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NuSegDG: Integration of heterogeneous space and Gaussian kernel for domain-generalized nuclei segmentation

Knowledge-Based systems 2025年 322卷

作者： Lou, Zhenye Xu, Qing Jiang, Zekun He, Xiangjian Li, Chenxin Chen, Zhen Wang, Yi He, Maggie M. Duan, Wenting Sichuan University Pittsburgh Institute Sichuan University Chengdu China School of Computer Science Computer Vision and Intellifent Perception Laboratory and Municipal Digital Port Technology Key Laboratory University of Nottingham Ningbo Zhejiang China West China Biomedical Big Data Center West China Hospital Sichuan University Chengdu China Hong Kong Institute of Science & Innovation Chinese Academy of Sciences Hong Kong School of Software Dalian University of Technology Dalian116600 China Department of Electronic Engineering The Chinese University of Hong Kong 999077 Hong Kong Department of Cardiology Gold Coast University Hospital QLD Australia School of Computer Science University of Lincoln LincolnLN6 7TS United Kingdom

Domain-generalized nuclei segmentation refers to the generalizability of models to unseen domains based on knowledge learned from source domains and is challenged by various image conditions, cell types, and stain strategies. Recently, the Segment Anything Model (SAM) has made great success in universal image segmentation by interactive prompt modes (e.g., point and box). Despite its strengths, the original SAM presents limited adaptation to medical images. Moreover, SAM requires providing manual bounding box prompts for each object to produce satisfactory segmentation masks, so it is laborious in nuclei segmentation scenarios. To address these limitations, we propose a domain-generalizable framework for nuclei image segmentation, abbreviated to NuSegDG. Specifically, we first devise a Heterogeneous Space Adapter (HS-Adapter) to learn multi-dimensional feature representations of different nuclei domains by injecting a small number of trainable parameters into the image encoder of SAM. To alleviate the labour-intensive requirement of manual prompts, we introduce a Gaussian-Kernel Prompt Encoder (GKP-Encoder) to generate density maps driven by a single point, which guides segmentation predictions by mixing position prompts and semantic prompts. Furthermore, we present a Two-Stage Mask Decoder (TSM-Decoder) to effectively convert semantic masks to instance maps without the manual demand for morphological shape refinement. Based on our experimental evaluations, the proposed NuSegDG demonstrates state-of-the-art performance in nuclei semantic and instance segmentation, exhibiting superior domain generalization capabilities. The source code is available at https://***/xq141839/NuSegDG. © 2025 Elsevier B.V.

关键词： Semantic Segmentation

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Surrogate-Model-Based Sequential Algorithm for Weather-Dependent Probabilistic Power Flow With High Calculation Efficiency

TechRxiv

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TechRxiv 2023年

作者： Zhang, Haochen Lin, Xingyu Peng, Sui Tang, Junjie Ponci, Ferdinanda Monti, Antonello Electrical and Computer Engineering Department University of California Los Angeles90095 United States State Key Laboratory of Power Transmission Equipment & System Security and New Technology Chongqing University Chongqing400044 China Grid Planning and Research Center Guangdong Power Grid Corporation CSG Guangzhou510080 China Institute for Automation of Complex Power Systems E.ON Energy Research Center RWTH Aachen University Aachen52074 Germany Digital Energy Fraunhofer FIT Aachen52072 Germany

Recently, a novel power flow model called weather dependent power flow (WDPF) has been proposed to incorporate conductor temperatures in power flow calculation. It is promising to adopt WDPF model in probabilistic analysis since it provides more accurate electrical and thermal states of a power system. However, calculation of the WDPF model is more computationally expensive than that of conventional power flow model, and hence repetitive calculation of the WDPF in probabilistic analysis is quite time-consuming. To overcome this challenge, a surrogate-model-based sequential algorithm is proposed for calculation of the WDPF model with high computational efficiency and good accuracy. Compared to the method that directly learns the whole WDPF model, the proposed method only learns the power flow sub-model whereas applies a linearization method to solve the thermal resistance sub-model. The construction of the proposed method considers the learning difficulty of the sub-model and the whole WDPF model, thus ensuring the high calculation accuracy. This study is the first to conduct a probabilistic power flow analysis based on the WDPF model. Numerical results in the IEEE 30-bus, 57-bus, and 118-bus systems demonstrate the importance of adopting the WDPF model in probabilistic analysis and the efficacy of the proposed method. © 2023, CC BY.

