检索结果-内蒙古大学图书馆

Oversized Conduits Predict Stenosis in Tissue Engineered Vascular Grafts

JACC: Basic to Translational Science 2025年

作者： Blum, Kevin M. Turner, Mackenzie E. Schwarz, Erica L. Best, Cameron A. Kelly, John M. Yates, Andrew R. Hor, Kan N. Matsuzaki, Yuichi Drews, Joseph D. Zakko, Jason Shah, Kejal Shinoka, Toshiharu Humphrey, Jay D. Marsden, Alison L. Breuer, Christopher K. Center for Regenerative Medicine The Abigail Wexner Research Institute Nationwide Children's Hospital Columbus OH United States Department of Biomedical Engineering The Ohio State University Columbus OH United States Department of Molecular Cellular and Developmental Biology The Ohio State University Columbus OH United States Biomedical Sciences Graduate Program The Ohio State University College of Medicine Columbus OH United States Department of Pediatrics and Bioengineering Stanford University Stanford CA United States Department of Biomedical Engineering Yale University New Haven CT United States Department of Pediatric Cardiology Nationwide Children's Hospital Columbus OH United States Department of Surgery The Ohio State University Wexner Medical Center Columbus OH United States Department of Surgery Nationwide Children's Hospital Columbus OH United States

Tissue-engineered vascular grafts (TEVGs) offer promising advancements in treating congenital heart disease by enabling the creation of autologous tissue for complex cardiac repairs. Our approach involves implanting biodegradable scaffolds seeded with autologous cells that remodel into functional neovessels. To understand better the factors guiding neovessel formation, we evaluated 50 ovine thoracic TEVGs using angiography at 1 and 6 weeks postimplantation. Nondimensionalization accounted for anatomical differences between animals and identified hemodynamics and surgical sizing as potential driving factors. Regression analysis revealed that narrowing at the inflow anastomosis and graft oversizing correlated significantly with stenosis development. Computational fluid dynamics showed that these factors influenced wall shear stress and flow patterns, contributing to neovessel narrowing. Comparisons with clinical trial data from Fontan conduits supported these findings, emphasizing that matching graft size to the native inflow vessel can reduce stenosis and enhance TEVG performance. © 2025 The Authors

关键词： computational fluid dynamics oversizing stenosis tissue engineered vascular graft

来源：评论

学校读者我要写书评

暂无评论

Magnetically induced micropillar arrays for an ultrasensitive flexible sensor with a wireless recharging system

引用

Science China Materials 2021年第8期64卷 1977-1988页

作者： Libo Gao Ying Han James Utama Surjadi Ke Cao Wenzhao Zhou Hongcheng Xu Xinkang Hu Mingzhi Wang Kangqi Fan Yuejiao Wang Weidong Wang Horacio D.Espinosa School of Mechano-Electronic Engineering Xidian UniversityXi’an 710071China CityU-Xidian Joint Laboratory of Micro/Nano-Manufacturing Shenzhen 518057China Nano-Manufacturing Laboratory(NML) Shenzhen Research Institute of City University of Hong KongShenzhen 518057China Department of Mechanical Engineering City University of Hong KongKowloon 999077Hong Kong SARChina Department of Mechanical Engineering Northwestern UniversityEvanstonIllinois 60208USA Theoretical and Applied Mechanics Program Northwestern UniversityEvanstonIllinois 60208USA

Significant efforts have been devoted to enhancing the sensitivity and working range of flexible pressure sensors to improve the precise measurement of subtle variations in pressure over a wide detection spectrum. However,achieving sensitivities exceeding 1000 kPa^(-1) while maintaining a pressure working range over 100 kPa is still challenging because of the limited intrinsic properties of soft matrix materials. Here, we report a magnetic field-induced porous elastomer with micropillar arrays(MPAs) as sensing materials and a well-patterned nickel fabric as an electrode. The developed sensor exhibits an ultrahigh sensitivity of 10,268 kPa^(-1)(0.6–170 kPa) with a minimum detection pressure of 0.25 Pa and a fast response time of 3 ms because of the unique structure of the MPAs and the textured morphology of the electrode. The porous elastomer provides an extended working range of up to 500 kPa with long-time durability. The sophisticated sensor system coupled with an integrated wireless recharging system comprising a flexible supercapacitor and inductive coils for transmission achieves excellent performance. Thus, a diverse range of practical applications requiring a low-to-high pressure range sensing can be developed. Our strategy, which combines a microstructured high-performance sensor device with a wireless recharging system, provides a basis for creating next-generation flexible electronics.

