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Reinforced conductive polyester based on itaconic acids, glycerol and polypyrrole with potential for electroconductive tissue restoration

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Synthetic Metals 2023年 293卷

作者： Ghaffari-Bohlouli, Pejman Golbaten-Mofrad, Hooman Najmoddin, Najmeh Goodarzi, Vahabodin Shavandi, Amin Chen, Wei-Hsin Applied Biotechnology Research Center Baqiyatallah University of Medical Sciences Tehran Iran École polytechnique de Bruxelles 3BIO-BioMatter Avenue F.D. Roosevelt 50 - CP 165/61 Brussels1050 Belgium School of Chemical Engineering College of Engineering University of Tehran Tehran Iran Department of Biomedical Engineering Science and Research Branch Islamic Azad University Tehran Iran Department of Aeronautics and Astronautics National Cheng Kung University Tainan701 Taiwan Research Center for Smart Sustainable Circular Economy Tunghai University Taichung407 Taiwan Department of Mechanical Engineering National Chin-Yi University of Technology Taichung411 Taiwan

Modified chemically crosslinked polyesters as soft and electroconductive materials have investigated for tissue engineering applications. In this work, electroconductivity, thermal stability, and mechanical properties of synthesized Poly (glycerol-sebacate-itaconic) (PGSIT) by the solvent-free method was studied by incorporating polypyrrole (PPy) and clay within the PGSIT matrix. Hydrogen bonds between PGSIT and PPy lead to a homogeneous dispersion of clay and PPy within the PGSIT matrix. The evaluations indicated that PPy and clay could raise the conductivity of PGSIT from 5.9 × 10−11 S/cm to 1.4 × 10−4 S/cm, Young's modulus from 0.19 MPa to 0.9 MPa, tensile strain to 0.91 MPa from 0.25 MPa, and improved the thermal stability and hydrophilicity of the matrix. The PGSIT-PPy-clay composite might have the potential as electroconductive bio-elastomer in tissue engineering applications. © 2022 Elsevier B.V.

关键词： Glycerol

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ezyMRI: How to build an MRI machine from scratch - Experience from a four-day hackathon

arXiv

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arXiv 2024年

作者： Huang, Shaoying Algarín, José Miguel Alonso, Joseba Anieyrudh, R. Borreguero, Jose Bschorr, Fabian Cassidy, Paul Choo, Wei Ming Corcos, David Guallart-Naval, Teresa Han, Heng Jing Igwe, Kay Chioma Kang, Jacob Li, Joe Littin, Sebastian Liu, Jie Rodriguez, Gonzalo Gabriel Solomon, Eddy Tan, Li-Kuo Tian, Rui Webb, Andrew Weber, Susanna Xiao, Dan Xu, Minxuan Yu, Wenwei Zhang, Zhiyong Zinghini, Isabelle Blümich, Bernhard Singapore University of Technology and Design Singapore Instituto de Instrumentación para Imagen Molecular Valencia Spain Department of Internal Medicine II University Ulm Medical Center Ulm Germany Singapore Engineering Product Development Singapore University of Technology and Design Singapore Agile MRI ltd Tel Aviv Israel Department of Biomedical Engineering Columbia University New York United States Jiangsu LiCi Medical Device Co. Ltd China Division of Medical Physics Department of Diagnostic and Interventional Radiology University Medical Center Freiburg Faculty of Medicine University of Freiburg Freiburg Germany NingBo ChuanShanJia Electrical and Mechanical Co. Ltd China Max-Planck Institute for Multidisciplinary Sciences Göttingen Germany Weill Cornell Medical College New YorkNY United States Department of Biomedical Imaging Faculty of Medicine Universiti Malaya Malaysia High-Field MR center Max Planck Institute for Biological Cybernetics Tübingen Germany Leids Universitair Medisch Centrum Leiden University Leiden Netherlands Department of Physics University of Windsor WindsorON Canada Department of Electrical and Computer Engineering College of Design and Engineering National University of Singapore Singapore Center for Frontier Medical Engineering Chiba University Chiba Japan School of Biomedical Engineering Shanghai Jiao Tong University China Institut für Technische und Makromolekulare Chemie RWTH Aachen University Aachen Germany