关键词： Linearization

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GSmooth: Certified Robustness against Semantic Transformations via Generalized Randomized Smoothing

arXiv

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arXiv 2022年

作者： Hao, Zhongkai Ying, Chengyang Dong, Yinpeng Su, Hang Song, Jian Zhu, Jun Department of Computer Science & Technology Institute for AI BNRist Center Tsinghua-Bosch Joint ML Center THBI Lab Tsinghua University China Department of Electronic Engineering Tsinghua University China RealAI China Peng Cheng Laboratory China Tsinghua University China Mobile Communications Group Co. Ltd. Joint Institute China Key Laboratory of Digital TV System of Guangdong Province and Shenzhen City Research Institute of Tsinghua University in Shenzhen China

Certified defenses such as randomized smoothing have shown promise towards building reliable machine learning systems against `p-norm bounded attacks. However, existing methods are insufficient or unable to provably defend against semantic transformations, especially those without closed-form expressions (such as defocus blur and pixelate), which are more common in practice and often unrestricted. To fill up this gap, we propose generalized randomized smoothing (GSmooth), a unified theoretical framework for certifying robustness against general semantic transformations via a novel dimension augmentation strategy. Under the GSmooth framework, we present a scalable algorithm that uses a surrogate image-to-image network to approximate the complex transformation. The surrogate model provides a powerful tool for studying the properties of semantic transformations and certifying robustness. Experimental results on several datasets demonstrate the effectiveness of our approach for robustness certification against multiple kinds of semantic transformations and corruptions, which is not achievable by the alternative baselines. Copyright © 2022, The Authors. All rights reserved.

关键词： Semantics

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Awareness in robotics: An early perspective from the viewpoint of the EIC Pathfinder Challenge "Awareness Inside"

arXiv

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arXiv 2024年

作者： Santina, Cosimo Della Corbato, Carlos Hernandez Sisman, Burak Leiva, Luis A. Arapakis, Ioannis Vakalellis, Michalis Vanderdonckt, Jean D’Haro, LuisFernando Manzi, Guido Becchio, Cristina Elamrani, Aïda Alirezaei, Mohsen Castellano, Ginevra Dimarogonas, Dimos V. Ghosh, Arabinda Haesaert, Sofie Soudjani, Sadegh Stroeve, Sybert Verschure, Paul Bacciu, Davide Deroy, Ophelia Bahrami, Bahador Gallicchio, Claudio Hauert, Sabine Sanz, Ricardo Lanillos, Pablo Iacca, Giovanni Sigg, Stephan Gasulla, Manel Steels, Luc Sierra, Carles Department of Cognitive Robotics Delft University of Technology Delft Netherlands Oberpfaffenhofen Germany Department of Computer Science University of Luxembourg Luxembourg 4 Telefónica I+D Spain AEGIS IT Research GmbH Germany Université catholique de Louvain Belgium Speech Technology and Machine Learning Group ETSI de Telecomunicación Universidad Politécnica de Madrid Madrid Spain Alien Venture Studio Alien Technology Transfer Rome Italy Hamburg Germany Institut Jean Nicod École Normale Supérieure Paris France Research Technology and Development Department Digital Industry Software Helmond Netherlands Department of Information Technology Uppsala University Uppsala Sweden Division of Decision and Control Systems School of Electrical Engineering and Computer Science KTH Royal Institute of Technology Stockholm Sweden Max Planck Institute for Software Systems Kaiserslautern Germany Department of Electrical Engineering Control Systems Group Eindhoven University of Technology Eindhoven Netherlands Amsterdam Netherlands Donders Centre for Neuroscience Radboud University Nijmegen Netherlands Computer Science Department University of Pisa Pisa Italy Faculty of Philosophy Philosophy of Science The Study of Religion Ludwig Maximilian University of Munich Munich Germany School of Engineering Mathematics and Technology University of Bristol Bristol United Kingdom Autonomous Systems Laboratory Universidad Politécnica de Madrid Spain Madrid Spain Department of Information Engineering and Computer Science University of Trento Trento Italy Department of Information and Communications Engineering Aalto University Espoo Finland Department of Electronic Engineering Universitat Politècnica de Catalunya Barcelona Spain Studio Stelluti Brussels Belgium Barcelona Spain

Consciousness has been historically a heavily debated topic in engineering, science, and philosophy. On the contrary, awareness had less success in raising the interest of scholars in the past. However, things are changing as more and more researchers are getting interested in answering questions concerning what awareness is and how it can be artificially generated. The landscape is rapidly evolving, with multiple voices and interpretations of the concept being conceived and techniques being developed. The goal of this paper is to summarize and discuss the ones among these voices that are connected with projects funded by the EIC Pathfinder Challenge called "Awareness Inside", a nonrecurring call for proposals within Horizon Europe that was designed specifically for fostering research on natural and synthetic awareness. In this perspective, we dedicate special attention to challenges and promises of applying synthetic awareness in robotics, as the development of mature techniques in this new field is expected to have a special impact on generating more capable and trustworthy embodied systems. © 2024, CC BY.

