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7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro

作者： Loeckx, D. Maes, F. Vandermeulen, D. Suetens, P. Medical Image Computing ESAT/PSI Katholieke Universiteit Leuven Belgium

ISBN: (纸本)9781424441266

Recently, different approaches have emerged for voxel based nonrigid image registration using local instead of global similarity measures. Benefits are more accurate registration or the ability to subdivide the global similarity in local contributions. Within this article, we provide a general method to localise similarity measures using overlapping regions. Moreover, we extend the concept of partial volume estimation, introduced for mutual information (MI), to other similarity measures. We compare local and global sum of squared differences (SSD), cross correlation (CC) and MI for different sizes of the local regions. In general, local MI gives the highest accuracy, even for image pairs of the same modality. Partial volume estimation slightly improves the accuracy for local measures;the improvement is more pronounced for label images.

关键词： voxel-based similarity measure nonrigid registration mutual information

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Subtraction CT angiography using non-rigid registration: The impact of similarity measure and image pre-processing

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International Congress Series 2005年 1281卷 328-333页

作者： Drisis, S. Srivastava, S. Seghers, D. Coudyzer, W. Maes, F. Suetens, P. Marchal, G. Radiology Department Gasthuisberg University Hospital Belgium Medical Image Computing PSI ESAT KU Leuven Belgium

Subtraction CT Angiography is susceptible to motion artifacts especially when abdomen is the area under examination. The purpose of this study was to compare two non-rigid registration algorithms, one, using maximization of mutual information and the other, using sum of squared differences as a similarity measure and to evaluate their registration performance. Furthermore the impact of pre-processing of the images (native images versus edge weighted images) on the registration quality for registration of the abdomen prior to subtraction was assessed. Maximization of the mutual information performed better than sum of squared differences and edge weighted images performed better than native images especially when plaques were considered. Edge weighted images preserve the volume of plaques and bones, thus increasing the registration performance for subtraction CT angiography. © 2005 CARS and Elsevier B.V.

关键词： Mutual information Non-rigid registration Subtraction CT angiography

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Computer aided diagnosis for virtual Colonography 4th

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4th International Conference on medical image computing and Computer-Assisted Intervention, MICCAI 2001

作者： Kiss, Gabriel Van Cleynenbreugel, Johan Thomeer, Maarten Suetens, Paul Marchal, Guy Medicine and Engineering Medical Image Computing Radiology - ESAT/PSI University Hospital Gasthuisberg Herestraat 49 LeuvenB-3000 Belgium

ISBN: (纸本)3540426973

The success of CT colonography (CTC) depends on appropriate tools for quick and accurate diagnostic reading. Current advancements in computer technology have the potential to bring such tools even to the PC level. In this paper a technique for Computed Aided Diagnosis (CAD) using CT colonography is described. The method labels positions in the volume data, which have a strong likelihood of being polyps and presents them in a user- friendly way. This method will reduce the amount of time needed by the radiologist to make a correct diagnosis. The method was tested on a study group of 18 patients and the sensitivity for polyps of 10 mm or larger was 100%, comparable to that of human readers. The price paid for a high detection rate was a large number of approximately 8 false positive findings per case. © Springer-Verlag Berlin Heidelberg 2001.

关键词： Computer aided diagnosis

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Retrospective correction of the heel effect in hand radiographs 4th

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4th International Conference on medical image computing and Computer-Assisted Intervention, MICCAI 2001

作者： Behiels, G. Maes, F. Vandermeulen, D. Suetens, P. Katholieke Universiteit Leuven Medical Image Computing [Radiology - ESAT/PSI University Hospital Gasthuisberg Herestraat 49 LeuvenB-3000 Belgium

ISBN: (纸本)3540426973

A method for retrospective correction of intensity inhomogeneities induced by the heel effect in digital radiographs is presented. The method is based on a mathematical model for the heel effect derived from the acquisition geometry. The model parameters are estimated by fitting the model to the image intensity data in the background or direct exposure area only where the heel effect is directly measurable, while the correction is then applied to the whole image. The method iterates between background segmentation and heel effect correction until convergence. We illustrate the performance of the method on flat field and phantom images and demonstrate its robustness on a database of 137 diagnostic hand radiographs. © Springer-Verlag Berlin Heidelberg 2001.

