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2023 IEEE International Conference on Smart Information Systems and Technologies, SIST 2023

作者： Abdildin, Yerkin Narbayev, Dinmukhammedali Viderman, Dmitriy School of Engineering and Digital Sciences Nazarbayev University Department of Mechanical and Aerospace Engineering Astana Kazakhstan School of Medicine Nazarbayev University Department of Biomedical Sciences Astana Kazakhstan

ISBN: (纸本)9798350335040

Morphine reduces postoperative pain but may cause adverse events. Statistical analysis is often used to evaluate treatments. In this paper, we compare the effect of extended-release epidural morphine 10 mg dose (EREM 10 mg) and morphine sulfate 4-5 mg dose (MS 4-5 mg) on postoperative medical outcomes. We conduct statistical analysis of research articles published in English before November of 2022. The analysis was done by extracting statistical data, calculating mean differences (MD) between EREM 10 mg and MS 4-5 mg groups for continuous data and risk ratios (RR) for dichotomous data, and analyzing these statistics for important medical outcomes. The results of our analysis favor the EREM 10 mg group over the MS 4-5 mg group in postoperative opioid consumption in morphine equivalents (mg);MD with 95% CI is -13.25 [-26.40, -0.09], p-value= 0.05. However, in postoperative adverse events (no.), the overall effect of the model favors the MS 4-5 mg group over the EREM 10 mg group;RR with 95% CI is 1.29 [1.10, 1.51], p-value=0.002. In a subgroup analysis, the model favors the MS 4-5 mg group over the EREM 10 mg group only in pruritus. These results are statistically significant. There were no significant differences between the groups in the incidence of nausea, vomiting, urinary retention, somnolence, and hypoxia. Our analysis shows interesting results: although patients in the EREM 10 mg group consumed 13.25 mg less morphine (on average), they had a higher risk ratio for adverse events compared to patients in the MS 4-5 mg group. This indicates that more randomized controlled trials should be conducted in the future to determine the advantages of each method. © 2023 IEEE.

关键词： Sulfur compounds

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Automatic Control System for Reach-to-Grasp Movement of a 7-DOF Robotic Arm Using Object Pose Estimation with an RGB Camera

Automatic Control System for Reach-to-Grasp Movement of a 7-...

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2023 IEEE International Conference on Robotics and Biomimetics, ROBIO 2023

作者： Bai, Shuting Guo, Jiazhen Jiang, Yinlai Yokoi, Hiroshi Togo, Shunta Electro-Communications University Department of Mechanical and Intelligent Systems Engineering Tokyo Japan Electro-Communications University Center for Neuroscience and Biomedical Engineering Tokyo Japan

ISBN: (纸本)9798350325706

In this study, we develop an automatic control system to perform the reach-to-grasp movement of a 7-DOF (Degrees of Freedom) robotic arm that has the same DOFs as a human arm, and an end-effector with the same shape as a human hand. The 6-DOF pose of the object to be grasped is estimated in real time only from RGB images using a neural network based object pose estimation model. Based on this information, motion planning is performed to automatically control the reach-to-grasp movement of the robotic arm. In the evaluation experiment, the 7-DOF robotic arm performs reach-to-grasp movements for a household object in different poses using the developed control system. The results show that the control system developed in this study can automatically control the reach-to-grasp movement to an object in a certain arbitrary pose. © 2023 IEEE.

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Investigation of thermal conductivity and physical properties of oil palm trunks/ramie fiber reinforced biopolymer hybrid composites as building bio-insulation

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Materials Today: Proceedings 2022年 60卷 373-377页

作者： Mawardi, Indra Aprilia, Sri Faisal, Muhammad Rizal, Samsul Doctoral Program School of Engineering Post Graduate Program Universitas Syiah Kuala Banda Aceh23111 Indonesia Department of Mechanical Engineering Politeknik Negeri Lhokseumawe Lhokseumawe24301 Indonesia Department of Chemical Engineering Universitas Syiah Kuala Banda Aceh23111 Indonesia Department of Mechanical Engineering Universitas Syiah Kuala Banda Aceh23111 Indonesia

