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Considerations and recommendations from the ISMRM Diffusion Study Group for preclinical diffusion MRI: Part 3 — Ex vivo imaging: data processing, comparisons with microscopy, and tractography

arXiv

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arXiv 2024年

作者： Schilling, Kurt G. Howard, Amy F.D. Grussu, Francesco Ianus, Andrada Hansen, Brian Barrett, Rachel L.C. Aggarwal, Manisha Michielse, Stijn Nasrallah, Fatima Syeda, Warda Wang, Nian Veraart, Jelle Roebroeck, Alard Bagdasarian, Andrew F. Eichner, Cornelius Sepehrband, Farshid Zimmermann, Jan Soustelle, Lucas Bowman, Christien Tendler, Benjamin C. Hertanu, Andreea Jeurissen, Ben Verhoye, Marleen Frydman, Lucio van de Looij, Yohan Hike, David Dunn, Jeff F. Miller, Karla Landman, Bennett A. Shemesh, Noam Anderson, Adam McKinnon, Emilie Farquharson, Shawna Dell' Acqua, Flavio Pierpaoli, Carlo Drobnjak, Ivana Leemans, Alexander Harkins, Kevin D. Descoteaux, Maxime Xu, Duan Huang, Hao Santin, Mathieu D. Grant, Samuel C. Obenaus, Andre Kim, Gene S. Wu, Dan Le Bihan, Denis Blackband, Stephen J. Ciobanu, Luisa Fieremans, Els Bai, Ruiliang Leergaard, Trygve B. Zhang, Jiangyang Dyrby, Tim B. Johnson, G. Allan Cohen-Adad, Julien Budde, Matthew D. Jelescu, Ileana O. Radiology and Radiological Sciences Vanderbilt University Medical Center NashvilleTN United States Vanderbilt University Institute of Imaging Science Vanderbilt University NashvilleTN United States Department of Bioengineering Imperial College London London United Kingdom FMRIB Centre Wellcome Centre for Integrative Neuroimaging Nuffield Department of Clinical Neurosciences University of Oxford Oxford United Kingdom Radiomics Group Vall d’Hebron Institute of Oncology Vall d’Hebron Barcelona Hospital Campus Barcelona Spain Queen Square MS Centre Queen Square Institute of Neurology Faculty of Brain Sciences University College London London United Kingdom Champalimaud Research Champalimaud Foundation Lisbon Portugal Center of Functionally Integrative Neuroscience Aarhus University Aarhus Denmark Department of Neuroimaging Institute of Psychiatry Psychology and Neuroscience King's College London London United Kingdom NatBrainLab Department of Forensics and Neurodevelopmental Sciences Institute of Psychiatry Psychology and Neuroscience King's College London London United Kingdom Russell H. Morgan Department of Radiology and Radiological Science Johns Hopkins University School of Medicine BaltimoreMD United States Maastricht University Medical Center Maastricht Netherlands The Queensland Brain Institute The University of Queensland Queensland Australia Melbourne Neuropsychiatry Centre The University of Melbourne ParkvilleVIC Australia Department of Radiology and Imaging Sciences Indiana University IN United States Stark Neurosciences Research Institute Indiana University School of Medicine IN United States Center for Biomedical Imaging NYU Grossman School of Medicine New YorkNY United States Faculty of psychology and Neuroscience Maastricht University Maastricht Netherlands Department of Chemical & Biomedical Engineering FAMU-FSU College of Engineering Florida State University TallahasseeFL United States Center for Interdisciplinary Magnetic Res

Preclinical diffusion MRI (dMRI) has proven value in methods development and validation, characterizing the biological basis of diffusion phenomena, and comparative anatomy. While dMRI enables in vivo non-invasive characterization of tissue, ex vivo dMRI is increasingly being used to probe tissue microstructure and brain connectivity. Ex vivo dMRI has several experimental advantages that facilitate high spatial resolution and high signal-to-noise ratio (SNR) images, cutting-edge diffusion contrasts, and direct comparison with histological data as a methodological validation. However, there are a number of considerations that must be made when performing ex vivo experiments. The steps from tissue preparation, image acquisition and processing, and interpretation of results are complex, with many decisions that not only differ dramatically from in vivo imaging of small animals, but ultimately affect what questions can be answered using the data. This work concludes a 3-part series of recommendations and considerations for preclinical dMRI. Herein, we describe best practices for dMRI of ex vivo tissue, with a focus on image pre-processing, data processing and model fitting, and tractography. In each section, we attempt to provide guidelines and recommendations, but also highlight areas for which no guidelines exist (and why), and where future work should lie. We end by providing guidelines on code sharing and data sharing, and point towards open-source software and databases specific to small animal and ex vivo imaging. © 2024, CC BY.

