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REFUGE2 CHALLENGE: A TREASURE TROVE FOR MULTI-DIMENSION ANALYSIS AND EVALUATION IN GLAUCOMA SCREENING

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arXiv 2022年

作者： Fang, Huihui Li, Fei Wu, Junde Fu, Huazhu Sun, Xu Son, Jaemin Yu, Shuang Zhang, Menglu Yuan, Chenglang Bian, Cheng Lei, Baiying Zhao, Benjian Xu, Xinxing Li, Shaohua Fumero, Francisco Sigut, José Almubarak, Haidar Bazi, Yakoub Guo, Yuanhao Zhou, Yating Baid, Ujjwal Innani, Shubham Guo, Tianjiao Yang, Jie Orlando, José Ignacio Bogunović, Hrvoje Zhang, Xiulan Xu, Yanwu The REFUGE2 Challenge Australia State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center Sun Yat-Sen University Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science Guangzhou China Intelligent Healthcare Unit Baidu Inc. Beijing China The Institute of High Performance Computing Agency for Science Technology and Research Singapore Yatiris Group PLADEMA Institute CONICET UNICEN Tandil Argentina Christian Doppler Lab for Artificial Intelligence in Retina Department of Ophthalmology and Optometry Medical University of Vienna Vienna Austria VUNO Inc Seoul Korea Republic of Tencent HealthCare Tencent Shenzhen China Computer Vision Institute College of Computer Science and Software Engineering of Shenzhen University Shenzhen China School of Biomedical Engineering Health Science Center Shenzhen University China Xiaohe Healthcare ByteDance Guangdong Guangzhou510000 China School of Biomedical Engineering Shenzhen University China College of Computer Science & Software Engineering Shenzhen University China Department of Computer Science and Systems Engineering Universidad de La Laguna Spain Saudi Electronic University Saudi Arabia King Saud University Saudi Arabia Institute of Automation Chinese Academy of Sciences Beijing China University of Chinese Academy of Sciences Beijing China SGGS Institute of Engineering and Technology India Institute of Medical Robotics Shanghai Jiao Tong University China Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong University China

With the rapid development of artificial intelligence (AI) in medical image processing, deep learning in color fundus photography (CFP) analysis is also evolving. Although there are some open-source, labeled datasets of CFPs in the ophthalmology community, large-scale datasets for screening only have labels of disease categories, and datasets with annotations of fundus structures are usually small in size. In addition, labeling standards are not uniform across datasets, and there is no clear information on the acquisition device. Here we release a multi-annotation, multi-quality, and multi-device color fundus image dataset for glaucoma analysis on an original challenge-Retinal Fundus Glaucoma Challenge 2nd Edition (REFUGE2). The REFUGE2 dataset contains 2000 color fundus images with annotations of glaucoma classification, optic disc/cup segmentation, as well as fovea localization. Meanwhile, the REFUGE2 challenge sets three sub-tasks of automatic glaucoma diagnosis and fundus structure analysis and provides an online evaluation framework. Based on the characteristics of multi-device and multi-quality data, some methods with strong generalizations are provided in the challenge to make the predictions more robust. This shows that REFUGE2 brings attention to the characteristics of real-world multi-domain data, bridging the gap between scientific research and clinical application. © 2022, CC BY-NC-ND.

关键词： Color

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反向连边在大型分层网络中的影响（英文）

Engineering 2024年第5期 240-249页

作者：曹浩森胡斌斌莫小雨陈都鑫高建喜袁烨陈关荣 Tamás Vicsek 管晓宏张海涛 MOE Engineering Research Center of Autonomous Intelligent Unmanned Systems State Key Laboratory of Intelligent Manufacturing Equipment and Technology School of Artificial Intelligence and Automation Huazhong University of Science and Technology School of Mechanical and Aerospace Engineering Nanyang Technological University Jiangsu Key Laboratory of Networked Collective Intelligence School of Mathematics Southeast University Department of Computer Science Rensselaer Polytechnic Institute Department of Electronic Engineering City University of Hong Kong Department of Biological Physics E?tv?s University MOE Key Laboratory for Intelligent Networks and Network Security School of Automation Science and Engineering Xi'an Jiaotong University