关键词： Radiography

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Very fast soft tissue predictions with mass tensor model for maxillofacial surgery planning systems

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International Congress Series 2005年 1281卷 491-496页

作者： Mollemans, Wouter Schutyser, Filip Nadjmi, Nasser Suetens, Paul Medical Image Computing (Radiology-ESAT/PSI) University Hospital Gasthuisberg B-3000 Leuven Herestraat 4 Belgium Eeuwfeestkliniek 2018 Antwerpen Harmoniestraat 68 Belgium

Maxillofacial surgery treats abnormalities of the skeleton of the head. Skull remodelling implies osteotomies, bone fragment repositioning, restoration of bone defects and inserting implants. In this field there is a huge demand from the surgeons to be able to predict the new facial outlook after surgery. Besides the big interests for the surgeon during planning, it is also an essential tool to improve the communication between surgeon and patient. Mass Spring Models (MSM) are widely used to simulate the deformation behavior of soft tissues. The usage of these models has however some serious disadvantages. Most important is that the MSM has no real bio-mechanical foundation. The Finite Element Model (FEM) on the other hand has a strong bio-mechanical foundation but the high computational cost and a difficult architecture make it not very useful for fast simulators. In this paper we present the usage of a Mass Tensor Model (MTM) to simulate the soft tissue deformations after bone displacement. This model tries to combine the advantages of FEM and MSM. Moreover by combining this MTM with a new static solution scheme and a dynamic threshold, we were able to reduce the calculation time seriously when compared to MSM or FEM. © 2005 CARS and Elsevier B.V.

关键词： Mass tensor Maxillofacial Planning systems Soft tissue modelling

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Voxel based nonrigid image registration using local and partial volume similarity measures

Voxel based nonrigid image registration using local and part...

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IEEE International Symposium on Biomedical Imaging

作者： D. Loeckx F. Maes D. Vandermeulen P. Suetens Medical Image Computing ESAT/PSI Katholieke Universiteit Leuven Belgium

ISBN: (纸本)9781424441259;9781424441266

Recently, different approaches have emerged for voxel based nonrigid image registration using local instead of global similarity measures. Benefits are more accurate registration or the ability to subdivide the global similarity in local contributions. Within this article, we provide a general method to localise similarity measures using overlapping regions. Moreover, we extend the concept of partial volume estimation, introduced for mutual information (MI), to other similarity measures. We compare local and global sum of squared differences (SSD), cross correlation (CC) and MI for different sizes of the local regions. In general, local MI gives the highest accuracy, even for image pairs of the same modality. Partial volume estimation slightly improves the accuracy for local measures; the improvement is more pronounced for label images.

关键词： image registration Volume measurement Mutual information Pressure measurement Biomedical imaging Measurement standards Histograms Interpolation image databases

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Robust and accurate partial surface registration based on variational implicit surfaces for automatic 3D model building

Robust and accurate partial surface registration based on va...

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International Conference on 3D Imaging, Modeling, Processing, Visualization and Transmission (3DIMPVT)

作者： P. Claes D. Vandermeulen L. Van Gool P. Suetens ESAT/PSI/Medical Image Computing Katholieke Universiteit Leuven Belgium ESAT/PSI/VISICS Katholieke Universiteit Leuven Belgium

Three-dimensional models are often assembled from several partial reconstructions from unknown viewpoints. In order to provide a fully automatic, robust and accurate method for aligning and integrating partial reconstructions without any prior knowledge of the relative viewpoints of the sensor or the geometry of the imaging process, we propose a 4-step registration and integration algorithm based on a common Variational Implicit Surface (VIS) representation of the partial surface reconstructions. First, a global crude registration without a priori knowledge is performed followed by a pose refinement of partial reconstruction pairs. Pair-wise registrations are converted into a multi-view registration, before a final integration of the reconstructions into one entity or model occurs. Furthermore, making use of the smoothing properties of the VIS representations, the algorithm proves to be robust against noise in the reconstruction data. Experimental results on real-live, as well as noiseless and noisy simulated data are presented to show the feasibility, the accuracy and robustness of our registration scheme.

