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Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

Nature communications 2024年第1期15卷 2364页

作者： Celina Tretter Niklas de Andrade Krätzig Matteo Pecoraro Sebastian Lange Philipp Seifert Clara von Frankenberg Johannes Untch Gabriela Zuleger Mathias Wilhelm Daniel P Zolg Florian S Dreyer Eva Bräunlein Thomas Engleitner Sebastian Uhrig Melanie Boxberg Katja Steiger Julia Slotta-Huspenina Sebastian Ochsenreither Nikolas von Bubnoff Sebastian Bauer Melanie Boerries Philipp J Jost Kristina Schenck Iska Dresing Florian Bassermann Helmut Friess Daniel Reim Konrad Grützmann Katrin Pfütze Barbara Klink Evelin Schröck Bernhard Haller Bernhard Kuster Matthias Mann Wilko Weichert Stefan Fröhling Roland Rad Michael Hiltensperger Angela M Krackhardt German Cancer Consortium (DKTK) partner site Munich and German Cancer Research Center (DKFZ) Heidelberg Germany. Technical University of Munich TUM School of Medicine Klinikum rechts der Isar IIIrd Medical Department Munich Germany. Technical University of Munich TUM School of Medicine Klinikum rechts der Isar IInd Medical Department Munich Germany. Technical University of Munich TUM School of Medicine Center for Translational Cancer Research (TranslaTUM) Munich Germany. Technical University of Munich TUM School of Medicine Institute of Molecular Oncology and Functional Genomics Munich Germany. Department of Proteomics and Signal Transduction Max Plank Institute of Biochemistry Munich Germany. Institute for Research in Biomedicine Università della Svizzera italiana Bellinzona Switzerland. Technical University of Munich TUM School of Life Sciences Chair of Proteomics and Bioanalytics Freising Germany. Technical University of Munich TUM School of Life Sciences Computational Mass Spectrometry Freising Germany. German Cancer Consortium (DKTK) partner site Heidelberg and German Cancer Research Center (DKFZ) Heidelberg Germany. Molecular Precision Oncology Program NCT Heidelberg Heidelberg Germany. Technical University of Munich TUM School of Medicine Klinikum rechts der Isar Institute of Pathology Munich Germany. German Cancer Consortium (DKTK) partner site Berlin and German Cancer Research Center (DKFZ) Heidelberg Germany. Charité Comprehensive Cancer Center Charité - Universitätsmedizin Berlin Berlin Germany. Department of Hematology Oncology and Tumor Immunology Charité - Universitätsmedizin Berlin Berlin Germany. German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ) Heidelberg Germany. Institute of Medical Bioinformatics and Systems Medicine (IBSM) Medical Center - University of Freiburg Faculty of Medicine University of Freiburg Freiburg Germany. Department of Hematology and Oncology Medical Center Universit

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Molecular landscape of sex- and modality-specific exercise adaptation in human skeletal muscle through large-scale multi-omics integration

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Cell Reports 2025年第6期44卷 115750页

