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Genetic variation of somaclonal mutants from the 8th generation of Pekalongan accession rodent tuber (typhonium flagelliforme lodd.) based on RAPD-PCR analysis 2

Genetic variation of somaclonal mutants from the 8th generat...

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2nd International Conference on Eco engineering Development 2018, ICEED 2018

作者： Purnamaningsih, Ragapadmi Sianipar, Nesti Fronika Assidqi, Khoirunnisa Spits Warnars, Harco Leslie Hendric Indonesia Center for Agricultural Biotechnology and Genetic Resources Research and Development Bogor16111 Indonesia Food Technology Department Faculty of Engineering Bina Nusantara University Jakarta11480 Indonesia Research Interest Group Food Biotechnology Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program - Doctor of Computer Science Bina Nusantara University Jakarta11480 Indonesia

Rodent tuber is a potential plant which can be developed as an anticancer drug. The rodent tuber plant has a low anticancer compound which does not have an economic value to be utilized on an industrial scale, particularly to explore as an anticancer drug. The material plant was used 30 clones of Rodent Tuber Pekalongan to increase its bioactive compounds using a combination of in vitro culture with gamma-ray irradiation. The selection process has been done until the 8th generation and obtained 14 somaclonal mutants that have higher bioactive compounds than control plant (non-mutant). This study aimed to analyze the genetic variation of 14 somaclonal mutants of rodent tuber using RAPD with 14 primers. The results were produced 513 total bands with the size of 200-5000 bp and 380 polymorphic bands between somaclonal mutants. OPB-18 primer produced the most polymorphic bands and five specific polymorphic bands of 1336 bp, 1070 bp, 901 bp, 861 bp and 728 bp in the somaclonal mutant M23 (20-4-2-1-1-1). OPD-20 primer produced seven specific polymorphic bands of 1574 bp, 1557 bp, 1501 bp, 1496 bp, 1234 bp, 1229 bp and 1086 bp in the M23 somaclonal mutant. The phylogenetic analysis showed that there were two main groups with the coefficient similarity between 0.77 and 0.83. The highest genetic variation obtained was found in the M23 somaclonal mutant with a genetic difference of 23% compared with control. There are five somaclonal mutants (M24, M22, M21, M16, M14) that have a genetic variation of up to 22% over the control. This study shows that OPB-18 and OPD-20 primers were efficient in detecting somaclonal mutant variants. © 2018 Institute of Physics Publishing. All rights reserved.

关键词： Gamma rays

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Lattice dynamics localization in low-angle twisted bilayer graphene

arXiv

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arXiv 2020年

作者： Gadelha, Andreij C. Ohlberg, Douglas A.A. Rabelo, Cassiano Neto, Eliel G.S. Vasconcelos, Thiago L. Campos, João L. Lemos, Jessica S. Ornelas, Vinícius Miranda, Daniel Nadas, Rafael Santana, Fabiano C. Watanabe, Kenji Taniguchi, Takashi van Troeye, Benoit Lamparski, Michael Meunier, Vincent Nguyen, Viet-Hung Paszko, Dawid Charlier, Jean-Christophe Campos, Leonardo C. Cançado, Luiz G. Medeiros-Ribeiro, Gilberto Jorio, Ado Physics Department Electrical Engineering Graduate Program Computer Science Department Universidade Federal de Minas Gerais Belo HorizonteMG31270-901 Brazil Physics Institute Universidade Federal da Bahia Campus Universitário de Ondina Salvador - BA40170-115 Brazil Divisão de Metrologia de Materiais Inmetro Duque de Caxias RJ25250-020 Brazil 1-2-1 Sengen Tsukuba-cityIbaraki305-0047 Japan Physics Applied Physics and Astronomy Jonsson Rowland Science Center Room 1C25 110 8th Street TroyNY12180 United States Louvain-la-Neuve Belgium