关键词： image reconstruction Surface reconstruction Biomedical imaging Geometry Smoothing methods Noise robustness Cameras image sensors Assembly systems Calibration

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Partial surface integration based on variational implicit functions and surfaces for 3D model building

Partial surface integration based on variational implicit fu...

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International Conference on 3D Imaging, Modeling, Processing, Visualization and Transmission (3DIMPVT)

作者： P. Claes D. Vandermeulen L. Van Gool P. Suetens ESAT/PSI/Medical Image Computing Katholieke Universiteit Leuven Belgium ESAT/PSI/VISICS Katholieke Universiteit Leuven Belgium

Most three-dimensional acquisition systems generate several partial reconstructions that have to be registered and integrated for building a complete 3D model. In this paper, we propose a volumetric shape integration method, consisting of weighted signed distance functions represented as variational implicit functions (VIF) or surfaces (VIS). Texture integration is solved similarly by using three weighted color junctions also based on VIFs. Using these continuous (not grid-based) representations solves current limitations of volumetric methods: no memory inefficient and resolution limiting grid representation is required. The built-in smoothing properties of the VIS representations also improve the robustness of the final integration against noise in the input data. Experimental results are performed on real-live, noiseless and noisy synthetic data of human faces in order to show the robustness and accuracy of the integration algorithm.

关键词： Biomedical imaging image reconstruction Shape Noise robustness Data mining Surface reconstruction Colored noise Smoothing methods Humans Face

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Validation of different soft tissue simulation methods for breast augmentation

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International Congress Series 2005年 1281卷 485-490页

作者： Roose, Liesbet De Maerteleire, Wim Mollemans, Wouter Suetens, Paul Medical Image Computing (Radiology and ESAT/PSI) Faculties of Medicine and Engineering University Hospital Gasthuisberg Leuven B-3000 Herestraat 49 Belgium 3D Medical BV Eindhoven 5615 PE Keizer Karel V Singel 14 Netherlands

In spite of the large number of breast reconstruction and breast augmentation procedures, there exists no reliable simulation method to predict the patient-specific surgical outcome of breast augmentation. In this paper, we present a computational model capable of simulating the postoperative shape of the breast up to 1 cm accuracy after a subglandular breast implantation. In particular, we compare a mass spring system with a finite element model, we investigate the influence of different elasticity models, and we examine which imaging modalities are suited to generate the patient specific data. © 2005.

关键词： Augmentation mammoplasty Mass spring system Soft tissue simulation Surgery planning

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Tight integration of a commercial PACS viewer as a component within a multimedia clinical viewing station

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International Congress Series 2001年第C期1230卷 812-819页

作者： Bellon, Erwin Feron, Michel Vanautgaerden, Mark Aerts, Werner Suetens, Paul Marchal, Guy Van den Bosch, Bart Department of Information Systems University Hospitals Leuven B-3000 Leuven Herestraat 49 Belgium Medical Image Computing (ESAT/PSI and Radiology) Katholieke Universiteit Leuven Leuven Belgium Department of Radiology University Hospitals Leuven Leuven Belgium

We claim that to deploy PACS in large-scale clinical routine, image access and viewing must be tightly integrated within the overall user interface of the multimedia clinical workstation. First, we motivate the need for integration. Then, we propose minimal requirements for an image viewer to be integrated in a clinical workstation. Finally, we report on initial experience with integration of a commercial viewer, in developments that are part of the clinical PACS project at the University Hospitals Leuven, with emphasis on technology for integration. We discuss the aspect of integration within the broader context of PACS, and point to a potential risk for the Radiological PACS community to ignore emerging trends in building large information systems. © 2001, Elsevier B.V. All rights reserved.

关键词： Clinical workstation HIS-PACS integration image access Information system PACS

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