作者： Macsue Jacques Shanie Landen Adam P. Sharples Andrew Garnham Ralf Schittenhelm Joel Steele Aino Heikkinen Elina Sillanpää Miina Ollikainen James Broatch Navabeh Zarekookandeh Ola Hanson Ola Ekström Olof Asplund Séverine Lamon Sarah E. Alexander Cassandra Smith Carlie Bauer Mary N. Woessner Itamar Levinger Andrew E. Teschendorff Linn Gillberg Ida Blom Jørn Wulff Helge Nicholas R. Harvey Larisa M. Haupt Lyn R. Griffiths Atul S. Deshmukh Kirsi H. Pietiläinen Päivi Piirilä Robert A.E. Seaborne Marie Klevjer Anja Bye Ulrik Wisløff Bernadette Jones-Freeman Nir Eynon Australian Regenerative Medicine Institute Monash University Clayton VIC Australia Institute for Health and Sport (iHeS) Victoria University Footscray VIC Australia Centre for Endocrinology and Metabolism Hudson Institute of Medical Research Melbourne VIC Australia Institute of Physical Performance Norwegian School of Sport Sciences Oslo Norway Monash Proteomics & Metabolomics Platform Monash Biomedicine Discovery Institute Monash University Melbourne VIC Australia Institute for Molecular Medicine Finland (FIMM) Helsinki University Helsinki Finland Faculty of Sport and Health Sciences University of Jyväskylä Jyväskylä Finland Wellbeing Services County of Central Finland Jyväskylä Finland Minerva Foundation Institute for Medical Research Helsinki Finland Department of Clinical Sciences Translational Muscle Research Unit Lund University Diabetes Center Lund University Lund Sweden Institute for Physical Activity and Nutrition (IPAN) School of Exercise and Nutrition Sciences Deakin University 221 Burwood Highway Burwood VIC 3125 Australia Cardiometabolic Health and Exercise Physiology Laboratory Baker Heart and Diabetes Institute 75 Commercial Road Melbourne VIC 3004 Australia Nutrition & Health Innovation Research Institute Edith Cowan University Joondalup WA Australia Medical School The University of Western Australia Perth WA Australia Australian Institute for Musculoskeletal Science (AIMSS) Victoria University Melbourne VIC Australia CAS Key Lab of Computational Biology Shanghai Institute of Nutrition and Health Shanghai China Department of Biomedical Sciences University of Copenhagen Copenhagen Denmark Faculty of Health Sciences and Medicine Bond University Gold Coast QLD Australia Genomics Research Centre Centre for Genomics and Personalised Health School of Biomedical Sciences Queensland University of Technology Brisbane QLD Australia ARC Training Centre for Cell and Tissue Engineering Technologies Queensland University of Technology (Q

We investigated the molecular mechanisms of exercise adaptations in human muscle by integrating genome, methylome, transcriptome, and proteome data from over 1,000 participants (2,340 muscle samples). We identified distinctive signatures associated with maximal oxygen consumption (VO2max), and multi-omics integration uncovered five key genes as robust exercise markers across layers, with transcription factors functioning as activators, synergizing with DNA methylation to regulate gene expression. Minimal sex differences were observed, while modality-specific analysis highlighted distinct pathways for aerobic and resistance exercise, contrasting with muscle disuse patterns. Finally, we created a webtool, OMAx, featuring our individual omics and integration analysis. These findings provide a comprehensive multi-omics framework for understanding exercise-induced molecular adaptations, offering insights into muscle health, cardiorespiratory fitness, and their roles in aging and disease prevention.

关键词： skeletal muscle Multi Omics epigenetics DNA methylation exercise VO2 max gene expression transcriptomic proteomic

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Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study

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Translational psychiatry 2024年第1期14卷 109页