关键词： Data Sharing

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High-throughput segmentation of unmyelinated axons by deep learning

Research Square

引用

Research Square 2021年

作者： Plebani, Emanuele Biscola, Natalia P. Havton, Leif A. Rajwa, Bartek Shemonti, Abida Sanjana Jaffey, Deborah Powley, Terry Keast, Janet R. Lu, Kun-Han Dundar, M. Murat Dept. of Computer & Information Sciences Indiana University - Purdue University IndianapolisIN46202 United States Dept. of Neurology Icahn School of Medicine at Mount Sinai New YorkNY10029 United States Dept. of Neuroscience Icahn School of Medicine at Mount Sinai New YorkNY10029 United States James J. Peters Department of Veterans Affairs Medical Center BronxNY10468 United States Bindley Bioscience Center Purdue University West LafayetteIN47906 United States Dept. of Computer Science Purdue University West LafayetteIN47906 United States Dept. of Psychological Sciences Purdue University West LafayetteIN47907 United States Dept. of Anatomy and Physiology The University of Melbourne MelbourneVIC3010 Australia Weldon School of Biomedical Engineering Purdue University West LafayetteIN47907 United States

Axonal characterizations of connectomes in healthy and disease phenotypes are surprisingly incomplete and biased because unmyelinated axons, the most prevalent type of fibers in the nervous system, have largely been ignored as their quantitative assessment quickly becomes unmanageable as the number of axons increases. Herein, we introduce the first prototype of a high-throughput processing pipeline for automated segmentation of unmyelinated fibers. Our team has used transmission electron microscopy images of vagus and pelvic nerves in rats. All unmyelinated axons in these images are individually annotated and used as labeled data to train and validate a deep instance segmentation network. We investigate the effect of different training strategies on the overall segmentation accuracy of the network. We extensively validate the segmentation algorithm as a stand-alone segmentation tool as well as in an expert-in-the-loop hybrid segmentation setting with preliminary, albeit remarkably encouraging results. Our algorithm achieves an instance-level F1 score of between 0.7 and 0.9 on various test images in the stand-alone mode and reduces expert annotation labor by 80% in the hybrid setting. We hope that this new high-throughput segmentation pipeline will enable quick and accurate characterization of unmyelinated fibers at scale and become instrumental in significantly advancing our understanding of connectomes in both the peripheral and the central nervous systems. © 2021, CC BY.

关键词： Fibers

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Roadmap on Deep Learning for Microscopy

