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检索条件"机构=Department of Translational Data Science and Informatics"
189 条 记 录,以下是1-10 订阅
排序:
A Large-scale Multimodal Study for Predicting Mortality Risk Using Minimal and Low Parameter Models and Separable Risk Assessment
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IEEE Journal of Biomedical and Health informatics 2025年 第5期29卷 3762-3771页
作者: Cerna, Alvaro E. Ulloa vanMaanen, David P. Jing, Linyuan Stough, Joshua V. Patel, Aalpen A. Haggerty, Christopher M. Fornwalt, Brandon K. Pattichis, Marios S. Department of Translational Data Science and Informatics Geisinger PA17822 United States University of New Mexico Department of Electrical and Computer Engineering NM87131 United States
The majority of biomedical studies use limited datasets that may not generalize over large heterogeneous datasets that have been collected over several decades. The current paper develops and validates several multimo... 详细信息
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Psoriasis: Perspectives from Irwin M. Braverman, MD
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Clinics in Dermatology 2025年 第2期43卷 166-169页
作者: Cohen, Jeffrey M. Bunick, Christopher G. Department of Dermatology Yale School of Medicine New Haven CT United States Department of Biomedical Informatics and Data Science Yale School of Medicine New Haven CT United States Program in Translational Biomedicine Yale University New Haven CT United States
Dr Irwin M. Braverman is recognized as an expert on many skin diseases, including psoriasis, an immune-mediated disorder that presents with scaly erythematous plaques. The most common clinical subtype is plaque psoria... 详细信息
来源: 评论
FEDERATED INVERSE PROBABILITY TREATMENT WEIGHTING FOR INDIVIDUAL TREATMENT EFFECT ESTIMATION
arXiv
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arXiv 2025年
作者: Yin, Changchang Chen, Hong-You Chao, Wei-Lun Zhang, Ping Department of Computer Science and Engineering The Ohio State University ColumbusOH United States Department of Computer Science and Engineering Department of Biomedical Informatics Translational Data Analytics Institute The Ohio State University ColumbusOH United States
Individual treatment effect (ITE) estimation is to evaluate the causal effects of treatment strategies on some important outcomes, which is a crucial problem in healthcare. Most existing ITE estimation methods are des... 详细信息
来源: 评论
LIDDIA: Language-based Intelligent Drug Discovery Agent
arXiv
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arXiv 2025年
作者: Averly, Reza Baker, Frazier N. Ning, Xia Department of Computer Science and Engineering The Ohio State University United States Department of Biomedical Informatics The Ohio State University United States Translational Data Analytics Institute The Ohio State University United States College of Pharmacy The Ohio State University United States
Drug discovery is a long, expensive, and complex process, relying heavily on human medicinal chemists, who can spend years searching the vast space of potential therapies. Recent advances in artificial intelligence fo... 详细信息
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GeLLM3O: Generalizing Large Language Models for Multi-property Molecule Optimization
arXiv
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arXiv 2025年
作者: Dey, Vishal Hu, Xiao Ning, Xia Department of Computer Science and Engineering The Ohio State University United States Translational Data Analytics Institute The Ohio State University United States Department of Biomedical Informatics The Ohio State University United States College of Pharmacy The Ohio State University United States
Despite recent advancements, most computational methods for molecule optimization are constrained to single- or double-property optimization tasks and suffer from poor scalability and generalizability to novel optimiz...
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Single-cell technologies: current and near future
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science China(Life sciences) 2025年 第1期68卷 1-4页
作者: Chenfei Wang Qi Liu Xiaohui Fan Tieliu Shi KeyLaboratory of Spine and Spinal CordInjury Repairand Regeneration Ministry of EducationOrthopedics DepartmentTongji HospitalBioinformatics DepartmentSchoolofLifeSciencesandTechnologyTongji UniversityShanghai 200082China Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji UniversityShanghai 200092China Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji UniversityShanghai 200082China Research Institute of Intelligent Computing Zhejiang LabHangzhou 311121China Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang UniversityJiaxing 314103China Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal UniversityShanghai 200241China Key Laboratory of Advanced Theory and Application in Statistics and Data Science(MOE) School of StatisticsEast China Normal UniversityShanghai 200062China
Single-cell technologies enable the indepth exploration of multiple biological hierarchies at the scale of individual cells,which have deepened our knowledge of cellular diversity,tissue organization,and overall organ... 详细信息
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Translation dysregulation in cancer as a source for targetable antigens
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Cancer Cell 2025年 第5期43卷 823-840.e18,20页
