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Mapping abnormal subcortical brain morphometry in an elderly HIV+ cohort 12

Mapping abnormal subcortical brain morphometry in an elderly...

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12th IEEE International Symposium on Biomedical Imaging, ISBI 2015

作者： Wade, Benjamin S. C. Valcour, Victor G. Wendelken-Riegelhaupt, Lauren Esmaeili-Firidouni, Pardis Joshi, Shantanu H. Wang, Yalin Thompson, Paul M. Imaging Genetics Center University of Southern California Los AngelesCA United States Memory and Aging Center Dept. of Neurology University of California San FranciscoCA United States Ahmanson-Lovelace Brain Mapping Center Department of Neurology UCLA CA United States School of Computing Informatics and Decision Systems Engineering Arizona State University TempeAZ United States

ISBN: (纸本)9781479923748

Over 50% of HIV+ individuals exhibit neurocognitive impairment and subcortical atrophy, but the pattern of brain abnormalities associated with HIV is still poorly understood. Using parametric surface-based shape analyses, we mapped the 3D profile of subcortical morphometry in 63 HIV+ participants and 31 uninfected controls. The thalamus, corpus striatum, hippocampus, amygdala, brainstem, callosum and ventricles were segmented from brain MRIs. To investigate subcortical shape, we analyzed the Jacobian determinant (JD) and radial distances (RD) for structure surfaces. We also investigated effects of nadir CD4+ T-cell counts, viral load, and illness duration on subcortical morphology. Our results characterize subcortical morphometry in older HIV+ people, where participants showed significant volumetric enlargements in the thalamus, left pallidum and the ventricles while showing a reduction in the callosum. Further, RD maps revealed atrophy of the left thalamus and expansion of the brainstem in HIV. RD and JD maps of the right pallidum identified tissue expansion associated with illness duration while the left pallidum showed anterior atrophy and posterior expansion associated with viral load. © 2015 IEEE.

关键词： Expansion

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User research for the instructional module development (IMODTM) system

User research for the instructional module development (IMOD...

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121st ASEE Annual Conference and Exposition: 360 Degrees of engineering Education

作者： Dalrymple, Odesma Onika Bansal, Srividya Kona Gaffar, Ashraf Dept. of Engineering and Computing Systems Polytechnic campus Arizona State University United States

A team of researchers from Arizona State University is engaging in a User-Centered Design (UCD) approach to develop the Instructional Module Development System (IMODTM), i.e., a software program that facilitates course design. The IMODTM system will be an open-source web-based tool that will guide individual or collaborating STEM educators, step-by-step, through an outcome-based education process as they define learning objectives, select content to be covered, develop an instruction and assessment plan, and define the learning environment and context for their course(s). It will also contain a repository of current best pedagogical and assessment practices, and based on selections the user makes when defining the learning objectives of the course, the IMODTM system will present options for assessment and instruction that aligns with the type/level of student learning desired. While one of the key deliverables of the project is the software tool, the primary focus of this initiative is to advance the development of faculty expertise in course design for undergraduate STEM education. To this end, the project addresses the following two research goals: 1. Identify deficiencies in user interactions with existing course design tools. 2. Obtain consensus opinion on a representation of the required knowledge (learning taxonomies, help data and pedagogical and assessment strategies) for designing a course or learning environment. In this paper we present a project update and the data collected so far from user studies that have been conducted. © American Society for engineering Education, 2014.

关键词： Open source software

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RFA-Cut: Semi-automatic Segmentation of Radiofrequency Ablation Zones with and without Needles via Optimal s-t-Cuts

RFA-Cut: Semi-automatic Segmentation of Radiofrequency Ablat...

引用

Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Jan Egger Harald Busse Philipp Brandmaier Daniel Seider Matthias Gawlitza Steffen Strocka Philip Voglreiter Mark Dokter Michael Hofmann Bernhard Kainz Xiaojun Chen Alexander Hann Pedro Boechat Wei Yu Bernd Freisleben Tuomas Alhonnoro Mika Pollari Michael Moche Dieter Schmalstieg Institute for Computer Graphics and Vision Graz University of Technology Austria Dept. of Diagnostic and Interventional Radiology Leipzig University Hospital Germany Dept. of Computing Imperial College London UK School of Mechanical Engineering Shanghai Jiao Tong University Shanghai China Dept. of Internal Medicine and Gastroenterology Katharinenhospital Stuttgart Germany Distributed Systems Group Philipp University of Marburg Germany School of Science Aalto University Espoo Finland