arXiv

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arXiv 2023年

作者： Volpe, Giovanni Wählby, Carolina Tian, Lei Hecht, Michael Yakimovich, Artur Monakhova, Kristina Waller, Laura Sbalzarini, Ivo F. Metzler, Christopher A. Xie, Mingyang Zhang, Kevin Lenton, Isaac C.D. Rubinsztein-Dunlop, Halina Brunner, Daniel Bai, Bijie Ozcan, Aydogan Midtvedt, Daniel Wang, Hao Sladoje, Nataša Lindblad, Joakim Smith, Jason T. Ochoa, Marien Barroso, Margarida Intes, Xavier Qiu, Tong Yu, Li-Yu You, Sixian Liu, Yongtao Ziatdinov, Maxim A. Kalinin, Sergei V. Sheridan, Arlo Manor, Uri Nehme, Elias Goldenberg, Ofri Shechtman, Yoav Moberg, Henrik K. Langhammer, Christoph Špačková, Barbora Helgadottir, Saga Midtvedt, Benjamin Argun, Aykut Thalheim, Tobias Cichos, Frank Bo, Stefano Hubatsch, Lars Pineda, Jesus Manzo, Carlo Bachimanchi, Harshith Selander, Erik Homs-Corbera, Antoni Fränzl, Martin de Haan, Kevin Rivenson, Yair Korczak, Zofia Adiels, Caroline Beck Mijalkov, Mite Veréb, Dániel Chang, Yu-Wei Pereira, Joana B. Matuszewski, Damian Kylberg, Gustaf Sintorn, Ida-Maria Caicedo, Juan C. Cimini, Beth A. Bell, Muyinatu Lediju A. Saraiva, Bruno M. Jacquemet, Guillaume Henriques, Ricardo Ouyang, Wei Le, Trang Gómez-De-Mariscal, Estibaliz Sage, Daniel Muñoz-Barrutia, Arrate Lindqvist, Ebba Josefson Bergman, Johanna Department of Physics University of Gothenburg Gothenburg41296 Sweden Dept. IT and SciLifeLab Uppsala University Sweden Department of Electrical and Computer Engineering Boston University BostonMA02215 United States Department of Biomedical Engineering Boston University BostonMA02215 United States Görlitz Germany Department of Renal Medicine Division of Medicine University College London Royal Free Hospital Campus London United Kingdom Artificial Intelligence for Life Sciences CIC Dorset United Kingdom Roche Pharma International Informatics Roche Diagnostics GmbH Mannheim Germany Department of Electrical Engineering and Computer Sciences UC Berkeley United States Technische Universität Dresden Faculty of Computer Science Dresden Germany Max Planck Institute of Molecular Cell Biology and Genetics Center for Systems Biology Dresden Dresden Germany University of Maryland College Park United States Klosterneuburg3400 Austria School of Mathematics and Physics The University of Queensland Brisbane4072 Australia Australian Research Council Centre of Excellence for Engineered Quantum Systems The University of Queensland Brisbane4072 Australia Département d’Optique P. M. Duffieux Institut FEMTO-ST Université Franche-Comté CNRS UMR 6174 Besançon France Department of Electrical and Computer Engineering University of California Los Angeles Los AngelesCA United States Department of Information Technology Uppsala University Sweden Department of Biomedical Engineering Rensselaer Polytechnic Institute TroyNY12180 United States Elephas 1 Erdman Pl. Madison53705 United States University of Wisconsin–Madison Department of Medical Physics MadisonWI53705 United States Department of Molecular and Cellular Physiology Albany Medical College AlbanyNY12208 United States Research Laboratory of Electronics Electrical Engineering and Computer Science Massachusetts Institute of Technology BostonMA United States Center for Nanophase Materials Sciences Oak R

Through digital imaging, microscopy has evolved from primarily being a means for visual observation of life at the micro- and nano-scale, to a quantitative tool with ever-increasing resolution and throughput. Artificial intelligence, deep neural networks, and machine learning are all niche terms describing computational methods that have gained a pivotal role in microscopy-based research over the past decade. This Roadmap is written collectively by prominent researchers and encompasses selected aspects of how machine learning is applied to microscopy image data, with the aim of gaining scientific knowledge by improved image quality, automated detection, segmentation, classification and tracking of objects, and efficient merging of information from multiple imaging modalities. We aim to give the reader an overview of the key developments and an understanding of possibilities and limitations of machine learning for microscopy. It will be of interest to a wide cross-disciplinary audience in the physical sciences and life sciences. Copyright © 2023, The Authors. All rights reserved.

关键词： Image enhancement

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A large-scale multicenter breast cancer DCE-MRI benchmark dataset with expert segmentations