A low twist angle between the two stacked crystal networks in bilayer graphene enables self-organized lattice reconstruction with the formation of a periodic domain. This superlattice modulates the vibrational and electronic structures, imposing new rules for electron-phonon coupling and the eventual observation of strong correlation and superconductivity. Direct optical images of the crystal superlattice in reconstructed twisted bilayer graphene are reported here, generated by the inelastic scattering of light in a nano-Raman spectroscope. The observation of the crystallographic structure with visible light is made possible due to lattice dynamics localization, the images resembling spectral variations caused by the presence of strain solitons and topological points. The results are rationalized by a nearly-free-phonon model and electronic calculations that highlight the relevance of solitons and topological points, particularly pronounced for structures with small twist angles. We anticipate our discovery to play a role in understanding Jahn-Teller effects and electronic Cooper pairing, among many other important phonon-related effects, and it may be useful for characterizing devices in the most prominent platform for the field of *** Codes 82D03 Copyright © 2020, The Authors. All rights reserved.

关键词： Electronic structure

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Questions Classification in Online Discussion Towards Smart Learning Management System

Questions Classification in Online Discussion Towards Smart ...

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International Conference on Information Management and Technology (ICIMTech)

作者： Bambang Dwi Wijanarko Dina Fitria Murad Yaya Heryadi Lukas Hapnes Toba Widodo Budiharto Computer Science Department BINUS Online Learning Bina Nusantara University Jakarta Indonesia Information Systems Department BINUS Graduate Program Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Computer Science Department BINUS Graduate Program Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Faculty of Engineering Univeritas Katolik Indonesia Atma Jaya Cognitive Engineering Research Group (CERG) Jakarta Indonesia

The widespread interest toward online learning at higher education worldwide brings about necessity toward an smart Learning Management System (LMS), LMS with analytic functionalities, to increase learning outcome of the students. In an effort to develop a smart LMS which is able to both guiding students on learning process and giving automated feedback on online learning delivery to online learning management, this paper presents a preliminary and exploratory results toward textual documents from learning material repository and online discussion forum. The dataset for this study obtained from Bina Nusantara Online Learning repository. The study found interesting finding namely: there is a significant discrepancy between cognitive domain Taxonomy level between question raised in discussion forum and its respective level of learning outcomes. This findings were confirmed using Anova with P-value

关键词： Taxonomy computer science Discussion forums Medical services Support vector machines Machine learning Analysis of variance

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Patterns of somatic structural variation in human cancer genomes (vol 578, pg 112, 2020)

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NATURE 2023年第7948期614卷 E38-E38页

作者： Li, Yilong Roberts, Nicola D. Wala, Jeremiah A. Shapira, Ofer Schumacher, Steven E. Kumar, Kiran Khurana, Ekta Waszak, Sebastian Korbel, Jan O. Haber, James E. Imielinski, Marcin Weischenfeldt, Joachim Beroukhim, Rameen Campbell, Peter J. Cancer Genome Project Wellcome Trust Sanger Institute Hinxton UK Totient Inc Cambridge MA USA Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Department of Haematology University of Cambridge Cambridge UK Cambridge University Hospitals NHS Foundation Trust Cambridge UK Korea Advanced Institute of Science and Technology Daejeon South Korea Department of Zoology Genetics and Physical Anthropology University of Santiago de Compostela Santiago de Compostela Spain Centre for Research in Molecular Medicine and Chronic Diseases (CIMUS) University of Santiago de Compostela Santiago de Compostela Spain The Biomedical Research Centre (CINBIO) University of Vigo Vigo Spain Centre for Research in Molecular Medicine and Chronic Diseases (CiMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain Department of Zoology Genetics and Physical Anthropology (CiMUS) Universidade de Santiago de Compostela Santiago de Compostela Spain The Biomedical Research Centre (CINBIO) Universidade de Vigo Vigo Spain The Broad Institute of Harvard and MIT Cambridge MA USA Bioinformatics and Integrative Genomics Harvard University Cambridge MA USA Department of Cancer Biology Dana-Farber Cancer Institute Boston MA USA Broad Institute of MIT and Harvard Cambridge MA USA Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA Harvard Medical School Boston MA USA Massachusetts General Hospital Center for Cancer Research Charlestown MA USA Dana-Farber Cancer Institute Boston MA USA Department of Biostatistics and Computational Biology Dana-Farber Cancer Institute and Harvard Medical School Boston MA USA Weill Cornell Medical College New York NY USA Department of Physiology and Biophysics Weill Cornell Medicine New York NY USA Institute for Computational Biomedicine Weill Cornell Medicine New York NY USA Controlled Department and Institution New York NY USA Englander Institute for Precision Medicine Weill Cornell Medicine Ne

