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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Min Kyung Kwon Ki Chang Nam Da Som Lee Kyung Hwan Jang Deok Won Kim Brain Korea 21 Project for Medical Science Yonsei University Dept. of Medical Engineering Yonsei University College of Medicine Graduate Program in Biomedical Engineering Yonsei University

ISBN: (纸本)9781424441211

This paper describes an experimental setup for evaluating the physiological effects of radiofrequency (RF) emitted from a Wideband Code Division Multiple Access (WCDMA) module with a 24 dBm at 1950 MHz for specific absorption rate (SAR_(1g)) of 1.57 W/kg. This provocation study was executed in a double-blind study of two volunteer groups of 10 self-reported electromagnetic hypersensitivity (EHS) and 10 non-EHS subjects under both sham and real exposures in a randomly assigned and counter-balanced order. In the preliminary results, WCDMA RF exposure of 30 min did not have any effects on physiological changes in either group.

关键词： Smartphone WCDMA radiofrequency Double-Blind Method anti-balance Placebos code division Specific absorption rate

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Training oscillatory dynamics with spike-timing-dependent plasticity in a computer model of neocortex

Training oscillatory dynamics with spike-timing-dependent pl...

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IEEE Signal Processing in Medicine and Biology Symposium (SPMB)

作者： Samuel A Neymotin Cliff C Kerr Joseph T Francis William W Lytton Biomedical Engineering Program SUNY Downstate 1 NYU-Poly Brooklyn New York USA Dept. Physics U. Sydney Sydney Australia Dept. Physiology & Pharmacology SUNY Downstate Medical Center Brooklyn NY Dept. Physiology & Pharmacology SUNY Downstate Medical Center Brooklyn NY USA Dept. Neurology Kings County Hospital Center Brooklyn NY USA

Neuronal networks are complex, adaptive systems that typically display oscillatory dynamics. The extent to which these dynamics can be shaped by training remains unknown. We explored this dynamical training in a computer model of 6-layered sensory neocortex with 470 excitatory (E) and inhibitory (I) cells. AMPA, NMDA, and GABAA synapses were provided with Poisson input to provide baseline activation in the network. The learning rule employed spike-timing-dependent plasticity (STDP) at all AMPA synapses. We trained with a 1-16 Hz thalamic afferent signal to E4 cells (layer 4 E cells). At baseline, the power spectrum of the network activity showed oscillations with a low-amplitude peak near 6 Hz. Plasticity in the absence of a training signal (white noise input) attenuated the network response, due to the potentiation of E-to-I synapses. Plasticity coupled with an 8 Hz training signal enhanced the network's oscillations and shifted the peak to ~20 Hz. This was due to increased synaptic connection strengths between E cells caused by the near-synchronous firing of E4 cells. Plasticity coupled with a 16 Hz training signal shifted the network towards epilepsy, with high-amplitude 8 Hz oscillations and synchronous firing across all layers. The shift into epilepsy was caused by further enhancement of E-to-E synapses. In summary, our simulations demonstrate the feasibility of using plasticity and neuroprosthetic input signals to train a neuronal network's oscillatory dynamics. We predict that in order for learning in the brain to avoid transition to epilepsy, homeostatic control mechanisms must balance learning at E-to-E and E-to-I synapses.

关键词： Training Neurons

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Optical redox imaging of endogenous contrast for tissue-engineered construct viability

Optical redox imaging of endogenous contrast for tissue-engi...

