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15th International Multi-Conference on Complexity, Informatics and Cybernetics, IMCIC 2024

作者： Ono, Ryuya Hashimoto, Shigehiro Biomedical Engineering Mechanical Engineering Kogakunin University Tokyo Japan Biomedical Engineering Department of Mechanical Engineering Kogakunin University Tokyo Japan

ISBN: (纸本)9781950492787

Cell sorting is a useful technique that can be applied to disease diagnosis and tissue formation technology. Dielectrophoresis has been attempted to be applied to cell sorting as a label-free, microinvasive sorting technique. This study aimed to create a device suitable for myoblast cell sorting based on previous research results. Using photolithography technology, microchannels with surface electrodes were designed and fabricated. © IMCIC 2024. All rights reserved.

关键词： Electrophoresis

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Development and Evaluation of Machine Learning Based Predictive Models for Tribological Properties of Blended Coatings at Elevated Temperature

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Journal of Bio- and Tribo-Corrosion 2025年第1期11卷 1-20页

作者： Jatavallabhula, Jagadesh Kumar Shabana, Shabana Pappula, Bridjesh Department of Mechanical Bioresources and Biomedical Engineering College of Science Engineering and Technology University of South Africa Florida Campus Johannesburg South Africa Department of Mechanical Engineering GST GITAM University Visakhapatnam India Johannesburg South Africa

The current research is undertaken to evaluate the Tribological properties like wear and Coefficient of Friction (CoF) of three popular blended coatings on a mild steel substrate at elevated temperature. The scope of the research also includes predicting the tribological properties by employing three Machine Learning (ML) based predictive models viz. Elastic Net, k-NN and Random Forest regressions. The regressions are fit and tested at different proportions of Training and Testing data to find the best proportion. Random Forest regression is observed to be the best fit based on the acceptable values of MSE and R-Squared. Random Forest regression model of wear yielded MSE and R-Squared values as 22.01 and 0.95 for Coating 1, 5.75 and 1 for Coating 2, and 14.13 and 1 for Coating 3, respectively. Likewise, Random Forest regression model of CoF yielded MSE and R-Squared values as 0.01 and 0.99 for Coating 1, 0 and 1 for Coating 2, and 0 and 1 for Coating 3, respectively. The deviation between the experimental and predicted results (tested data: experimental runs 3, 14, and 29) in wear using the Random Forest algorithm for Coating 1, Coating 2, and Coating 3 is found to be 21.18%, − 2.72%, and 0.42%;− 4.54%, − 13.87, and 2.57%;11.85%, 1.69%, and 1.89%, respectively. The deviation for CoF is found to be 6.29%, 1.56%, and 2.93%;− 0.86%, − 0.56%, and 0.20%;0.85%, − 0.19%, and 0.17%, respectively. The variance between the actual experimental and predicted results from Random Forest regression is observed to be relatively acceptable. © The Author(s) 2025.

关键词： Low carbon steel

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Novel PA encapsulated PCL hybrid coating for corrosion inhibition of biodegradable Mg alloys:A triple triggered self-healing response for synergistic multiple protection

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Journal of Magnesium and Alloys 2023年第4期11卷 1440-1460页

作者： Navdeep Singh Grewal Uma Batra Kamal Kumar Anil Mahapatro Department of Metallurgical and Materials Engineering Punjab Engineering CollegeChandigarh 160012India Department of Mechanical Engineering Punjab Engineering CollegeChandigarh 160012India Department of Biomedical Engineering Wichita State UniversityWichitaKS 67260USA

Surface coatings have been extensively used to control the degradation rate of Mg alloys for bioimplant ***,these coatings only act as passive *** corrosive media,structural damage impairs their barrier properties,resulting in rapid degradation of Mg *** present study incorporates phytic acid(PA)as a healing agent in polycaprolactone(PCL)microcapsules with a unique honeycomb core matrix to obtain a self-healing PA-PCLcaps *** contact between simulated body fluid(SBF)and PA-PCLcaps coated ZM21 exhibited Cassie-Baxter interfacial states,resulting in significant hydrophobicity with a contact angle(CA)of *** corrosion potential(Ecorr)and current density(Icorr)were found to be-0.28 V and 1.1×10^(-9)A/cm^(2),respectively,for PA-PCLcaps coating,resulting in biosafe corrosion rate of 2.5×10^(-4)mm/*** mechanical scratching,rapid HA mineralization at scratched regions recovered the hydrogen evolution rate(HER,0.36 mL/cm^(2)/day)and pH change(pH 7.10)of scratched PA-PCLcaps coated ZM21 samples to corresponding unscratched samples within one day of *** coating’s self-healing ability could be attributed to PA released from punctured microcapsules,which facilitates HA *** pH-triggered(pH 10)and Mg(II)-triggered(5 mM)conditions enhanced PA release from PA-PCLcaps coating by 2.5 and 3.1 times,*** a result,dense HA mineralization occurred,which protects the coating from structural defects and ensures its durability in stimulating *** findings of present study provide new insight for design of multiple stimuli-feedback based self-healing coatings on biodegradable Mg alloys.