关键词： high sensitivity pressure sensor supercapacitor wireless recharging flexible electronics

来源：评论

学校读者我要写书评

暂无评论

Excessive Pallidal Beta-Band Activity & Functional Connectivity: A Novel Intracranial Biomarker of Status Dystonicus

引用

Brain Stimulation 2025年第1期18卷 539-540页

作者： Balachandar, Arjun Vogt, Lindsey Mithani, Karim Coleman, Sebastian Leblanc-Miller, Andrea Breitbart, Sara Fasano, Alfonso Gorodetsky, Carolina Ibrahim, George The Hospital for Sick Children Canada University of Toronto Canada Krembil Research Institute Canada The Edmond J Safra Program in Parkinson's Disease and Morton and Gloria Shulman Movement Disorders Clinic Canada Toronto Western Hospital Canada The Hospital for Sick Children Department of Paediatrics Canada Division of Neurology SickKids hospital Toronto Canada Canada University of Toronto Institute of Biomedical Engineering Canada Division of Neurosurgery Hospital for Sick Children Department of Surgery University of Toronto Canada

来源：评论

学校读者我要写书评

暂无评论

Wrist-Squeezing Force Feedback Improves Accuracy and Speed in Robotic Surgery Training

arXiv

引用

arXiv 2022年

作者： Machaca, Sergio Cao, Eric Chi, Amy Adrales, Gina Kuchenbecker, Katherine J. Brown, Jeremy D. The Department of Biomedical Engineering Johns Hopkins University BaltimoreMD21218 United States The Department of Mechanical Engineering Johns Hopkins University BaltimoreMD21218 United States The Johns Hopkins University School of Medicine BaltimoreMD21205 United States The Max Planck Institute for Intelligent Systems Stuttgart Germany

Current robotic minimally invasive surgery (RMIS) platforms provide surgeons with no haptic feedback of the robot's physical interactions. This limitation forces surgeons to rely heavily on visual feedback and can make it challenging for surgical trainees to manipulate tissue gently. Prior research has demonstrated that haptic feedback can increase task accuracy in RMIS training. However, it remains unclear whether these improvements represent a fundamental improvement in skill, or if they simply stem from re-prioritizing accuracy over task completion time. In this study, we provide haptic feedback of the force applied by the surgical instruments using custom wrist-squeezing devices. We hypothesize that individuals receiving haptic feedback will increase accuracy (produce less force) while increasing their task completion time, compared to a control group receiving no haptic feedback. To test this hypothesis, N=21 novice participants were asked to repeatedly complete a ring rollercoaster surgical training task as quickly as possible. Results show that participants receiving haptic feedback apply significantly less force (0.67 N) than the control group, and they complete the task no faster or slower than the control group after twelve repetitions. Furthermore, participants in the feedback group decreased their task completion times significantly faster (7.68%) than participants in the control group (5.26%). This form of haptic feedback, therefore, has the potential to help trainees improve their technical accuracy without compromising speed. Copyright © 2022, The Authors. All rights reserved.

关键词： Robotic surgery

来源：评论

学校读者我要写书评

暂无评论

3D Printed Biomimetic Flexible Blood Vessels with IPS Cell-Laden Hierarchical Multilayers

SSRN

引用

SSRN 2022年

作者： Hann, Sung Yun Cui, Haitao Chen, Guibin Boehm, Manfred Zhang, Lijie Grace Department of Mechanical and Aerospace Engineering The George Washington University WashingtonDC20052 United States BethesdaMD20892 United States Department of Electrical and Computer Engineering The George Washington University WashingtonDC20052 United States Department of Biomedical Engineering The George Washington University WashingtonDC20052 United States Department of Medicine The George Washington University Medical Center WashingtonDC20052 United States

Successful recovery from vascular diseases has relied on the repair of damaged blood vessels (BVs), and most of the current approaches involve the implantation of autologous BVs, which critically suffers from the shortage of donors. Researchers have attempted to develop artificial vessels as an alternative solution. However, the manufacturing of small-diameter ( © 2022, The Authors. All rights reserved.

关键词： 3D printers

来源：评论

学校读者我要写书评

暂无评论

Multi-Material, Approach-Guided, Controlled-Resolution Breast Meshing for Fe-Based Interactive Surgery Simulation

Multi-Material, Approach-Guided, Controlled-Resolution Breas...