arXiv

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arXiv 2024年

作者： Garrucho, Lidia Kushibar, Kaisar Reidel, Claire-Anne Joshi, Smriti Osuala, Richard Tsirikoglou, Apostolia Bobowicz, Maciej del Riego, Javier Catanese, Alessandro Gwoździewicz, Katarzyna Cosaka, Maria-Laura Abo-Elhoda, Pasant M. Tantawy, Sara W. Sakrana, Shorouq S. Shawky-Abdelfatah, Norhan O. Abdo-Salem, Amr Muhammad Kozana, Androniki Divjak, Eugen Ivanac, Gordana Nikiforaki, Katerina Klontzas, Michail E. García-Dosdá, Rosa Gulsun-Akpinar, Meltem Lafcı, Oğuz Mann, Ritse Martín-Isla, Carlos Prior, Fred Marias, Kostas Starmans, Martijn P.A. Strand, Fredrik Díaz, Oliver Igual, Laura Lekadir, Karim Barcelona Spain Department of Oncology-Pathology Karolinska Institutet Stockholm Sweden Institute of Machine Learning in Biomedical Imaging Helmholtz Center Munich Munich Germany School of Computation Information and Technology Technical University of Munich Munich Germany 2nd Dept. of Radiology Medical University of Gdansk Gdansk Poland Parc Taulí Hospital Universitari Sabadell Spain Hospital Germans Trias i Pujol Badalona Spain Centro Mamario Instituto Alexander Fleming Buenos Aires Argentina Department of Diagnostic & Interventional Radiology and Molecular Imaging Faculty of Medicine Ain Shams University Cairo Egypt Department of Radiology University Hospital of Heraklion Stavrakia Greece Department of Diagnostic and Interventional Radiology University Hospital Dubrava Zagreb Croatia University of Zagreb School of Medicine Zagreb Croatia Computational BioMedicine Laboratory Institute of Computer Science Foundation for Research and Technology—Hellas Heraklion Greece Department of Radiology School of Medicine University of Crete Heraklion Greece Medical Imaging and Radiology Universitary and Politechnic Hospital La Fe Valencia Spain Department of Radiology Hacettepe University Faculty of Medicine Sihhiye Ankara Turkey Department of Biomedical Imaging and Image-guided Therapy Medical University of Vienna Vienna Austria Department of Radiology and Nuclear Medicine Radboud University Medical Center Netherlands University of Arkansas for Medical Sciences Little RockAR United States Department of Electrical and Computer Engineering Hellenic Mediterranean University Heraklion Greece Heraklion Greece Department of Radiology and Nuclear Medicine Erasmus MC Cancer Institute University Medical Center Rotterdam Rotterdam Netherlands Department of Pathology Erasmus MC Cancer Institute University Medical Center Rotterdam Rotterdam Netherlands Breast Radiology Karolinska University Hospital Stockholm Sweden Passeig Lluís Companys 23 Barcelona Sp

Artificial Intelligence (AI) research in breast cancer Magnetic Resonance Imaging (MRI) faces challenges due to limited expert-labeled segmentations. To address this, we present a multicenter dataset of 1506 pretreatment T1-weighted dynamic contrast-enhanced MRI cases, including expert annotations of primary tumors and non-mass-enhanced regions. The dataset integrates imaging data from four collections in The Cancer Imaging Archive (TCIA), where only 163 cases with expert segmentations were initially available. To facilitate the annotation process, a deep learning model was trained to produce preliminary segmentations for the remaining cases. These were subsequently corrected and verified by 16 breast cancer experts (averaging 9 years of experience), creating a fully annotated dataset. Additionally, the dataset includes 49 harmonized clinical and demographic variables, as well as pre-trained weights for a baseline nnU-Net model trained on the annotated data. This resource addresses a critical gap in publicly available breast cancer datasets, enabling the development, validation, and benchmarking of advanced deep learning models, thus driving progress in breast cancer diagnostics, treatment response prediction, and personalized care. Copyright © 2024, The Authors. All rights reserved.

关键词： Dynamic contrast enhanced MRI

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Automatic Diagnosis of Schizophrenia in EEG Signals Using CNN-LSTM Models

arXiv

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arXiv 2021年

作者： Shoeibi, Afshin Sadeghi, Delaram Moridian, Parisa Ghassemi, Navid Heras, Jonathan Alizadehsani, Roohallah Khadem, Ali Kong, Yinan Nahavandi, Saeid Zhang, Yu-Dong Gorriz, Juan M. The Faculty of Electrical Engineering K. N. Toosi University of Technology Tehran Iran The Dept. of Medical Engineering Mashhad Branch Islamic Azad University Mashhad Iran The Faculty of Engineering Science and Research Branch Islamic Azad University Tehran Iran The Department of Mathematics and Computer Science University of la Rioja La Rioja Spain Deakin University VIC3217 Australia The School of Engineering Macquarie University Sydney2109 Australia The Harvard Paulson School of Engineering and Applied Sciences Harvard University AllstonMA02134 United States The Department of Informatics University of Leicester Leicester United Kingdom The Department of Signal Theory Networking and Communications Universidad de Granada Spain The Department of Psychiatry. University of Cambridge United Kingdom