The current buildings insulating materials in the construction market, which mainly consist of synthetic materials, have a high performance in thermal resistivity. However, they negatively impact the human health and the environment, thereby finding bio-insulating materials is necessary. This research investigates the thermal conductivity and physical performance of oil palm trunks/ramie fibers reinforced biopolymer hybrid composites for thermal insulation of buildings. The hybrid composites were further prepared using oil palm trunk particles, ramie fiber as the reinforcement, and tapioca starch as a biopolymer binder. All the manufactured hybrid composites exhibited thermal conductivity in a range of 0.0723 W/mK to 0.1344 W/mK and density of 732 kg/m3 to 801 kg/m3, respectively. Sample C1, with a density of 732 kg/m3 had the lowest thermal conductivity of (0.0723 W/mK). Moreover, the minimum absorbed water (53.66%) and thickness swelling (21.36%) were found in the C1 sample hybrid composites after 24-hours immersion in water. Thermal conductivity performance was influenced positively by physical properties. Therefore, the results of this research show that waste oil palm trunks and ramie fiber could be used as a thermal insulating material for buildings. © 2022

关键词： Thermal conductivity

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NIR-Responsive Methotrexate-Modified Iron Selenide Nanorods for Synergistic Magnetic Hyperthermic, Photothermal, and Chemodynamic Therapy

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ACS Applied Materials and Interfaces 2024年第20期16卷 25622-25636页

作者： Thirumurugan, Senthilkumar Muthiah, Kayalvizhi Samuvel Lin, Yu-Chien Dhawan, Udesh Liu, Wai-Ching Wang, An-Ni Liu, Xinke Hsiao, Michael Tseng, Ching-Li Chung, Ren-Jei No. 1 Section 3 Zhongxiao East Road Taipei10608 Taiwan Centre for the Cellular Microenvironment Division of Biomedical Engineering James Watt School of Engineering Mazumdar-Shaw Advanced Research Centre University of Glasgow GlasgowG116EW United Kingdom Faculty of Science and Technology Technological and Higher Education Institute of Hong Kong Hong Kong New Territories999077 Hong Kong Scrona AG Grubenstrasse 9 Zürich8045 Switzerland College of Materials Science and Engineering Chinese Engineering and Research Institute of Microelectronics Shenzhen University Shenzhen518060 China Department of Electrical and Computer Engineering National University of Singapore Singapore117583 Singapore Genomics Research Center Academia Sinica Taipei115 Taiwan Department and Graduate Institute of Veterinary Medicine School of Veterinary Medicine National Taiwan University Taipei10617 Taiwan Graduate Institute of Biomedical Materials and Tissue Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan International Ph.D. Program in Biomedical Engineering College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan Research Center of Biomedical Device College of Biomedical Engineering Taipei Medical University Taipei11031 Taiwan International Ph.D. Program in Cell Therapy and Regenerative Medicine College of Medicine Taipei Medical University Taipei11031 Taiwan Taipei10608 Taiwan

Breast cancer is a malignant tumor with a high mortality rate among women. Therefore, it is necessary to develop novel therapies to effectively treat this disease. In this study, iron selenide nanorods (FeSe2 NRs) were designed for use in magnetic hyperthermic, photothermal, and chemodynamic therapy (MHT/PTT/CDT) for breast cancer. To illustrate their efficacy, FeSe2 NRs were modified with the chemotherapeutic agent methotrexate (MTX). MTX-modified FeSe2 (FeSe2-MTX) exhibited excellent controlled drug release properties. Fe2+ released from FeSe2 NRs induced the release of •OH from H2O2 via a Fenton/Fenton-like reaction, enhancing the efficacy of CDT. Under alternating magnetic field (AMF) stimulation and 808 nm laser irradiation, FeSe2-MTX exerted potent hyperthermic and photothermal effects by suppressing tumor growth in a breast cancer nude mouse model. In addition, FeSe2 NRs can be used for magnetic resonance imaging in vivo by incorporating their superparamagnetic characteristics into a single nanomaterial. Overall, we presented a novel technique for the precise delivery of functional nanosystems to tumors that can enhance the efficacy of breast cancer treatment. © 2024 The Authors. Published by American Chemical Society

