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Proceedings of the IEEE Computational Systems Bioinformatics Conference, CSB

作者： Fang-Xiang Wu A.J. Kusalik Wen-Jun Zhang Department of Biomedical Engineering University of Saskatchewan Saskatoon SAS Canada Department of Computer Science University of Saskatchewan Saskatoon SAS Canada University of Saskatchewan Saskatoon SK CA Dept. of Biomedical Eng. Saskatchewan Univ. Saskatoon Sask. Canada

Recently we proposed a state-space model with time delays for gene regulatory networks. Although the system can be uniquely determined under some assumptions, the solution space is still too large to use an exhaustive search method to find the optimal solution. This work employs Boolean variables to capture the existence of the discrete time delays of the regulatory relationships among the internal variables, and proposes a genetic algorithm (GA) to determine the optimal Boolean variables (the optimal solution) and to further infer gene regulatory networks with time delays. Computational experiments performed on a real gene expression dataset show that GA is effective at finding the optimal solution. Not only does the regulatory network with time delay obtained from the dataset possesses the expected properties of a real one, but the approach also improves the prediction accuracy by 72%, compared to gene regulatory network without time delays.

关键词： Genetic algorithms Delay effects Intelligent networks Gene expression Search methods Equations Parameter estimation Accuracy Bayesian methods Information analysis

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Image attachment using fuzzy-genetic algorithms

Image attachment using fuzzy-genetic algorithms

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2004 IEEE International Conference on Fuzzy Systems - Proceedings

作者： Reskó, Barna Korondi, Péter Petres, Zoltán Bourges, Jean François Hashimoto, Hideki Fac. Elec. Eng. and Informatics Budapest Univ. Technol. and Econ. Tokyo Japan Computer Science Engineering Dept. Lavai University Ste-Foy PQ G1K 7P4 Canada Institute of Industrial Sciences University of Tokyo Intgd. Intelligent S. Japanese-H.L. Tokyo Japan

ISBN: (纸本)0780383532

This paper gives contribution to the construction of an image mosaic by pasting together a sequence of photographs taken by a regular digital camera from the same position but in different directions. In order to find the best match between two overlapping images, a fuzzy-genetic based algorithm is presented. A translation vector with a minimal difference between the common picture parts has to be found. The difference is defined using the fuzzyfied contours of each images. The search of the optimal translation is considered as a minimization process. This paper proposes a method that uses genetic algorithms to find the minimum point corresponding to the optimal translation. Using the fuzzy based comparison of the two images yields a fast fitness function, while the implementation of the proposed method in a genetic hardware has a low and variable computational cost. The precision of the method is inverse-proportional with the computational time, which makes it ideal to be used in real time systems.

关键词： Image processing

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k-means nearest neighbor classifier for voice pathology

k-means nearest neighbor classifier for voice pathology

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IEEE India Conference (INDICON)

作者： T. Ananthakrishna K. Shama U.C. Niranjan Dept. of Studies in Computer Science MTech. CCT-IV semester University of Mysore Manasagangotri Mysore Karnataka Dept. of Electronics and commn. Engg. Manipal Institute of Technology Manipal Karnataka India Department of E & C and Biomedical Engg Manipal Institute of Technology Manipal Karnataka India

The noninvasive acoustical analysis of normal and pathological voices help speech specialists to perform accurate diagnose of diseases. Pathological voices show higher vocal noise level due to malfunctioning of vocal cords. Addition of noise component in speech has found to change the spectral properties. In this study, we show the use of energy spectrum which is obtained from 21-channel filter-bank outputs, for the classification of pathological voices. A simple k-means nearest neighbor classifier based on spectral distance is designed and a good classification results have been reported.

关键词： Nearest neighbor searches Pathology Speech enhancement Noise level Frequency Band pass filters Speech analysis Testing biomedical computing Humans

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Storage system support for continuous media applications, part 2: Multiple disks, memory, and integration

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IEEE Distributed Systems Online 2004年第2期5卷 1-1页

作者： Halvorsen, Pål Griwodz, Carsten Goebel, Vera Lund, Ketil Plagemann, Thomas Walpole, Jonathan University of Oslo Oregon Health and Science University Dept. of Informatics Univ. of Oslo PO Box 1080 Blindern N-0316 Oslo Norway UniK-Univ. Graduate Center PO Box 70 N-2027 Kjeller Norway Dept. of Computer Science and Eng. Oregon Grad. Inst. Sci./Technology 20000 N.W. Walker Rd. Beaverton OR 97291-1000

To meet multimedia servers' increasing performance and scalability requirements, researchers must design multimedia storage system components that adapt to various workloads and requirements. They must also develo... 详细信息

关键词： Magnetic disk storage

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"UML-ising" formal techniques

Lecture Notes in Computer Science (including subseries Lectu...