关键词： Robotics

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Intelligent Computing: The Latest Advances, Challenges and Future

arXiv

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arXiv 2022年

作者： Zhu, Shiqiang Yu, Ting Xu, Tao Chen, Hongyang Dustdar, Schahram Gigan, Sylvain Gunduz, Deniz Hossain, Ekram Jin, Yaochu Lin, Feng Liu, Bo Wan, Zhiguo Zhang, Ji Zhao, Zhifeng Zhu, Wentao Chen, Zuoning Durrani, Tariq S. Wang, Huaimin Wu, Jiangxing Zhang, Tongyi Pan, Yunhe Zhejiang Lab Hangzhou China TU Wien Austria Sorbonne University Paris France Department of Electrical and Electronic Engineering Imperial College London London United Kingdom Department of Electrical and Computer Engineering University of Manitoba Manitoba Canada Faculty of Technology Bielefeld University Bielefeld Germany Chinese Academy of Engineering Beijing China Department of Electronic and Electrical Engineering University of Strathclyde Glasgow United Kingdom National University of Defense Technology Changsha China National Digital Switching System Engineering & Technological R&D Center Zhengzhou China Materials Genome Institute Shanghai University Shanghai China Zhejiang University Hangzhou China

Computing is a critical driving force in the development of human civilization. In recent years, we have witnessed the emergence of intelligent computing, a new computing paradigm that is reshaping traditional computing and promoting digital revolution in the era of big data, artificial intelligence and internet-of-things with new computing theories, architectures, methods, systems, and applications. Intelligent computing has greatly broadened the scope of computing, extending it from traditional computing on data to increasingly diverse computing paradigms such as perceptual intelligence, cognitive intelligence, autonomous intelligence, and human-computer fusion intelligence. Intelligence and computing have undergone paths of different evolution and development for a long time but have become increasingly intertwined in recent years: intelligent computing is not only intelligence-oriented but also intelligence-driven. Such cross-fertilization has prompted the emergence and rapid advancement of intelligent computing. Intelligent computing is still in its infancy and an abundance of innovations in the theories, systems, and applications of intelligent computing are expected to occur soon. We present the first comprehensive survey of literature on intelligent computing, covering its theory fundamentals, the technological fusion of intelligence and computing, important applications, challenges, and future perspectives. We believe that this survey is highly timely and will provide a comprehensive reference and cast valuable insights into intelligent computing for academic and industrial researchers and practitioners. Copyright © 2022, The Authors. All rights reserved.

关键词： Surveys

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Dac-Pre: Practical Anonymous Data Access Scheme Control with Proxy Re-Encryption For Implantable Medical Devices

SSRN

引用

SSRN 2022年

作者： Kar, Jayaprakash Liu, Xiaoguang Li, Fagen Centre for Cryptography Cyber Security and Digital Forensics Department of Computer Science & Engineering The LNM Institute of Information Technology Raj Jaipur India Guangxi Key Laboratory of Cryptography and Information Security Guilin University of Electronic Technology Guangxi Guilin541004 China School of Mathematics Southwest Minzu University Chengdu610041 China School of Computer Science and Engineering University of Electronic Science and Technology of China Chengdu China

Data access control is one of the most essential key components of ensuring data security. The data access control is a selective restriction of data access, and it usually comprises two main security components: authentication and authorization. In this paper, we first propose an efficient data access control scheme for implantable medical devices. The protocol ensures anonymous data access control through a signcryption scheme with proxy reencryption (DAC-PRE) and supports the anonymity behavior of the user. Then the security of the scheme is proven in the random oracle model. Finally, We analyze the proposed protocol, and the results show that our scheme has very a low cost with respect to the computation time, communication overhead, as well as energy consumption. © 2022, The Authors. All rights reserved.