作者： Anna H Ou Sara B Rosenthal Mazda Adli Kazufumi Akiyama Nirmala Akula Martin Alda Azmeraw T Amare Raffaella Ardau Bárbara Arias Jean-Michel Aubry Lena Backlund Michael Bauer Bernhard T Baune Frank Bellivier Antonio Benabarre Susanne Bengesser Abesh Kumar Bhattacharjee Joanna M Biernacka Pablo Cervantes Guo-Bo Chen Hsi-Chung Chen Caterina Chillotti Sven Cichon Scott R Clark Francesc Colom David A Cousins Cristiana Cruceanu Piotr M Czerski Clarissa R Dantas Alexandre Dayer Maria Del Zompo Franziska Degenhardt J Raymond DePaulo Bruno Étain Peter Falkai Frederike Tabea Fellendorf Ewa Ferensztajn-Rochowiak Andreas J Forstner Louise Frisén Mark A Frye Janice M Fullerton Sébastien Gard Julie S Garnham Fernando S Goes Maria Grigoroiu-Serbanescu Paul Grof Oliver Gruber Ryota Hashimoto Joanna Hauser Urs Heilbronner Stefan Herms Per Hoffmann Andrea Hofmann Liping Hou Stephane Jamain Esther Jiménez Jean-Pierre Kahn Layla Kassem Tadafumi Kato Sarah Kittel-Schneider Barbara König Po-Hsiu Kuo Ichiro Kusumi Nina Lackner Gonzalo Laje Mikael Landén Catharina Lavebratt Marion Leboyer Susan G Leckband Carlos A López Jaramillo Glenda MacQueen Mario Maj Mirko Manchia Cynthia Marie-Claire Lina Martinsson Manuel Mattheisen Michael J McCarthy Susan L McElroy Francis J McMahon Philip B Mitchell Marina Mitjans Francis M Mondimore Palmiero Monteleone Caroline M Nievergelt Markus M Nöthen Tomas Novák Urban Ösby Norio Ozaki Sergi Papiol Roy H Perlis Claudia Pisanu James B Potash Andrea Pfennig Daniela Reich-Erkelenz Andreas Reif Eva Z Reininghaus Marcella Rietschel Guy A Rouleau Janusz K Rybakowski Martin Schalling Peter R Schofield K Oliver Schubert Thomas G Schulze Barbara W Schweizer Florian Seemüller Giovanni Severino Tatyana Shekhtman Paul D Shilling Kazutaka Shimoda Christian Simhandl Claire M Slaney Alessio Squassina Thomas Stamm Pavla Stopkova Sarah K Tighe Alfonso Tortorella Gustavo Turecki Eduard Vieta Julia Volkert Stephanie Witt Naomi R Wray Adam Wright L Trevor Young Peter P Zandi John R Kelsoe Department of Psychiatry University of California San Diego La Jolla CA USA. Center for Computational Biology and Bioinformatics Department of Medicine University of California San Diego La Jolla CA USA. Department of Psychiatry and Psychotherapy Charité- Universitätsmedizin Berlin Campus Charité Mitte Berlin Germany. Fliedner Klinik Berlin Center for Psychiatry Psychotherapy and Psychosomatic Medicine Berlin Germany. Department of Biological Psychiatry and Neuroscience Dokkyo Medical University School of Medicine Mibu Japan. Intramural Research Program National Institute of Mental Health National Institutes of Health US Department of Health & Human Services Bethesda MD USA. Department of Psychiatry Dalhousie University Halifax NS Canada. National Institute of Mental Health Klecany Czech Republic. Discipline of Psychiatry University of Adelaide Adelaide SA Australia. Unit of Clinical Pharmacology Hospital University Agency of Cagliari Cagliari Italy. Department of Evolutive Biology Ecology and Environmental Sciences Facultat de Biologia and Institut de Biomedicina (IBUB) Universitat de Barcelona Barcelona Spain. CIBER de Salud Mental ISCIII Madrid Barcelona Catalonia Spain. Department of Mental Health and Psychiatry Mood Disorders Unit-Geneva University Hospitals Geneva Switzerland. Department of Molecular Medicine and Surgery Karolinska Institutet and Center for Molecular Medicine Karolinska University Hospital Stockholm Sweden. Department of Psychiatry and Psychotherapy University Hospital Carl Gustav Carus Medical Faculty Technische Universität Dresden Dresden Germany. Department of Psychiatry University of Münster Münster Germany. INSERM UMR-S 1144-Université Paris Cité Département de Psychiatrie et de Médecine Addictologique AP-HP Groupe Hospitalier Lariboisière-F Widal Paris France. Bipolar and Depressive Disorders Unit Institute of Neuroscience Hospital Clinic University of Barcelona IDIBAPS CIBERSAM ISCIII Barcelona Catalonia Spa

Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study of the Pharmacogenomics of Bipolar Disorder (PGBD) sample combining transcriptomic and genomic data, we found that focal adhesion, the extracellular matrix (ECM), and PI3K-Akt signaling networks were associated with response to lithium. In this study, we replicated the results of our previous study using network propagation methods in a genome-wide association study of an independent sample of 2039 patients from the International Consortium on Lithium Genetics (ConLiGen) study. We identified functional enrichment in focal adhesion and PI3K-Akt pathways, but we did not find an association with the ECM pathway. Our results suggest that deficits in the neuronal growth cone and PI3K-Akt signaling, but not in ECM proteins, may influence response to lithium in BD.