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Optical Molecular Probes, Imaging and Drug Delivery, OMP 2011

作者： Chen, Leng-Chun Lloyd, William R. Chandra, Malavika Izumi, Kenji Kuo, Shiuhyang Marcelo, Cynthia L. Feinberg, Stephen E. Mycek, Mary-Ann Dept. of Biomedical Engineering Ann Arbor MI 48109-2099 United States Applied Physics Program Ann Arbor MI 48109-2099 United States Oral and Maxillofacial Surgery Ann Arbor MI 48109-2099 United States Plastic Surgery University of Michigan Ann Arbor MI 48109-2099 United States Niigata University Division of Oral Anatomy Niigata-city Niigata 951-8514 Japan

Endogenous fluorescence redox imaging was developed to noninvasively assess cell viability in 3-dimensional tissue-engineered constructs prior to implantation. A lower redox ratio was observed from samples with higher... 详细信息

ISBN: (纸本)9781557529091

关键词： Controlled drug delivery

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Dynamic Brain-Machine Interface: a novel paradigm for bidirectional interaction between brains and dynamical systems

Dynamic Brain-Machine Interface: a novel paradigm for bidire...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Francois D. Szymanski Marianna Semprini Ferdinando A. Mussa-Ivaldi Luciano Fadiga Stefano Panzeri Alessandro Vato Robotics Brain and Cognitive Sciences Dept. Istituto Italiano di Tecnologia Physical Medicine & Rehabilitation Mechanical and Biomedical Engineering at Northwestern University and Sensory Motor Performance Program Rehabilitation Institute of Chicago Section of Human Physiology University of Ferrara

ISBN: (纸本)9781424441211

Brain-Machine Interfaces (BMIs) are systems which mediate communication between brains and artificial devices. Their long term goal is to restore motor functions, and this ultimately demands the development of a new generation of bidirectional brain-machine interfaces establishing a two-way brain-world communication channel, by both decoding motor commands from neural activity and providing feedback to the brain by electrical stimulation. Taking inspiration from how the spinal cord of vertebrates mediates communication between the brain and the limbs, here we present a model of a bidirectional brain-machine interface that interacts with a dynamical system by generating a control policy in the form of a force field. In our model, bidirectional communication takes place via two elements: (a) a motor interface decoding activities recorded from a motor cortical area, and (b) a sensory interface encoding the state of the controlled device into electrical stimuli delivered to a somatosensory area. We propose a specific mathematical model of the sensory and motor interfaces guiding a point mass moving in a viscous medium, and we demonstrate its performance by testing it on realistically simulated neural responses.

关键词： Cerebrum DYNAMICAL SYSTEMS Bidirectional viscous medium Diencephalon control strategy Communication Research Motor Sensation Mathematical Model DECODING field theory (physics)

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Abstracts Of Shellfish Technical Papers Presented at the joint meeting of the Northeast Aquaculture Conference and Exposition Milford Aquaculture Seminar and the International Conference on Shellfish Restoration Groton, Connecticut December 12–15, 2012

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Journal of Shellfish Research 2013年第2期32卷 571-612页