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The evolutionary history of 2,658 cancers (vol 578, pg 122, 2020)

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NATURE 2023年第7948期614卷 E42-E42页

作者： Gerstung, Moritz Jolly, Clemency Leshchiner, Ignaty Dentro, Stefan C. Gonzalez, Santiago Rosebrock, Daniel Mitchell, Thomas J. Rubanova, Yulia Anur, Pavana Yu, Kaixian Tarabichi, Maxime Deshwar, Amit Wintersinger, Jeff Kleinheinz, Kortine Vazquez-Garcia, Ignacio Haase, Kerstin Jerman, Lara Sengupta, Subhajit Macintyre, Geoff Malikic, Salem Donmez, Nilgun Livitz, Dimitri G. Cmero, Marek Demeulemeester, Jonas Schumacher, Steven Fan, Yu Yao, Xiaotong Lee, Juhee Schlesner, Matthias Boutros, Paul C. Bowtell, David D. Zhu, Hongtu Getz, Gad Imielinski, Marcin Beroukhim, Rameen Sahinalp, S. Cenk Ji, Yuan Peifer, Martin Markowetz, Florian Mustonen, Ville Yuan, Ke Wang, Wenyi Morris, Quaid D. Spellman, Paul T. Wedge, David C. Van Loo, Peter European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Cambridge UK European Molecular Biology Laboratory Genome Biology Unit Heidelberg Germany Wellcome Sanger Institute Cambridge UK Genome Biology Unit European Molecular Biology Laboratory (EMBL) Heidelberg Germany University of Ljubljana Ljubljana Slovenia The Francis Crick Institute London UK Big Data Institute University of Oxford Oxford UK Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Big Data Institute Li Ka Shing Centre University of Oxford Oxford UK University of Cambridge Cambridge UK Cambridge University Hospitals NHS Foundation Trust Cambridge UK Department of Applied Mathematics and Theoretical Physics Centre for Mathematical Sciences University of Cambridge Cambridge UK Department of Epidemiology and Biostatistics Memorial Sloan Kettering Cancer Center New York NY USA Department of Statistics Columbia University New York NY USA Department of Haematology University of Cambridge Cambridge UK University of Leuven Leuven Belgium Broad Institute of MIT and Harvard Cambridge MA USA Center for Cancer Research Massachusetts General Hospital Charlestown MA USA Department of Pathology Massachusetts General Hospital Boston MA USA Harvard Medical School Boston MA USA Center for Cancer Research Massachusetts General Hospital Boston MA USA Dana-Farber Cancer Institute Boston MA USA Department of Medical Oncology Dana-Farber Cancer Institute Boston MA USA Department of Cancer Biology Dana-Farber Cancer Institute Boston MA USA Oxford NIHR Biomedical Research Centre Oxford UK Oxford NIHR Biomedical Research Centre University of Oxford Oxford UK University of Toronto Toronto Ontario Canada Vector Institute Toronto Ontario Canada Vector Institute Toronto ON Canada Department of Computer Science University of Toronto Toronto ON Canada Ontario Institute for Cancer Research Toronto Ontario Canada University of California Los Angeles

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The repertoire of mutational signatures in human cancer (vol 578, pg 94, 2020)

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NATURE 2023年第7948期614卷 E41-E41页