Hierarchical networks are frequently encountered in animal groups, gene networks, and artificial engineering systems such as multiple robots, unmanned vehicle systems, smart grids, wind farm networks,and so forth. The structure of a large directed hierarchical network is often strongly influenced by reverse edges from lower-to higher-level nodes, such as lagging birds' howl in a flock or the opinions of lowerlevel individuals feeding back to higher-level ones in a social group. This study reveals that, for most large-scale real hierarchical networks, the majority of the reverse edges do not affect the synchronization process of the entire network; the synchronization process is influenced only by a small part of these reverse edges along specific paths. More surprisingly, a single effective reverse edge can slow down the synchronization of a huge hierarchical network by over 60%. The effect of such edges depends not on the network size but only on the average in-degree of the involved subnetwork. The overwhelming majority of active reverse edges turn out to have some kind of ‘‘bunchingo effect on the information flows of hierarchical networks, which slows down synchronization processes. This finding refines the current understanding of the role of reverse edges in many natural, social, and engineering hierarchical networks,which might be beneficial for precisely tuning the synchronization rhythms of these networks. Our study also proposes an effective way to attack a hierarchical network by adding a malicious reverse edge to it and provides some guidance for protecting a network by screening out the specific small proportion of vulnerable nodes.

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Multi-objective predictive taxi dispatch via network flow optimization∗

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arXiv 2020年

作者： Kim, Beomjun Kim, Jeongho Huh, Subin You, Seungil Yang, Insoon Department of Electrical and Computer Engineering Seoul National University Seoul08826 Korea Republic of Institute of New Media and Communications Seoul National University Seoul08826 Korea Republic of Automation and Systems Research Institute Seoul National University Seoul08826 Korea Republic of Kakao Mobility Gyeonggi-do13494 Korea Republic of

In this paper, we discuss a large-scale fleet management problem in a multi-objective setting. We aim to seek a receding horizon taxi dispatch solution that serves as many ride requests as possible while minimizing the cost of relocating vehicles. To obtain the desired solution, we first convert the multi-objective taxi dispatch problem into a network flow problem, which can be solved using the classical minimum cost maximum flow (MCMF) algorithm. We show that a solution obtained using the MCMF algorithm is integer-valued;thus, it does not require any additional rounding procedure that may introduce undesirable numerical errors. Furthermore, we prove the time-greedy property of the proposed solution, which justifies the use of receding horizon optimization. For computational efficiency, we propose a linear programming method to obtain an optimal solution in near real time. The results of our simulation studies using the real-world data for the metropolitan area of Seoul, South Korea indicate that the performance of the proposed predictive method is almost as good as that of the oracle that foresees the future. Copyright © 2020, The Authors. All rights reserved.

关键词： Linear programming

Reliable distributed Computing for Metaverse: A Hierarchical Game-Theoretic Approach

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arXiv 2021年

作者： Jiang, Yuna Kang, Jiawen Niyato, Dusit Ge, Xiaohu Xiong, Zehui Miao, Chunyan Shen, Xuemin School of Electronic Information and Communications Huazhong University of Science and Technology Hubei Wuhan430074 China Shenzhen Huazhong University Science and Technology Research Institute Guangdong Shenzhen518063 China The School of Automation Guangdong University of Technology Guangdong Guangzhou510006 China The School of Computer Science and Engineering Nanyang Technological University Singapore639798 Singapore The Pillar of Information Systems Technology and Design Singapore University of Technology and Design Singapore487372 Singapore The Department of Electrical and Computer Engineering University of Waterloo WaterlooONN2L 3G1 Canada

The metaverse is regarded as a new wave of technological transformation that provides a virtual space for people to interact through digital avatars. To achieve immersive user experiences in the metaverse, real-time rendering is the key technology. However, computing intensive tasks of real-time rendering from metaverse service providers cannot be processed efficiently on a single resource-limited mobile device. Alternatively, such mobile devices can offload the metaverse rendering tasks to other mobile devices by adopting the collaborative computing paradigm based on Coded distributed Computing (CDC). Therefore, this paper introduces a hierarchical game-theoretic CDC framework for the metaverse services, especially for vehicular metaverse. In the framework, idle resources from vehicles, acting as CDC workers, are aggregated to handle intensive computation tasks in the vehicular metaverse. Specifically, in the upper layer, a miner coalition formation game is formulated based on a reputation metric to select reliable workers. To guarantee the reliable management of reputation values, the reputation values calculated based on the subjective logical model are maintained in a blockchain database. In the lower layer, a Stackelberg game based incentive mechanism is considered to attract reliable workers selected in the upper layer to participate in rendering tasks. The simulation results illustrate that the proposed framework is resistant to malicious workers. Compared with the best-effort worker selection scheme, the proposed scheme can improve the utility of metaverse service provider and average profit of CDC workers. Copyright © 2021, The Authors. All rights reserved.