关键词： Magnetic resonance imaging

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Unveiling bulk and surface radiation forces in a dielectric liquid

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Light(Science & Applications) 2022年第5期11卷 925-934页

作者： N.G.C.Astrath G.A.S.Flizikowski B.Anghinoni L.C.Malacarne M.L.Baesso T.Požar M.Partanen I.Brevik D.Razansky S.E.Bialkowski Department of Physics Universidade Estadual de MaringáMaringáPRBrazil Faculty of Mechanical Engineering University of LjubljanaLjubljanaSlovenia Department of Electronics and Nanoengineering Aalto UniversityAaltoFinland Department of Energy and Process Engineering Norwegian University of Science and TechnologyTrondheimNorway Institute for Biomedical Engineering and Institute of Pharmacology and Toxicology Faculty of MedicineUniversity of ZurichZurichSwitzerland Institute for Biomedical Engineering Department of Information Technology and Electrical EngineeringETH ZurichZurichSwitzerland Department of Chemistry and Biochemistry Utah State UniversityLoganUTUSA

Precise control over light-matter interactions is critical for many optical manipulation and material characterization methodologies,further playing a paramount role in a host of nanotechnology ***,the fundamental aspects of interactions between electromagnetic fields and matter have yet to be established unequivocally in terms of an electromagnetic momentum ***,we use tightly focused pulsed laser beams to detect bulk and boundary optical forces in a dielectric *** the optical convoluted signal,we decouple thermal and nonlinear optical effects from the radiation forces using a theoretical interpretation based on the Microscopic Ampère force *** is shown,for the first time,that the time-dependent pressure distribution within the fluid chiefly originates from the electrostriction *** results shed light on the contribution of optical forces to the surface displacements observed at the dielectric air-water interfaces,thus shedding light on the long-standing controversy surrounding the basic definition of electromagnetic momentum density in matter.

关键词： dielectric momentum surface

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Model of atomized droplets average particle size and verification of eco-friendly hybrid lubrication(CAMQL)

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摩擦（英文版） 2025年第5期13卷 149-164页

作者： Mingzheng Liu Changhe Li Dongzhou Jia Xin Liu Yanbin Zhang Min Yang Xin Cui Teng Gao Yusuf Suleiman Dambatta Runze Li Key Lab of Industrial Fluid Energy Conservation and Pollution Control Ministry of EducationQingdao University of TechnologyQingdao 266520China Key Lab of Industrial Fluid Energy Conservation and Pollution Control Ministry of EducationQingdao University of TechnologyQingdao 266520China Qingdao Jimo Qingli Intelligent Manufacturing Industry Research Institute Qingdao 266201China College of Mechanical Engineering and Automation Liaoning University of TechnologyJinzhou 121001China School of Mechanical Engineering Dalian University of TechnologyDalian 116081China School of Engineering Department of Biomedical EngineeringMassachusetts Institute of TechnologyBoston 02139USA

In the precision cutting of difficult-to-process metals,surface thermal damage to a workpiece is a significant technical *** clean minimum quantity lubrication(MQL)technology,which replaces traditional pouring cooling,is used,inadequate heat dissipation remains an *** air MQL(CAMQL),an eco-friendly technology,can enhance the heat transfer performance of the lubricating film in the cutting zone,offering excellent cooling and lubrication ***,the influence of jet and temperature parameters on the average particle size and distribution characteristics of atomized droplets is not well *** study first analyzes the evolution of lubricant physical properties and establishes a quantitative mapping relationship between cryogenic air temperature and physical parameters of ***,the unstable fluctuation in the annular liquid film at the two-phase flow nozzle exit is observed and analyzed.A thickness model of annular liquid film is developed,revealing the effect of airflow field on the annular liquid ***,a model for the average particle size of atomized droplets under CAMQL is *** analysis and validation experiments under different working conditions show that the measured values align with the theoretical *** an air pressure of 0.4 MPa and an air flow temperature of-50 °C,the droplet particle size is 133.5 μm,with an error of 8.2%.The effect of air pressure on particle size is greater than that of air flow ***,the distribution spans of droplet size under different conditions are analyzed,and the results demonstrated that low temperatures help shorten the interval between particle sizes and improve the relative uniformity of particle size *** research provides a theoretical basis for the application of CAMQL technology in the cutting process.

