Humans have needs motivating their behavior according to intensity and context. However, we also create preferences associated with each action’s perceived pleasure, which is susceptible to changes over time. This ma...
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We implemented MDI-QKD with a novel polarization compensation scheme using discarded bits without reducing the key-sharing cycle or demanding additional resources. Polarization drift was maintained below 0.13 rad over...
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The increasing demands on throughput and accuracy of semiconductor manufacturing equipment necessitates accurate feedforward motion control that includes compensation of input nonlinearities. The aim of this paper is ...
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The increasing demands on throughput and accuracy of semiconductor manufacturing equipment necessitates accurate feedforward motion control that includes compensation of input nonlinearities. The aim of this paper is to develop a data-driven feedforward approach consisting of a Wiener feedforward, i.e., linear parameterization with an output nonlinearity, to achieve high tracking accuracy and task flexibility for a class of Hammerstein systems. The developed approach exploits iterative learning control to learn a feedforward signal from data that minimizes the error and utilizes a control-relevant cost function to learn the parameters of a Wiener feedforward parameterization. Experimental validation on a wirebonder shows that the developed approach enables high tracking accuracy and task flexibility.
Recent innovations and developments in molecular biology and biotechnology have made it possible to acquire and store large omics datasets. In particular genomics, transcriptomics and the study of their relationship r...
Recent innovations and developments in molecular biology and biotechnology have made it possible to acquire and store large omics datasets. In particular genomics, transcriptomics and the study of their relationship represent the key elements to understand how genotype influences phenotype. In this work we investigate the potential of multi-layer network modeling in integrating genomic and transcriptomic data of 152 advanced non-small cell lung cancer (NSCLC) patients treated with anti-PD-(L)1 therapy. For the transcriptomic layer, we performed differential expression and differential co-expression analyses in order to identify a subset of key genes in differentiating responder patients from non-responders. Adding to the genomic-transcriptomic model other three layers related to immune, myeloid and curated immunotherapy-based literature signatures we obtained a 5-layer Patient Similarity Network. The application of Similarity Network Fusion algorithm revealed a statistically significant stratification of patients (p-value ≤ 0.05) which allows the identification of two clusters characterized by patients responding and not responding to immunotherapy.
Mixed-precision neural network (MPNN) that utilizes just enough data width for the neural network processing is an effective approach to meet the stringent resources constraints including memory and computing of MCUs....
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A low cost, open source, rugged, modular OpenPLC, based on ATmega16 microcontroller, has been developed for instructional purposes. Modularity permits flexible use of the OpenPLC. The open source software LDmicro, cre...
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ISBN:
(纸本)9781665490498
A low cost, open source, rugged, modular OpenPLC, based on ATmega16 microcontroller, has been developed for instructional purposes. Modularity permits flexible use of the OpenPLC. The open source software LDmicro, created for ladder logic operations, has been enhanced, and ported to Linux. A total of 27 Spoken Tutorials of about 10 minute duration each, suitable for self learning, are created for OpenPLC training. A pilot workshop is conducted for 16 teachers of polytechnic colleges using the Spoken Tutorials and the simulation capability of LDmicro. The feedback from the workshop is positive, and the method is suitable for a large scale training.
Dual-arm manipulation is a key enabler for significantly enhancing the interaction between humans and robots, and their capabilities to purposefully shape the surrounding environment. However, the spatiotemporal coord...
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ISBN:
(数字)9798331509231
ISBN:
(纸本)9798331509248
Dual-arm manipulation is a key enabler for significantly enhancing the interaction between humans and robots, and their capabilities to purposefully shape the surrounding environment. However, the spatiotemporal coordination between the motion of the hands required for this type of actions makes their planning not trivial. A proper definition of these coordination patterns moving from the human example could simplify their translation on the robot side, fostering the generation of effective bimanual tasks. In this work, we propose Multivariate functional Principal Component Analysis (MfPCA) as a mathematical tool to encode inter-hands temporal kinematic covariations in terms of principal spatiotemporal coordination patterns in the Cartesian domain. We compared these patterns extracted from a dataset of human bimanual tasks with those resulting from the usage of classical fPCA, applied independently to each hand (univariate fPCA). We found that MfPCA allows for a better classification of the tasks, with respect to a state of the art taxonomy. For what concerns motion planning, MfPCA and fPCA yield similar accuracy in the reconstruction of the motion, but with a smaller number of principal components needed in the MfPCA case. These results, although preliminary, can open interesting perspectives for the usage of MfPCA for human-like bimanual motion planning and control of robotic manipulators, as well as for action recognition, to enable a more effective human-robot interaction.
The problem of non-collocated vibration absorption is targeted utilizing a multiparameter delay-based controller. The combined objective is to achieve closed-loop stability and vibration suppression at a target locati...
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The problem of non-collocated vibration absorption is targeted utilizing a multiparameter delay-based controller. The combined objective is to achieve closed-loop stability and vibration suppression at a target location, which is different from the position of the absorber. This problem can be translated into an optimization problem of shaping the poles of a closed-loop system with delays subject to zero-location constraints. The solution approach involves remodelling the closed-loop system as a system of delay-differential algebraic equations (DDAEs) which allows to systematically account for delays in the control law, thereby enabling a straightforward technique for computation of controller parameters. Finally, the proposed design method is validated by simulation on a lumped parameter model of a mass-spring-damper system.
It is well known that Drug Design is often a costly process both in terms of time and economic effort. While good Quantitative Structure-Activity Relationship models (QSAR) can help predicting molecular properties wit...
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Since the introduction of artificial intelligence in medicinal chemistry, the necessity has emerged to analyse how molecular property variation is modulated by either single atoms or chemical groups. In this paper, we...
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