Schizophrenia (SZ) is a mental disorder whereby due to the secretion of specific chemicals in the brain, the function of some brain regions is out of balance, leading to the lack of coordination between thoughts, actions, and emotions. This study provides various intelligent deep learning (DL)-based methods for automated SZ diagnosis via electroencephalography (EEG) signals. The obtained results are compared with those of conventional intelligent methods. To implement the proposed methods, the dataset of the Institute of Psychiatry and Neurology in Warsaw, Poland, has been used. First, EEG signals were divided into 25 s time frames and then were normalized by z-score or norm L2. In the classification step, two different approaches were considered for SZ diagnosis via EEG signals. In this step, the classification of EEG signals was first carried out by conventional machine learning methods, e.g., support vector machine, k-nearest neighbors, decision tree, naïve Bayes, random forest, extremely randomized trees, and bagging. Various proposed DL models, namely, long short-term memories (LSTMs), one-dimensional convolutional networks (1D-CNNs), and 1DCNN-LSTMs, were used in the following. In this step, the DL models were implemented and compared with different activation functions. Among the proposed DL models, the CNN-LSTM architecture has had the best performance. In this architecture, the ReLU activation function with the z-score and L2-combined normalization was used. The proposed CNN-LSTM model has achieved an accuracy percentage of 99.25. © 2021, CC BY-NC-ND.

关键词： Diseases

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Metrics Reloaded: Recommendations for image analysis validation

arXiv

引用

arXiv 2022年

作者： Maier-Hein, Lena Reinke, Annika Godau, Patrick Tizabi, Minu D. Buettner, Florian Christodoulou, Evangelia Glocker, Ben Isensee, Fabian Kleesiek, Jens Kozubek, Michal Reyes, Mauricio Riegler, Michael A. Wiesenfarth, Manuel Emre Kavur, A. Sudre, Carole H. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Rädsch, Tim Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Jorge Cardoso, M. Cheplygina, Veronika Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian Ginneken, Bram Van Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kofler, Florian Kopp-Schneider, Annette Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rajpoot, Nasir Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Smeden, Maarten Van Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. Calster, Ben Van Varoquaux, Gaël Jäger, Paul F. Heidelberg Division of Intelligent Medical Systems and HI Helmholtz Imaging Germany Faculty of Mathematics and Computer Science and Medical Faculty Heidelberg University Heidelberg Germany NCT Heidelberg a partnership between DKFZ University Medical Center Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt-Marburg Germany Heidelberg Goethe University Frankfurt Germany Department of Medicine Goethe University Frankfurt Germany Department of Informatics Frankfurt Cancer Insititute Germany Department of Computing Imperial College London London United Kingdom Heidelberg Division of Medical Image Computing and HI Applied Computer Vision Lab Germany Institute for AI in Medicine University Medicine Essen Essen Germany Centre for Biomedical Image Analysis Faculty of Informatics Masaryk University Brno Czech Republic ARTORG Center for Biomedical Engineering Research University of Bern Bern Switzerland Department of Radiation Oncology University Hospital Bern University of Bern Bern Switzerland Simula Metropolitan Center for Digital Engineering Oslo Norway UiT The Arctic University of Norway Romsø Norway Heidelberg Division of Biostatistics Germany Heidelberg Division of Intelligent Medical Systems Division of Medical Image Computing HI Applied Computer Vision Lab Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Heidelberg Division of Medical Image Computing Germany Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montréal

Increasing evidence shows that flaws in machine learning (ML) algorithm validation are an underestimated global problem. Particularly in automatic biomedical image analysis, chosen performance metrics often do not reflect the domain interest, thus failing to adequately measure scientific progress and hindering translation of ML techniques into practice. To overcome this, we created Metrics Reloaded, a comprehensive framework guiding researchers in the problem-aware selection of metrics. It was developed by a large international consortium in a multi-stage Delphi process and is based on the novel concept of a problem fingerprint – a structured representation of the given problem that captures all aspects that are relevant for metric selection, from the domain interest to the properties of the target structure(s), data set and algorithm output. Based on the problem fingerprint, users are guided through the process of choosing and applying appropriate validation metrics while being made aware of potential pitfalls. Metrics Reloaded targets image analysis problems that can be interpreted as a classification task at image, object or pixel level, namely image-level classification, object detection, semantic segmentation, and instance segmentation tasks. To improve the user experience, we implemented the framework in the Metrics Reloaded online tool. Following the convergence of ML methodology across application domains, Metrics Reloaded fosters the convergence of validation methodology. Its applicability is demonstrated for various biomedical use cases. © 2022, CC BY.

