The prediction of gene function from genome sequences is one of the main issues in Bioinformatics. Most computational approaches are based on the similarity between sequences to infer gene function. However, the avail...
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The prediction of gene function from genome sequences is one of the main issues in Bioinformatics. Most computational approaches are based on the similarity between sequences to infer gene function. However, the availability of several fully sequenced genomes has enabled alternative approaches, such as phylogenetic profiles. Phylogenetic profiles are vectors which indicate the presence or absence of a gene in other genomes. The main concept of phylogenetic profiles is that proteins participating in a common structural complex or metabolic pathway are likely to evolve in a correlated fashion. In this paper, a multi level clustering algorithm of phylogenetic profiles is presented, which aims to detect inter- and intra-genome gene clusters.
With the advance of semiconductor, multi-core architecture is inevitable in today's embedded system design. Nested loops are usually the most critical part in multimedia and high performance DSP (Digital Signal Pr...
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One of the prominent principles of designing services is the matter of how abstract services should be i.e. granularity. Since service-oriented analysis and design methods lack on providing a quantitative model for se...
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One of the prominent principles of designing services is the matter of how abstract services should be i.e. granularity. Since service-oriented analysis and design methods lack on providing a quantitative model for service granularity level evaluation, identification of optimally granular services is the key challenge in service-oriented solution development. This article through a systematic process proposes a model namely Weighted Granularity Level Appropriateness (WGLA) which leverages and consolidates four metrics to constitute quantitative basis for granularity appropriateness analysis. These metrics are, indeed, the four quantified attributes of service granularity including business value, reusability, context-independency, and complexity. Our preliminary controlled experiment confirms the correctness of the quantitative model. In fact, by adopting WGLA metric, service granularity appropriateness analysis could be conduct quantitatively that leads to realize an optimized service-oriented solution in terms of its granularity.
This special session aims to introduce to the hardware/software codesign community challenges and opportunities in designing high performance computing (HPC) systems. Though embedded system design and HPC system desig...
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ISBN:
(纸本)9781605589053
This special session aims to introduce to the hardware/software codesign community challenges and opportunities in designing high performance computing (HPC) systems. Though embedded system design and HPC system design have traditionally been considered as two separate areas of research, they in fact share quite some common features, especially as CMOS devices continue along their scaling trends and the HPC community hits hard power and energy limits. Understanding the similarities and differences between the design practices adopted in the two areas will help bridge the two communities and lead to design tool developments benefiting both communities.
Power and fault tolerance are deemed to be two orthogonal optimization objectives in FPGA synthesis, with independent attempts to develop algorithms and CAD tools to optimize each objective. In this paper, we study th...
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ISBN:
(纸本)9781424481927
Power and fault tolerance are deemed to be two orthogonal optimization objectives in FPGA synthesis, with independent attempts to develop algorithms and CAD tools to optimize each objective. In this paper, we study the relationship between these two optimizations and show empirically that there are strong ties between them. Specifically, we analyze the power and reliability optimization problems in FPGA physical synthesis (i.e., packing, placement, and routing), and show that the intrinsic structures of these two problems are very similar. Supported by the post routing results with detailed power and reliability analysis for a wide selection of benchmark circuits, we show that with minimal changes - fewer than one hundred lines of C code - an existing power-aware physical synthesis tool can be used to minimize the fault rate of a circuit under SEU faults. As a by-product of this study, we also show that one can improve the mean-time-to-failure by 100% with negligible area and delay overhead by performing fault-tolerant physical synthesis for FPGAs. The results from this study show a great potential to develop CAD systems co-optimized for power and fault-tolerance.
Timed failure propagation graph (TFPG) is a directed graph model that represents temporal progression of failure effects in physical systems. In this paper, a distributed diagnosis approach for complex systems is intr...
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Timed failure propagation graph (TFPG) is a directed graph model that represents temporal progression of failure effects in physical systems. In this paper, a distributed diagnosis approach for complex systems is introduced based on the TFPG model settings. In this approach, the system is partitioned into a set of local subsystems each represented by a subgraph of the global system TFPG model. Information flow between subsystems is achieved through special input and output nodes. A high level diagnoser integrates the diagnosis results of the local subsystems using an abstract high level model to obtain a globally consistent diagnosis of the system.
This special session aims to introduce to the hardware/software codesign community challenges and opportunities in designing high performance computing (HPC) systems. Though embedded system design and HPC system desig...
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Recently, cluster synchronization has attracted an increasing interest in various disciplines, including mathematics, physics, and engineering sciences. This paper further investigates the cluster synchronization of a...
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ISBN:
(纸本)9781424464500;9781424464531
Recently, cluster synchronization has attracted an increasing interest in various disciplines, including mathematics, physics, and engineering sciences. This paper further investigates the cluster synchronization of a complex dynamical network by using adaptive and impulsive control techniques, respectively. Based on a complex dynamical network with two different clusters, several adaptive and impulsive cluster synchronization criteria are then proposed. It should be especially pointed out that the dynamics and its dimensions of the individual dynamical systems are different in the two different clusters. Also, some numerical simulations are given to verify the effectiveness of the above theoretical results.
This paper describes different proposals made at UNED, for post-graduated students, at the area of IT Services Management and specially trying to fill the gap, of paramount importance, of the treatment due in ITIL ...
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This paper describes different proposals made at UNED, for post-graduated students, at the area of IT Services Management and specially trying to fill the gap, of paramount importance, of the treatment due in ITIL ® (Information Technology Infrastructure Library) to Information Security Management. We analyze the treatment given to Information Security Management in ITIL, both versions 2 and 3, and describe the different at distance post-graduated courses we offer that fill these methodologies and discuss the opinions and evaluations of our students.
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