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids

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Nature 2023年第7965期618卷 E19-E20页

作者： Sarah E Graham Shoa L Clarke Kuan-Han H Wu Stavroula Kanoni Greg J M Zajac Shweta Ramdas Ida Surakka Ioanna Ntalla Sailaja Vedantam Thomas W Winkler Adam E Locke Eirini Marouli Mi Yeong Hwang Sohee Han Akira Narita Ananyo Choudhury Amy R Bentley Kenneth Ekoru Anurag Verma Bhavi Trivedi Hilary C Martin Karen A Hunt Qin Hui Derek Klarin Xiang Zhu Gudmar Thorleifsson Anna Helgadottir Daniel F Gudbjartsson Hilma Holm Isleifur Olafsson Masato Akiyama Saori Sakaue Chikashi Terao Masahiro Kanai Wei Zhou Ben M Brumpton Humaira Rasheed Sanni E Ruotsalainen Aki S Havulinna Yogasudha Veturi QiPing Feng Elisabeth A Rosenthal Todd Lingren Jennifer Allen Pacheco Sarah A Pendergrass Jeffrey Haessler Franco Giulianini Yuki Bradford Jason E Miller Archie Campbell Kuang Lin Iona Y Millwood George Hindy Asif Rasheed Jessica D Faul Wei Zhao David R Weir Constance Turman Hongyan Huang Mariaelisa Graff Anubha Mahajan Michael R Brown Weihua Zhang Ketian Yu Ellen M Schmidt Anita Pandit Stefan Gustafsson Xianyong Yin Jian'an Luan Jing-Hua Zhao Fumihiko Matsuda Hye-Mi Jang Kyungheon Yoon Carolina Medina-Gomez Achilleas Pitsillides Jouke Jan Hottenga Gonneke Willemsen Andrew R Wood Yingji Ji Zishan Gao Simon Haworth Ruth E Mitchell Jin Fang Chai Mette Aadahl Jie Yao Ani Manichaikul Helen R Warren Julia Ramirez Jette Bork-Jensen Line L Kårhus Anuj Goel Maria Sabater-Lleal Raymond Noordam Carlo Sidore Edoardo Fiorillo Aaron F McDaid Pedro Marques-Vidal Matthias Wielscher Stella Trompet Naveed Sattar Line T Møllehave Betina H Thuesen Matthias Munz Lingyao Zeng Jianfeng Huang Bin Yang Alaitz Poveda Azra Kurbasic Claudia Lamina Lukas Forer Markus Scholz Tessel E Galesloot Jonathan P Bradfield E Warwick Daw Joseph M Zmuda Jonathan S Mitchell Christian Fuchsberger Henry Christensen Jennifer A Brody Mary F Feitosa Mary K Wojczynski Michael Preuss Massimo Mangino Paraskevi Christofidou Niek Verweij Jan W Benjamins Jorgen Engmann Rachel L Kember Roderick C Slieker Ken Sin Lo Nuno R Zilhao Phuong Le Marcus E Kleber Graciela E Delgado Shaofeng Huo Dai Department of Internal Medicine Division of Cardiology University of Michigan Ann Arbor MI USA. VA Palo Alto Health Care System Palo Alto CA USA. Department of Medicine Division of Cardiovascular Medicine Stanford University School of Medicine Stanford CA USA. Department of Computational Medicine and Bioinformatics University of Michigan Ann Arbor MI USA. William Harvey Research Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK. Department of Biostatistics and Center for Statistics Genetics University of Michigan Ann Arbor MI USA. Department of Genetics Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Clinical Pharmacology William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK. Endocrinology Boston Children's Hospital Boston MA USA. Medical and Population Genetics Broad Institute Cambridge MA USA. Department of Genetic Epidemiology University of Regensburg Regensburg Germany. McDonnell Genome Institute and Department of Medicine Washington University St Louis MO USA. Department of Precision Medicine Division of Genome Science National Institute of Health Cheongju-si South Korea. Tohoku Medical Megabank Organization Tohoku University Sendai Japan. Sydney Brenner Institute for Molecular Bioscience Faculty of Health Sciences University of the Witwatersrand Johannesburg South Africa. Center for Research on Genomics and Global Health National Human Genome Research Institute National Institutes of Health Bethesda MD USA. Blizard Institute Barts and the London School of Medicine and Dentistry Queen Mary University of London London UK. Wellcome Sanger Institute Hinxton UK. Department of Epidemiology Emory University Rollins School of Public Health Atlanta GA USA. Atlanta VA Health Care System Decatur GA USA. Malcolm Randall VA Medical Center Gainesville FL USA. Division of Vascular Sur

