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Erratum: “Enhanced acoustic pressure sensors based on coherent perfect absorber-laser effect” [J. Appl. Phys. 129, 104902 (2021)]

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Journal of Applied Physics 2021年第22期129卷

作者： Mohamed Farhat Waqas W. Ahmad Abdelkrim Khelif Khaled N. Salama Ying Wu 1Computer Electrical and Mathematical Science and Engineering (CEMSE) Division King Abdullah University of Science and Technology (KAUST) Thuwal 23955-6900 Saudi Arabia 2Institut FEMTO-ST CNRS Universite de Bourgogne Franche-Comte 25000 Besancon France 3Sensors Lab Advanced Membranes & Porous Materials Center (AMPMC) King Abdullah University of Science and Technology (KAUST) Thuwal 23955 Saudi Arabia

There is a typo in Eq. (2) of the original paper.1 The corrected form of this equation is

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A Unified Moment-Based Approach for the Evaluation of the Outage Probability with Noise and Interference

A Unified Moment-Based Approach for the Evaluation of the Ou...

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作者： Ben Rached, Nadhir Kammoun, Abla Alouini, Mohamed-Slim Tempone, Raul Computer Electrical and Mathematical Science and Engineering Division King Abdullah University of Science and Technology Thuwal Saudi Arabia

In this paper, we develop a novel moment-based approach for the evaluation of the outage probability (OP) in a generalized fading environment with interference and noise. Our method is based on the derivation of a power series expansion of OP of the signal-to-interference-plus-noise ratio. It does not necessitate stringent requirements, the only major ones being the existence of a power series expansion of the cumulative distribution function of the desired user power and the knowledge of the cross moments of the interferers' powers. The newly derived formula is shown to be applicable for most of the well-practical fading models of the desired user under some assumptions on the parameters of the powers' distributions. A further advantage of our method is that it is applicable irrespective of the nature of the fading models of the interfering powers, the only requirement being the perfect knowledge of their cross moments. In order to illustrate the wide scope of applicability of our technique, we present a convergence study of the provided formula for the Generalized Gamma and the Rice fading models. Moreover, we show that our analysis has direct bearing on recent multi-channel applications using selection diversity techniques. Finally, we assess by simulations the accuracy of the proposed formula for various fading environments. © 2016 IEEE.

关键词： Distribution functions

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Magnetization reversal and local switching fields of ferromagnetic Co/Pd microtubes with radial magnetization

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Physical Review B 2019年第9期99卷 094438-094438页

作者： Norbert Puwenberg Christopher F. Reiche Robert Streubel Mishal Khan Dipankar Mukherjee Ivan V. Soldatov Michael Melzer Oliver G. Schmidt Bernd Büchner Thomas Mühl Leibniz Institute for Solid State and Materials Research IFW Dresden 01069 Dresden Germany Institute of Solid State and Materials Physics Technische Universität Dresden 01069 Dresden Germany Department of Electrical and Computer Engineering University of Utah Salt Lake City Utah 84112 USA Materials Sciences Division Lawrence Berkeley National Laboratory Berkeley California 94720 USA Material Systems for Nanoelectronics Technische Universität Chemnitz 09107 Chemnitz Germany

Three-dimensional nanomagnetism is a rapidly growing field of research covering both noncollinear spin textures and curved magnetic geometries including microtubular structures. We spatially resolve the field-induced magnetization reversal of free-standing ferromagnetic microtubes utilizing multifrequency magnetic force microscopy (MFM). The microtubes are composed of Co/Pd multilayer films with perpendicular magnetic anisotropy that translates to an anisotropy with radial easy axis upon rolling-up. Simultaneously mapping the topography and the perpendicular magnetostatic force derivative, the relation between surface angle and local magnetization configuration is evaluated for a large number of locations with slopes exceeding 45 degrees. The angle-dependence of the switching field is concurrent with the Kondorsky model, i.e., the rolled-up nanomembrane behaves like a planar magnetic film with perpendicular anisotropy and a pinning dominated magnetization reversal. Additionally, we discuss methodological challenges when detecting magnetostatic force derivatives near steep surfaces.