关键词： Semantic Segmentation

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Traits: An object oriented dynamic type system for reasoning with unstructured data in a type safe environment. 13

Traits: An object oriented dynamic type system for reasoning...

引用

13th RuleML+RR Doctoral Consortium and Rule Challenge, RuleML+RR DC and Challenge 2019

作者： Sottara, Davide Proctor, Mark Bragaglia, Stefano Hekmatnejad, Mohammad Biomedical Informatics Department Arizona State University 13212 East Shea Boulevard ScottsdaleAZ85259 United States Computer Science Department Arizona State University TempeAZ85281 United States Context Scout London United Kingdom Dept. of Electrical and Electronic Engineering Imperial College London London United Kingdom Red Hat WestfordMA United States

This paper describes "traits", an extension to a rule engine that provides a dynamic type system for working with in an object oriented code in a type safe environment. This extension is inspired by frame logic and "duck typing". The implementation is based on the use of dynamic proxies and form of runtime interface injection and requires the partial redefinition of the traditional working memory operations (assert, update, retract), but is otherwise transparently embedded in the engine. We evaluate a reference implementation built on top of the open source rule engine Drools, showing that the approach improves clarity without impacting performance. Copyright © 2019 for this paper by its authors. Use permitted under Creative Commons License Attribution 4.0 International (CC BY 4.0).

关键词： Engines

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Enhance the Mammogram Images for Both Segmentation and Feature Extraction Using Wavelet Transform

Enhance the Mammogram Images for Both Segmentation and Featu...

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2019 International Conference on Advanced science and engineering, ICOASE 2019

作者： Zebari, Dilovan Asaad Haron, Habibollah Zeebaree, Subhi R.M. Zeebaree, Diyar Qader Faculty of Engineering School of Computing University Teknologi Malaysia Johor Malaysia University Teknologi Malaysia Faculty of Computing Department of Computer Science Johor Malaysia IT Dept. Technical College of Informatics Akre Duhok Scientific Research and Development Center Nawroz University Duhok Iraq

ISBN: (纸本)9781538693438

Breast cancer (BC) is a main killer disease for women and men. It can be cured and controlled only if it is detected at its early detection. BC initial identification can be realized by the help of computer support identification approaches. From the detailed study on previous researches, it is found that, there is no system producing high accuracy because of one or more reasons. Absence of effective preprocessing is the discussed reason that obstructs the detection accuracy of computer-Aided diagnosis (CAD) method. Noise removal and contrast enhancement are the two types of preprocessing. There is no system performs the preprocessing on mammogram image. This work is an attempt to develop an enhanced preprocessing method for CAD of breast cancer by incorporating suitable noise reduction and contrast enhancement methods in the conventional CAD system. Contrast enhancement after noise reduction double enhances the mammogram image and the proposed methods MSE value for the mammogram image mdb072 has been 1.44% reduced. Reduction in MSE increases the PSNR to 0.16%. Many mammogram images have been tested and the result shows that, increase in contrast, decrease in mean square error and increase in peak signal to noise ratio when comparing to existing methods. © 2019 IEEE.