Nuclear magnetic resonance instruments are becoming available to the do-it-yourself community. The challenges encountered in the endeavor to build a magnetic resonance imaging instrument from scratch were confronted in a four-day hackathon at Singapore University of Technology and Design in spring 2024. One day was devoted to educational lectures and three days to system construction and testing. Seventy young researchers from all parts of the world formed six teams focusing on magnet, gradient coil, RF coil, console, system integration, and design, which together produced a working MRI instrument in three days. The different steps, encountered challenges, and their solutions are reported. Copyright © 2024, The Authors. All rights reserved.

关键词： Nuclear magnetic resonance

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#7. Downstream effects of Gli2 targeting on tumor-immune cell crosstalk in bone metastatic breast cancer

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Journal of Bone Oncology 2024年 45卷 100545-100545页

作者： Bennett, Natalie Rhoades, Julie Vanderbilt Program in Cancer Biology Vanderbilt Medical Scientist Training Program Department of Veterans Affairs USA Vanderbilt Program in Cancer Biology Department of Veterans Affairs Vanderbilt Department of Biomedical Engineering Vanderbilt Department of Medicine USA

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Anomalous properties of spark plasma sintered boron nitride solids

arXiv

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arXiv 2024年

作者： Biswas, Abhijit Serles, Peter Alvarez, Gustavo A. Schimpf, Jesse Hache, Michel Kong, Jonathan Demingos, Pedro Guerra Yuan, Bo Pieshkov, Tymofii S. Li, Chenxi Puthirath, Anand B. Gao, Bin Gray, Tia Zhang, Xiang Murukeshan, Jishnu Vajtai, Robert Dai, Pengcheng Singh, Chandra Veer Howe, Jane Zou, Yu Martin, Lane W. Clancy, James Patrick Tian, Zhiting Filleter, Tobin Ajayan, Pulickel M. Department of Materials Science and Nanoengineering Rice University HoustonTX77005 United States Department of Mechanical & Industrial Engineering University of Toronto 5 King’s College Road TorontoM5S 3G8 Canada Sibley School of Mechanical and Aerospace Engineering Cornell University IthacaNY14853 United States Department of Materials Science and Engineering University of California Berkeley United States Department of Materials Science and Engineering University of Toronto 184 College St TorontoM5S 3E4 Canada Department of Physics and Astronomy McMaster University HamiltonL8S 4M1 Canada Applied Physics Graduate Program Smalley-Curl Institute Rice University HoustonTX77005 United States Department of Physics and Astronomy Rice University HoustonTX77005 United States Materials Sciences Division Lawrence Berkeley National Laboratory United States

Hexagonal boron nitride (h-BN) is brittle, however, its atomic-scale structural engineering can lead to unprecedented physical properties. Here we report the bulk synthesis of high-density crystalline h-BN solids by using high-temperature spark plasma sintering (SPS) of micron size h-BN powders. In addition to the high mechanical strength and ductile response of such materials, we have obtained anomalous values of dielectric constant beyond theoretical limits, high thermal conductivity, and exceptional neutron radiation shielding capability. Through exhaustive characterizations we reveal that SPS induces non-basal plane crystallinity, twisting of layers, and facilitates inter-grain fusion with a high degree of in-plane alignment across macroscale dimensions, resulting in near-theoretical density and anomalous properties. Our findings highlight the importance of material design, via new approaches such as twisting and interconnections between atomically thin layers, to create novel ceramics with properties that could go beyond their intrinsic theoretical predictions. © 2024, CC BY.