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Mass spectrometry based proteomics profiling of human monocytes

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Protein & Cell 2017年第2期8卷 123-133页

作者： Yong Zeng Fei-Yan Deng Wei Zhu Lan Zhang Hao He Chao Xu Qing Tian Ji-Gang Zhang Li-Shu Zhang Hong-Gang Hu Hong-Wen Deng College of Life Sciences and Bioengineering Beijing Jiaotong University Beijing 100044 China Center of Bioinformatics and Genomics Tulane University School of Public Health and Tropical Medicine New Orleans LA 70112 USA College of Life Sciences Hunan Normal University Changsha 410081 China Laboratory of Proteins and Proteomics Department of Epidemiology Soochow University School of Public Health Suzhou 205123 China

Human monocyte is an important cell type which is involved in various complex human diseases. To better understand the biology of human monocytes and facilitate further studies, we developed the first comprehensive proteome knowledge base specifically for human monocytes by integrating both in vivo and in vitro datasets. The top 2000 expressed genes from in vitro datasets and 779 genes from in vivo experiments were integrated into this study. Altogether, a total of 2237 unique monocyte-expressed genes were cataloged. Biological functions of these monocyte-expressed genes were annotated and classified via Gene Ontology （GO） analysis. Furthermore, by extracting the overlapped genes from in vivo and in vitro datasets, a core gene list including 541 unique genes was generated. Based on the core gene list, further gene-disease associations, pathway and network analyses were performed. Data analyses based on multiple bioinformatics tools produced a large body of biologically meaningful information, and revealed a number of genes such as SAMHDI, G6PD, GPD2 and EN01, which have been reported to be related to immune response, blood biology, bone remodeling, and cancer respectively. As a unique resource, this study can serve as a reference map for future in-depth research on monocytes biology and monocyte-involved human diseases.

关键词： human monocytes proteomics knowledgebase gene ontology gene-disease association network analysis

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Correction to: The International Mouse Phenotyping Consortium (IMPC): a functional catalogue of the mammalian genome that informs conservation

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Conservation Genetics 2019年第1期20卷 135-136页

作者： Violeta Muñoz-Fuentes Pilar Cacheiro Terrence F. Meehan Juan Antonio Aguilar-Pimentel Arthur L. Beaudet Steve D. M. Brown Mary E. Dickinson Ann M. Flenniken Paul Flicek Antonella Galli Hamed Haseli Mashhadi Jason D. Heaney Martin Hrabě de Angelis Jong Kyoung Kim K. C. Kent Lloyd Colin McKerlie Hugh Morgan Stephen A. Murray Lauryl M. J. Nutter Patrick T. Reilly John R. Seavitt Je Kyung Seong Michelle Simon Hannah Wardle-Jones Ann-Marie Mallon Damian Smedley Helen E. Parkinson European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Cambridge UK Clinical Pharmacology William Harvey Research Institute School of Medicine and Dentistry Queen Mary University of London London UK German Mouse Clinic Institute of Experimental Genetics Helmholtz Zentrum München German Research Center for Environmental Health Neuherberg Germany Department of Molecular and Human Genetics Baylor College of Medicine Houston USA Medical Research Council Harwell Institute (Mammalian Genetics Unit and Mary Lyon Centre) Harwell UK Department of Molecular Physiology and Biophysics Baylor College of Medicine Houston USA The Centre for Phenogenomics Toronto Canada Mount Sinai Hospital Toronto Canada Wellcome Trust Sanger Institute Cambridge UK German Center for Diabetes Research (DZD) Neuherberg Germany School of Life Science Weihenstephan Technische Universität München Freising Germany Department of New Biology DGIST Daegu Republic of Korea Mouse Biology Program University of California Davis USA The Hospital for Sick Children Toronto Canada The Jackson Laboratory Bar Harbor USA PHENOMIN-iCS Illkirch Cedex France Laboratory of Developmental Biology and Genomics College of Veterinary Medicine Interdisciplinary Program for Bioinformatics and Program for Cancer Biology Seoul National University Seoul Republic of Korea

The original publication of this article unfortunately contained the following mistakes.