关键词： cryogenic air minimum quantity lubrication(MQL) atomization average particle size mathematical model

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A study on the feasibility of friction stir welding in joining dissimilar metals for SS400 and Ti-6Al-4V 9

A study on the feasibility of friction stir welding in joini...

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9th International Conference on Precision Machinery and Manufacturing Technology, ICPMMT 2024

作者： Hsieh, M.J. Chu, L.M. Chang, Y.P. Department of Power Mechanical Engineering National Taitung Junior College Taitung950303 Taiwan Interdisciplinary Program of Green and Information Technology National Taitung University Taitung95092 Taiwan Department of Mechanical Engineering Kun Shan University Tainan71000 Taiwan

This study designed friction stir multi-pass welding machine to conduct friction stir welding on carbon steel/titanium alloy clad sheets. The experimental process utilized the pin and pinless tools. The results demonstrate that the two dissimilar materials can be welded using the assembly-embedded rod pinless tool under the following welding conditions: a rotational speed of 1200 rpm, a downward force of 4 kN, a welding speed of 15 mm/min, and tool offset distances of 5 and 10 mm. Furthermore, this study investigated the microstructure and mechanical properties of the weld. In addition, the peak temperature measured at the joint interface exceeded the β phase transition temperature of the titanium alloy and surpassed 1000oC. The shear tensile test shows the weld's failure load was about 4300 N. The intermetallic compound at the welding interface has a microhardness value of approximately 400 Hv. According to the results of SEM observations and EDS composition element analysis, the elements of low carbon steel and titanium alloy at the interface of the clad sheet diffused and formed Fe-Ti intermetallic compounds. © 2024 Institute of Physics Publishing. All rights reserved.

关键词： Titanium alloys

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Lipid nanoparticles deliver mRNA to the blood-brain barrier

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Nano Research 2024年第10期17卷 9126-9134页

作者： Yanina Kuzminich Avraham Shakked Randi Calkins Sebastian Rudden Camille Jones Jessie Doan Bora Jang Elisa Schrader Echeverri Ryan Zenhausern Liming Lian David Loughrey Hannah E.Peck Rachelle Wiese Dorothy Koveal Philip J.Santangelo James E.Dahlman George C.Woodruff School of Mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Parker H.Petit Institute for Bioengineering and Biosciences Georgia Institute of TechnologyAtlantaGA 30332USA Wallace H.Coulter Department of Biomedical Engineering Emory University School of Medicine and Georgia Institute of TechnologyAtlantaGA 30332USA

Lipid nanoparticles(LNPs)have delivered RNA to hepatocytes in patients after intravenous *** clinical data support efforts to design LNPs that transfect cells in the central nervous system(CNS).However,delivery to the CNS has been difficult,in large part because quantifying on-target delivery alongside common off-target cell types in adult mice remains *** we report methods to isolate different cell types from the CNS,and subsequently present mRNA delivery readouts using a liver-detargeted *** data suggest that LNPs without targeting ligands can transfect cerebral endothelial cells in mice after intravenous *** the difficulty of crossing the blood-brain barrier,they also underscore the value of quantifying delivery in the CNS with cell-type resolution instead of whole-tissue resolution.

关键词： lipid nanoparticle mRNA nanomedicine central nervous system blood-brain barrier

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Automatic Anti-Swing Gantry Crane Based on Gradient Descent Optimization Proportional Integrated Derivative (PID): A Comparison Simulation and Real Experiment

Automatic Anti-Swing Gantry Crane Based on Gradient Descent ...

