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23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

作者： Salari, Alinaghi Appak-Baskoy, Sila Kolios, Michael C. Tsai, Scott S.H. Canada Biomedical Engineering Graduate Program Ryerson University Canada Department of Chemistry and Biology Ryerson University Canada Department of Physics Ryerson University Canada Department of Mechanical and Industrial Engineering Ryerson University Canada

ISBN: (纸本)9781733419000

The interaction of an acoustic field and an elastic material (e.g., microbubble) can give rise to the formation of a steady-state flow called acoustic streaming. In biomechanics, cells can be modelled as viscoelastic materials, and therefore, are able to sustain mechanical perturbations. Here, we demonstrate that adherent cells can induce acoustic microstreaming once excited by surface acoustic waves in a polydimethylsiloxane (PDMS) microfluidic device. This streaming flow is captured by confocal microscopy at different heights of the cell and compared to numerical results for two cells with different shapes. © 2019 CBMS-0001.

关键词： Cells

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Concept selection and Kinematic modeling of hand rehabilitation robotic device

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IOP Conference Series: Materials Science and engineering 2021年第1期1132卷

作者： Sunil Meby Mathew A.P. Sudheer Mechatronics/Robotics Laboratory Department of Mechanical Engineering National Institute of Technology Calicut Kerala India

Rehabilitation using an exoskeleton is one of the widely accepted methods for the recovery of lost motor abilities. Most of the present research concentrates on either soft or rigid exoskeletons. In this paper, the design of a five-finger exoskeleton is discussed along with the advantage of soft and rigid bodied exoskeletons. Concept selection for the designs is done using the standard procedure of screening and scoring. Forward and inverse kinematic modeling of thumb and index finger is performed with Denavit-Hartenberg (DH) method.

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Evaluation of open-ended, clustering, and discrete choice methods for user requirements development in a low-income country context

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Development engineering 2023年 8卷

作者： Sabet Sarvestani, Amir Gonzalez, Richard Johnson, Timothy R.B. Coulentianos, Marianna J. Sienko, Kathleen H. Design Science Program University of Michigan 1075 Beal Ave Ann ArborMI48109 United States Department of Psychology University of Michigan 530 Church St. Ann ArborMI48109 United States Department of Obstetrics & Gynecology Medical School University of Michigan L4000 Women's SPC 5276 Ann ArborMI48109 United States School of Design and Creative Arts Loughborough University LoughboroughLE11 3TU United Kingdom Department of Mechanical Engineering University of Michigan 2350 Hayward St. G.G. Brown Ann ArborMI48109 United States

High quality user requirements are positively correlated with successful design outcomes, but engaging stakeholders within low-income contexts can present financial and time-related challenges to product developers from non-local industrial and academic institutions with limited knowledge of the context. Existing literature provides guidance for engaging stakeholders during the early stages of product design in high-income country contexts, but few studies have examined the effectiveness of these methods in low-income country contexts. This study evaluated three user requirements elicitation and prioritization methods including open-ended, clustering, and discrete choice. Ghanaian healthcare delivery stakeholders with varying types of expertise, years of experience, and from various types of healthcare facilities were recruited to allow for diversity of responses. Participants included physicians (n = 10), nurses/midwives (n = 16), biomedical technicians (n = 14), and public health officers (n = 7). A hypothetical mechanical device for managing and treating postpartum hemorrhage was chosen to characterize each method's ability to elicit and prioritize user requirements. The open-ended method captured general requirements of a design concept, yet resulted in predominantly generic requirements. The results from the open-ended method were used to inform the clustering and discrete choice methods. The clustering and discrete choice methods were useful for inferring in-depth user requirements and eliciting stakeholder priorities. The clustering method revealed that usability and affordability were high-priority requirements among all four stakeholder groups. An individual difference scaling analysis was performed using the clustering method outcomes, which indirectly identified ease-of-use, availability, and effectiveness as the priority user requirements categories. Stakeholders ranked ease-of-use as the highest-priority user requirement, followed by performance, cost,

关键词： Product design

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The development of virtual laboratory on fluid materials 6

The development of virtual laboratory on fluid materials

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6th International Seminar on Mathematics, Science, and Computer Science Education, MSCEIS 2018

作者： Jannati, E.D. Setiawan, A. Siahaan, P. Rochman, C. Susanti, D. Samantha, Y. Mechanical Engineering Study Program Majalengka University Majalengka Indonesia Department of Mechanical Engineering Education Universitas Pendidikan Indonesia Bandung Indonesia Department of Physics Education Universitas Pendidikan Indonesia Bandung Indonesia Department of Physics Education UIN Sunan Gunung Djati Bandung Indonesia Department of Informatics Engineering Majalengka University Majalengka Indonesia

This study aims to study the development of laboratory learning media on the concept of fluids. The method used in this study is the research and development (R & D) method of implementation up to step 7, namely: (1) literature study, (2) needs analysis, (3) design of virtual lab learning media, (4) development of lab learning media virtual, (5) validation, (6) product testing, (7) product revision. Virtual laboratory learning media, have gone through a phase validation test by two material experts and one media expert who showed that laboratory learning media on fluid materials are feasible to be applied in learning. the results of sponsored pretest and posttest for students showed a significant increase. Recommended to be applied in a virtual learning laboratory is suitable to be applied in the Faculty of engineering, Majalengka University. © 2019 IOP Publishing Ltd.