关键词： Spark plasma sintering

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Technological advancements and opportunities in Neuromarketing: a systematic review

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Brain Informatics 2020年第1期7卷 1-19页

作者： Rawnaque, Ferdousi Sabera Rahman, Khandoker Mahmudur Anwar, Syed Ferhat Vaidyanathan, Ravi Chau, Tom Sarker, Farhana Mamun, Khondaker Abdullah Al Advanced Intelligent Multidisciplinary Systems Lab Institute of Advanced Research United International University Dhaka Bangladesh School of Business and Economics United International University Dhaka Bangladesh Institute of Business Administration University of Dhaka Dhaka Bangladesh Department of Mechanical Engineering Imperial College London London United Kingdom Institute of Biomaterials & Biomedical Engineering University of Toronto Toronto Canada Department of Computer Science and Engineering University of Liberal Arts Bangladesh Dhaka Bangladesh Department of Computer Science and Engineering United International University Dhaka Bangladesh

Neuromarketing has become an academic and commercial area of interest, as the advancements in neural recording techniques and interpreting algorithms have made it an effective tool for recognizing the unspoken response of consumers to the marketing stimuli. This article presents the very first systematic review of the technological advancements in Neuromarketing field over the last 5 years. For this purpose, authors have selected and reviewed a total of 57 relevant literatures from valid databases which directly contribute to the Neuromarketing field with basic or empirical research findings. This review finds consumer goods as the prevalent marketing stimuli used in both product and promotion forms in these selected literatures. A trend of analyzing frontal and prefrontal alpha band signals is observed among the consumer emotion recognition-based experiments, which corresponds to frontal alpha asymmetry theory. The use of electroencephalogram (EEG) is found favorable by many researchers over functional magnetic resonance imaging (fMRI) in video advertisement-based Neuromarketing experiments, apparently due to its low cost and high time resolution advantages. Physiological response measuring techniques such as eye tracking, skin conductance recording, heart rate monitoring, and facial mapping have also been found in these empirical studies exclusively or in parallel with brain recordings. Alongside traditional filtering methods, independent component analysis (ICA) was found most commonly in artifact removal from neural signal. In consumer response prediction and classification, Artificial Neural Network (ANN), Support Vector Machine (SVM) and Linear Discriminant Analysis (LDA) have performed with the highest average accuracy among other machine learning algorithms used in these literatures. The authors hope, this review will assist the future researchers with vital information in the field of Neuromarketing for making novel contributions. © 2020, The Author(s).

关键词： Independent component analysis

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Multimodal Spatial Attention Network for Automatic Head and Neck Tumor Segmentation in FDG-PET and CT Images 1

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2nd 3D Head and Neck Tumor Segmentation in PET/CT Challenge, HECKTOR 2021, held in conjunction with 24th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2021

作者： Cho, Minjeong Choi, Yujin Hwang, Donghwi Yie, Si Young Kim, Hanvit Lee, Jae Sung School of Electrical and Electronics Engineering Chung-Ang University Seoul06974 Korea Republic of Department of Biomedical Engineering Kyunghee University College of Electronics and Information 1732 Deogyeong-daero Giheung-gu Gyeonggi-do Yongin-si Korea Republic of Department of Nuclear Medicine Seoul National University College of Medicine Seoul03080 Korea Republic of Department of Biomedical Sciences Seoul National University College of Medicine Seoul03080 Korea Republic of Interdisciplinary Program in Bioengineering Seoul National University Graduate School Seoul Korea Republic of Integrated Major in Innovative Medical Science Seoul National University Graduate School Seoul Korea Republic of Ulsan Korea Republic of Artificial Intelligence Institute Seoul National University Seoul08826 Korea Republic of Brightonix Imaging Inc. Seoul04782 Korea Republic of

ISBN: (数字)9783030982539

ISBN: (纸本)9783030982522

Quantitative positron emission tomography/computed tomography (PET/CT), owing to the functional metabolic information and anatomical information of the human body that it presents, is useful to achieve accurate tumor delineation. However, manual annotation of a Volume Of Interest (VOI) is a labor-intensive and time-consuming task. In this study, we automatically segmented the Head and Neck (H&N) primary tumor in combined PET/CT images. Herein, we propose a convolutional neural network named Multimodal Spatial Attention Network (MSA-Net), supplemented with a Spatial Attention Module (SAM), which uses a PET image as an input. We evaluated this model on the MICCAI 2021 HEad and neCK TumOR (HECKTOR) segmentation challenge dataset. Our method delivered a competitive cross-validation efficiency, with Dice Similarity Coefficient (DSC) 0.757, precision 0.788, and recall 0.785. When we tested out method on test dataset, we achieved an average DSC and Hausdorff Distance at 95% (HD95) of 0.766 and 3.155 respectively. Our team name is ‘Heck_Uihak’. © 2022, Springer Nature Switzerland AG.

