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SSRN 2023年

作者： Metz, Peter Carl Franz, Cole Kincaid, Joshua Schmitz, Tony Lass, Eric Andrew Babu, Sudarsanam S. Page, Katharine Department of Materials Science and Engineering University of Tennessee KnoxvilleTN37996 United States Department of Mechanical Aerospace and Biomedical Engineering University of Tennessee KnoxvilleTN37996 United States Manufacturing Sciences Division Oak Ridge National Laboratory KnoxvilleTN37932 United States Neutron Scattering Division Oak Ridge National Laboratory Oak RidgeTN37831 United States

Aluminum alloy 6061-T6511 was printed by additive friction stir deposition onto a cast aluminum A206-T4 plate. Metallography, X-ray powder diffraction, X-ray pole figure analysis, and electron backscatter diffraction of the center, advancing side, and retreating side of the 6061 deposit reveals different texture and grain structure characteristics across the transverse direction and through each layer. These distinct microstructural domains are indicative of spatially varied temperature, strain rate, and strain accumulation during deposition, and consequently of regions differing in the fraction of dynamic recovery and dynamic recrystallization during deposition. Hardness mapping over the complete cross section at 0.75 mm resolution shows the alloy continues to age after active deposition, and hardness increases over the 5 mm nearest the final printed layer. Additional mapping at 0.10 mm resolution shows intralayer hardness variations of the deposit on the retreating side. These observations demonstrate that complex and non-uniform thermal-mechanical transients occur during additive friction stir deposition, resulting in spatially non-uniform microstructure and properties. © 2023, The Authors. All rights reserved.

关键词： Additives

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Magnetic Localization for an Intra-abdominal Wireless Laparoscope

Magnetic Localization for an Intra-abdominal Wireless Laparo...

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IEEE International Conference on Robotics and Biomimetics

作者： Hui Liu Ning Li Gregory J. Mancini Jindong Tan Department of Mechanical Aerospace and Biomedical Engineering University of Tennessee Knoxville TN USA Azure Medical Innovation Knoxville TN USA Graduate School of Medicine University of Tennessee Knoxville TN USA

ISBN: (纸本)9781665481106

In single-incision laparoscopic surgery, the mag-netically driven laparoscope is a promising technique to provide larger workspaces and field of view, relief space for other instruments, and require less incision. To apply closed-loop control which guarantees safety and precise motion, a reliable localization is critical during the operation. In this paper, a real-time magnetic localization method is proposed for a wireless magnetically driven laparoscope. Integrated with two pairs of magnets, the robotic laparoscope is shown to have sufficient coupling force to work in a region where the mapping from capsule pose to magnetic field measurement can be accurately expressed by two single dipole models. Combining multiple sensor feedback, the pose of the laparoscope in six degrees of freedom is obtained at 30Hz, while the position and yaw angle are solved based on Newton-Raphson iteration directly without suffering from measurement drift. The average error is 2.9mm in position detection, and below 5.5° for angular motion.

关键词： Laparoscopes Location awareness Wireless communication Wireless sensor networks Magnetic field measurement Position measurement Robot sensing systems

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Study of the Spike (S) glycoprotein from the SARSCoV-2 as a possible source of translocating peptides of biomedical interest

Study of the Spike (S) glycoprotein from the SARSCoV-2 as a ...

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2020 AIChE Annual Meeting

作者： Henao, Maria C. Ocasión, Camila Yepes, Arnovis Burgos, Juan C. Reyes, Luis H. Cruz, Juan C. Department of Chemical and Food Engineering Universidad de los Andes Bogotá Colombia Physical Sciences Program Universidad de Cartagena Cartagena Colombia Chemical Engineering Program Universidad de Cartagena Cartagena Colombia Department of Biomedical Engineering Universidad de los Andes Bogotá Colombia