关键词： Laboratories

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Design and Analysis of Minimally Invasive Surgical Robot

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IOP Conference Series: Materials Science and engineering 2021年第1期1132卷

作者： Ch. V S N Vasundhara A P Sudheer Mechatronics/Robotics Lab Department of Mechanical Engineering National Institute of Technology Calicut Kerala India

Minimally Invasive Surgical robots are commonly seen in medical centres for surgical purposes. However, the major challenges seen with such robotic systems are its heavy weight, costly and lack of capability to reconfigure according to the patient-specific needs. In this paper, a robot is proposed to overcome the difficulties with existing robotic systems. Six different concepts are proposed in this paper which are modelled in SolidWorks software. The best design has been selected using the concept scoring technique. Besides, the forward and inverse kinematics for the best concept is achieved using the Denavit-Hartenberg (D-H) modelling technique. Finally, results obtained from the analytical model has been verified using Peter Corke Toolbox in MATLAB. The trajectory planning of the selected concept has be done using the third-order polynomial equation and it is plotted using MATLAB.

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Modelling of torso and dual arms for a humanoid robot with fixed base by using screw theory for dexterous applications

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IOP Conference Series: Materials Science and engineering 2021年第1期1132卷

作者： Shifa Sulaiman A P Sudheer Mechatronics/Robotics Laboratory Department of Mechanical Engineering National Institute of technology Calicut Kerala India

Most of the humanoid robots are facing problems due to non-dexterous arms while working in complex environments. Kinematic and dexterity analyses help to study and solve the manipulation difficulties of a robot. This paper presents the kinematic and dexterity analyses of torso and dual arms for a tree type upper body humanoid robot with fixed base using screw theory formulation. Orientation workspace and reachability analyses of the dual arms are done for determining the dexterity of the robot. In this paper, orientation workspace of the tree type upper body is obtained by converting the rotation matrix to Euler angle set representation. The upper body of the humanoid robot is designed with three Degrees of freedom (DoF) in the torso, two DoF in the neck, five DoF in each arm.

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Light-driven C-H activation mediated by 2D transition metal dichalcogenides

arXiv

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arXiv 2022年

作者： Li, Jingang Zhang, Di Guo, Zhongyuan Jiang, Xi Larson, Jonathan M. Zhu, Haoyue Zhang, Tianyi Gu, Yuqian Blankenship, Brian Chen, Min Wu, Zilong Huang, Suichu Kostecki, Robert Minor, Andrew M. Grigoropoulos, Costas P. Akinwande, Deji Terrones, Mauricio Redwing, Joan M. Li, Hao Zheng, Yuebing Materials Science & Engineering Program Texas Materials Institute Walker Department of Mechanical Engineering The University of Texas at Austin AustinTX78712 United States Laser Thermal Laboratory Department of Mechanical Engineering University of California BerkeleyCA94720 United States Tohoku University Sendai980-8577 Japan Materials Sciences Division Lawrence Berkeley National Laboratory BerkeleyCA94720 United States Department of Chemistry and Biochemistry Baylor University WacoTX76798 United States Department of Materials Science and Engineering The Pennsylvania State University University ParkPA16802 United States Chandra Family Department of Electrical & Computer Engineering The University of Texas at Austin AustinTX78712 United States Department of Materials Science and Engineering University of California BerkeleyCA94720 United States Energy Storage and Distributed Resources Division Lawrence Berkeley National Laboratory BerkeleyCA94720 United States National Center for Electron Microscopy Molecular Foundry Lawrence Berkeley National Laboratory BerkeleyCA94720 United States Center for Two-Dimensional and Layered Materials The Pennsylvania State University University ParkPA16802 United States Department of Physics Department of Chemistry The Pennsylvania State University University ParkPA16802 United States 2D Crystal Consortium Materials Research Institute The Pennsylvania State University University ParkPA16802 United States

C-H bond activation enables the facile synthesis of new chemicals. While C-H activation in short-chain alkanes has been widely investigated, it remains largely unexplored for long-chain organic molecules. Here, we report light-driven C-H activation in complex organic materials mediated by 2D transition metal dichalcogenides (TMDCs) and the resultant solid-state synthesis of luminescent carbon dots in a spatially-resolved fashion. We unravel the efficient H adsorption and a lowered energy barrier of C-C coupling mediated by 2D TMDCs to promote C-H activation. Our results shed light on 2D materials for C-H activation in organic compounds for applications in organic chemistry, environmental remediation, and photonic materials. © 2022, CC BY-NC-SA.

关键词： Chemical activation

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Reconstruction of 3d human lymphatic vessel within tumor immune microenvironment using high-throughput platform 24

Reconstruction of 3d human lymphatic vessel within tumor imm...