作者: Weller, Chen Bartok, Osnat McGinnis, Christopher S. Palashati, Heyilimu Chang, Tian-Gen Malko, Dmitry Shmueli, Merav D. Nagao, Asuteka Hayoun, Deborah Murayama, Ayaka Sakaguchi, Yuriko Poulis, Panagiotis Khatib, Aseel Erlanger Avigdor, Bracha Gordon, Sagi Cohen Shvefel, Sapir Zemanek, Marie J. Nielsen, Morten M. Boura-Halfon, Sigalit Sagie, Shira Gumpert, Nofar Yang, Weiwen Alexeev, Dmitry Kyriakidou, Pelgia Yao, Winnie Zerbib, Mirie Greenberg, Polina Benedek, Gil Litchfield, Kevin Petrovich-Kopitman, Ekaterina Nagler, Adi Oren, Roni Ben-Dor, Shifra Levin, Yishai Pilpel, Yitzhak Rodnina, Marina Cox, Jürgen Merbl, Yifat Satpathy, Ansuman T. Carmi, Yaron Erhard, Florian Suzuki, Tsutomu Buskirk, Allen R. Olweus, Johanna Ruppin, Eytan Schlosser, Andreas Samuels, Yardena Department of Molecular Cell Biology Weizmann Institute of Science Rehovot 7610001 Israel Department of Pathology Stanford University Stanford 94305 CA United States Parker Institute for Cancer Immunotherapy San Francisco 94129 CA United States Department of Cancer Immunology Institute for Cancer Research Oslo University Hospital Oslo 0379 Norway Precision Immunotherapy Alliance University of Oslo Oslo Norway Cancer Data Science Laboratory Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda 20892 MD United States Department of Systems Immunology Weizmann Institute of Science Rehovot 7610001 Israel Department of Chemistry and Biotechnology of Engineering The University of Tokyo Tokyo 113-8656 Japan Department of Physical Biochemistry Max Planck Institute for Multidisciplinary Sciences Göttingen 37077 Germany Department of Pathology Sackler School of Medicine Tel Aviv University Tel Aviv 69978 Israel Department of Immunology and Regenerative Biology Weizmann Institute of Science Rehovot 7610001 Israel Computational Systems Biochemistry Research Group Max-Planck Institute of Biochemistry Martinsried 82152 Germany Department of Veterinary Resources Weizmann Institute of Science Rehovot 7610001 Israel Tissue Typing and Immunogenetics Unit Hadassah Hebrew University Hospital Jerusalem 9112102 Israel CRUK Lung Cancer Centre of Excellence University College London Cancer Institute London WC1E 6DD United Kingdom Tumour Immunogenomics and Immunosurveillance Laboratory University College London Cancer Institute London WC1E 6DD United Kingdom Department of Life Science Core Facilities Weizmann Institute of Science Rehovot 7610001 Israel Bioinformatics Unit Department of Life Sciences Core Facilities Weizmann Institute of Science Rehovot 7610001 Israel de Botton Institute for Protein Profiling the Nancy and Stephen Grand Israel National Center for Personalized Medicine Weizmann Institute of Science Rehovot
Aberrant peptides presented by major histocompatibility complex (MHC) molecules are targets for tumor eradication, as these peptides can be recognized as foreign by T cells. Protein synthesis in malignant cells is dys... 详细信息
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T2 Coach: A Qualitative Study of an Automated Health Coach for Diabetes Self-Management  25
T2 Coach: A Qualitative Study of an Automated Health Coach f...
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Proceedings of the 2025 CHI Conference on Human Factors in Computing Systems
作者: Elliot G Mitchell Pooja Desai Arlene Smaldone Andrea Cassells, MPH Jonathan N. Tobin, PhD David Albers Matthew Levine Lena Mamykina Geisinger Health Danville Pennsylvania USA Department of Biomedical Informatics Columbia University Irving Medical Center New York New York USA School of Nursing Columbia University New York New York USA College of Dental Medicine Columbia University New York New York USA Clinical Directors Network New York New York USA Clinical Directors Network (CDN) New York New York USA Center for Clinical and Translational Science The Rockefeller University New York New York USA Department of Pediatrics Section of Informatics and Data Science University of Colorado Anschutz Medical Center Aurora Colorado USA Eric and Wendy Schmidt Center Broad Institute of MIT and Harvard Cambridge Massachusetts USA Department of Biomedical Informatics Columbia University New York New York USA
Computational intelligence is increasingly common in interactive systems in many domains, including health. Health coaching with conversational agents (CA) can reach wide populations, but the level of computational in... 详细信息
来源: 评论
Planning with Diffusion Models for Target-Oriented Dialogue Systems
arXiv
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arXiv 2025年
作者: Du, Hanwen Peng, Bo Ning, Xia Department of Computer Science and Engineering The Ohio State University United States Department of Biomedical Informatics The Ohio State University United States Translational Data Analytics Institute The Ohio State University United States
Target-Oriented Dialogue (TOD) remains a significant challenge in the LLM era, where strategic dialogue planning is crucial for directing conversations toward specific targets. However, existing dialogue planning meth...
来源: 评论
Using a statewide health information exchange to Enhance COVID research and Surveillance: The impact of information fragmentation
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International Journal of Medical informatics 2025年
作者: Katie S. Allen Seho Park John Price Xia Ning Titus Schleyer Center for Biomedical Informatics Regenstrief Institute Inc United States Department of Industrial and Data Engineering Hongik University South Korea Biomedical Informatics Computer Science and Engineering Translational Data Analytics Institute The Ohio State University United States School of Medicine Indiana University United States
Objective Use of electronic health data for public health surveillance and research has become almost ubiquitous. However, since many patients routinely receive care from multiple healthcare systems, not all informati...
来源: 评论