关键词： Ferromagnetism Spin texture

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Single-cell stochastic gene expression kinetics with coupled positive-plus-negative feedback

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Physical Review E 2019年第5期100卷 052406-052406页

作者： Chen Jia Le Yi Wang George G. Yin Michael Q. Zhang Division of Applied and Computational Mathematics Beijing Computational Science Research Center Beijing 100193 China Department of Mathematics Wayne State University Detroit Michigan 48202 USA Department of Electrical and Computer Engineering Wayne State University Detroit Michigan 48202 USA Department of Biological Sciences Center for Systems Biology University of Texas at Dallas Richardson Texas 75080 USA MOE Key Laboratory of Bioinformatics Center for Synthetic and Systems Biology Tsinghua University Beijing 100084 China

Here we investigate single-cell stochastic gene expression kinetics in a minimal coupled gene circuit with positive-plus-negative feedback. A triphasic stochastic bifurcation is observed upon increasing the ratio of the positive and negative feedback strengths, which reveals a strong synergistic interaction between positive and negative feedback loops. We discover that coupled positive-plus-negative feedback amplifies gene expression mean but reduces gene expression noise over a wide range of feedback strengths when promoter switching is relatively slow, stabilizing gene expression around a relatively high level. In addition, we study two types of macroscopic limits of the discrete chemical master equation model: the Kurtz limit applies to proteins with large burst frequencies and the Lévy limit applies to proteins with large burst sizes. We derive the analytic steady-state distributions of the protein abundance in a coupled gene circuit for both the discrete model and its two macroscopic limits, generalizing the results obtained by Liu et al. [Chaos 26, 043108 (2016)]. We also obtain the analytic time-dependent protein distribution for the classical Friedman-Cai-Xie random bursting model [Friedman, Cai, and Xie, Phys. Rev. Lett. 97, 168302 (2006)]. Our analytic results are further applied to study the structure of gene expression noise in a coupled gene circuit, and a complete decomposition of noise in terms of five different biophysical origins is provided.

关键词： Gene expression Stochastic processes Gene regulatory networks Markovian processes

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Reports of the AAAI 2017 fall symposium series

Reports of the AAAI 2017 fall symposium series

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作者： Flenner, Arjuna Fraune, Marlena R. Hiatt, Laura M. Kendall, Tony Laird, John E. Lebiere, Christian Rosenbloom, Paul S. Stein, Frank Topp, Elin A. Unhelkar, Vaibhav V. Zhao, Ying NAVAIR China Lake United States Indiana University United States WashingtonDC United States Naval Postgraduate School United States Computer Science and Engineering Division Electrical Engineering and Computer Science Department University of Michigan United States Psychology Department Carnegie Mellon University United States Department of Computer Science Institute for Creative Technologies University of Southern California United States Analytics Solution Center IBM United States Lund University Lund Sweden Massachusetts Institute of Technology United States Naval Postgraduate School United States

The AAAI 2017 Fall Symposium Series was held Thursday through Saturday, November 9–11, at the Westin Arlington Gateway in Arlington, Virginia, adjacent to Washington, DC. The titles of the six symposia were Artificial Intelligence for Human-Robot Interaction;Cognitive Assistance in Government and Public Sector Applications;Deep Models and Artificial Intelligence for Military Applications: Potentials, Theories, Practices, Tools, and Risks;Human-Agent Groups: Studies, Algorithms, and Challenges;Natural Communication for Human-Robot Collaboration;and A Standard Model of the Mind. The highlights of each symposium (except the Natural Communication for Human-Robot Collaboration symposium, whose organizers did not submit a report) are presented in this report. Copyright © 2018, Association for the Advancement of Artificial Intelligence. All rights reserved.

关键词： Military applications

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A Target Recycling Amplification Process for the Digital Detection of Exosomal MicroRNAs through Photonic Resonator Absorption Microscopy

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Angewandte Chemie 2023年第16期135卷

作者： Dr. Xiaojing Wang Skye Shepherd Dr. Nantao Li Dr. Congnyu Che Dr. Tingjie Song Yanyu Xiong Isabella Rose Palm Dr. Bin Zhao Dr. Manish Kohli Prof. Utkan Demirci Prof. Yi Lu Prof. Brian T. Cunningham Nick Holonyak Jr. Micro and Nanotechnology Laboratory University of Illinois at Urbana-Champaign Urbana IL 61801 USA Carl R. Woese Institute for Genomic Biology University of Illinois at Urbana-Champaign Urbana IL 61801 USA Department of Bioengineering University of Illinois at Urbana-Champaign Urbana IL 61801 USA Department of Electrical and Computer Engineering University of Illinois at Urbana-Champaign Urbana IL 61801 USA Department of Chemistry University of Illinois at Urbana-Champaign Urbana IL 61801 USA Division of Oncology University of Utah School of Medicine Huntsman Cancer Institute Salt Lake City 84112 USA Canary Center at Stanford for Cancer Early Detection Bio Acoustic-MEMS in Medicine (BAMM) Laboratory Department of Radiology School of Medicine Stanford University Palo Alto CA 94304 USA