作者： Walter Blogoslawski Christopher Davis Dorothy Leonard Lisa Milke Steven Allen Peter Bergstrom A.C. Carpenter Mark Luckenbach Kennedy Paynter Angela Sowers Eric Weissberger James Wesson Stephanie Westby Steven Allen Stephanie Westby Claire O'Neil Angela Sowers Eric Weisberrger Oliver Bender Peter Boyce Gabriel Betty Mark Borrelli Anamarija Frankic Curtis Felix Jennifer Wilson Peter Boyce Oliver Bender Suzanne Bricker Tessa Getchis Cary Chadwick Julie Rose Cori Rose Kelsey Brockett Jessica Peterman David Bushek Daphne Munroe Eric Powell Lisa Calvo Barney Hollinger William Riggin William Shadel Jenny Paterno Ryan Carnegie David Bushek Carole Cyr Lisandre G. Solomon Francoise Bourque Tyler Carrier Stephen Eddy Sarah Redmond James Cervino Rand Weeks Jason Shorr Carmen Lin Dajana Gjoza Thomas J. Goreau Erik Chapman Derrick Chelikowsky Diane Kapareiko Dorothy Jefferess Gary Wikfors Carmela Cuomo Joseph Choromanski Sheila Stiles Dorothy Jeffress Haley Ladeau Loren Coen Boze Hancock Lesley Baggett Sean Powers Rob Brumbaugh Summer Morlock Bryan DeAngelis Anne Cohen Daniel McCorkle Gail Schwietermann Kathryn Rose Dave Conley SaiGiridhar Dasika April Croxton Soren Dahl Debra Barnes Bassem Allam Jonathan Davis Brian Allen Betsy Peabody Jonathan Davis Julie Davis William Walton Donatella Del Piero Michael Devin Molly Flanagan Paul Rawson Chauncey Devin Dana Morse Mark S. Dixon Genevieve Bernatchez Kelsey Boeff Eve Galimany Yaqin Li Aynur Lok Shannon L. Meseck Marguerite Petit Sean Dixon Sam Lee Dennis O'Connor Kelly Drake Shelley Edmundson Elizabeth Fairchild Melissa Evans Allison Fitzgerald Chester Zarnoch William Wallace Amy Fitzpatrick Gef Flimlin Sandra Macfarlane Gef Flimlin Thomas Foca David Bushek Timothy Visel Walter Blogoslawski Deborah A. Bouchard Joseph Buttner John Ewart Ann Faulds George E. Flimlin Doris Hicks Craig Hollingsworth Andrew Lazur Dale Leavitt Dennis McIntosh Dana L. Morse Tom Rippen Gregg Rivara Roxanna Smolowitz Dan Terlizzi Don Webster Michael Chambers Diane C. Murphy Robert Pomeroy Josh Reitsma Mic U.S. Department of Commerce National Oceanic and Atmospheric Administration National Marine Fisheries Service Northeast Fisheries Science Center Milford Laboratory 212 Rogers Avenue Milford CT 06460 Maine Aquaculture Innovation Center 5717 Corbett Hall Room 436 Orono ME 04469 Ocean Equities LLC 776 Rolling View Drive Annapolis MD 21409. Oyster Recovery Partnership 1805A Virginia St Annapolis MD 21401 NOAA Chesapeake Bay Office 410 Severn Ave Suite 207-A Annapolis MD 21403 Potomac River Fisheries Commission 222 Taylor St Colonial Beach VA 22443 Virginia Institute of Marine Science Eastern Shore Laboratory PO Box 350 Wachapreague VA 23480 1213 HJ Patterson Hall University of Maryland College Park MD 20742 U. S. Army Corps of Engineers Baltimore District P.O. Box 1715 Baltimore MD 21203 Maryland Department of Natural Resources 580 Taylor Ave Annapolis MD 21401 Virginia Marine Resources Commission 2600 Washington Ave Newport News VA 23607 NOAA Restoration Center 410 Severn Ave Annapolis MD 21403. Oyster Recovery Partnership 1805A Virginia St Annpolis MD 21401 National Oceanographic and Atmospheric Administration 410 Severn Ave Suite 107-A Annapolis MD 21403 USA Army Corps of Engineers 10 South Howard St Baltimore MD 21201 Maryland Department of Natural Resources 580 Taylor Ave Tawes State Office Building Annapolis MD 21401. Maria Mitchell Association 4 Vestal St Nantucket MA 02554 Maria Mitchell Association 65 Meadowview Drive Nantucket MA 02554. University of Rhode Island 620 Main St. Hopkinton RI 02832. Provincetown Center for Coastal Studies 5 Holway Avenue Provincetown MA 02657 University of Massachusetts Boston 100 Morrissey Blvd Boston Massachusetts Boston MA Town of Wellfleet 300 Main Street Wellfleet Massachusetts MA 02667. Maria Mitchell Association 65 Meadowview Dr Nantucket MA 02554. NOAA National Center for Coastal Ocean Science 1305 East West Highway Room 8110 Silver Spring MD 20910 Connecticut Sea Grant University o