关键词： Tumors

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Experimental investigation of the effects of infusing a foam into hydrogels on the hyperelastic coefficients

Material Design and Processing Communications

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Material Design and Processing Communications 2021年第4期3卷

作者： Raheem, Hassan Mansour Al-Mukhtar, Ahmed M. Mechanical Department Faculty of Engineering University of Kufa Najaf Iraq Ministry of Oil Midland Refineries Company Karbala Refinery Karbala Iraq Biomedical Engineering Dept. College of Engineering University of Warith Alanbiyaa Baghdad Iraq Vff TUBA Freiberg Freiberg Germany

Hydrogels are viscoelastic material, soft and fragile materials that contain high water percent. These properties cannot sustain high axial compression loads. In this study, a foam was infused into hydrogel, agarose, to enhance the mechanical properties of the hydrogel/foam composite. Besides, it is difficult to measure the mechanical properties of the hydrogel alone specifically in tension because of the slipping in the grip during using the common tensile test. Therefore;the goal of this study is to investigate the influences of infused cellulose foam into the prepared hydrogels on the mechanical properties of the hydrogels by conducting the unconfined compression on hydrogel/foam composite and the hydrogel alone. It is also to utilize the strain energy density functions (SEDFs) to determine a suitable constitutive model that represents the nonlinear behavior of the materials. It is to predict the behavior of these materials out of range of the test (i.e., in tension) by implementing a finite elements analysis (FEA) using ABAQUS. The results showed that the strength of the hydrogel/foam composite was significantly greater than hydrogel alone. All hyperelastic models have well defined the nonlinear behavior of the experimental data. FEA results in tension are in good agreement with those predicted using hyperelastic models. © 2020 John Wiley & Sons, Ltd.

关键词： Hydrogels

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All-Aerosol-Sprayed High-Performance Transparent Triboelectric Nanogenerator with Embedded Charge-Storage Layer for Self-Powered Invisible Security Iot System and Raindrop-Solar Hybrid Energy Harvester

SSRN

引用

SSRN 2022年

作者： Kim, BaekGyu Song, Jin Yeong Kim, Do Young Lin, Zong-Hong Choi, Dongwhi Park, Sang Min School of Mechanical Engineering Pusan National University 2 Busandaehak-ro 63 Beon-Gil Geumjeong-gu Busan46241 Korea Republic of Institute of Biomedical Engineering Department of Power Mechanical Engineering Frontier Research Center on Fundamental and Applied Sciences of Matters National Tsing Hua University Hsinchu30013 Taiwan Kyung Hee University 1732 Deogyeong-daero Giheung-gu Gyeonggi-do Yongin-si17104 Korea Republic of

Practical utilization of the triboelectric nanogenerators (TENGs), which have unique advantageous aspects of a simple operation mechanism, material selection diversity, and high energy conversion efficiency, requires high functionality as well as its scalable fabrication to broaden the applicable fields. Here, we report the concept of all-aerosol-sprayed transparent TENG (ST-TENG) by sequentially spraying total three layers of silver nanowire conductive layer, transparent polystyrene charge-storage layer, and fluoropolymer contact layer. All layers were achieved by aerosol spray process, thereby exhibiting high design flexibility enough to fabricate ST-TENGs on various pre-made commercial devices. The presence of the transparent polystyrene layer as a charge storing interlayer significantly enhances the power density of the ST-TENG up to 818 mW/m2. As proof-of-concept applications, a self-powered invisible security internet-of-things system, which could blend with the surroundings, exploited biomechanical energy from foot-step for energy harvesting and invasion sensing. Furthermore, by exploiting the all-aerosol-spray process and high light transmittance of the ST-TENG, a hybrid energy harvester to simultaneously generate electricity from solar and raindrop energy was directly fabricated on a commercial solar panel. This work provides the brand-new concept of TENG with a scalable fabrication process, enhanced performance, and outstanding light transmittance. © 2022, The Authors. All rights reserved.