引用

Annual Modeling and Simulation Conference (ANNSIM)

作者： Motaz Alqaoud John Plemmons Eric Feliberti Krishnanand Kaipa Gabor Fichtinger Yiming Xiao Tanweer Rashid Michel Audette Biomedical Engineering Old Dominion University Norfolk VA USA Department of Radiology Eastern Virginia Medical School Norfolk VA USA Department of Surgery Eastern Virginia Medical School Norfolk VA USA Mechanical & Aerospace Engineering Old Dominion University Norfolk VA USA School of Computing Queen’s University Kingston ON Canada Computer Science & Software Engineering Concordia University Montreal QC Canada Neuroimage Analytics Laboratory University of Texas Health Science Center San Antonio TX USA Computational Modeling & Simulation Engineering Old Dominion University Norfolk VA USA

This paper proposes a guided, controlled resolution framework for 3D multi-material meshing. Using data from magnetic resonance (MR) images, we efficiently focused on demonstrating our framework for patient-specific breast cases. As a result, we can preserve the shared boundaries and enhance the resolution without negating the aspect of simulation computing time needed for finite element analysis (FEA). Our output is a high-quality volumetric mesh comprising 21K cells representing the three main parts for breast surgery simulation and planning, fat, fibroglandular (FGT), and tumor mass. Our approach combines three steps, surface meshing, surface mesh decimation, and generating a volumetric mesh. We showed experimental results for every stage and compared our final output to other literature, proving our method's efficiency in an accurate, simple, and high-quality presentation of a patient-specific breast meshing.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Know-Need-Do-Problem Based Learning (KND-PBL) in programming course: Is it effective?

引用

AIP Conference Proceedings 2024年第1期3199卷

作者： Rizky Ema Wulansari Rizki Hardian Sakti Primawati Primawati Sri Rizki Putri Primandari Jasman Jasman Yufrizal Yufrizal Irzal Irzal Department of Mechanical Engineering Faculty of Engineering Universitas Negeri Padang 25171 Padang Sumatera Barat Indonesia TVE Postgraduate Program Faculty of Engineering Universitas Negeri Padang 25171 Padang Sumatera Barat Indonesia Design Engineering Laboratory Department of Mechanical Engineering Faculty of Engineering Universitas Negeri Padang 25171 Padang Sumatera Barat Indonesia

This study aimed at developing the Know-Need-Do-Problem Based Learning (KND-PBL) model and evaluate its effectiveness in a programming course. The focus of this research was to address the problem of suboptimal implementation of the case method in programming education. The research methodology employed in this study was research and development, involving 60 students and 15 experts as participants. The data collected were analyzed using mean and path analysis methods. The results of the study demonstrate that the development of the new PBL model called KND-PBL in programming course successfully enhances students’ problem-solving skills and learning outcomes. Through the KND-PBL approach, students were able to develop their understanding of programming concepts by acquiring foundational knowledge (Know), understanding the need to apply these concepts (Need), engaging in activities that require the application of concepts (Do), and facing problem-solving challenges relevant to the learning material (Problem Based Learning). This research provided evidence that the implementation of KND-PBL in programming course brought significant benefits to students. The model helped improve students’ problem-solving skills and learning outcomes, which were important goals in a programming course. The implications of this study highlight the importance of integrating the KND-PBL approach in the design of programming course to optimize learning outcomes.

关键词：

来源：评论

学校读者我要写书评

暂无评论

SHARM: Segmented Head Anatomical Reference Models

arXiv

引用

arXiv 2023年

作者： Rashed, Essam A. Al-Shatouri, Mohammad Laakso, Ilkka Hirata, Akimasa Graduate School of Information Science University of Hyogo Kobe650-0047 Japan Radiology Department Faculty of Medicine Suez Canal University Ismailia41522 Egypt Department of Electrical Engineering and Automation Aalto University Espoo Finland Aalto neuroimaging Aalto University Espoo Finland Department of Electrical and Mechanical Engineering Nagoya Institute of Technology Nagoya466-8555 Japan Center of Biomedical Physics and Information Technology Nagoya Institute of Technology Nagoya466-8555 Japan

Reliable segmentation of anatomical tissues of human head is a major step in several clinical applications such as brain mapping, surgery planning and associated computational simulation studies. Segmentation is based on identifying different anatomical structures through labeling different tissues through medical imaging modalities. The segmentation of brain structures is commonly feasible with several remarkable contributions mainly for medical perspective;however, non-brain tissues are of less interest due to anatomical complexity and difficulties to be observed using standard medical imaging protocols. The lack of whole head segmentation methods and unavailability of large human head segmented datasets limiting the variability studies, especially in the computational evaluation of electrical brain stimulation (neuromodulation), human protection from electromagnetic field, and electroencephalography where non-brain tissues are of great importance. To fill this gap, this study provides an open-access Segmented Head Anatomical Reference Models (SHARM) that consists of 196 subjects. These models are segmented into 15 different tissues;skin, fat, muscle, skull cancellous bone, skull cortical bone, brain white matter, brain gray matter, cerebellum white matter, cerebellum gray matter, cerebrospinal fluid, dura, vitreous humor, lens, mucous tissue and blood vessels. The segmented head models are generated using open-access IXI MRI dataset through convolutional neural network structure named ForkNet+. Results indicate a high consistency in statistical characteristics of different tissue distribution in age scale with real measurements. SHARM is expected to be a useful benchmark not only for electromagnetic dosimetry studies but also for different human head segmentation applications. © 2023, CC BY.