ISBN: (纸本)9780816911141

Membranes are natural selective barriers necessary for the correct function of human cells as they control the entry of diverse molecules into the intracellular space. Although small and polar molecules such as amino acids and ions cancome across the membrane through channels, larger macromolecules such as proteins and nucleic acids generally failto do so. This represents a significant obstacle for efficient intracellular drug delivery, which is essential to increase the bioavailability of pharmacological agents for the treatment of numerous diseases. Commonly, diverse methods havebeen studied to mediate the uptake of large molecules, including mechanical and electrical transfection techniques,but also viral carrier systems. Some of these methods have been successfully tested in vitro but exhibit biosafety and cytotoxicity issues. Inconsequence, there is an increasing interest in the development of novel delivery methods with low cytotoxicity butalso high transduction efficiency. An attractive alternative is the cell-penetrating peptides (CPPs), which can beobtained from different origins including signal peptides, viral proteins, or antimicrobial peptides. CPPs are generallyshort peptides with lengths between 5-30 amino acids, positively charged or amphipathic, and rich in arginine andlysine. Due to their ability to intermingle with the phospholipids of membrane bilayers, some CPPs are able toundergo translocation, and consequently can be considered as promising candidates for the delivery of biologically active molecules to cells. The novel coronavirus SARS-CoV-2 has attracted significant attention over the past few months as it is responsible forthe current global sanitary emergency where more than 1.3 M cases have been confirmed and over 70,000 peoplehave died. The Spike (S) glycoprotein has been thought to be responsible as the major determinant of the viraltropism towards human cells. This protein has a 180 kDa molecular weight and is displayed at the viral su

关键词： Coronavirus

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Polarized Superradiance from CsPbBr3 Quantum Dot Superlattice with Controlled Inter-dot Electronic Coupling

arXiv

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arXiv 2024年

作者： Luo, Lanyin Tang, Xueting Park, Junhee Wang, Chih-Wei Park, Mansoo Khurana, Mohit Singh, Ashutosh Cheon, Jinwoo Belyanin, Alexey Sokolov, Alexei V. Son, Dong Hee Department of Physics and Astronomy Texas A&M University College StationTX77843 United States Institute of Quantum Science and Engineering Texas A&M University College StationTX77843 United States Department of Chemistry Texas A&M University College StationTX77843 United States Center for Nanomedicine Institute for Basic Science and Graduate Program of Nano Biomedical Engineering Advanced Science Institute Yonsei University Seoul03722 Korea Republic of

Cooperative emission of photons from an ensemble of quantum dots (QDs) as superradiance can arise from the electronically coupled QDs with a coherent emitting excited state. This contrasts with superfluorescence (Dicke superradiance), where the cooperative photon emission occurs via a spontaneous buildup of coherence in an ensemble of incoherently excited QDs via their coupling to a common radiation mode. While superfluorescence has been observed in perovskite QD systems, reports of superradiance from the electronically coupled ensemble of perovskite QDs are rare. Here, we demonstrate the generation of polarized superradiance with a very narrow linewidth ( © 2024, CC BY-NC-ND.

关键词： Perovskite

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Blockchain and Machine Learning For Predictive Analytics in Customer Relationship Management

Blockchain and Machine Learning For Predictive Analytics in ...

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International Conference on ICT in Business Industry & Government (ICTBIG)

作者： Jatin Khurana Santhosh Kumar. C Ashmeet Kaur Anila Bajpai Monali Ravindra Borade N. Kalidas Centre of Research Impact and Outcome Chitkara University Rajpura Punjab India Department of Civil Prince Shri Venkateshwara Padmavathy Engineering College Chennai Chitkara Centre for Research and Development Chitkara University Himachal Pradesh India Program Manager School of Mangement - UG Management JAIN (Deemed to be University) Bangalore Karnataka India AI & Ds Vishwakarma Institute of Technology Pune India Department of Mechanical Engineering Karpagam Academy of Higher Education Coimbatore

ISBN: (数字)9798331518981

ISBN: (纸本)9798331518998

CRM strengthens customer relationships in today's fast-paced corporate land-scape. This paper examines a novel strategy that integrates RNN, Deep Learning, and NLP with Blockchain-Enhanced Customer Relationship Management. This relationship might help firms foresee consumer needs, engage with them, and protect their data, improving CRM. Blockchain CRM (BCRM) secures and simplifies data. Trust and transparency are encouraged while customer data is protected. Deep learning algorithms make it simpler to segment clients and customize offerings. Time-series analysis using machine learning algorithms like RNN predicts client behavior accurately. NLP helps firms understand client feedback by analyzing reviews and comments. Our testing revealed RNN, NLP, and Deep Learning performed better. NLP was flawless, RNN right, and Deep Learning superior. These findings illustrate that the offered solutions may accommodate many corporate objectives and duties. Our graphics helped firms identify the optimal algorithm for CRM enhancement initiatives by comparing them. In predictive analytics accuracy, data security, speed, customization, and rule compliance, the BCRM approach using blockchain and machine learning outperforms CRM alternatives. It provides firms a competitive advantage in maintaining and strengthening customer connections, creating trust, and driving growth and success in a data-driven world.

关键词： Deep learning Machine learning algorithms Accuracy Data security Time series analysis Smart contracts Customer relationship management Prediction algorithms Blockchains Predictive analytics

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Renderable Street View Map-Based Localization: Leveraging 3D Gaussian Splatting for Street-Level Positioning

Renderable Street View Map-Based Localization: Leveraging 3D...