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Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution (vol 33, pg 568, 2020)

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NATURE GENETICS 2020年第4期52卷 463-463页

作者： Chan-Seng-Yue, Michelle Kim, Jaeseung C. Wilson, Gavin W. Ng, Karen Figueroa, Eugenia Flores O'Kane, Grainne M. Connor, Ashton A. Denroche, Robert E. Grant, Robert C. McLeod, Jessica Wilson, Julie M. Jang, Gun Ho Zhang, Amy Liang, Sheng-Ben Borgida, Ayelet Chadwick, Dianne Kalimuthu, Sangeetha Lungu, Ilinca Bartlett, John M. S. Krzyzanowski, Paul M. Sandhu, Vandana Tiriac, Herve Froeling, Fieke E. M. Karasinska, Joanna M. Topham, James T. Renouf, Daniel J. Schaeffer, David F. Jones, Steven J. M. Marra, Marco A. Laskin, Janessa Chetty, Runjan Stein, Lincoln D. Zogopoulos, George Haibe-Kains, Benjamin Campbell, Peter J. Tuveson, David A. Knox, Jennifer J. Fischer, Sandra E. Gallinger, Steven Notta, Faiyaz Princess Margaret Cancer Centre Toronto Ontario Canada PanCuRx Translational Research Initiative Ontario Institute for Cancer Research Toronto Ontario Canada Genomics Technology Program Ontario Institute for Cancer Research Toronto Ontario Canada Wallace McCain Centre for Pancreatic Cancer Department of Medical Oncology Princess Margaret Centre University Health Network University of Toronto Toronto Ontario Canada Hepatobiliary/Pancreatic Surgical Oncology Program University Health Network Toronto Ontario Canada UHN Program in BioSpecimen Sciences University Health Network Toronto Ontario Canada Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital Toronto Ontario Canada Department of Pathology University Health Network and University of Toronto Toronto Ontario Canada Diagnostic Development Ontario Institute for Cancer Research Toronto Ontario Canada Cold Spring Harbor Laboratory Cold Spring Harbor NY USA Lustgarten Foundation Pancreatic Cancer Research Laboratory Cold Spring Harbor NY USA Department of Surgery and Cancer Imperial College London London UK Pancreas Centre BC Vancouver British Columbia Canada Department of Medical Oncology BC Cancer Vancouver British Columbia Canada Department of Pathology and Laboratory Medicine Vancouver General Hospital Vancouver British Columbia Canada Canada’s Michael Smith Genome Sciences Centre Vancouver British Columbia Canada Department of Medical Genetics University of British Columbia Vancouver British Columbia Canada Bioinformatics Ontario Institute for Cancer Research Toronto Ontario Canada Department of Molecular Genetics University of Toronto Toronto Ontario Canada Research Institute of the McGill University Health Centre Montreal Quebec Canada The Goodman Cancer Research Centre of McGill University Montreal Quebec Canada Department of Medical Biophysics University of Toronto Toronto Ontario Canada Department of Computer Science University of Toronto Toronto Ontario Canada Can

Pancreatic adenocarcinoma presents as a spectrum of a highly aggressive disease in patients. The basis of this disease heterogeneity has proved difficult to resolve due to poor tumor cellularity and extensive genomic instability. To address this, a dataset of whole genomes and transcriptomes was generated from purified epithelium of primary and metastatic tumors. Transcriptome analysis demonstrated that molecular subtypes are a product of a gene expression continuum driven by a mixture of intratumoral subpopulations, which was confirmed by single-cell analysis. Integrated whole-genome analysis uncovered that molecular subtypes are linked to specific copy number aberrations in genes such as mutant KRAS and GATA6. By mapping tumor genetic histories, tetraploidization emerged as a key mutational process behind these events. Taken together, these data support the premise that the constellation of genomic aberrations in the tumor gives rise to the molecular subtype, and that disease heterogeneity is due to ongoing genomic instability during progression.