关键词： Convolution

来源：评论

学校读者我要写书评

暂无评论

An Open-Source Robotic Chinese Chess Player

An Open-Source Robotic Chinese Chess Player

引用

IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS)

作者： Shan An Guangfu Che Jinghao Guo Yanjie Xu Guoxin Wang Konstantinos A. Tsintotas Fukai Zhang Junjie Ye Changhong Fu Haogang Zhu Hong Zhang JD Health International Inc. Beijing China *** Inc Beijing China Puncture (Shanghai) Intelligent Medical Technology Co. Ltd Shanghai China College of Biomedical Engineering & Instrument Science Zhejiang University Hangzhou China Department of Production and Management Engineering Democritus University of Thrace Xanthi Greece Citrus Research Institute Southwest University Chongqing China School of Mechanical Engineering Tongji University Shanghai China State Key Laboratory of Software Development Environment Beihang University Beijing China Department of Electronic and Electrical Engineering Southern University of Science and Technology Shenzhen China

Consumer robots can accompany children growing up, improving their abilities while playing and entertaining. This paper presents an open-source, practical, low-cost robotic Chinese chess player. The proposed system includes an elaborate mechanical structure, a simple kinematic solution, a novel robot operating system, real-time and accurate chess recognition. Regarding its mechanical design, it combines a magnetism structure and mechanical cam drive, while the overall system has just three servo motors. At the same time, its control strategy is simple and effective. Furthermore, a lightweight robot message communication mechanism, entitled TinyROS, is developed for computing resource-limited embedded chips. Concerning the recognition process, our CNNbased object detector determines chess and achieves accurate identification. As a result, our robotic Chinese chess player is exquisite and easy for large-scale promotion while improving users' chess skills. Aiming to facilitate future consumer robot research and popularize customer robots, the model's mechanical and software design and the TinyROS protocol are open-sourced at https://***/Star-Robot/chinese-chess-robot.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Onset of visible capillary waves from high-frequency acoustic excitation

arXiv

引用

arXiv 2022年

作者： Zhang, Shuai Orosco, Jeremy Friend, James Medically Advanced Devices Laboratory Center for Medical Device Engineering and Biomechanics Department of Mechanical and Aerospace Engineering Jacobs School of Engineering University of California La Jolla San DiegoCA92093-0411 United States Materials Science and Engineering Program Jacobs School of Engineering University of California La Jolla San DiegoCA92093-0411 United States Department of Surgery School of Medicine University of California La Jolla San DiegoCA92093 United States

Remarkably, the interface of a fluid droplet will produce visible capillary waves when exposed to acoustic waves. For example, a small (∼ 1 µL) sessile droplet will oscillate at a low ∼ 102 Hz frequency when weakly driven by acoustic waves at ∼ 106 Hz frequency and beyond. We measured such a droplet's interfacial response to 6.6 MHz ultrasound to gain insight into the energy transfer mechanism that spans these vastly different timescales, using high-speed microscopic digital transmission holography, a unique method to capture three-dimensional surface dynamics at nanometer space and microsecond time resolutions. We show that low-frequency capillary waves are driven into existence via a feedback mechanism between the acoustic radiation pressure and the evolving shape of the fluid interface. The acoustic pressure is distributed in the standing wave cavity of the droplet, and as the shape of the fluid interface changes in response to the distributed pressure present on the interface, the standing wave field also changes shape, feeding back to produce changes in the acoustic radiation pressure distribution in the cavity. A physical model explicitly based upon this proposed mechanism is provided, and simulations using it were verified against direct observations of both the microscale droplet interface dynamics from holography and internal pressure distributions using microparticle image velocimetry. The pressure-interface feedback model accurately predicts the vibration amplitude threshold at which capillary waves appear, the subsequent amplitude and frequency of the capillary waves, and the distribution of the standing wave pressure field within the sessile droplet responsible for the capillary waves. © 2022, CC BY-NC-ND.

关键词： Pressure distribution

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：