关键词： Blockchain

Delays in Model Reduction of Chemical Reaction Networks

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IFAC-PapersOnLine 2018年第14期51卷 100-105页

作者： Lipták, György Hangos, Katalin M. Process Control Research Group Systems and Control Laboratory Computer and Automation Research Institute Hungarian Academy of Sciences P.O. Box 63 BudapestH-1518 Hungary Department of Electrical Engineering and Information Systems University of Pannonia Veszprém Hungary

A novel engineering model reduction method is proposed in this paper that can be applied to a chemical reaction network (CRN) with chains of linear reactions. The reduced model is a delayed CRN with possibly different delays but with less state variables than the original model. As the first step of the model reduction, a decomposition method is also developed to transform chains with joint reactions into independent chains of linear reactions. The well known example of McKeithan's network is used as a case study to illustrate the basic concepts and the design method. © 2018

关键词： Reduction

HomeCA: Scalable Secure IoT Network Integration 49

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HomeCA: Scalable Secure IoT Network Integration

49. Jahrestagung der Gesellschaft fur Informatik: 50 Jahre Gesellschaft fur Informatik - Informatik fur Gesellschaft, INFORMATIK 2019 - 49th Annual Meeting of the German Informatics Society: 50 years of the German Informatics Society - computer Science for Society, INFORMATICS 2019

作者： Müller, Robert Schmitt, Corinna Kaiser, Daniel Waldvogel, Marcel Department of Computer and Information Science Distributed Systems Laboratory Universität Konstanz Konstanz78457 Germany Research Institute Code Universität der Bundeswehr München Werner-Heisenberg-Weg 39 Neubiberg85577 Germany Security and Networking Research Group Netlab Maison du Nombre 6 University of Luxembourg Avenue de la Fonte Esch-sur-Alzette4364 Luxembourg

ISBN: (纸本)9783885796886

Integrating Internet of Things (IoT) devices into an existing network is a nightmare. Minimalistic, unfriendly user interfaces, if any;badly chosen security methods, most notably the defaults;lack of long term security;and bugs or misconAgurations are plentiful. As a result, an increasing number of owners operate unsecure devices. Our investigations into the root causes of the problems resulted in the development of Home CertiAcate Authority (HomeCA). HomeCAincludes a comprehensive set of secure, vendor-independent interoperable practices based on existing protocols and open standards. HomeCA avoids most of the current pitfalls in network integration by design. Long-term protocol security, permission management, and secure usage combined with simpliAed device integration and secure key updates on ownership acquisition pave the way toward scalable, federated IoT security. © 2019 Gesellschaft fur Informatik (GI). All rights reserved.

关键词： Network security

distributed delay model of the McKeithan’s network

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IFAC-PapersOnLine 2019年第7期52卷 33-38页

作者： György Lipták Katalin M. Hangos Process Control Research Group Systems and Control Laboratory Computer and Automation Research Institute Hungarian Academy of Sciences P.O. Box 63 H-1518 Budapest Hungary Department of Electrical Engineering and Information Systems University of Pannonia Veszprém Hungary

In this paper CRNs containing linear reaction chains with multiple joint complexes were considered in order to obtain an equivalent reduced order delayed CRN model with distributed time delays. For this purpose, our earlier method (Lipták and Hangos (2018)) for decomposing the chains of linear reactions with multiple joint complexes was used together with the "linear chain trick". An analytical expression for the kernel function of the distributed delay was also derived from the reaction rate coefficients of the linear reaction chains. Our approach was demonstrated using the example of the well known McKeithan’s network model of kinetic proofreading.