作者： Alexandrov, Ludmil B. Kim, Jaegil Haradhvala, Nicholas J. Huang, Mi Ni Ng, Alvin Wei Tian Wu, Yang Boot, Arnoud Covington, Kyle R. Gordenin, Dmitry A. Bergstrom, Erik N. Islam, S. M. Ashiqul Lopez-Bigas, Nuria Klimczak, Leszek J. McPherson, John R. Morganella, Sandro Sabarinathan, Radhakrishnan Wheeler, David A. Mustonen, Ville Getz, Gad Rozen, Steven G. Stratton, Michael R. Department of Cellular and Molecular Medicine Department of Bioengineering Moores Cancer Center University of California San Diego CA USA Wellcome Sanger Institute Wellcome Genome Campus Hinxton UK Department of Cellular and Molecular Medicine and Department of Bioengineering University of California San Diego La Jolla CA USA UC San Diego Moores Cancer Center San Diego CA USA University of California San Diego San Diego CA USA Broad Institute of MIT and Harvard Cambridge MA USA Center for Cancer Research Massachusetts General Hospital Boston MA USA Massachusetts General Hospital Boston MA USA Department of Pathology Massachusetts General Hospital Boston MA USA Harvard Medical School Boston MA USA Laboratory for Medical Science Mathematics RIKEN Center for Integrative Medical Sciences Yokohama Japan Computational Biology Program Ontario Institute for Cancer Research Toronto ON Canada Programme in Cancer & Stem Cell Biology Duke-NUS Medical School Singapore Singapore Centre for Computational Biology Duke-NUS Medical School Singapore Singapore Programme in Cancer and Stem Cell Biology Duke-NUS Medical School Singapore Singapore Programme in Cancer and Stem Cell Biology Centre for Computational Biology Duke-NUS Medical School Singapore Singapore SingHealth Duke-NUS Institute of Precision Medicine National Heart Centre Singapore Singapore Singapore Cancer Science Institute of Singapore National University of Singapore Singapore Singapore Institute of Molecular and Cell Biology Singapore Singapore Laboratory of Cancer Epigenome Division of Medical Science National Cancer Centre Singapore Singapore Singapore Duke-NUS Medical School Singapore Singapore Human Genome Sequencing Center Baylor College of Medicine Houston TX USA Dan L. Duncan Cancer Center Baylor College of Medicine Houston TX USA Department of Molecular and Human Genetics Baylor College of Medicine Houston TX USA Genome Integrity and Structural Biology Laboratory National Ins

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Erratum to: Search for exclusive Higgs and Z boson decays to ϕγ and ργ with the ATLAS detector

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Journal of High Energy Physics 2023年第12期2023卷 1-21页