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Lecture Notes in computer science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2004年 3147卷 423-450页

作者： Bjørner, Dines George, Chris W. Haxthausen, Anne E. Madsen, Christian Krog Holmslykke, Steffen Pěnička, Martin Computer Science and Engineering Dept. Informatics and Mathematical Modelling Inst. Technical University of Denmark DK-2800 Kgs. Lyngby Denmark UNU/IIST P.O.Box 3058 China Rovsing A/S Dyregårdsvej 2 DK-2740 Skovlunde Denmark Faculty of Transportation Czech Technical University Na Florenci 25 CZ-11000 Prague 1 Czech Republic

This invited paper presents a number of correlated specifications of example railway system problems. They use a variety of partially or fully integrated formal specification. The paper thus represents a mere repository of what we consider interesting case studies. The existence of the Unified Modeling Language [10,67,36,20] has caused, for one reason or another, the research community to try formalise one or another facet of UML. In this paper we report on another way to achieve what UML attempts to achieve: Broadness of application, convenience of notation, and multiplicity of views. Whether these different UML views are unified, integrated, correlated or merely co-located is for others to dispute. We also seek to support multiple views, but are also in no doubt that there must be sound, well defined relations between such views. We thus report on ways and means of integrating formal techniques such as RAISE (RSL) [58,59], Petri Nets [56,62,37,61,41], Message and Live Sequence Charts [42,43,44,64,13], Statecharts [23,24,26,27], RAISE with Timing (TRSL) [18,45,46], and TRSL with Duration Calculus [79,30]. In this way one achieves a firm foundation for combined uses of these formal development techniques, one that can be believably deployed for as wide a spectrum, or even a wider spectrum of software (and hardware) development, as, respectively than UML. © Springer-Verlag Berlin Heidelberg 2004.

关键词： Petri nets

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Modeling Demand for Inventory Management of Slow-Moving Items in Case of Reporting Errors

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IFAC Proceedings Volumes 2004年第4期37卷 27-32页

作者： Alexandre Dolgui Anatoly Pashkevich Maxim Pashkevich Scientific Methods for Industrial Management Dept. (MSGI) Industrial Engineering and Computer Sciences Center (G2I) Ecole de Mines de Saint Etienne 158 Cours Fauriel 42023 Saint Etienne France Robotic Laboratory Department of Automatic Control Belarusian State University of Informatics and Radioelectronics 6 P.Brovka St. Minsk 220027 Belarus Department of Mathematical Modeling and Data Analysis Faculty of Applied Mathematics and Computer Science Belarusian State University Skarina Av. 4 Minsk 220050 Belarus

The paper is devoted to the problem of modeling demand for inventory management of slow-moving items in the case of reporting errors. It is proposed a generalization of the beta-binomial demand model that takes into account possible reporting errors in the learning sample. For the new model, there are developed identification and forecasting algorithms that provide consistent estimators of the model parameters and mean square optimal forecasts. The efficiency of the proposed approach is illustrated by an application example for slow-moving car parts.

关键词： inventory control error correction statistical inference parameter estimation prediction methods

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Visions and strategies to improve evaluation of health information systems: Reflections and lessons based on the HIS-EVAL workshop in Innsbruck

Visions and strategies to improve evaluation of health infor...

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作者： Ammenwerth, Elske Brender, Jytte Nykänen, Pirkko Prokosch, Hans-Ulrich Rigby, Michael Talmon, Jan Univ. Hlth. Sci. Med. Info. T. Res. Grp. Assess. Hlth. Info. Syst. Innrain 98 6020 Innsbruck Austria Inst. of Hlth. Technol. and Science University of Aalborg Aalborg Denmark Department of Computer Sciences Tampere University Tampere Finland Dept. Med. Info. Biometr. E. University of Erlangen Erlangen Germany Ctr. for Hlth. Plan. and Management Keele University Keele United Kingdom Department of Medical Informatics Maastricht University Maastricht Netherlands

