bone microstructure reconstruction scheme. Using the finite-element models, a hybrid finite-element/discrete-element method is developed to examine the characteristic features of the reflected highly nonlinear solitary waves in a granular chain with adjacent damaged bone microstructure models for the prediction of partial fracture due to the development of osteoporosis. © 2021, Springer Nature Switzerland AG.

关键词： Finite element method

来源：评论

学校读者我要写书评

暂无评论

Improvement in the precision of capillary refill time measurements for diagnosing hypovolemic status

引用

Journal of Biomechanical Science and engineering 2023年第3期18卷

作者： Sugita, Shukei Mizuno, Takato Ujihara, Yoshihiro Nakamura, Masanori Department of Electrical and Mechanical Engineering Nagoya Institute of Technology Gokiso-cho Showa-ku Nagoya466-8555 Japan Center of Biomedical Physics and Information Technology Nagoya Institute of Technology Gokiso-cho Showa-ku Nagoya466-8555 Japan Department of Nanopharmaceutical Sciences Nagoya Institute of Technology Gokiso-cho Showa-ku Nagoya466-8555 Japan

The capillary refill time (CRT) is the time that elapses before the fingernail color returns to red from white after releasing a load applied to the nail. We aimed to estimate hypovolemic status using the CRT. However, the precision of CRT is low. The first step toward improving precision was estimation of the coefficient of variance (CV) via repeated measurements. The best and next-best indices of the CRT change rates in the hypovolemic state were 0.19 and 0.48 respectively, and the corresponding target CVs were ≤ 0.10 and 0.24. The CRTs of subjects were measured by imaging nails during loading and unloading and fitting of an exponential function to the curve of intensity changes. The CRT was 0.77 ± 0.35 s (n = 108), which is comparable to previous studies. However, the CV was 0.37 ± 0.13, which is higher than even the second-best index. Thus, we used only the green color channels of nail images to generate algorithms to define the optimal start time of the CRT calculations;this provided a lower CV (0.31 ± 0.12). Finally, we investigated the effects of fingertip temperature and load release timing on CRT during a cardiac cycle. Correction of the temperature effect with a care on a phase during the cardiac cycle to trigger data collection reduced CV to 0.15 ± 0.11, which cleared the secondbest index. Thus, our protocol improves CRT precision;it may be possible to estimate hypovolemic status using the CRT. © 2023 The Japan Society of mechanical Engineers. This is an open access article under the terms of the Creative Commons Attribution 4.0 International license (https://***/licenses/by/4.0/).

关键词： Exponential functions

来源：评论

学校读者我要写书评

暂无评论

Subchondral Bone Fatigue Injury in the Parasagittal Condylar Grooves of the Distal End of the Third Metacarpal Bone in Thoroughbred Racehorses Elevates Site-Specific Strain Concentration

SSRN

引用

SSRN 2023年

作者： Irandoust, Soroush Whitton, R. Christopher Muir, Peter Henak, Corinne Reid Department of Surgical Sciences School of Veterinary Medicine University of Wisconsin-Madison MadisonWI53706 United States Department of Mechanical Engineering University of Wisconsin-Madison MadisonWI53706 United States Equine Centre Melbourne Veterinary School University of Melbourne WerribeeVIC3030 Australia Department of Biomedical Engineering University of Wisconsin-Madison MadisonWI53706 United States Department of Orthopedics and Rehabilitation University of Wisconsin-Madison MadisonWI53705 United States

Condylar stress fracture of the distal end of the third metacarpal/metatarsal (MC3/MT3) bones is a major cause of Thoroughbred racehorse injury and euthanasia worldwide. Functional adaptation to exercise and fatigue damage lead to structural changes in the subchondral bone that include increased modeling (resulting in sclerotic bone tissue) and targeted remodeling repair (resulting in focal resorption spaces in the parasagittal groove). Whether these focal structural changes, as detectable by standing computed tomography (sCT), lead to elevated strain at the common site of condylar stress fracture has not been demonstrated. Therefore, the goal of the present study was to compare full-field three-dimensional (3D) strain on the distopalmar aspect of MC3 bone specimens with and without focal subchondral bone injury (SBI). Thirteen forelimb specimens were collected from racing Thoroughbreds for mechanical testing ex vivo and underwent sCT. Subsequently, full-field displacement and strain at the joint surface were determined using stereo digital image correlation. Strain concentration was observed in the parasagittal groove (PSG) of the loaded condyles, and those with SBI in the PSG showed higher strain rates in this region than control bones. PSG strain rate in condyles with PSG SBI was more sensitive to CT density distribution in comparison with condyles with no sCT-detectable injury. Findings from this study help to interpret structural changes in the subchondral bone due to fatigue damage and to assess risk of incipient stress fracture in a patient-specific manner. © 2023, The Authors. All rights reserved.

关键词： Image correlation

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：