It was with great excitement that we planned the combined meetings of Northeast Aquaculture Conference and Exposition (NACE) and the International Conference on Shellfish Restoration (ICSR) with the 33rd Milford Aquaculture Seminar (MAS). Bringing these different but complementary audiences together resulted in a meeting that combined many different aspects of fisheries restoration and aquaculture under one *** hundred attendees including government representatives, research scientists, industry, and academia at both the university and vocational high school levels attended this event. The meeting commenced on Wednesday December 12th 2012, with over eighty people attending seven field trips to area aquaculture farms and research facilities. The formal program began on Thursday, December 13th with a plenary session including invited speakers Eric Schwabb, Acting Assistant Secretary for Conservation and Management at NOAA; Sebastian Belle, Executive Director of the Maine Aquaculture Association and Boze Hancock from the Nature Conservancy, who discussed the role of aquaculture in fisheries restoration. John Bullard, the Northeast Regional Administrator of NOAA Fisheries Service, addressed the group during the luncheon the following day. The technical papers and workshops presented were divided into 35 sessions over three days of the meeting and included topics such as the history of aquaculture, aquaculture hatchery innovations, siting and planning issues, risk management, aquaculture business management, ocean acidification, climate change, as well as aquaculture disease issues and potential remedies. Having persons present who have experienced problems and successes, along with those in manufacturing and government responsible for addressing concerns and sharing best practices, was invaluable. Discussions among this cross-section of persons who represent different aspects of aquaculture were as important as the well-presented and interesting formal papers

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Temperature dependence of liquid crystal molecular on dye-sensitized solar cells

Temperature dependence of liquid crystal molecular on dye-se...

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作者： Kang, Wan-Seok Hur, Seung-Yeol Jin, Sung-Ho Lee, Gi-Dong Dept. of Electronics Engineering Dong-A University Busan 604-714 Korea Republic of Dept. of Chemistry Education Interdisciplinary Program of Advanced Information and Display Materials Pusan National University Busan 609-735 Korea Republic of

ISBN: (纸本)9781617827020

We confirmed that liquid crystal (LC) molecules enhanced the power-conversion efficiency (PEC) in a quasi solid-state dye-sensitized solar cell (DSSC). The scalar order parameter of nematic LC is 0.5-0.7 at room temperature. This implies that most of the LC molecules are aligned in the similar direction to one another. We fabricated a quasi solid-state DSSC which contained nematic LC or not and measured the PEC, Jsc, and V oc changing a temperature. From the experimental results, we proved that ordering of nematic LC increase the efficiency of a DSSC in a quasi-solid state DSSC.

关键词： Dye-sensitized solar cells

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Altered information transfer in neuronal networks marks pathology

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BMC Neuroscience 2010年第1期11卷 1-2页

作者： Samuel A Neymotin Heekyung Lee Eunhye Park Andre A Fenton William W Lytton SUNY Downstate/Polytechnic Joint Biomedical Engineering Program Brooklyn NY 11203 USA Neural and Behavioral Sciences Program SUNY Downstate USA Dept. Physiology & Pharmacology SUNY Downstate USA Center for Neural Science New York University New York NY 10003 USA Neurology SUNY Downstate USA Biomedical Engineering Brooklyn NY 11203 USA

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Harmonic golay coded excitation using mutually orthogonal golay codes and pulse inversion

Harmonic golay coded excitation using mutually orthogonal go...

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Medical Imaging 2009: Ultrasonic Imaging and Signal Processing

作者： Kim, Sang-Min Song, Jae-Hee Song, Tai-Kyong Dept. of Electronic Engineering Sogang University Seoul Korea Republic of Interdisciplinary Program in Biofusion Technology Seoul Korea Republic of