关键词： Pancreatic cancer Transcriptomics

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Erratum for Wang et al., "Clinically Applicable System for Rapidly Predicting Enterococcus faecium Susceptibility to Vancomycin"

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Microbiology spectrum 2022年第1期10卷 e0261021页

作者： Hsin-Yao Wang Chia-Ru Chung Chao-Jung Chen Ko-Pei Lu Yi-Ju Tseng Tzu-Hao Chang Min-Hsien Wu Wan-Ting Huang Ting-Wei Lin Tsui-Ping Liu Tzong-Yi Lee Jorng-Tzong Horng Jang-Jih Lu Department of Laboratory Medicine Chang Gung Memorial Hospitalgrid.413801.f at Linkou Taoyuan City Taiwan. Ph.D. Program in Biomedical Engineering Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Computer Science and Information Engineering National Central Universitygrid.37589.30 Taoyuan City Taiwan. Graduate Institute of Integrated Medicine China Medical Universitygrid.254145.3 Taichung Taiwan. Proteomics Core Laboratory China Medical Universitygrid.254145.3 Hospital Taichung Taiwan. Graduate Program in Biomedical Information Yuan-Ze University Taoyuan City Taiwan. Department of Information Management Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Graduate Institute of Biomedical Informatics Taipei Medical University Taipei City Taiwan. Clinical Big Data Research Center Taipei Medical University Hospital Taipei City Taiwan. Graduate Institute of Biomedical Engineering Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Division of Haematology/Oncology Department of Internal Medicine Chang Gung Memorial Hospitalgrid.413801.f at Linkou Taoyuan City Taiwan. Biosensor Group Biomedical Engineering Research Center Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Pathology Kaohsiung Chang Gung Memorial Hospitalgrid.413801.f and Chang Gung University College of Medicine Kaohsiung Taiwan. School of Life and Health Sciences The Chinese University of Hong Kong Shenzhen China. Warshel Institute for Computational Biology The Chinese University of Hong Kong Shenzhen China. Department of Bioinformatics and Medical Engineering Asia University Taichung City Taiwan. School of Medicine Chang Gung Universitygrid.145695.a Taoyuan City Taiwan. Department of Medical Biotechnology and Laboratory Science Chang Gung Universitygrid.145695.a Taoyuan City Taiwan.

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Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

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Nature genetics 2023年第6期55卷 1080页

