Combination drug therapies are treatment regimens that involve two or more drugs, administered more commonly for patients with cancer, HIV, malaria, or tuberculosis. Currently there are over 350K articles in PubMed th...
Combination drug therapies are treatment regimens that involve two or more drugs, administered more commonly for patients with cancer, HIV, malaria, or tuberculosis. Currently there are over 350K articles in PubMed that use the combination drug therapy MeSH heading with at least 10K articles published per year over the past two decades. Extracting combination therapies from scientific literature inherently constitutes an n-ary relation extraction problem. Unlike in the general n-ary setting where n is fixed (e.g., drug-gene-mutation relations where n =3), extracting combination therapies is a special setting where n ≥2 is dynamic, depending on each instance. Recently, Tiktinsky et al. (NAACL 2022) introduced a first of its kind dataset, CombDrugExt, for extracting such therapies from literature. Here, we use a sequence-to-sequence style end-to-end extraction method to achieve an F1-Score of 66.7% on the CombDrugExt test set for positive (or effective) combinations. This is an absolute ≈5% F1-score improvement even over the prior best relation classification score with spotted drug entities (hence, not end-to-end). Thus our effort introduces a state-of-the-art first model for end-to-end extraction that is already superior to the best prior non end-to-end model for this task. Our model seamlessly extracts all drug entities and relations in a single pass and is highly suitable for dynamic n-ary extraction scenarios.
With the rapid growth of the Internet of Things (IoT) devices, a lot of IoT malware has been created, and the security against IoT malware, especially the family classification, has become a more important issue. Ther...
With the rapid growth of the Internet of Things (IoT) devices, a lot of IoT malware has been created, and the security against IoT malware, especially the family classification, has become a more important issue. There exist three requirements which classification systems must achieve: detection of new families, precise classification for sequential inputs, and being independent of computer architectures. However, existing methods do not satisfy them simultaneously. In this paper, we propose a realtime IoT malware classification system based on pending samples. In order to detect new families and to classify sequential inputs precisely, we introduce the concept of “pending samples”. This concept is useful when heterogeneous inputs which are difficult to classify instantly come into the system. This is because the system can postpone classifying them until similar samples come. Once similar samples are gathered, we regard these samples as a new cluster, meaning that detecting new families is achieved. Moreover, we use printable strings to satisfy the requirement of being independent of architectures because strings are common among different architectures. Our results show the ability to detect new families demonstrated by finding new clusters after applying our algorithm to the initial clusters. Furthermore, our new clustering algorithms achieves a 0.130 higher V-measure compared to the k-means algorithm, which is the representative clustering algorithm.
End-to-end relation extraction (E2ERE) is an important task in information extraction, more so for biomedicine as scientific literature continues to grow exponentially. E2ERE typically involves identifying entities (o...
详细信息
Large-scale CT image studies often suffer from a lack of homogeneity regarding radiomic characteristics due to the images acquired with scanners from different vendors or with different reconstruction algorithms. We p...
详细信息
The efforts that are being made to bolster indigenous knowledge for the m illennial generation need to be carried out using a technical strategy that is based on the industrial revolution 4.0 and is moving toward soci...
The efforts that are being made to bolster indigenous knowledge for the m illennial generation need to be carried out using a technical strategy that is based on the industrial revolution 4.0 and is moving toward society 5.0. Kujangs, which have a variety of motifs on their b lades and carry cultural wisdom values, need to be socialized using a method that takes a millennial technology perspective in order to be able to transform the difficulties of s ociety 5.0 into the strengths of the Sustainable Development Goals ( SDGs). The purpose of this study is to develop an instructional game based on the kujang motif by utilizing Augmented Reality techniques and putting them into practice using the Floyd-Warshall Algorithm. The game of kujang pamor is designed on the idea of a maze, and the path through the maze is constructed on the basis of the cleaver figures. The complexity of each of s even different routes through a three-dimensional maze that uses augmented reality serves as the basis for the g ame's leveling system. In a maze game with clever figures, the Floyd-Warshall algorithm is possible to optimize the search for the path that is the shortest distance between two points. The originality of this study lies in the fact that it utilizes augmented reality techniques while simultaneously searching for the path with the least distance in a maze game based on the kujang pamor.
The core aim of the internet of things is providing communication capability between huge numbers of different entities "things". The Abundance feature of connected devices to the emergence of many security ...
详细信息
We introduce a framework for acoustic measurement that allows everyday sounds into acoustic measurement test signals and standard test signals such as swept-sine and MLS (Maximum Length Sequence). The framework extend...
详细信息
Time-varying linear state-space models are powerful tools for obtaining mathematically interpretable representations of neural signals. For example, switching and decomposed models describe complex systems using laten...
One of the most common risks for individuals who are bedridden is the development of bedsores (Pressure Ulcers). The number of senior persons who are permanently disabled and semi-impaired is growing as the population...
One of the most common risks for individuals who are bedridden is the development of bedsores (Pressure Ulcers). The number of senior persons who are permanently disabled and semi-impaired is growing as the population ages. The conventional methods used to relieve bed sores tend to focus on the pressure distribution and very minimal focus is provided for therapy. In order to detect patterns of warning signs or pathogens that can be treated early to reduce morbidity and mortality as well as length and expense of hospitalization, it is crucial to continuously monitor the patient’s health while they are in the hospital. Healthcare workers continuously monitor the patient’s vital signs, making it simple and safe to shield the patient from unforeseen threats and to reduce harmful health issues. On the other hand, a major side effect of hospitalization is the impact of pressure ulcers on the bedridden patient as a result of strong shear forces. A pressure ulcer or bedsores is a damage to tissue that has been disturbed or lacks blood flow as a result of prolonged pressure and shear forces, and it can give the patient pain and discomfort. This review focuses on research articles that deals with monitoring as well as treatment of patients inflicted with pressure ulcers. Furthermore, we have also proposed a basic system and methodology that can be followed by others for future research work.
The sixth generation (6G) mobile communication system is expected to utilize millimeter wave and THz frequency bands, in addition to RF bands. The propagation characteristics and ranges of these bands vary vastly whil...
The sixth generation (6G) mobile communication system is expected to utilize millimeter wave and THz frequency bands, in addition to RF bands. The propagation characteristics and ranges of these bands vary vastly while the multi-band users supposedly experience seamless coverage, high throughput and consistent Quality of Service. Heterogeneous base stations (BSs) equipped with these multiple technologies shall be fairly loaded for this. SINR based approaches tend to assign more users to RF channels while starving other bandwidth rich mediums. In this paper, we propose an algorithm to improve the performance of multi-band 6G networks by optimizing the user association to heterogeneous BS to maximize the cumulative data rate while ensuring an acceptable transmission power and fair load balancing among the BSs. The optimization problem is solved using the Lagrangian method. Simulation results show an improved cumulative throughput and fairness.
暂无评论