ISBN: (纸本)9781424492695

In this contribution, we present a semi-automatic segmentation algorithm for radiofrequency ablation (RFA) zones via optimal s-t-cuts. Our interactive graph-based approach builds upon a polyhedron to construct the graph and was specifically designed for computed tomography (CT) acquisitions from patients that had RFA treatments of Hepatocellular Carcinomas (HCC). For evaluation, we used twelve post-interventional CT datasets from the clinical routine and as evaluation metric we utilized the Dice Similarity Coefficient (DSC), which is commonly accepted for judging computer aided medical segmentation tasks. Compared with pure manual slice-by-slice expert segmentations from interventional radiologists, we were able to achieve a DSC of about eighty percent, which is sufficient for our clinical needs. Moreover, our approach was able to handle images containing (DSC=75.9%) and not containing (78.1%) the RFA needles still in place. Additionally, we found no statistically significant difference (p<0.423) between the segmentation results of the subgroups for a Mann-Whitney test. Finally, to the best of our knowledge, this is the first time a segmentation approach for CT scans including the RFA needles is reported and we show why another state-of-the-art segmentation method fails for these cases. Intraoperative scans including an RFA probe are very critical in the clinical practice and need a very careful segmentation and inspection to avoid under-treatment, which may result in tumor recurrence (up to 40%). If the decision can be made during the intervention, an additional ablation can be performed without removing the entire needle. This decreases the patient stress and associated risks and costs of a separate intervention at a later date. Ultimately, the segmented ablation zone containing the RFA needle can be used for a precise ablation simulation as the real needle position is known.

关键词： RFA decreases patient stress

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Warp-level divergence in GPUs: Characterization, impact, and mitigation

Warp-level divergence in GPUs: Characterization, impact, and...

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20th IEEE International Symposium on High Performance Computer Architecture, HPCA 2014

作者： Xiang, Ping Yang, Yi Zhou, Huiyang Dept. of Electrical and Computer Engineering North Carolina State University Raleigh NC United States Dept. of Computing Systems Architecture NEC Laboratories America Princeton NJ United States

ISBN: (纸本)9781479930975

High throughput architectures rely on high thread-level parallelism (TLP) to hide execution latencies. In state-of-art graphics processing units (GPUs), threads are organized in a grid of thread blocks (TBs) and each TB contains tens to hundreds of threads. With a TB-level resource management scheme, all the resource required by a TB is allocated/released when it is dispatched to / finished in a streaming multiprocessor (SM). In this paper, we highlight that such TB-level resource management can severely affect the TLP that may be achieved in the hardware. First, different warps in a TB may finish at different times, which we refer to as 'warp-level divergence'. Due to TB-level resource management, the resources allocated to early finished warps are essentially wasted as they need to wait for the longest running warp in the same TB to finish. Second, TB-level management can lead to resource fragmentation. For example, the maximum number of threads to run on an SM in an NVIDIA GTX 480 GPU is 1536. For an application with a TB containing 1024 threads, only 1 TB can run on the SM even though it has sufficient resource for a few hundreds more threads. To overcome these inefficiencies, we propose to allocate and release resources at the warp level. Warps are dispatched to an SM as long as it has sufficient resource for a warp rather than a TB. Furthermore, whenever a warp is completed, its resource is released and can accommodate a new warp. This way, we effectively increase the number of active warps without actually increasing the size of critical resources. We present our lightweight architectural support for our proposed warp-level resource management. The experimental results show that our approach achieves up to 76.0% and an average of 16.0% performance gains and up to 21.7% and an average of 6.7% energy savings at minor hardware overhead. © 2014 IEEE.

关键词： Graphics processing unit

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Mapping abnormal subcortical brain morphometry in an elderly HIV+ cohort

Mapping abnormal subcortical brain morphometry in an elderly...

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IEEE International Symposium on Biomedical Imaging

作者： Benjamin S. C. Wade Victor G. Valcour Lauren Wendelken-Riegelhaupt Pardis Esmaeili-Firidouni Shantanu H. Joshi Yalin Wang Paul M. Thompson Imaging Genetics Center University of Southern California Los Angeles CA USA Dept. of Neurology University of California San Francisco CA USA Department of Neurology UCLA CA USA School of Computing Informatics and Decisio Systems Engineering Arizona State University Tempe AZ USA

ISBN: (纸本)9781467393300

关键词： Human immunodeficiency virus Surface morphology Atrophy Radio frequency Shape Three-dimensional displays Magnetic resonance imaging

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Biologically inspired hierarchical model for traffic sign recognition 24

Biologically inspired hierarchical model for traffic sign re...