关键词： Energy utilization

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Association of PM_(2.5)Reduction with Improved Kidney Function:A Nationwide Quasiexperiment among Chinese Adults

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Health Data Science 2022年第1期2022卷 115-123页

作者： Yiqun Han Tao Xue Frank J.Kelly Yixuan Zheng Yao Yao Jiajianghui Li Jiwei Li Chun Fan Pengfei Li Tong Zhu Environmental Research Group MRC Centre for Environment and HealthImperial College LondonLondonUK BIC-ESAT and SKL-ESPC College of Environmental Sciences and EngineeringCenter for Environment and HealthPeking UniversityBeijing 100871China Institute of Reproductive and Child Health/Ministry of Health Key Laboratory of Reproductive Health and Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Center of Air Quality Simulation and System Analysis Chinese Academy of Environmental Planning100012 BeijingChina China Center for Health Development Studies Peking UniversityBeijingChina College of Computer Science and Technology Zhejiang UniversityHangzhouChina Computer Center Peking University and Peng Cheng LaboratoryChina Advanced Institute of Information Technology Peking UniversityChina

*** evidence from human studies has revealed the adverse impact of ambient fine particles(PM_(2.5))on health outcomes related to metabolic disorders and distant *** exposure to ambient PM_(2.5)leads to kidney impairment remains *** rapid air quality improvement driven by the clean air actions in China since 2013 provides an opportunity for a quasiexperiment to investigate the beneficial effect of PM_(2.5)reduction on kidney *** on two repeated nationwide surveys of the same population of 5115 adults in 2011 and 2015,we conducted a difference-indifference *** in long-term exposure to ambient PM_(2.5)were associated with changes in kidney function biomarkers,including estimated glomerular filtration rate by serum creatinine(GFRscr)or cystatin C(GFRcys),blood urea nitrogen(BUN),and uric acid(UA).*** a 10μg/m^(3)reduction in PM_(2.5),a significant improvement was observed for multiple kidney functional biomarkers,including GFRscr,BUN and UA,with a change of 0.42(95%confidence interval[CI]:0.06,0.78)mL/min/1.73m^(2),-0.38(-0.64,-0.12)mg/dL,and-0.06(-0.12,-0.00)mg/dL,respectively.A lower socioeconomic status,indicated by rural residence or low educational level,enhanced the adverse effect of PM_(2.5)on kidney *** results support a significant nephrotoxicity of PM_(2.5)based on multiple serum biomarkers and indicate a beneficial effect of improved air quality on kidney function.

关键词： Kidney organs ambient

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Semidiscrete optical vortex droplets in quasi-phase-matched photonic crystals

arXiv

引用

arXiv 2023年

作者： Xu, Xiaoxi Zhao, Feiyan Huang, Jiayao He, Hexiang Zhang, Li Chen, Zhaopin Nie, Zhongquan Malomed, Boris A. Li, Yongyao School of Physics and Optoelectronic Engineering Foshan University Foshan528000 China School of Electronic and Computer Engineering Peking University Shenzhen518055 China Physics Department Solid-State Institute Technion Haifa32000 Israel Key Lab of Advanced Transducers and Intelligent Control System Ministry of Education and Shanxi Province College of Electronic Information and Optical Engineering Taiyuan University of Technology Taiyuan030024 China Department of Physical Electronics School of Electrical Engineering Faculty of Engineering Tel Aviv University Tel Aviv69978 Israel Instituto de Alta Investigación Universidad de Tarapacá Casilla 7D Arica Chile Guangdong-Hong Kong-Macao Joint Laboratory for Intelligent Micro-Nano Optoelectronic Technology Foshan University Foshan528000 China

A new scheme for producing semidiscrete self-trapped vortices ("swirling photon droplets") in photonic crystals with competing quadratic (χ(2)) and self-defocusing cubic (χ(3)) nonlinearities is proposed. The photonic crystal is designed with a striped structure, in the form of spatially periodic modulation of the χ(2) susceptibility, which is imposed by the quasi-phase-matching technique. Unlike previous realizations of semidiscrete optical modes in composite media, built as combinations of continuous and arrayed discrete waveguides, the semidiscrete vortex "droplets" are produced here in the fully continuous medium. This work reveals that the system supports two types of semidiscrete vortex droplets, viz., onsite- and intersite-centered ones, which feature, respectively, odd and even numbers of stripes, N. Stability areas for the states with different values of N are identified in the system's parameter space. Some stability areas overlap with each other, giving rise to the multistability of states with different N. The coexisting states are mutually degenerate, featuring equal values of the Hamiltonian and propagation constant. An experimental scheme to realize the droplets is outlined, suggesting new possibilities for the long-distance transmission of nontrivial vortex beams in nonlinear media. © 2023, CC BY.