Exosomal microRNAs (miRNAs) have considerable potential as pivotal biomarkers to monitor cancer development, dis-ease progression, treatment effects and prognosis. Here, we report an efficient target recycling amplification process (TRAP) for the digital detection of miRNAs using photonic resonator absorption microscopy. We achieve multiplex digital detection with sub-attomolar sensitivity in 20 minutes, robust selectivity for single nucleotide variants, and a broad dynamic range from 1 aM to 1 pM. Compared with traditional qRT-PCR, TRAP showed similar accuracy in profiling exosomal miRNAs derived from cancer cells, but also exhibited at least 31-fold and 61-fold enhancement in the limits of miRNA-375 and miRNA-21 detection, respectively. The TRAP approach is ideal for exosomal or circulating miRNA biomarker quantification, where the miRNAs are present in low concentrations or sample volume, with potentials for frequent, low-cost, and minimally invasive point-of-care testing.

关键词： Amplification Cancer Diagnostics DNA Toehold Probe Exosomal miRNA Photonic Sensor

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DESHIMA 2.0: Rapid redshift surveys and multi-line spectroscopy of dusty galaxies

arXiv

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arXiv 2021年

作者： Rybak, Matus Bakx, T. Baselmans, J. Karatsu, K. Kohno, K. Takekoshi, T. Tamura, Y. Taniguchi, A. van der Werf, P. Endo, A. Faculty of Electrical Engineering Mathematics and Computer Science Delft University of Technology Mekelweg 4 Delft2628 CD Netherlands Leiden Observatory Leiden University Niels Bohrweg 2 Leiden2333 CA Netherlands Division of Particle and Astrophysical Science Graduate School of Science Nagoya University Furocho Chikusa-ku Aichi Nagoya464-8602 Japan National Astronomical Observatory of Japan 2-21-1 Osawa Tokyo Mitaka181-8588 Japan SRON Netherlands Institute for Space Research Niels Bohrweg 4 Leiden2333 CA Netherlands Institute of Astronomy Graduate School of Science The University of Tokyo 2-21-1 Osawa Tokyo Mitaka181-0015 Japan Research Center for the Early Universe Graduate School of Science The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo113-0033 Japan Kitami Institute of Technology 165 Koen-cho Hokkaido Kitami090-8507 Japan

We present a feasibility study for the high-redshift galaxy part of the Science Verification Campaign with the 220-440 GHz DESHIMA 2.0 integrated superconducting spectrometer on the ASTE telescope. The first version of the DESHIMA 2.0 chip has been recently manufactured and tested in the lab. Based on these realistic performance measurements, we evaluate potential target samples and prospects for detecting the [CII] and CO emission lines. The planned observations comprise two distinct, but complementary objectives: (1) acquiring spectroscopic redshifts for dusty galaxies selected in far-infrared/mm-wave continuum surveys;(2) multi-line observations to infer physical conditions in dusty galaxies. © 2021, CC BY.

关键词： Galaxies

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Author Correction: The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing

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Nature neuroscience 2023年第10期26卷 1833页

作者： Rachel E Rodin Yanmei Dou Minseok Kwon Maxwell A Sherman Alissa M D'Gama Ryan N Doan Lariza M Rento Kelly M Girskis Craig L Bohrson Sonia N Kim Ajay Nadig Lovelace J Luquette Doga C Gulhan Peter J Park Christopher A Walsh Division of Genetics and Genomics Manton Center for Orphan Disease Research and Howard Hughes Medical Institute Boston Children's Hospital Boston MA USA. Departments of Pediatrics and Neurology Harvard Medical School Boston MA USA. Department of Biomedical Informatics Harvard Medical School Boston MA USA. Department of Electrical Engineering and Computer Science MIT Cambridge MA USA. Division of Genetics Brigham and Women's Hospital Boston MA USA. Broad Institute of MIT and Harvard Cambridge MA USA. Department of Biomedical Informatics Harvard Medical School Boston MA USA. peter_park@hms.harvard.edu. Division of Genetics Brigham and Women's Hospital Boston MA USA. peter_park@hms.harvard.edu. Division of Genetics and Genomics Manton Center for Orphan Disease Research and Howard Hughes Medical Institute Boston Children's Hospital Boston MA USA. Christopher.walsh@childrens.harvard.edu. Departments of Pediatrics and Neurology Harvard Medical School Boston MA USA. Christopher.walsh@childrens.harvard.edu. Broad Institute of MIT and Harvard Cambridge MA USA. Christopher.walsh@childrens.harvard.edu.