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24th International Conference on Computer Theory and Applications, ICCTA 2014

作者： Aziz, Amr Abdel Imam, Ibrahim F. Shoukry, Amin College of Computing and Information Technology Arab Academy for Science Technology and Maritime Transport Cairo Egypt Computer and Systems Engineering Dept. Faculty of Engineering Alexandria University Alexandria Egypt

ISBN: (纸本)9781479974757

In this research, a study of the Hierarchical Temporal Memory (HTM) model using the Numenta Implementation 'Nupic v1.7' and an investigation of its performance in solving the German traffic sign recognition task using standard benchmark data is conducted. Its performance is compared to that of a state of the art Multi-Column Deep Neural Network (MCDNN) that has been proved to exceed the human recognition accuracy for the same task. © 2014 IEEE.

关键词： Image classification

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Haptic intelligent interfaces for NAO robot hand control

Haptic intelligent interfaces for NAO robot hand control

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International Conference on Advanced Mechatronic systems (ICAMechS)

作者： Octavian Melinte Luige Vladareanu Ligia Munteanu Hongnian Yu Shuang Cang Zeng-Guang Hou Gui-Bin Bian Hongbo Wang Dept. Robotics and Mechatronics Institute of Solid Mechanics of Romanian Academy Bucharest Romania Engineering and Computing Bournemouth University Dorset UK State Key Laboratory of Management and Control for Complex Systems Chinese Academy of Sciences Beijing China Parallel Robot and Mechatronic Sys. Lab. Yanshan University Qinhuangdao China

The paper presents a new approach on haptic interface control for NAO robotic hand. The haptic teleoperation of NAO robot hand raises some issues, mapping the haptic device dynamic being the most important. The mapping was achieved through Neural Network by determining a dynamic gain of robot haptic feedback. The results lead to the achievement of the haptic intelligent interfaces for the NAO robot hand control which can be integrated into an innovative haptic robot control system.

关键词： Decision support systems Humanoid robots Haptic interfaces Economic indicators Joints Mechatronics

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A personalized quiz game based on multi-agent system

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2012 International Workshops on Web-Based Learning, ICWL 2012 - KMEL, SciLearn, and CCSTED

作者： Weng, Martin M. Hung, Jason C. Lin, Fuhua Shih, Timothy K. Dept. of Computer Science and Information Engineering Tamkang University China Department of Information Management Overseas Chinese University China School of Computing and Information Systems Athabasca University Alberta Canada Dept. of Computer Science and Information Engineering National Central University China

ISBN: (纸本)9783662434536

The intelligent agent based systems have existed for many years, only recently its surge of mainstream popularity motivated researchers to acknowledge its educational value. With the increasing usage of educational games, using intelligent agents in the game to provide reliable personalized services has become more critical. Quiz game is a game genre which is easy to develop and doesn't have limitation to any subject and user group. Multi-agent based system is flexible and can save resource. This research designs a quiz game based on multi-agent architecture, the game is therefore so-called multi-agent based Quiz-MASter. Beside the quiz game, this paper also presents a framework of personalized assessment game. With the Quiz-MASter and the framework, the instructors can aware of students' playing status and experiences while the students playing the game and don't feel that they are taking exam/quiz at all. © 2014 Springer-Verlag.

关键词： Intelligent agents

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Curriculum exchange: Teaching energy concepts using chain reaction machines

Curriculum exchange: Teaching energy concepts using chain re...

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121st ASEE Annual Conference and Exposition: 360 Degrees of engineering Education

作者： McCall, Shakira Renee Dalrymple, Odesma Onika Jordan, Shawn S. Polytechnic Campus Arizona State University United States Dept. of Engineering and Computing Systems Polytechnic Campus Arizona State University United States Department of Engineering Polytechnic Campus Arizona State University United States

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Direction of arrival estimation of wideband signals using sub-Nyquist samples

Direction of arrival estimation of wideband signals using su...

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Sensor Array and Multichannel Signal Processing Workshop

作者： Amal Chaturvedi H. Howard Fan Dept. of Electrical Engineering and Computing Systems University of Cincinnati Cincinnati Ohio

This work is dedicated towards finding the Direction of Arrival (DOA) of Wideband signals using Sub-Nyquist samples. In a sensor array, the time delay between two sensors depends on the position of sources and thus its estimate could be used in finding the DOA of the sources. In this paper, we propose to estimate the time delay among sensors using cross-correlation of the signals received at the sensor array. The wider the bandwidth of the signal, the sharper will be the peak of its autocorrelation. Thus, it would be safe to assume that the autocorrelation of a wideband signal is sparse. The number of sharp peaks in the autocorrelation will be the same as the number of uncorrelated sources. The strength of Compressive Sampling (CS) lies in solving an underdetermined problem with a very high probability, provided the solution is sparse. This fits our wideband DOA problem very well, and is used to estimate the autocorrelation and hence the DOA of the signals with sub-Nyquist sampling. Simulations are given to support this concept.

关键词： Direction-of-arrival estimation Correlation Wideband Arrays Estimation Delay effects

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