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IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)

作者： Howoong Jun Hyeonwoo Yu Songhwai Oh Artificial Intelligence (IPAI) Seoul National University and Automation and Systems Research Institute (ASRI) and Sequor Robotics Inc. Seoul Korea Republic of Department of Intelligent Robotics & Mechanical Engineering Sungkyunkwan University (SKKU) Suwon-si Korea Republic of Department of Electrical and Computer Engineering (ECE) & Interdisciplinary Program in Artificial Intelligence (IPAI) Seoul National University and Automation and Systems Research Institute (ASRI) and Sequor Robotics Inc. Seoul Korea Republic of

ISBN: (数字)9798350377705

ISBN: (纸本)9798350377712

In this paper, we introduce a new method that first utilizes 3D Gaussian splatting in street-level localization problem. Robust localization with street-level real-world images such as street view is a major issue for autonomous vehicle, augmented reality (AR) navigation, and outdoor mobile robots. The objective is to determine the position and orientation of a query image that matches a street view database composed of RGB images. However, given the limited information available in the street view images, accurately determining the location solely based on this data presents a significant challenge. To address this challenge, we propose a novel method called renderable street view map-based localization (RSM-Loc). This approach enhances the localization process by augmenting 2D street view images into a renderable 3D map using 3D Gaussian splatting, to resolve street-level localization problems. Upon receiving a query RGB image without geometry information, the proposed method renders 2D images from a pre-made renderable map and compares image pose similarities between the rendered images and the query image. Through iterations of this process, the proposed method eventually estimates the pose of the given query image. The experimental results demonstrate that RSM-Loc outperforms the baselines with neural-field-based localization. Additionally, we conduct deep analysis on the proposed method to show that our method can serve as a new concept for the street-level localization problem.

关键词： Location awareness Visualization Matched filters Three-dimensional displays Image resolution Navigation Noise measurement Mobile robots Intelligent robots Image reconstruction

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Enhancing Mucus Clearance by Cough through Repeated Pulses

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Journal of engineering and Science in Medical Diagnostics and Therapy 2020年第3期3卷 031004页

作者： Tuna, Duygu L. Ünal, Mehmet Altay Arl, Fikret Krumpe, Peter Evrensel, Cahit A. Department of Physics College of Science Ankara University Ankara06830 Turkey Department of Physics Engineering College of Engineering Ankara University Ankara06560 Turkey Department of Electrical and Electronics Engineering College of Engineering Ankara University Ankara06830 Turkey VA Medical Center RenoNV89502 United States Department of Biomedical Engineering College of Engineering Ankara06830 Turkey Physics Group College of Engineering Atılım University Ankara06830 Turkey School of Medicine University of Nevada RenoNV89557 United States Department of Mechanical Engineering College of Engineering University of Nevada RenoNV89557 United States

The aim of this study is to investigate the potential increase in the efficiency of the mucus clearance by repeated pulses of the same maximum speed and total air volume compared to single pulse simulated cough and to explore the effect of mucus simulant rheology and duration between repeated pulses on it. Experiments are conducted to study the behavior and clearance of a mucus simulant through a D-shaped rigid plexiglass horizontal tracheal model by approximately rectangular pulses. Mucus simulants with viscoelastic properties like mucus of patients with chronic obstructive pulmonary disease (COPD) or similar illnesses, a moderate increase in elastic modulus, and a sharp decrease in viscosity with increasing frequency were prepared by locust bean gum and borax-de-ionized water solutions (Ragavan, A. J., Evrensel, C. A., and Krumpe, P., 2010, "Interactions of Airflow Oscillation, Tracheal Inclination, and Mucus Elasticity Significantly Improve Simulated Cough Clearance," Chest, 137(2), pp. 355-361). Displacement of 0.3 ml mucus simulant aliquot is measured during single or repeated airflow pulses with a total air volume of about 1.1 L and the same maximum velocity. The desired flow pattern is generated by a compressor set at 4.5 bar and a computer-controlled on-off valve. Displacement of the same volume of mucus aliquot increases with the increasing number of pulses with the same total volume of air and maximum velocity and increasing of elasticity of mucus simulants. The increased maximum airflow velocity of repeated pulses affects the displacement of mucus aliquot positively. Moreover, when the duration length between the repeated pulses increased up to 100 ms, the displacement of aliquot increased up to but after 100 ms to 150 ms started to decrease. © 2020 American Society of mechanical Engineers (ASME). All rights reserved.