作者： Aaboud, M. Aad, G. Abbott, B. Abdinov, O. Abeloos, B. Abidi, S. H. AbouZeid, O. S. Abraham, N. L. Abramowicz, H. Abreu, H. Abreu, R. Abulaiti, Y. Acharya, B. S. Adachi, S. Adamczyk, L. Adelman, J. Adersberger, M. Adye, T. Affolder, A. A. Afik, Y. Agatonovic-Jovin, T. Agheorghiesei, C. Aguilar-Saavedra, J. A. Ahlen, S. P. Ahmadov, F. Aielli, G. Akatsuka, S. Akerstedt, H. Åkesson, T. P. A. Akilli, E. Akimov, A. V. Alberghi, G. L. Albert, J. Albicocco, P. Alconada Verzini, M. J. Alderweireldt, S. C. Aleksa, M. Aleksandrov, I. N. Alexa, C. Alexander, G. Alexopoulos, T. Alhroob, M. Ali, B. Aliev, M. Alimonti, G. Alison, J. Alkire, S. P. Allbrooke, B. M. M. Allen, B. W. Allport, P. P. Aloisio, A. Alonso, A. Alonso, F. Alpigiani, C. Alshehri, A. A. Alstaty, M. I. Alvarez Gonzalez, B. Álvarez Piqueras, D. Alviggi, M. G. Amadio, B. T. Amaral Coutinho, Y. Amelung, C. Amidei, D. Amor Dos Santos, S. P. Amoroso, S. Amundsen, G. Anastopoulos, C. Ancu, L. S. Andari, N. Andeen, T. Anders, C. F. Anders, J. K. Anderson, K. J. Andreazza, A. Andrei, V. Angelidakis, S. Angelozzi, I. Angerami, A. Anisenkov, A. V. Anjos, N. Annovi, A. Antel, C. Antonelli, M. Antonov, A. Antrim, D. J. Anulli, F. Aoki, M. Aperio Bella, L. Arabidze, G. Arai, Y. Araque, J. P. Araujo Ferraz, V. Arce, A. T. H. Ardell, R. E. Arduh, F. A. Arguin, J-F. Argyropoulos, S. Arik, M. Armbruster, A. J. Armitage, L. J. Arnaez, O. Arnold, H. Arratia, M. Arslan, O. Artamonov, A. Artoni, G. Artz, S. Asai, S. Asbah, N. Ashkenazi, A. Asquith, L. Assamagan, K. Astalos, R. Atkinson, M. Atlay, N. B. Augsten, K. Avolio, G. Axen, B. Ayoub, M. K. Azuelos, G. Baas, A. E. Baca, M. J. Bachacou, H. Bachas, K. Backes, M. Bagnaia, P. Bahmani, M. Bahrasemani, H. Baines, J. T. Bajic, M. Baker, O. K. Bakker, P. J. Baldin, E. M. Balek, P. Balli, F. Balunas, W. K. Banas, E. Bandyopadhyay, A. Banerjee, Sw. Bannoura, A. A. E. Barak, L. Barberio, E. L. Barberis, D. Barbero, M. Barillari, T. Barisits, M.-S. Barkeloo, J. T. Barklow, T. Barlow, N. Barnes, S. L. Barnett, B. M. Barnett, R. M. Barno Faculté des Sciences Université Mohamed Premier and LPTPM Oujda Morocco CPPM Aix-Marseille Université and CNRS/IN2P3 Marseille France Homer L. Dodge Department of Physics and Astronomy University of Oklahoma Norman United States of America Institute of Physics Azerbaijan Academy of Sciences Baku Azerbaijan LAL Univ. Paris-Sud CNRS/IN2P3 Université Paris-Saclay Orsay France Department of Physics University of Toronto Toronto Canada Santa Cruz Institute for Particle Physics University of California Santa Cruz Santa Cruz United States of America Department of Physics and Astronomy University of Sussex Brighton United Kingdom Raymond and Beverly Sackler School of Physics and Astronomy Tel Aviv University Tel Aviv Israel Department of Physics Technion: Israel Institute of Technology Haifa Israel Center for High Energy Physics University of Oregon Eugene United States of America Department of Physics Stockholm University Stockholm Sweden The Oskar Klein Centre Stockholm Sweden INFN Gruppo Collegato di Udine Sezione di Trieste Udine Italy ICTP Trieste Italy Department of Physics King’s College London London United Kingdom International Center for Elementary Particle Physics and Department of Physics The University of Tokyo Tokyo Japan AGH University of Science and Technology Faculty of Physics and Applied Computer Science Krakow Poland Department of Physics Northern Illinois University DeKalb United States of America Fakultät für Physik Ludwig-Maximilians-Universität München München Germany Particle Physics Department Rutherford Appleton Laboratory Didcot United Kingdom Institute of Physics University of Belgrade Belgrade Serbia Department of Physics Alexandru Ioan Cuza University of Iasi Iasi Romania Laboratório de Instrumentação e Física Experimental de Partículas – LIP Lisboa Portugal Departamento de Fisica Teorica y del Cosmos Universidad de Granada Granada Portugal Department of Physics Boston University Boston United States of America Joi

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The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2

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Cell 2025年第12期188卷 3167-3183.e18页

