The rapid advancements in big data and the Internet of Things (IoT) have significantly accelerated the digital transformation of medical institutions, leading to the widespread adoption of Digital Twin Healthcare (DTH...
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The rapid advancements in big data and the Internet of Things (IoT) have significantly accelerated the digital transformation of medical institutions, leading to the widespread adoption of Digital Twin Healthcare (DTH). The Cloud DTH Platform (CDTH) serves as a cloud-based framework that integrates DTH models, healthcare resources, patient data, and medical services. By leveraging real-time data from medical devices, the CDTH platform enables intelligent healthcare services such as disease prediction and medical resource optimization. However, the platform functions as a system of systems (SoS), comprising interconnected yet independent healthcare services. This complexity is further compounded by the integration of both black-box AI models and domain-specific mechanistic models, which pose challenges in ensuring the interpretability and trustworthiness of DTH models. To address these challenges, we propose a Model-Based systemsengineering (MBSE)-driven DTH modeling methodology derived from systematic requirement and functional analyses. To implement this methodology effectively, we introduce a DTH model development approach using the X language, along with a comprehensive toolchain designed to streamline the development process. Together, this methodology and toolchain form a robust framework that enables engineers to efficiently develop interpretable and trustworthy DTH models for the CDTH platform. By integrating domain-specific mechanistic models with AI algorithms, the framework enhances model transparency and reliability. Finally, we validate our approach through a case study involving elderly patient care, demonstrating its effectiveness in supporting the development of DTH models that meet healthcare and interpretability requirements.
This book constitutes the refereed proceedings of the 38th Conference on Current Trends in Theory and Practice of computerscience, SOFSEM 2012, held in Špindlerův Mlýn, Czech Republic, in January 2012. The 43 re...
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ISBN:
(数字)9783642276606
ISBN:
(纸本)9783642276590
This book constitutes the refereed proceedings of the 38th Conference on Current Trends in Theory and Practice of computerscience, SOFSEM 2012, held in Špindlerův Mlýn, Czech Republic, in January 2012.
The 43 revised papers presented in this volume were carefully reviewed and selected from 121 submissions. The book also contains 11 invited talks, 10 of which are in full-paper length. The contributions are organized in topical sections named: foundations of computerscience; software and Web engineering; cryptography, security, and verification; and artificial intelligence.
This book constitutes the refereed proceedings of the International Conference for Smart Health, ICSH 2013, held in Beijing, China, in August 2013. The 15 revised full papers presented were carefully reviewed and sele...
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ISBN:
(数字)9783642398445
ISBN:
(纸本)9783642398438
This book constitutes the refereed proceedings of the International Conference for Smart Health, ICSH 2013, held in Beijing, China, in August 2013. The 15 revised full papers presented were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on information Sharing, Integrating and Extraction; Mining Clinical and Medical Data; Smart Health Applications.
th This publication comprises the proceedings of the 29 International Conference on Conceptual Modeling (ER 2010), which was held this year in Vancouver, British Columbia, Canada. Conceptual modeling can be considered...
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ISBN:
(数字)9783642163739
ISBN:
(纸本)9783642163722
th This publication comprises the proceedings of the 29 International Conference on Conceptual Modeling (ER 2010), which was held this year in Vancouver, British Columbia, Canada. Conceptual modeling can be considered as lying at the confluence of the three main aspects of information technology applications –– the world of the stakeholders and users, the world of the developers, and the technologies available to them. C- ceptual models provide abstractions of various aspects related to the development of systems, such as the application domain, user needs, database design, and software specifications. These models are used to analyze and define user needs and system requirements, to support communications between stakeholders and developers, to provide the basis for systems design, and to document the requirements for and the design rationale of developed systems. Because of their role at the junction of usage, development, and technology, c- ceptual models can be very important to the successful development and deployment of IT applications. Therefore, the research and development of methods, techniques, tools and languages that can be used in the process of creating, maintaining, and using conceptual models is of great practical and theoretical importance. Such work is c- ducted in academia, research institutions, and industry. Conceptual modeling is now applied in virtually all areas of IT applications, and spans varied domains such as organizational informationsystems, systems that include specialized data for spatial, temporal, and multimedia applications, and biomedical applications.
Some of the most challenging problems in science and engineering are being addressed by the integration of computation and science, a research ?eld known as computational science. Computational science plays a vital r...
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ISBN:
(数字)9783540448600
ISBN:
(纸本)9783540401940
Some of the most challenging problems in science and engineering are being addressed by the integration of computation and science, a research ?eld known as computational science. Computational science plays a vital role in fundamental advances in biology, physics, chemistry, astronomy, and a host of other disciplines. This is through the coordination of computation, data management, access to instrumentation, knowledge synthesis, and the use of new devices. It has an impact on researchers and practitioners in the sciences and beyond. The sheer size of many challenges in computational science dictates the use of supercomputing, parallel and distri- ted processing, grid-based processing, advanced visualization and sophisticated algorithms. At the dawn of the 21st century the series of International Conferences on Computational science (ICCS) was initiated with a ?rst meeting in May 2001 in San Francisco. The success of that meeting motivated the organization of the - cond meeting held in Amsterdam April 21–24, 2002, where over 500 participants pushed the research ?eld further. The International Conference on Computational science 2003 (ICCS 2003) is the follow-up to these earlier conferences. ICCS 2003 is unique, in that it was a single event held at two di?erent sites almost opposite each other on the globe – Melbourne, Australia and St. Petersburg, Russian Federation. The conference ran on the same dates at both locations and all the presented work was published in a single set of proceedings, which you hold in your hands right now.
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