关键词： Self-healing coating Corrosion resistance Magnesium alloy Phytic acid Polycaprolactone microcapsules

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A possible solution for noise attenuation material for urban buses: The downtown São Paulo case study

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Noise and Vibration Worldwide 2025年第3期56卷 137-147页

作者： Monteiro, Elvis C Avila, Antonio F Division Stellantis Betim Brazil Mechanical Engineering Graduate Studies Program Universidade Federal de Minas Gerais Belo Horizonte Brazil Department of Mechanical Engineering and Mechanical Engineering Graduate Studies Program Universidade Federal de Minas Gerais Belo Horizonte Brazil

Urban buses, particularly in large cities, are exposed to significant noise pollution. This paper presents a new family of materials at the micro/nano level designed for urban noise attenuation, specifically for application in urban buses. Melamine foam is combined in series with nanomembranes, creating a composite material that functions as a Helmholtz resonator. As sound waves pass over the nanomembranes, they are disturbed, and the sound resonates within the melamine foam. This interaction reduces the energy of the sound waves and enhances the noise absorption coefficient. In ten cases studied, the average sound absorption coefficient was approximately 89%, with peak frequencies ranging from 2400 Hz to 4300 Hz. The average thickness of the nanomembranes was around 5.0 µm, while the melamine foam had a thickness of 13 mm. The mean noise reduction achieved was about 11 dB, which depends on factors such as the morphology, thickness, and pore size of the nanomembranes. A case study conducted in downtown São Paulo demonstrated that applying these materials to urban buses can significantly reduce interior noise levels. Finally, the proposed system is fully scalable and adaptable for various applications where acoustic insulation is required. © The Author(s) 2025.

关键词： Noise pollution

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Recent development in multizonal scaffolds for osteochondral regeneration

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Bioactive Materials 2023年第7期25卷 122-159页

作者： Le Yu Sacha Cavelier Brett Hannon Mei Wei Department of Chemical and Biomolecular Engineering Ohio UniversityAthensOH45701USA Biomedical Engineering Program Ohio UniversityAthensOH45701USA Department of Mechanical Engineering Ohio UniversityAthensOH45701USA

Osteochondral(OC)repair is an extremely challenging topic due to the complex biphasic structure and poor intrinsic regenerative capability of natural osteochondral *** contrast to the current surgical approaches which yield only short-term relief of symptoms,tissue engineering strategy has been shown more promising outcomes in treating OC defects since its emergence in the *** particular,the use of multizonal scaffolds(MZSs)that mimic the gradient transitions,from cartilage surface to the subchondral bone with either continuous or discontinuous compositions,structures,and properties of natural OC tissue,has been gaining momentum in recent *** the latest developments in the field,this review offers a comprehensive summary of recent advances,current hurdles,and future perspectives of OC repair,particularly the use of MZSs including bilayered,trilayered,multilayered,and gradient scaffolds,by bringing together onerous demands of architecture designs,material selections,manufacturing techniques as well as the choices of growth factors and cells,each of which possesses its unique challenges and opportunities.

关键词： Multizonal scaffolds Osteochondral regeneration Fabrication Cells Growth factors

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Physics guided heat source for quantitative prediction of IN718 laser additive manufacturing processes

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npj Computational Materials 2024年第1期10卷 2854-2867页

作者： Abdullah Al Amin Yangfan Li Ye Lu Xiaoyu Xie Zhengtao Gan Satyajit Mojumder Gregory J.Wagner Wing Kam Liu Department of Mechanical Engineering Northwestern UniversityEvanston 60208 ILUSA Department of Mechanical and Aerospace Engineering University of DaytonDaytonOHUSA Department of Mechanical Engineering University of MarylandBaltimore CountyBaltimoreMD 21250USA Department of Aerospace&Mechanical Engineering University of Texas at El PasoEl PasoTXUSA Theoritical and Applied Mechanics Program Northwestern UniversityEvanston 60208 ILUSA