作者： Pekar, Jonathan E. Lytras, Spyros Ghafari, Mahan Magee, Andrew F. Parker, Edyth Wang, Yu Ji, Xiang Havens, Jennifer L. Katzourakis, Aris Vasylyeva, Tetyana I. Suchard, Marc A. Hughes, Alice C. Hughes, Joseph Rambaut, Andrew Robertson, David L. Dellicour, Simon Worobey, Michael Wertheim, Joel O. Lemey, Philippe Institute of Ecology and Evolution University of Edinburgh Edinburgh United Kingdom Bioinformatics and Systems Biology Graduate Program University of California San Diego La Jolla 92093 CA United States Department of Biomedical Informatics University of California San Diego La Jolla 92093 CA United States Department of Medicine University of California San Diego La Jolla 92093 CA United States Division of Systems Virology Department of Microbiology and Immunology The Institute of Medical Science The University of Tokyo Tokyo Japan Medical Research Council University of Glasgow Centre for Virus Research Glasgow United Kingdom Department of Biology University of Oxford Oxford United Kingdom Department of Human Genetics David Geffen School of Medicine University of California Los Angeles Los Angeles 90095 CA United States Department of Immunology and Microbiology The Scripps Research Institute La Jolla 92037 CA United States Institute of Genomics and Global Health Redeemer's University Osun State Ede Nigeria Department of Computer Science and Engineering University of California San Diego La Jolla 92093 CA United States Department of Mathematics School of Science and Engineering Tulane University New Orleans LA United States Department of Population Health and Disease Prevention University of California Irvine Irvine 92617 CA United States Department of Biostatistics Fielding School of Public Health University of California Los Angeles Los Angeles 90095 CA United States Department of Computational Medicine David Geffen School of Medicine University of California Los Angeles Los Angeles 90095 CA United States School of Biological Sciences University of Hong Kong Hong Kong Hong Kong China Biodiversity Green Development Foundation Beijing China Spatial Epidemiology Lab (SpELL) Université Libre de Bruxelles CP160/12 50 av. FD Roosevelt Bruxelles 1050 Belgium Department of Microbiology Immunology and Transplantation Rega Institute

The emergence of SARS-CoV in 2002 and SARS-CoV-2 in 2019 led to increased sampling of sarbecoviruses circulating in horseshoe bats. Employing phylogenetic inference while accounting for recombination of bat sarbecoviruses, we find that the closest-inferred bat virus ancestors of SARS-CoV and SARS-CoV-2 existed less than a decade prior to their emergence in humans. Phylogeographic analyses show bat sarbecoviruses traveled at rates approximating their horseshoe bat hosts and circulated in Asia for millennia. We find that the direct ancestors of SARS-CoV and SARS-CoV-2 are unlikely to have reached their respective sites of emergence via dispersal in the bat reservoir alone, supporting interactions with intermediate hosts through wildlife trade playing a role in zoonotic spillover. These results can guide future sampling efforts and demonstrate that viral genomic regions extremely closely related to SARS-CoV and SARS-CoV-2 were circulating in horseshoe bats, confirming their importance as the reservoir species for SARS viruses. © 2025 The Authors

关键词： molecular epidemiology phylogeography sarbecoviruses virus evolution

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Genomic basis for RNA alterations in cancer (vol 578, pg 129, 2020)

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NATURE 2023年第7948期614卷 E37-E37页