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2023 International Conference on Electrical engineering and Informatics, ICEEI 2023

作者： Qadri, Munzir Harjanto, Danang Karuna Miharja, Jonathan Astuti, Winda Mariana, Yosica Tan, Sofyan Solihin, Mahmud Iwan University of Muhammadiyah Jakarta Engineering Faculty Mechanical Engineering Department Jakarta10510 Indonesia Binus Aso School of Engineering Bina Nusantara University Automotive and Robotics Program Computer Engineering Department Jakarta11480 Indonesia Binus Aso School of Engineering Bina Nusantara University Product Design Program Industrial Engineering Department Jakarta11480 Indonesia Ucsi University Departement of Mechanical & Mechatronics Engineering Kuala Lumpur Malaysia

ISBN: (纸本)9798350381290

Transporting payload with precise swing angles and transfer times poses a challenging task in building construction, which is why gantry crane systems are extensively utilized. Various control strategies, including open-loop and closed-loop systems, have been proposed to tackle this issue. However, most of these controllers rely on a model and parameters specific to the crane system, making the process of modeling and parameter identification complex and time-consuming. To address this challenge, this work presents a practical and simulation control method for automatic gantry cranes, which is evaluated simulation and experimentally. The lab-scale Gantry crane is developed in this work, which consists of mechanical and electrical parts. Proportional Integral and Derivative (PID) and Proportional Derivative (PD) controllers which applied optimization method are implemented in the electrical part of the system. The PID and PD controller applied in controlled the position and swing angle, respectively. The Gradient Decent optimization method is the best optimization method in determining the parameter of the controller, since it has the best simulation performance in the output of the system. The experimental result is developed and compared between simulation and lab-scale Gantry crane hardware implementation part. The performance of experimental results is shown appropriately approaching the performance of the simulation result, with the approximately settling time. © 2023 IEEE.

关键词： Proportional control systems

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Numerical and experimental evaluation of low-intensity transcranial focused ultrasound wave propagation using human skulls for brain neuromodulation

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Medical Physics 2023年第1期50卷 38-49页

作者： Chen, Mengyue Peng, Chang Wu, Huaiyu Huang, Chih-Chung Kim, Taewon Traylor, Zachary Muller, Marie Chhatbar, Pratik Y. Nam, Chang S. Feng, Wuwei Jiang, Xiaoning Department of Mechanical and Aerospace Engineering North Carolina State University RaleighNC United States Department of Neurology Duke University School of Medicine DurhamNC United States Edward P. Fitts Department of Industrial and Systems Engineering North Carolina State University RaleighNC United States School of Biomedical Engineering ShanghaiTech University Shanghai China Department of Biomedical Engineering National Cheng Kung University Tainan Taiwan

Background: Low-intensity transcranial focused ultrasound (tFUS) has gained considerable attention as a promising noninvasive neuromodulatory technique for human brains. However, the complex morphology of the skull hinders scholars from precisely predicting the acoustic energy transmitted and the region of the brain impacted during the sonication. This is due to the fact that different ultrasound frequencies and skull morphology variations greatly affect wave propagation through the skull. Purpose: Although the acoustic properties of human skull have been studied for tFUS applications, such as tumor ablation using a multielement phased array, there is no consensus about how to choose a single-element focused ultrasound (FUS) transducer with a suitable frequency for neuromodulation. There are interests in exploring the magnitude and dimension of tFUS beam through human parietal bone for modulating specific brain lobes. Herein, we aim to investigate the wave propagation of tFUS on human skulls to understand and address the concerns above. Methods: Both experimental measurements and numerical modeling were conducted to investigate the transmission efficiency and beam pattern of tFUS on five human skulls (C3 and C4 regions) using single-element FUS transducers with six different frequencies (150–1500 kHz). The degassed skull was placed in a water tank, and a calibrated hydrophone was utilized to measure acoustic pressure past it. The cranial computed tomography scan data of each skull were obtained to derive a high-resolution acoustic model (grid point spacing: 0.25 mm) in simulations. Meanwhile, we modified the power-law exponent of acoustic attenuation coefficient to validate numerical modeling and enabled it to be served as a prediction tool, based on the experimental measurements. Results: The transmission efficiency and −6 dB beamwidth were evaluated and compared for various frequencies. An exponential decrease in transmission efficiency and a logarithmic decrease

关键词： Ultrasonic applications

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