Background: Health care is entering the Information Society. It is evident that the use of modern information and communication technology offers tremendous opportunities to improve health care. However, there are also hazards associated with information technology in health care. Evaluation is a means to assess the quality, value, effects and impacts of information technology and applications in the health care environment, to improve health information applications and to enable the emergence of an evidence-based health informatics profession and practice. Objective: In order to identify and address the frequent problems of getting evaluation understood and recognised, to promote transdisciplinary exchange within evaluation research, and to promote European cooperation, the Exploratory Workshop on "New Approaches to the Systematic Evaluation of Health Information Systems" (HIS-EVAL) was organized by the University for Health sciences, Medical informatics and Technology (UMIT), Innsbruck, Austria, in April 2003 with sponsorship from the European science Foundation (ESF). Methods: The overall program was structured in three main parts: (a) discussion of problems and barriers to evaluation;(b) defining our visions and strategies with regard to evaluation of health information systems;and (c) organizing short-term and long-term activities to reach those visions and strategies. Results: The workshop participants agreed on the Declaration of Innsbruck (see Appendix B), comprising four observations and 12 recommendations with regard to evaluation of health information systems. Future activities comprise European networking as well as the development of guidelines and standards for evaluation studies. Conclusion: The HIS-EVAL workshop was intended to be the starting point for setting up a network of European scientists working on evaluation of health information systems, to obtain synergy effects by combining the research traditions from different evaluation fields, leadi

关键词： Medical imaging

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Preface

Lecture Notes in Computer Science (including subseries Lectu...

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Lecture Notes in computer science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) 2004年 3139卷 V-VI页

作者： Iida, Fumiya Pfeifer, Rolf Steels, Luc Kuniyoshi, Yasuo University of Zurich Artificial Intelligence Laboratory Department of Informatics Andreasstr. 15 Zurich Switzerland Vrije Universiteit Brussel Artificial Intelligence Laboratory and Sony Computer Science Laboratory Department of Informatics Pleinlaan 2 Brussels Belgium University of Tokyo School of Information Science and Technology Dept. of Mechano-Informatics Laboratory for Intelligent Systems and Informatics Engineering Bldg. 8 7-3-1 Hongo Bunkyo-kuTokyo Japan

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Exploiting functional decomposition for efficient parallel processing of multiple data analysis queries

Exploiting functional decomposition for efficient parallel p...

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International Parallel and Distributed Processing Symposium, IPDPS 2003

作者： Andrade, Henrique Kurc, Tahsin Sussman, Alan Saltz, Joel Dept. of Computer Science University of Maryland College ParkMD20742 United States Dept. of Biomedical Informatics Ohio State University ColumbusOH43210 United States

ISBN: (纸本)0769519261

Reuse is a powerful method for increasing system performance. In this paper, we examine functional decomposition for improving data and computation reuse and, therefore, overall query execution performance in the context of data analysis applications. Additionally, we look at the performance effects of using various projection primitives that make it possible to transform intermediate results generated by a query so that they can be reused by a new query. A satellite data analysis application is used to experimentally show the performance benefits achieved using functional decomposition and projection primitives. © 2003 IEEE.

关键词： Data handling

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Impact of high performance sockets on data intensive applications 12

Impact of high performance sockets on data intensive applica...

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12th IEEE International Symposium on High Performance Distributed Computing, HPDC 2003

作者： Balaji, Pavan Wu, Jiesheng Kurc, Tahsin Catalyurek, Umit Panda, Dhabaleswar K. Saltz, Joel Dept. of Computer and Information Science Ohio State University ColumbusOH43210 United States Dept. of Biomedical Informatics Ohio State University ColumbusOH43210 United States

ISBN: (纸本)0769519652

The challenging issues in supporting data intensive applications on clusters include efficient movement of large volumes of data between processor memories and efficient coordination of data movement and processing by a runtime support to achieve high performance. Such applications have several requirements such as guarantees in performance, scalability with these guarantees and adaptability to heterogeneous environments. With the advent of user-level protocols like the Virtual Interface Architecture (VIA) and the modern InfiniBand Architecture, the latency and bandwidth experienced by applications has approached to that of the physical network on clusters. In order to enable applications written on top of TCP/IP to take advantage of the high performance of these user-level protocols, researchers have come up with a number of techniques including User Level Sockets Layers over high performance protocols. In this paper, we study the performance and limitations of such substrate, referred to here as SocketVIA, using a component framework designed to provide runtime support for data intensive applications. The experimental results show that by reorganizing certain components of an application (in our case, the partitioning of a dataset into smaller data chunks), we can make significant improvements in application performance. This leads to a higher scalability of applications with performance guarantees. It also allows fine grained load balancing, hence making applications more adaptable to heterogeneity in resource availability. The experimental results also show that the different performance characteristics of SocketVIA allow a more efficient partitioning of data at the source nodes, thus improving the performance of the application up to an order of magnitude in some cases. © 2003 IEEE.

关键词： Application programs

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