关键词： Wavelet transforms

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State of the Art of Audio- and Video-Based Solutions for AAL

arXiv

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arXiv 2022年

作者： Aleksic, Slavisa Atanasov, Michael Agius, Jean Calleja Camilleri, Kenneth Čartolovni, Anto Climent-Pérez, Pau Colantonio, Sara Cristina, Stefania Despotovic, Vladimir Ekenel, Hazım Kemal Erakin, Ekrem Florez-Revuelta, Francisco Germanese, Danila Grech, Nicole Sigurðardóttir, Steinunn Gróa Emirzeoğlu, Murat Iliev, Ivo Jovanovic, Mladjan Kampel, Martin Kearns, William Klimczuk, Andrzej Lambrinos, Lambros Lumetzberger, Jennifer Mucha, Wiktor Noiret, Sophie Pajalic, Zada Pérez, Rodrigo Rodriguez Petrova, Galidiya Petrovica, Sintija Pocta, Peter Poli, Angelica Pudane, Mara Spinsante, Susanna Salah, Albert Ali Santofimia, Maria Jose Islind, Anna Sigríður Stoicu-Tivadar, Lacramioara Tellioğlu, Hilda Zgank, Andrej Leipzig University of Applied Sciences Germany TU Wien Austria Department of Anatomy University of Malta Malta Centre for Biomedical Cybernetics Faculty of Engineering Department of Systems and Control Engineering Malta Catholic University of Croatia Croatia Universidad de Alicante Spain Institute of Information Science and Technologies The National Research Council of Italy Italy Department of Systems and Control Engineering University of Malta Malta University of Luxembourg Luxembourg Dept. of Computer Engineering Istanbul Technical University Turkey Reykjavik University School of Computer Science Iceland Sağlık Bilimleri Fakültesi Fizyoterapi ve Rehabilitasyon Karadeniz Technical University Research Information System Turkey TU Sofia Bulgaria Singidunum University Belgrade Serbia University of South Florida United States SGH Warsaw School of Economics Poland Department of Communication and Internet Studies Cyprus University of Technologies Cyprus Technical University of Vienna Austria VID Specialized University Oslo Norway Getafe University Hospital Spain Riga Technical University Latvia University of Zilina Slovakia Università Politecnica Marche Italy Utrecht University Netherlands Universidad de Castilla-La Mancha Spain Reykjavik University Iceland University Politehnica Timisoara Romania University of Maribor Slovenia

It is a matter of fact that Europe is facing more and more crucial challenges regarding health and social care due to the demographic change and the current economic context. The recent COVID-19 pandemic has stressed this situation even further, thus highlighting the need for taking action. Active and Assisted Living (AAL) technologies come as a viable approach to help facing these challenges, thanks to the high potential they have in enabling remote care and support. Broadly speaking, AAL can be referred to as the use of innovative and advanced Information and Communication Technologies to create supportive, inclusive and empowering applications and environments that enable older, impaired or frail people to live independently and stay active longer in society. AAL capitalizes on the growing pervasiveness and effectiveness of sensing and computing facilities to supply the persons in need with smart assistance, by responding to their necessities of autonomy, independence, comfort, security and safety. The application scenarios addressed by AAL are complex, due to the inherent heterogeneity of the end-user population, their living arrangements, and their physical conditions or impairment. Despite aiming at diverse goals, AAL systems should share some common characteristics. They are designed to provide support in daily life in an invisible, unobtrusive and user-friendly manner. Moreover, they are conceived to be intelligent, to be able to learn and adapt to the requirements and requests of the assisted people, and to synchronise with their specific needs. Nevertheless, to ensure the uptake of AAL in society, potential users must be willing to use AAL applications and to integrate them in their daily environments and lives. In this respect, video- and audio-based AAL applications have several advantages, in terms of unobtrusiveness and information richness. Indeed, cameras and microphones are far less obtrusive with respect to the hindrance other wearable sensors may

关键词： computer vision

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Stability Analysis of Heartbeat Control Based on the Zeeman Framework

Stability Analysis of Heartbeat Control Based on the Zeeman ...

引用

IEEE International Conference on Intelligent Data Acquisition and Advanced Computing Systems

作者： Mohamed Abdelhady Yuriy Kondratenko Wael Abouelwafa Dan Simon Cleveland State University Electrical Engineering and Computer Science Dept. Petro Mohyla Black Sea National University Intelligent Information Systems Dept. Minia University Biomedical Engineering Department

Nonlinear control stability of a heart beat tracking system is investigated in this paper based on second-order original and third-order modified Zeeman's heartbeat models. Stability analysis shows that the third-... 详细信息

ISBN: (纸本)9781728140704

关键词： ECG Zeeman Stability analysis Heartbeat Heart beat Stability analysis Electrocardiography electrochemical grinding

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