ISBN: (纸本)9780819475169

Coded excitation can improve the performance factors, such as SNR and CTR, of harmonic imaging with a low voltage transmit waveform. For these purposes, harmonic imaging methods using Golay codes with advantages in range sidelobe levels and implementation simplicity have been proposed. However, they require four transmit-receive (T/R) events to form each scan line. This work describes a new harmonic Golay coded excitation technique to overcome this problem. The proposed method can produce two scan lines through four T/R events using four pairs of codes. On the first T/R cycle, the first pair of codes is fired sequentially, one at a time, along each of the two scan lines, where the two codes are designed such that their second harmonic components are mutually orthogonal Golay codes. The same transmit sequence is carried out with the second pair of codes, each of which being 180 degrees out of phase with the corresponding one of the first pair of codes to remove the fundamental components by simply adding the two resulting received signals. The third and fourth T/R cycles are followed in the same manner, but with the codes whose harmonic components are composed of the complementary set of the mutually orthogonal Golay codes used in the first T/R cycle and their sign inverted codes, respectively. Consequently, the mutually orthogonal Golay codes and their complementary set of codes representing only the harmonic components are obtained after four T/R events. Finally, using the orthogonal and complementary properties, the coded harmonic signals along each scan line can easily be separated and compressed. Computer simulation results show that the proposed method can successfully perform pulse-inversion harmonic imaging to produce two scan lines simultaneously after four T/R events with coded sequences. © 2009 SPIE.

关键词： Harmonic analysis

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Development of a portable A-ABR screener using a microprocessor

Development of a portable A-ABR screener using a microproces...

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31st Annual International Conference of the IEEE engineering in Medicine and Biology Society: engineering the Future of Biomedicine, EMBC 2009

作者： Noh, Hyung Wook Lee, Tak Hyung Kim, Jong Wook Yang, Dong In Cha, Eun Jong Kim, Deok Won Graduate Program in Biomedical Engineering Yonsei University Seoul Korea Republic of Dept. of Biomedical Engineering College of Medicine Chungbuk National University Chungbuk Korea Republic of Dept. of Medical Engineering College of Medicine Yonsei University Seoul Korea Republic of

ISBN: (纸本)9781424432967

Hearing loss is one of the most common birth defects among infants. Most hearing-impaired children are not diagnosed until one to three years of age, which is too late to treat for normal speech and language development. If hearing impairment is identified and treated in its early stage, a child's speech and language skills could be comparable to his or her normal-hearing peers. Auditory brain-stem response (ABR) is nowadays one of the most reliable diagnostic tools in the early detection of hearing impairment. In this study, we applied the 'Fsp' method to distinguish between normal and impaired hearing. We have developed a battery-operated portable automated auditory brainstem response (A-ABR) system that automatically detects hearing impairment in neonates or infants. We partially validated the accuracy of this system in twenty normal-hearing adults. ©2009 IEEE.

关键词： Brain

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Reconstruction algorithms for interior and exterior spherical radon transform-based ultrasound imaging

Reconstruction algorithms for interior and exterior spherica...

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Medical Imaging 2009: Ultrasonic Imaging and Signal Processing

作者： Vaidyanathan, Ravi Shankar Lewis, Matthew A. Ambartsoumian, Gaik Aktosun, Tuncay Graduate Program in Biomedical Engineering UTSouthwestern Medical Center United States Dept. of Mathematics UT Arlington United States

ISBN: (纸本)9780819475169

This work is concerned with the numerical implementation of a reconstruction algorithm developed to recover a function from its spherical means over spheres centered on a circle. The algorithm is experimentally verified by simulations using numerical phantoms. In the scheme of tomography, acoustic waves are generated by illuminating an object with a short burst of radio-frequency waves. In applications, like breast cancer imaging, which use modalities like photo-acoustic tomography (PAT) that model the acoustic pressures as spherical means, data are measured on the detectors located in a circle surrounding the object. This is then used to reconstruct the absorption density inside the object. In contrast, applications like bore hole tomography and improved Intravascular Ultra Sound (IVUS) imaging for prostate cancer, which use modalities like Radial Reflection Diffraction Tomography (RRDT), a ring of detectors placed exterior to the object, collect the acoustic waves as back-scattered field. This work uses a single algorithm to reconstruct functions from data collected using these two different techniques ? one, by placing the object inside the ring of detectors, and the other, by placing the object exterior to the ring of detectors. The algorithm then draws a comparison between the two reconstructions. The case of bistatic ultrasound imaging, where the elliptical Radon transform is appropriate, is also discussed. © 2009 SPIE.

关键词： Radon

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