作者： Bernardo Rodriguez-Martin Eva G Alvarez Adrian Baez-Ortega Jorge Zamora Fran Supek Jonas Demeulemeester Martin Santamarina Young Seok Ju Javier Temes Daniel Garcia-Souto Harald Detering Yilong Li Jorge Rodriguez-Castro Ana Dueso-Barroso Alicia L Bruzos Stefan C Dentro Miguel G Blanco Gianmarco Contino Daniel Ardeljan Marta Tojo Nicola D Roberts Sonia Zumalave Paul A Edwards Joachim Weischenfeldt Montserrat Puiggròs Zechen Chong Ken Chen Eunjung Alice Lee Jeremiah A Wala Keiran M Raine Adam Butler Sebastian M Waszak Fabio C P Navarro Steven E Schumacher Jean Monlong Francesco Maura Niccolo Bolli Guillaume Bourque Mark Gerstein Peter J Park David C Wedge Rameen Beroukhim David Torrents Jan O Korbel Iñigo Martincorena Rebecca C Fitzgerald Peter Van Loo Haig H Kazazian Kathleen H Burns Peter J Campbell Jose M C Tubio Department of Zoology Genetics and Physical Anthropology Universidade de Santiago de Compostela Santiago de Compostela Spain. Biomedical Research Centre (CINBIO) University of Vigo Vigo Spain. Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain. Transmissible Cancer Group Department of Veterinary Medicine University of Cambridge Cambridge UK. The Biomedical Research Centre (CINBIO) Universidade de Vigo Vigo Spain. Wellcome Sanger Institute Wellcome Genome Campus Cambridge UK. Genome Data Science Institute for Research in Biomedicine (IRB Barcelona) The Barcelona Institute of Science and Technology (BIST) Barcelona Spain. Institucio Catalana de Recerca i Estudis Avançats (ICREA) Barcelona Spain. The Francis Crick Institute London UK. Department of Human Genetics University of Leuven Leuven Belgium. Genomes and Disease Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain. Graduate School of Medical Science and Engineering Korea Advanced Institute of Science and Technology Daejeon South Korea. Cancer Ageing and Somatic Mutation Programme Wellcome Sanger Institute Cambridge UK. Department of Biochemistry Genetics and Immunology University of Vigo Vigo Spain. Galicia Sur Health Research Institute Vigo Spain. Faculty of Science and Technology University of Vic-Central University of Catalonia (UVic-UCC) Vic Spain. Barcelona Supercomputing Center (BSC) Barcelona Spain. Experimental Cancer Genetics Wellcome Sanger Institute Cambridge UK. Oxford Big Data Institute University of Oxford Oxford UK. DNA Repair and Genome Integrity Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain. Department of Biochemistry and Molecular Biology Universidade de Santiago de Compostela Santiago de Compostela Spain. Medical R

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Author Correction: Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts

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npj Genomic medicine 2023年第1期8卷 1页

作者： Giuliana Giannuzzi Nicolas Chatron Katrin Mannik Chiara Auwerx Sylvain Pradervand Gilles Willemin Jacqueline Chrast Eleonora Porcu Katrin Männik Alexandre Reymond Damien Sanlaville Caroline Schluth-Bolard Marie C. Sadler Zoltan Kutalik Kendra Hoekzema Evan E. Eichler Xander Nuttle Yann Herault Cédric Le Caignec Mathilde Nizon Bertrand Isidor Brigitte Gilbert-Dussardier Sandra Martin Sébastien Jacquemont Armand Bottani Marion Gérard Sacha Weber Aurélia Jacquette Catherine Vincent-Delorme Aurora Currò Francesca Mari Alessandra Renieri Alfredo Brusco Giovanni Battista Ferrero Center for Integrative Genomics University of Lausanne Lausanne Switzerland Department of Biosciences University of Milan Milan Italy Service de génétique Hospices Civils de Lyon Lyon France University of Lyon Université Claude Bernard Lyon 1 CNRS UMR-5310 INSERM U-1217 Institut NeuroMyoGène F-69008 Lyon France Department of Computational Biology University of Lausanne Lausanne Switzerland Center for Primary Care and Public Health University of Lausanne Lausanne Switzerland Swiss Institute of Bioinformatics Lausanne Switzerland Department of Genome Sciences University of Washington Seattle WA USA Howard Hughes Medical Institute University of Washington Seattle WA USA Center for Genomic Medicine Massachusetts General Hospital Boston MA USA Department of Neurology Harvard Medical School Boston MA USA Program in Medical and Population Genetics and Stanley Center for Psychiatric Research Broad Institute Cambridge MA USA University of Strasbourg CNRS INSERM PHENOMIN-ICS Institute of Genetics and Molecular and Cellular Biology Illkirch France Service de Génétique Médicale CHU de Nantes Nantes France Service de Génétique CHU de Poitiers Poitiers France Centre Hospitalier Universitaire Vaudois University of Lausanne Lausanne Switzerland University of Montreal Montreal Canada Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Service de Génétique Medicale CHU de Caen Caen France Service de Génétique Clinique CHU Paris-GH La Pitié Salpêtrière Paris France Service de Génétique Clinique CHU de Lille Lille France Medical Genetics University of Siena Siena Italy Department of Medical Sciences University of Turin Turin Italy Department of Clinical and Biological Sciences University of Turin Turin Italy

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