关键词： Process control Delay Chemical Reaction Networks

Understanding metric-related pitfalls in image analysis validation

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arXiv 2023年

作者： Reinke, Annika Tizabi, Minu D. Baumgartner, Michael Eisenmann, Matthias Heckmann-Nötzel, Doreen Kavur, A. Emre Rädsch, Tim Sudre, Carole H. Acion, Laura Antonelli, Michela Arbel, Tal Bakas, Spyridon Benis, Arriel Blaschko, Matthew B. Buettner, Florian Cardoso, M. Jorge Cheplygina, Veronika Chen, Jianxu Christodoulou, Evangelia Cimini, Beth A. Collins, Gary S. Farahani, Keyvan Ferrer, Luciana Galdran, Adrian van Ginneken, Bram Glocker, Ben Godau, Patrick Haase, Robert Hashimoto, Daniel A. Hoffman, Michael M. Huisman, Merel Isensee, Fabian Jannin, Pierre Kahn, Charles E. Kainmueller, Dagmar Kainz, Bernhard Karargyris, Alexandros Karthikesalingam, Alan Kenngott, Hannes Kleesiek, Jens Kofler, Florian Kooi, Thijs Kopp-Schneider, Annette Kozubek, Michal Kreshuk, Anna Kurc, Tahsin Landman, Bennett A. Litjens, Geert Madani, Amin Maier-Hein, Klaus Martel, Anne L. Mattson, Peter Meijering, Erik Menze, Bjoern Moons, Karel G.M. Müller, Henning Nichyporuk, Brennan Nickel, Felix Petersen, Jens Rafelski, Susanne M. Rajpoot, Nasir Reyes, Mauricio Riegler, Michael A. Rieke, Nicola Saez-Rodriguez, Julio Sánchez, Clara I. Shetty, Shravya Summers, Ronald M. Taha, Abdel A. Tiulpin, Aleksei Tsaftaris, Sotirios A. van Calster, Ben Varoquaux, Gaël Yaniv, Ziv R. Jäger, Paul F. Maier-Hein, Lena Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Heidelberg Division of Intelligent Medical Systems Germany NCT Heidelberg A Partnership Between DKFZ University Medical Center Heidelberg Germany Heidelberg Division of Medical Image Computing Germany Heidelberg Division of Intelligent Medical Systems Germany MRC Unit for Lifelong Health and Ageing UCL Centre for Medical Image Computing Department of Computer Science University College London London United Kingdom School of Biomedical Engineering and Imaging Science King’s College London London United Kingdom Instituto de Cálculo CONICET – Universidad de Buenos Aires Buenos Aires Argentina Centre for Medical Image Computing University College London London United Kingdom McGill University Montreal Canada Division of Computational Pathology Dept of Pathology & Laboratory Medicine Indiana University School of Medicine IU Health Information and Translational Sciences Building Indianapolis United States University of Pennsylvania Richards Medical Research Laboratories FL7 PhiladelphiaPA United States Department of Digital Medical Technologies Holon Institute of Technology Holon Israel European Federation for Medical Informatics Le Mont-sur-Lausanne Switzerland Center for Processing Speech and Images Department of Electrical Engineering KU Leuven Leuven Belgium partner site Frankfurt/Mainz a partnership between DKFZ and UCT Frankfurt Marburg Germany Heidelberg Germany Goethe University Frankfurt Department of Medicine Germany Goethe University Frankfurt Department of Informatics Germany and Frankfurt Cancer Insititute Germany Department of Computer Science IT University of Copenhagen Copenhagen Denmark Leibniz-Institut für Analytische Wissenschaften – ISAS – e.V. Dortmund Germany Imaging Platform Broad Institute of MIT and Harvard CambridgeMA United States Centre for Statistics in Medicine University of Oxford Oxford United Kingdom Center for Biomedical In

Validation metrics are key for tracking scientific progress and bridging the current chasm between artificial intelligence (AI) research and its translation into practice. However, increasing evidence shows that particularly in image analysis, metrics are often chosen inadequately. While taking into account the individual strengths, weaknesses, and limitations of validation metrics is a critical prerequisite to making educated choices, the relevant knowledge is currently scattered and poorly accessible to individual researchers. Based on a multi-stage Delphi process conducted by a multidisciplinary expert consortium as well as extensive community feedback, the present work provides the first reliable and comprehensive common point of access to information on pitfalls related to validation metrics in image analysis. While focused on biomedical image analysis, the addressed pitfalls generalize across application domains and are categorized according to a newly created, domain-agnostic taxonomy. The work serves to enhance global comprehension of a key topic in image analysis validation. © 2023, CC BY.

关键词： computer vision

Hamilton–Jacobi–Bellman Equations for Q-Learning in Continuous Time∗

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arXiv 2019年

作者： Kim, Jeongho Yang, Insoon Institute of New Media and Communications Seoul National University Seoul08826 Korea Republic of Department of Electrical and Computer Engineering Automation and Systems Research Institute Seoul National University Seoul08826 Korea Republic of

In this paper, we introduce Hamilton–Jacobi–Bellman (HJB) equations for Q-functions in continuous time optimal control problems with Lipschitz continuous controls. The standard Q-function used in reinforcement learning is shown to be the unique viscosity solution of the HJB equation. A necessary and sufficient condition for optimality is provided using the viscosity solution framework. By using the HJB equation, we develop a Q-learning method for continuous-time dynamical systems. A DQN-like algorithm is also proposed for high-dimensional state and control spaces. The performance of the proposed Q-learning algorithm is demonstrated using 1-, 10- and 20-dimensional dynamical systems. Copyright © 2019, The Authors. All rights reserved.

关键词： Reinforcement learning