Neurodegenerative diseases (NDGs) can slowly damage the brain as well as the central and peripheral nervous systems. Parkinson's disease (PD) is a sensitive sensory disease that causes a malfunction of dynamic equ...
详细信息
Neurodegenerative diseases (NDGs) can slowly damage the brain as well as the central and peripheral nervous systems. Parkinson's disease (PD) is a sensitive sensory disease that causes a malfunction of dynamic equilibrium. PD causes certain brain neuronal cells to gradually split or die. There are certain significant characteristics of PD that may increase the risk of acquiring deferent NDGs including Alzheimer's disease (AD), Amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), and Multiple sclerosis disease (MSL). We conducted a transcriptomic analysis to find connections between PD and NDGs. To explore how PD may affect the advancement of NDGs, we employed a quantitative framework to analyze the gene expression microarray dataset. To obtain genomic associations between PD and NDGs, we performed gene expression profiling by identifying dysregulated pathways, gene ontologies, PPIs, and phylogenetic analysis. We found 15, 11, 28, and 24 significant genes are shared between PD and AD, ALS, HD, and MSL respectively. We also identified a significant number of functional and ontological pathways, hub proteins and phylogenetic associations that indicate PD may have a link to develop NDGs (AD, ALS, HD, and MSL). We validate our findings through gold benchmark databases. This systematic approach is highly beneficial in understanding the causes and progression of NDGs owing to the effect of PD.
A comprehensive visual traits-based recommendation system is designed for proactive retailing in a physical store environment. The proposed system utilizes computer vision algorithms to analyze various visual traits o...
详细信息
When identifying facial expressions using a set of salient features, reversible neural network plays a crucial role. In order to create a prominent feature set, these salient features are extracted from a face image u...
详细信息
The Internet of Medical Things (IoMT) revolutionizes healthcare by integrating medical devices and systems with the internet. However, the vast amounts of sensitive medical data in IoMT networks pose significant secur...
详细信息
We consider the following question of bounded simultaneous messages (BSM) protocols: Can computationally unbounded Alice and Bob evaluate a function f(x, y) of their inputs by sending polynomial-size messages to a com...
详细信息
In recent days, DeFi tokens have gained popularity as an investment option in the pandemic period and has gained a significant amount of investment. Cryptocurrency trading is a type of DeFi that has gained a lot of at...
详细信息
This study compares various machine learning techniques such as logistic regression, support vector machine (SVM), random forest, Naïve Bayes, and decision tree. Later, a feature selection approach that considers...
This study compares various machine learning techniques such as logistic regression, support vector machine (SVM), random forest, Naïve Bayes, and decision tree. Later, a feature selection approach that considers the Univariate Feature Selection (UFS) method was applied to select the best features based on statistical testing. In this research, we employed the ANOVA F-test to pick the most significant features, and we used a cutting-edge dataset for experimental analysis. The ANOVA F-test was used to exploit the target variable's dependency on the continuous variables. The results show that employing the UFS approach for picking features improves the performance of the algorithms. According to the experimental results, using UFS with the logistic regression technique yields 93.3% accuracy, whereas the standalone Naïve Bayes algorithm achieved the best accuracy.
Hyperledger Fabric is a scalable and modular consortium blockchain platform designed for enterprise applications, where cryptographic algorithms play a fundamental role in ensuring data security and integrity. However...
详细信息
ISBN:
(数字)9789526524634
ISBN:
(纸本)9798331595425
Hyperledger Fabric is a scalable and modular consortium blockchain platform designed for enterprise applications, where cryptographic algorithms play a fundamental role in ensuring data security and integrity. However, the native Fabric framework lacks support for national cryptographic standards, necessitating the integration of secure cryptographic mechanisms. This study proposes an enhanced approach to embedding national cryptographic algorithms into the Fabric platform. First, Graph-based Dependency Analysis is employed to investigate the interaction logic among Fabric components and the invocation of cryptographic functions, facilitating an efficient integration strategy. Next, the Lightweight Post-Quantum Cryptography (L-PQC) framework, which enhances resistance to quantum threats while maintaining computational efficiency, is utilized to integrate SM2, SM3, and SM4 cryptographic algorithms into Fabric’s Blockchain Cryptographic Service Provider (BCCSP) module. Subsequently, a Microservices-Based Cryptography Integration mechanism is designed to establish seamless mapping between Fabric’s cryptographic function calls and the national cryptographic algorithm interfaces, ensuring compatibility and interoperability. Finally, the implementation is evaluated using Blockchain Simulation Environments, where a fabric-gm consortium blockchain instance is deployed to validate the correctness and efficiency of the embedded cryptographic modules. Comparative analysis with the original Fabric platform reveals that the enhanced system introduces a 2.5% increase in network startup time, a 1.8× rise in transaction latency, and a 7.5% increase in dynamic certificate generation time, while maintaining operational performance within acceptable limits. The proposed integration strategy ensures secure and efficient cryptographic support within Hyperledger Fabric, making it resilient to emerging cryptographic threats.
Haptic simulation systems use the sensation of touch to allow users to experience virtual surroundings. In interfaces that are based on impedance, haptics controllers are sampled data that use angular position and vel...
详细信息
In the pursuit of sustainable living and enhanced user comfort, the integration of smart technologies into everyday devices has become paramount. This paper highlights the importance of dynamic lighting control in imp...
详细信息
ISBN:
(数字)9798350353778
ISBN:
(纸本)9798350353785
In the pursuit of sustainable living and enhanced user comfort, the integration of smart technologies into everyday devices has become paramount. This paper highlights the importance of dynamic lighting control in improving energy efficiency and the overall quality of life. Traditional lighting systems often fail to account for the dynamic nature of human activities, resulting in unnecessary energy wastage and suboptimal lighting conditions. The proposed system seeks to bridge the gap between existing lighting systems and the evolving needs of modern indoor spaces, with its focus on adaptability, efficiency, and user-centricity, promoting a more comfortable and nurturing environment. Although earlier studies have explored various aspects of smart lighting technologies, there remains a paucity of comprehensive solutions that integrate machine learning with sensor technologies to create truly adaptive environments. Novel algorithms have been utilized to optimize both visual comfort and energy efficiency. This system achieves up to 45-70% energy savings compared to existing lighting systems, making it a promising solution for both environmental and economic concerns.
暂无评论