Challenge 3 of the 2022 NIST additive manufacturing benchmark(AM Bench)experiments asked modelers to submit predictions for solid cooling rate,liquid cooling rate,time above melt,and melt pool geometry for single and multiple track laser powder bed fusion process using moving *** in-house developed Additive Manufacturing Computational Fluid Dynamics code(AM-CFD)combined with a cylindrical heat source is implemented to accurately predict these *** heat source calibration is proposed relating volumetric energy density(ψ)based on experiments available in the *** parameters of the heat source of the computational model are initially calibrated based on a Higher Order Proper Generalized Decomposition-(HOPGD)based surrogate *** prediction using the calibrated heat source agrees quantitatively with NIST measurements for different process conditions(laser spot diameter,laser power,and scan speed).A scaling law based on keyhole formation is also utilized in calibrating the parameters of the cylindrical heat source and predicting the challenge *** addition,an improvement on the heat source model is proposed to relate the Volumetric Energy Density(VED_(σ))to the melt pool aspect *** model shows further improvement in the prediction of the experimental measurements for the melt pool,including cases at higher VED_(σ).Overall,it is concluded that the appropriate selection of laser heat source parameterization scheme along with the heat source model is crucial in the accurate prediction of melt pool geometry and thermal measurements while bypassing the expensive computational simulations that consider increased physics equations.

关键词： prediction source additive

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Sound innovations for biofabrication and tissue engineering

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Microsystems & Nanoengineering 2024年第6期10卷 1-19页

作者： Mengxi Wu Zhiteng Ma Zhenhua Tian Joseph T.Rich Xin He Jianping Xia Ye He Kaichun Yang Shujie Yang Kam W.Leong Luke P.Lee Tony Jun Huang School of Mechanical Engineering Dalian University of TechnologyDalian 116086 LiaoningChina Thomas Lord Department of Mechanical Engineering and Materials Science Duke UniversityDurhamNC 27708USA Department of Mechanical Engineering Virginia Polytechnic Institute and State UniversityBlacksburgVA 24060USA Department of Biomedical Engineering Duke UniversityDurhamNC 27708USA Renal Division and Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02115USA Department of Biomedical Engineering Columbia UniversityNew YorkNY 10027USA

Advanced biofabrication techniques can create tissue-like constructs that can be applied for reconstructive surgery or as in vitro three-dimensional(3D)models for disease modeling and drug *** various biofabrication techniques have recently been widely reviewed in the literature,acoustics-based technologies still need to be *** rapidly increasing number of publications in the past two decades exploring the application of acoustic technologies highlights the tremendous potential of these *** this review,we contend that acoustics-based methods can address many limitations inherent in other biofabrication techniques due to their unique advantages:noncontact manipulation,biocompatibility,deep tissue penetrability,versatility,precision in-scaffold control,high-throughput capabilities,and the ability to assemble multilayered *** discuss the mechanisms by which acoustics directly dictate cell assembly across various biostructures and examine how the advent of novel acoustic technologies,along with their integration with traditional methods,offers innovative solutions for enhancing the functionality of *** technologies are poised to address fundamental challenges in biofabrication and tissue engineering and show promise for advancing the field in the coming years.

关键词： acoustics limitations innovative

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Convex Approach to Real-Time Multiphase Trajectory Optimization for Urban Air Mobility

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Journal of Air Transportation 2025年第1期33卷 69-85页

作者： Wu, Yufei Deniz, Sabrullah Shi, Yang Wang, Zhenbo Department of Mechanical Aerospace and Biomedical Engineering University of Tennessee AIAA KnoxvilleTN37996 United States