关键词： Air

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Development of low-cost tool for assessing chlorophyll content using the mobile-phone camera

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AIP Conference Proceedings 2024年第1期3086卷

作者： Wahyu Nurkholis Hadi Syahputra Chatchawan Chaichana Ramnarong Wanison Braja Manggala Graduate Master’s Degree Program in Energy Engineering Department of Mechanical Engineering Faculty of Engineering Chiang Mai University Chiang Mai 50200 Thailand Energy Technology for Environment Research Center Department of Mechanical Engineering Faculty of Engineering Chiang Mai University Chiang Mai 50200 Thailand Department of Mechanical Engineering Faculty of Engineering Chiang Mai University Chiang Mai 50200 Thailand

Leaves can be used to assess the health of a plant. The chlorophyll content and nitrogen status of plants might be used to assess plant health. Chlorophyll content of plant leaves is measurable in the laboratory using dimethyl sulfoxide or the Kjeldahl technique. These destructive investigations of plant tissues accurately evaluates chlorophyll concentration and nitrogen status. However, this procedure is costly and time-consuming. Using a SPAD instrument, non-destructive chlorophyll measurements were performed. However, the price of the instrument is high. This research intends to develop a technique for detecting chlorophyll content using a smartphone’s built-in camera. The approach used is an advancement of ground-based remote sensing technology. The object of this research is maize. An RGB camera on a mobile phone was used to gather data on the greenness level of the leaf. Concurrently, the SPAD value was measured to determine the chlorophyll content. In this study, there were three primary phases, capturing leaf images with geotags, leaf image processing, and vegetation index (VIs) analysis. This research demonstrated that a mobile camera has potential as a tool for measuring chlorophyll content depending on the level of leaf greenness. Additionally, the GPS function on each data provides the chlorophyll distribution in a field.

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Dynamics Study of Constant DI and Constant TR Control for Cardiac Alternans Based on a Two Dimensional Cellular Automata Model

Research Square

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Research Square 2021年

作者： Xiong, Min Sun, Kai Su, Xiaowen Tolkacheva, Elena G. Zhao, Xiaopeng Department of Electrical Engineering and Computer Science University of Tennessee Knoxville Tickle College of Engineering KnoxvilleTN United States Department of Mechanical Aerospace and Biomedical Engineering University of Tennessee KnoxvilleTN United States Department of Biomedical Engineering University of Minnesota Twin Cities Campus MinneapolisMN United States

As a precursor for cardiac arrhythmias such as atrial and ventricular fibrillations, which could cause sudden cardiac death (SCD), cardiac alternans is essentially an unstable heart rhythm with alternating long and short action potential durations (APD) of cardiac myocytes that usually occurs under fast pacing conditions. In this paper, the constant TR control method based on global pseudo-electrocardiogram (ECG) is studied and compared with the local constant diastolic interval (DI) control method using a 2-dimensional (2-D) cellular automata model (CAM), aiming at preventing or eliminating cardiac alternans before arrhythmias. The results show that both the constant TR and constant DI control methods are effective in stabling the alternans to a smaller basic cycle length (BCL). Also, the efficacy of the two control approaches depends on the "decrease step" Δ in the downsweep protocol, and a smaller Δ could significantly improve their performance. Besides, in general, constant TR control is superior to constant DI control in alternans prevention when a relatively large Δ is adopted. © 2021, CC BY.

关键词： Electrocardiograms

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Investigation of optical coherence tomography imaging in nylon 12 powder 28

Investigation of optical coherence tomography imaging in nyl...

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28th Annual International Solid Freeform Fabrication Symposium - An Additive Manufacturing Conference, SFF 2017

作者： Lewis, Adam Katta, Nitesh McElroy, Austin Milner, Thomas Fish, Scott Beaman, Joseph McKetta Department of Chemical Engineering Cockrell School of Engineering University of Texas at Austin AustinTX78705 United States Department of Biomedical Engineering Cockrell School of Engineering University of Texas at Austin AustinTX78705 United States Department of Mechanical Engineering Cockrell School of Engineering University of Texas at Austin AustinTX78705 United States

Optical Coherence Tomography (OCT) has shown promise as a new process sensor in selective laser sintering (SLS) which can yield depth resolved data not attainable with conventional sensors. However, OCT images of nylon 12 SLS parts and powder contain artifacts, which have not been previously investigated in literature. These artifacts along with the highly scattering nature of the SLS parts and powder limit the imaging depth, which decreases the usefulness of OCT imaging. This study seeks to study the causes of the imaging artifacts and proposes and investigates methods to improve OCT imaging depth in nylon 12 powder. Copyright © SFF *** rights reserved.

关键词： Optical tomography

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