作者： Calabrese, Claudia Davidson, Natalie R. Demircioglu, Deniz Fonseca, Nuno A. He, Yao Lehmann, Kjong-Van Liu, Fenglin Shiraishi, Yuichi Soulette, Cameron M. Urban, Lara Greger, Liliana Li, Siliang Liu, Dongbing Perry, Marc D. Xiang, Qian Zhang, Fan Zhang, Junjun Bailey, Peter Erkek, Serap Hoadley, Katherine A. Hou, Yong Huska, Matthew R. Kilpinen, Helena Korbel, Jan O. Marin, Maximillian G. Markowski, Julia Nandi, Tannistha Pan-Hammarstrom, Qiang Pedamallu, Chandra Sekhar Siebert, Reiner Stark, Stefan G. Su, Hong Tan, Patrick Waszak, Sebastian M. Yung, Christina Zhu, Shida Awadalla, Philip Creighton, Chad J. Meyerson, Matthew Ouellette, B. F. Francis Wu, Kui Yang, Huanming Brazma, Alvis Brooks, Angela N. Goke, Jonathan Ratsch, Gunnar Schwarz, Roland F. Stegle, Oliver Zhang, Zemin European Molecular Biology Laboratory European Bioinformatics Institute Hinxton UK European Molecular Biology Laboratory European Bioinformatics Institute (EMBL-EBI) Cambridge UK Genome Biology Unit European Molecular Biology Laboratory (EMBL) Heidelberg Germany CIBIO/InBIO - Research Center in Biodiversity and Genetic Resources Universidade do Porto Vairão Portugal Berlin Institute for Medical Systems Biology Max Delbruck Center for Molecular Medicine Berlin Germany German Cancer Consortium (DKTK) partner site Berlin Germany German Cancer Research Center (DKFZ) Heidelberg Germany Berlin Institute for Medical Systems Biology Max Delbrück Center for Molecular Medicine Berlin Germany German Cancer Consortium (DKTK) Partner site Berlin Berlin Germany European Molecular Biology Laboratory Genome Biology Unit Heidelberg Germany Division of Computational Genomics and Systems Genetics German Cancer Research Center (DKFZ) Heidelberg Germany ETH Zurich Zurich Switzerland Memorial Sloan Kettering Cancer Center New York NY USA Weill Cornell Medical College New York NY USA SIB Swiss Institute of Bioinformatics Lausanne Switzerland University Hospital Zurich Zurich Switzerland Computational Biology Center Memorial Sloan Kettering Cancer Center New York NY USA Department of Biology ETH Zurich Zürich Switzerland Department of Computer Science ETH Zurich Zurich Switzerland Korea University Seoul South Korea Computational and Systems Biology Program Memorial Sloan Kettering Cancer Center New York NY USA Department of Physiology and Biophysics Weill Cornell Medicine New York NY USA Institute for Computational Biomedicine Weill Cornell Medicine New York NY USA Controlled Department and Institution New York NY USA Englander Institute for Precision Medicine Weill Cornell Medicine New York NY USA National University of Singapore Singapore Singapore Genome Institute of Singapore Singapore Singapore Computational and Systems Biology Genome Institute of Singap

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A Whole Crow Search Algorithm for Solving Data Clustering

A Whole Crow Search Algorithm for Solving Data Clustering

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International Conference on Technologies and Applications of Artificial Intelligence (TAAI)

作者： Ze-Xue Wu Ko-Wei Huang Abba Suganda Girsang Department of Electrical Engineering National Kaohsiung University of Science and Technology Kaohsiung City Taiwan R.O.C Computer Science Department BINUS Graduate Program-Master of Computer Science Bina Nusantara University Jakarta Indonesia

Data clustering is a well-known data mining approach that usually used to minimizes the intra distance but maximizes inter distance of each data center. The cluster problem has been proved to be an NP-hard problem. In this paper, a hybrid algorithm based on Whole optimization algorithm (WOA) and Crow search algorithm (CSA) is proposed, namely HWCA. The HWCA algorithm has the advantages of the search strategy of the WOA and CSA. In addition to, there are two operators used to improve the quality of solution, namely hybrid individual operator and enhance diversity operator. The hybrid individual operator is used to exchanges individuals from the WOA and CSA systems by using the roulette wheel approach. In other hand, the HWCA performs enhance diversity operator to improve the quality of each system. More over, the HWCA is incorporated with center optimization strategy to enhance diversity of each system. In the performance evaluation, the proposed MPGO algorithm was comparison WOA and CSA algorithm with six well-known UCI benchmarks. The results show that the proposed algorithm has a higher measure of accuracy rate with comparison algorithms.

关键词： Clustering algorithms Optimization Whales Search problems Wheels Benchmark testing Random variables

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