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24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020

作者： Kang, Habin Lee, Somin Park, Dohyun Yu, James Koh, Seung Kwon Cho, Duck Kim, Da-Hyun Kang, Kyung-Sun Jeon, Noo Li Interdisciplinary Program for Bioengineering Seoul National University Korea Republic of Department of Mechanical Engineering Seoul National University Korea Republic of Department of Health Sciences and Technology Sungkyunkwan University Korea Republic of Adult Stem Cell Research Center Research Institute for Veterinary Science Seoul National University Korea Republic of

ISBN: (纸本)9781733419017

In this study, we established a 3D in vitro model of human lymphatic vessel (LV) within tumor immune microenvironment (TIME) using an injection-molded plastic array culture platform. Our platform enabled robust and reproducible formation of self-organized LV within the TIME in vitro. Using this co-culture model, we could (1) recapitulate cancer cell type-dependent morphogenesis of LV in vitro, (2) assess the effect of anti-VEGFR3 drug depending on the existence of blood vessels or different types of cancer cells through high-content analysis, and (3) design a trans-endothelial migration assay of cytotoxic primary lymphocytes within reconstructed melanoma TIME. © 2020 CBMS-0001

关键词： Cancer cells

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Multi-parameter prediction of oil palm fruit quality through near infrared spectroscopy combined with chemometric analysis

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Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2025年 343卷 126505页

作者： Muhammad Achirul Nanda Kharistya Amaru S. Rosalinda Inna Novianty Tusan Park Department of Agricultural and Biosystem Engineering Faculty of Agro-Industrial Technology Universitas Padjadjaran Sumedang 45363 Indonesia Computer Engineering Technology Study Program College of Vocational Studies IPB University Bogor 16680 Indonesia Department of Smart Bio-Industrial Mechanical Engineering Kyungpook National University Daegu 41566 Republic of Korea Department of Applied Biosciences Kyungpook National University Daegu 41566 Republic of Korea Smart Agriculture Innovation Center Kyungpook National University Daegu 41566 Republic of Korea

Early information concerning water, oil, and free fatty acid (FFA) content in palm fruit on-site is crucial in determining the commercial value of fresh fruit bunches (FFB) and maintaining oil palm quality. Conventional methods are destructive, labor-intensive, single-target, costly, and time-consuming. Therefore, this study aimed to develop a method for the multi-parameter prediction of oil palm fruit quality using near-infrared (NIR) spectroscopy. Empirical Wavelet Transform (EWT) and Gaussian Process Regression (GPR) were implemented as a novel chemometric method. A total of 750 fruit samples of the Tenera variety ( Elaeis guineensis Jacq. var. tenera) with various maturity levels were collected from the Cikabayan Oil Palm Plantation. Each sample was scanned using an NIR instrument at 1000–1500 nm wavelengths to obtain absorbance data. The EWT was applied to decompose the NIR spectra into empirical modes, and GPR was used to build a regression model for fitting. Based on numerical analysis, the combination of EWT and GPR produced the root mean square error (RMSE) values of 2.877 ± 0.900 % (R 2 = 0.955 ± 0.018), 1.256 ± 0.543 % (R 2 = 0.942 ± 0.030), and 0.065 ± 0.04 % (R 2 = 0.964 ± 0.044) for water, oil, and FFA content, respectively. The results showed that the model could accurately predict the internal quality of oil palm fruit without the need for solvents or reagents, supporting environmental sustainability. These were expected to enhance oil palm production management by improving quality control, optimizing harvest timing, and promoting sustainability across the value chain.

关键词： Chemometric Near-infrared spectroscopy Nondestructive evaluation Oil palm fruit Quality

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Reconfigurable design for omni-adaptive grasp learning*

arXiv

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arXiv 2020年

作者： Wan, Fang Wang, Haokun Wu, Jiyuan Liu, Yujia Ge, Sheng Song, Chaoyang AncoraSpring SUSTech Institute of Robotics Southern University of Science and Technology Shenzhen Guangdong518055 China Department of Mechanical and Energy Engineering Southern University of Science and Technology Shenzhen Guangdong518055 China Department of Mechanical and Energy Engineering Southern University of Science and Technology Shenzhen Guangdong518055 China

— The engineering design of robotic grippers presents an ample design space for optimization towards robust grasping. In this paper, we adopt the reconfigurable design of the robotic gripper using a novel soft finger structure with omni-directional adaptation, which generates a large number of possible gripper configurations by rearranging these fingers. Such reconfigurable design with these omni-adaptive fingers enables us to systematically investigate the optimal arrangement of the fingers towards robust grasping. Furthermore, we adopt a learning-based method as the baseline to benchmark the effectiveness of each design configuration. As a result, we found that a 3-finger and 4-finger radial configuration is the most effective one achieving an average 96% grasp success rate on seen and novel objects selected from the YCB dataset. We also discussed the influence of the frictional surface on the finger to improve the grasp robustness. Copyright © 2020, The Authors. All rights reserved.

关键词： Grippers

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