关键词： Photonic crystals

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Distributed Online Convex Optimization with Adversarial Constraints: Reduced Cumulative Constraint Violation Bounds under Slater’s Condition

arXiv

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arXiv 2023年

作者： Yi, Xinlei Li, Xiuxian Yang, Tao Xie, Lihua Hong, Yiguang Chai, Tianyou Johansson, Karl H. Lab for Information & Decision Systems Massachusetts Institute of Technology CambridgeMA02139 United States Department of Control Science and Engineering College of Electronics and Information Engineering Tongji University Shanghai201804 China Shanghai Research Institute for Intelligent Autonomous Systems China The State Key Laboratory of Synthetical Automation for Process Industries Northeastern University Shenyang110819 China School of Electrical and Electronic Engineering Nanyang Technological University 50 Nanyang Avenue Singapore639798 Singapore Division of Decision and Control Systems School of Electrical Engineering and Computer Science KTH Royal Institute of Technology Sweden Digital Futures Stockholm10044 Sweden

This paper considers distributed online convex optimization with adversarial constraints. In this setting, a network of agents makes decisions at each round, and then only a portion of the loss function and a coordinate block of the constraint function are privately revealed to each agent. The loss and constraint functions are convex and can vary arbitrarily across rounds. The agents collaborate to minimize network regret and cumulative constraint violation. A novel distributed online algorithm is proposed and it achieves an O(T max{c,1−c}) network regret bound and an O(T 1−c/2) network cumulative constraint violation bound, where T is the number of rounds and c ∈ (0, 1) is a user-defined trade-off parameter. When Slater’s condition holds (i.e, there is a point that strictly satisfies the inequality constraints), the network cumulative constraint violation bound is reduced to O(T 1−c). Moreover, if the loss functions are strongly convex, then the network regret bound is reduced to O(log(T)), and the network cumulative constraint violation bound is reduced to O(√log(T)T) and O(log(T)) without and with Slater’s condition, respectively. To the best of our knowledge, this paper is the first to achieve reduced (network) cumulative constraint violation bounds for (distributed) online convex optimization with adversarial constraints under Slater’s condition. Finally, the theoretical results are verified through numerical simulations. Copyright © 2023, The Authors. All rights reserved.

关键词： Economic and social effects

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Energy Efficiency and Delay Tradeoff in an MEC-Enabled Mobile IoT Network

arXiv

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arXiv 2022年

作者： Hu, Han Song, Weiwei Wang, Qun Hu, Rose Qingyang Zhu, Hongbo Jiangsu Key Laboratory of Wireless Communications Nanjing University of Posts and Telecommunications Nanjing210003 China Engineering Research Center of Health Service System Based on Ubiquitous Wireless Networks Ministry of Education Nanjing University of Posts and Telecommunications Nanjing210003 China Department of Electrical and Computer Engineering Utah State University LoganUT United States

Mobile Edge Computing (MEC) has recently emerged as a promising technology in the 5G era. It is deemed an effective paradigm to support computation intensive and delay critical applications even at energy-constrained and computation-limited Internet of Things (IoT) devices. To effectively exploit the performance benefits enabled by MEC, it is imperative to jointly allocate radio and computational resources by considering non-stationary computation demands, user mobility, and wireless fading channels. This paper aims to study the tradeoff between energy efficiency (EE) and service delay for multi-user multi-server MEC-enabled IoT systems when provisioning offloading services in a user mobility scenario. Particularly, we formulate a stochastic optimization problem with the objective of minimizing the long-term average network EE with the constraints of the task queue stability, peak transmit power, maximum CPU-cycle frequency, and maximum user number. To tackle the problem, we propose an online offloading and resource allocation algorithm by transforming the original problem into several individual subproblems in each time slot based on Lyapunov optimization theory, which are then solved by convex decomposition and submodular methods. Theoretical analysis proves that the proposed algorithm can achieve a [O(1/V), O(V)] tradeoff between EE and service delay. Simulation results verify the theoretical analysis and demonstrate our proposed algorithm can offer much better EE-delay performance in task offloading challenges, compared to several baselines. Copyright © 2022, The Authors. All rights reserved.

关键词： Internet of things

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