关键词： Nanogenerators

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Gas vesicle isolated from microorganisms to act as ultrasound contrast agent

引用

Research on biomedical engineering 2021年第1期37卷 1-7页

作者： Garrute, Felipe Vianna Machado, João Carlos Biomedical Engineering Program-COPPE Federal University of Rio de Janeiro Horácio Macedo Ave. 2030 Center of Technology Block H Room 327 Rio de JaneiroRJ21941-914 Brazil Post-graduate Program in Surgical Sciences Department of Surgery School of Medicine Federal University of Rio de Janeiro Carlos Chagas Filho Ave. 373 Health Sciences Center Block K Room 49 Rio de JaneiroRJ21941-902 Brazil

Purpose: Ultrasound contrast agent (UCA), used to enhance the contrast in ultrasonography, consists of microbubbles filled with an inert gas and encapsulated with a protein or a lipidic-stabilize membrane. The UCAs are able to resonate when exposed to ultrasound waves and to generate an echo-acoustic signal with increased intensity. Recently, a technique to produce UCA from microorganisms was developed and it consists of lysing microorganism cells to obtain gas vesicle (GV) after cultivation in the laboratory. GVs occur almost exclusively in aquatic microorganisms, as Microcystis aeruginosa (MYC), and provide buoyancy which permit to float towards the water surface. This work implemented a technique to produce GVs from MYC, at the Ultrasound Laboratory, and inspected their properties of acting as UCAs, analyzed through ultrasonic images acquired at 40 MHz, and their structural characteristics such as morphology, diameter, and length. Methods: After the cultivation of MYC, the buoyant cells with GVs were separated from the culture medium and submitted to cell lysis with chemical treatment. Thereafter, the solution with lysed cells was centrifuged, at 300g during 8 h at 4–8 °C, to isolate the GVs (absorbance 0.6, λ = 500 nm). Results: Transmission electron microscopy inspection revealed the MYC-GVs with elliptical morphology and having a diameter between 100 and 150 nm and length near to 200 nm. B-mode ultrasound images of the solutions proved the GV’s ability to generate an echo signal, thus confirming their performance as UCAs. © 2020, Sociedade Brasileira de Engenharia Biomedica.

关键词： Cytology

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Spectroscopic and Interferometric Sum-Frequency Imaging of Strongly Coupled Phonon Polaritons in SiC Metasurfaces

arXiv

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arXiv 2023年

作者： Niemann, Richarda Mueller, Niclas S. Wasserroth, Sören Lu, Guanyu Wolf, Martin Caldwell, Joshua D. Paarmann, Alexander Fritz-Haber-Institut der Max-Planck-Gesellschaft Faradayweg 4-6 Berlin14195 Germany Department of Mechanical Engineering Vanderbilt University NashvilleTN37235 United States Interdisciplinary Materials Science Graduate Program Vanderbilt University NashvilleTN37235 United States

Phonon polaritons enable waveguiding and localization of infrared light with extreme confinement and low losses. The spatial propagation and spectral resonances of such polaritons are usually probed with complementary techniques such as near-field optical microscopy and far-field reflection spectroscopy. Here, we introduce infrared-visible sum-frequency spectro-microscopy as a tool for spectroscopic imaging of phonon polaritons. The technique simultaneously provides sub-wavelength spatial resolution and highly-resolved spectral resonance information. This is implemented by resonantly exciting polaritons using a tunable infrared laser and wide-field microscopic detection of the upconverted light. We employ this technique to image hybridization and strong coupling of localized and propagating surface phonon polaritons in metasurfaces of SiC micropillars. Spectro-microscopy allows us to measure the polariton dispersion simultaneously in momentum space by angle-dependent resonance imaging, and in real space by polariton interferometry. Notably, we directly visualize how strong coupling affects the spatial localization of polaritons, inaccessible with conventional spectroscopic techniques. We further observe the formation of edge states at excitation frequencies where strong coupling prevents polariton propagation into the metasurface. Our approach is applicable to the wide range of polaritonic materials with broken inversion symmetry and can be used as a fast and non-perturbative tool to image polariton hybridization and propagation. © 2023, CC BY.

关键词： Polariton

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