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TiEMPO: Open-source time-dependent end-to-end model for simulating ground-based submillimeter astronomical observations

arXiv

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arXiv 2021年

作者： Huijten, Esmee Roelvink, Yannick Brackenhoff, Stefanie A. Taniguchi, Akio Bakx, Tom J.L.C. Marthi, Kaushal B. Zaalberg, Stan Baselmans, Jochem J.A. Chin, Kah Wuy Huiting, Robert Karatsu, Kenichi Laguna, Alejandro Pascual Tamura, Yoichi Takekoshi, Tatsuya Yates, Stephen J.C. van Hoven, Maarten Endo, Akira Faculty of Electrical Engineering Mathematics and Computer Science Delft University of Technology Mekelweg 4 Delft2628 CD Netherlands Kavli Institute of NanoScience Faculty of Applied Sciences Delft University of Technology Lorentzweg 1 Delft2628 CJ Netherlands Division of Particle and Astrophysical Science Graduate School of Science Nagoya University Aichi464-8602 Japan Kapteyn Astronomical Institute University of Groningen P.O. Box 800 Groningen9700 AV Netherlands SRON—Netherlands Institute for Space Research Sorbonnelaan 2 Utrecht3584 CA Netherlands National Astronomical Observatory of Japan Mitaka Tokyo181-8588 Japan Department of Astronomy School of Science University of Tokyo Bunkyo Tokyo113-0033 Japan Institute of Astronomy Graduate School of Science The University of Tokyo 2-21-1 Osawa Mitaka Tokyo181-0015 Japan SRON—Netherlands Institute for Space Research Landleven 12 Groningen9747 AD Netherlands

The next technological breakthrough in millimeter-submillimeter astronomy is 3D imaging spectrometry with wide instantaneous spectral bandwidths and wide fields of view. The total optimization of the focal-plane instrument, the telescope, the observing strategy, and the signal-processing software must enable efficient removal of foreground emission from the Earth’s atmosphere, which is time-dependent and highly nonlinear in frequency. Here we present TiEMPO: Time-dependent End-to-end Model for Post-process Optimization of the DESHIMA spectrometer. TiEMPO utilizes a dynamical model of the atmosphere and parametrized models of the astronomical source, the telescope, the instrument, and the detector. The output of TiEMPO is a timestream of sky brightness temperature and detected power, which can be analyzed by standard signal-processing software. We first compare TiEMPO simulations with an on-sky measurement by the wideband DESHIMA spectrometer, and find good agreement in the noise power spectral density and sensitivity. We then use TiEMPO to simulate the detection of the line emission spectrum of a high-redshift galaxy using the DESHIMA 2.0 spectrometer in development. The TiEMPO model is open source. Its modular and parametrized design enables users to adapt it to design and optimize the end-to-end performance of spectroscopic and photometric instruments on existing and future telescopes. Copyright © 2021, The Authors. All rights reserved.

关键词： Millimeter waves

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Optimal threshold-based control policies for persistent monitoring on graphs

arXiv

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arXiv 2018年

作者： Zhou, Nan Cassandras, Christos G. Yu, Xi Andersson, Sean B. Division of Systems Engineering Boston University BostonMA02215 United States Department of Electrical and Computer Engineering Boston University BostonMA02215 United States Department of Mechanical Engineering Boston University BostonMA02215 United States

We consider the optimal multi-agent persistent monitoring problem defined by a team of cooperating agents visiting a set of nodes (targets) on a graph with the objective of minimizing a measure of overall node state uncertainty. The solution to this problem involves agent trajectories defined both by the sequence of nodes to be visited by each agent and the amount of time spent at each node. Since such optimal trajectories are generally intractable, we propose a class of distributed threshold-based parametric controllers through which agent transitions from one node to the next are controlled by threshold parameters on the node uncertainty states. The resulting behavior of the agent-target system can be described by a hybrid dynamic system. This enables the use of Infinitesimal Perturbation Analysis (IPA) to determine on line (locally) optimal threshold parameters through gradient descent methods and thus obtain optimal controllers within this family of threshold-based policies. We further show that in a single-agent case the IPA gradient is monotonic, which implies a simple structure whereby an agent visiting a node should reduce the uncertainty state to zero before moving to the next node. Simulation examples are included to illustrate our results and compare them to optimal solutions derived through dynamic programming when this is possible. Copyright © 2018, The Authors. All rights reserved.

关键词： Gradient methods

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