Electric vertical takeoff and landing technology has emerged as a promising solution to alleviate ground transportation congestion. However, the limited capacity of onboard batteries enforces hard time constraints for vehicle operations in a complex urban environment. Therefore, a constrained, real-time trajectory optimization method is necessary to enable safe and energy-efficient vehicle flight. Unfortunately, most existing trajectory optimization methods suffer from low computational efficiency, unpredictable convergence processes, and strong dependence on a good initial trajectory. In this paper, we employ a successive convex programming approach to solve the multiphase minimum-energy-cost electric vertical takeoff and landing vehicle trajectory optimization problem for urban air mobility applications. The main contribution is the development and validation of two novel convexification methods that find approximate optimal solutions to the multiphase nonlinear trajectory optimization problem in real time by solving a sequence of convex subproblems. Specifically, the first method transforms the original nonlinear problem into a sequence of second-order cone programming problems through a convenient change of variables and lossless convexification, while the second approach achieves a similar goal without the need for control convexification. The resulting convex subproblems can be solved reliably in real time by advanced interior point methods. The proposed methods are demonstrated through numerical simulations of two different urban air mobility scenarios and compared with the solution obtained from GPOPS-II, a state-of-the-art general-purpose optimal control solver. Our proposed sequential convex programming methods can obtain near-optimal solutions with faster computational speed than GPOPS-II. © 2024 by the American Institute of Aeronautics and Astronautics, Inc. All rights reserved.

关键词： Constrained optimization

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Dual-compressed photoacoustic single-pixel imaging

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National Science Review 2023年第1期10卷 187-195页

作者： Yuning Guo Baowen Li Xiaobo Yin Department of Mechanical Engineering University of Colorado Department of Material Science and Engineering Department of Physics Shenzhen Institute for Quantum Science and Engineering Southern University of Science and Technology Materials Science and Engineering Program University of Colorado

Photoacoustic imaging,an acoustic imaging modality with potentially optical resolution in an optical turbid medium,has attracted great ***,the convergence of wavefront optimization and raster scanning in computational photoacoustic imaging leads to the challenge of fast mapping,especially for a spatial resolution approaching the acoustic deep-subwavelength *** a sparse sampling paradigm,compressive sensing has been applied in numerous fields to accelerate data acquisition without significant quality *** this work,we propose a dual-compressed approach for photoacoustic surface tomography that enables high-efficiency imaging with 3D spatial resolution unlimited by the acoustics in a turbid *** dual-compressed photoacoustic imaging with single-pixel detection,enabled by spatially optical modulation with synchronized temporally photoacoustic coding,allows decoding of the fine optical information from the modulated acoustic signal even when the variance of original photoacoustic signals is *** perform a proof-of-principle numerical demonstration of dual-compressed photoacoustic imaging, that resolves acoustic sub-acoustic-wavelength details with a significantly reduced number of measurements,revealing the potential for dynamic *** dual-compressed concept,which transforms unobtrusive spatial difference into spatio-temporal detectable information,can be generalized to other imaging modalities to re alize efficient,high-spatial-resolution imaging.

关键词： photoacoustic imaging compressive sensing single-pixel imaging surface tomography

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The development of video laryngoscope via additive manufacturing for use in a pre-hospital environment

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Research on biomedical engineering 2024年第1期40卷 15-23页

作者： Alves, Marcio Allan Foggiatto, Jose Aguiomar Berti, Lucas Freitas Ulbricht, Leandra Graduate Program in Biomedical Engineering Universidade Federal Tecnológica do Paraná Curitiba Brazil Graduate Program in Mechanical and Materials Engineering Universidade Federal Tecnológica do Paraná Curitiba Brazil

Purpose: Due to failures that occur during intubation, some authors advocate that intubation should always be done with a video laryngoscope. What makes the implementation of this recommendation difficult, especially in developing countries, is the high price of the device. Thus, the objective of this study is to present a low-cost video laryngoscope developed via additive manufacturing, being the first device to have the safety parameters duly tested according to the ISO 7673:2020 standard. Methods: A video laryngoscope with a Macintosh-type rigid blade was developed. After modeling it in the CAD-3D SolidWorks® program, the prototype was printed in PLA (polylactic acid), and load and fatigue tests were carried out with the MTS 810/793 testing machine. Results: The main results were an improvement in ergonomics (with a better fixation of the camera wire and camera positioning). Load and fatigue tests showed compliance with the requirements of the ISO 7673:2020 standard. The first is that when subjected to a traction force of 65 N, the center of illumination must not move more than 10 mm (the average movement was only 3.95 mm). The second is that when subjected to a traction force of 150 N, the laryngoscope blade must not break (348 N of load was applied and the piece resisted without breaking). Conclusion: It was shown that the Macintosh-type PLA video laryngoscope has the potential to become a safe and low-cost tool in the emergency intubation arsenal. © The Author(s), under exclusive licence to The Brazilian Society of biomedical engineering 2023.

关键词： 3D printing

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