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Erratum to: Robot-assisted modifications of gait in healthy individuals

Experimental Brain Research 2010年第4期202卷 943-943页

作者： Kim, Seok Hun Banala, Sai K. Brackbill, Elizabeth A. Agrawal, Sunil K. Krishnamoorthy, Vijaya Scholz, John P. School of Physical Therapy and Rehabilitation Sciences University of South Florida Tampa USA Department of Mechanical Engineering University of Delaware Newark USA Division of Physical Therapy Department of Rehabilitation Medicine Emory University Atlanta USA Department of Physical Therapy University of Delaware Newark USA Biomechanics and Movement Science Program University of Delaware Newark USA

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Fatigue and non-fatigue mathematical muscle models during functional electrical stimulation of paralyzed muscle

Fatigue and non-fatigue mathematical muscle models during fu...

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作者： Cai, Zhijun Bai, Er-Wei Shield, Richard K. Electrical and Computer Engineering University of Iowa Iowa City IA 52242 United States Graduate Program in Physical Therapy and Rehabilitation Science University of Iowa Iowa City IA 52242 United States

ISBN: (纸本)9783902661494

electrical muscle stimulation demonstrates potential for restoring functional movement and for preventing muscle atrophy after spinal cord injury (SCI). To optimize delivery of electrical stimulation protocols, an accurate and easy-to-implement mathematical skeletal muscle model is essential. The existing models are either accurate but complex, making them hard to implement, such as the Hill-Huxley-type model, or simple but inaccurate, such as second order model. In this paper, we propose a Wiener-Hammerstein system to model the paralyzed skeletal muscle dynamics under electrical stimulus conditions. The proposed model has substantial advantages in identification algorithm analysis and implementation including computational complexity and convergence. Experimental data sets were collected on soleus muscles under 15 Hz frequency stimulation for fourteen subjects with SCI. The simulation results show that the proposed model outperforms the Hill-Huxley-type model not only in peak force prediction, but also in fitting performance for force output of each individual stimulation train. © 2009 IFAC.

关键词： Muscle

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Ontology engineering

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Nature Biotechnology 2010年第2期28卷 128-130页

作者： Alterovitz, Gil Xiang, Michael Hill, David P. Lomax, Jane Liu, Jonathan Cherkassky, Michael Dreyfuss, Jonathan Mungall, Chris Harris, Midori A. Dolan, Mary E. Blake, Judith A. Ramoni, Marco F. Children's Hospital Informatics Program Harvard-MIT Division of Health Sciences and Technology Harvard Medical School Boston MA United States Partners Healthcare Center for Personalized Genetic Medicine Boston MA United States Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge MA United States Jackson Laboratory Bar Harbor ME United States EMBL-EBI Wellcome Trust Genome Campus Hinxton United Kingdom Department of Biology Massachusetts Institute of Technology Cambridge MA United States Lawrence Berkeley National Laboratory Berkeley CA United States

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Constraints on dark matter models from a Fermi LAT search for high-energy cosmic-ray electrons from the Sun

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physical Review D 2011年第3期84卷 032007-032007页

作者： M. Ajello W. B. Atwood L. Baldini G. Barbiellini D. Bastieri R. Bellazzini B. Berenji R. D. Blandford E. D. Bloom E. Bonamente A. W. Borgland E. Bottacini A. Bouvier J. Bregeon M. Brigida P. Bruel R. Buehler S. Buson G. A. Caliandro R. A. Cameron P. A. Caraveo C. Cecchi E. Charles A. Chekhtman S. Ciprini R. Claus J. Cohen-Tanugi S. Cutini A. de Angelis F. de Palma C. D. Dermer S. W. Digel E. do Couto e Silva P. S. Drell C. Favuzzi S. J. Fegan W. B. Focke Y. Fukazawa P. Fusco F. Gargano N. Gehrels S. Germani N. Giglietto F. Giordano M. Giroletti T. Glanzman G. Godfrey I. A. Grenier S. Guiriec M. Gustafsson D. Hadasch G. Iafrate G. Jóhannesson A. S. Johnson T. Kamae H. Katagiri J. Kataoka M. Kuss L. Latronico A. M. Lionetto F. Longo F. Loparco M. N. Lovellette P. Lubrano M. N. Mazziotta J. E. McEnery P. F. Michelson T. Mizuno C. Monte M. E. Monzani A. Morselli I. V. Moskalenko S. Murgia M. Naumann-Godo J. P. Norris E. Nuss T. Ohsugi N. Omodei E. Orlando J. F. Ormes M. Ozaki D. Paneque J. H. Panetta M. Pesce-Rollins M. Pierbattista F. Piron S. Rainò R. Rando M. Razzano A. Reimer O. Reimer S. Ritz T. L. Schalk C. Sgrò J. Siegal-Gaskins E. J. Siskind P. D. Smith G. Spandre P. Spinelli D. J. Suson H. Takahashi T. Tanaka J. G. Thayer J. B. Thayer L. Tibaldo G. Tosti E. Troja T. L. Usher J. Vandenbroucke V. Vasileiou G. Vianello N. Vilchez A. P. Waite P. Wang B. L. Winer K. S. Wood Z. Yang S. Zimmer W. W. Hansen Experimental Physics Laboratory Kavli Institute for Particle Astrophysics and Cosmology Department of Physics and SLAC National Accelerator Laboratory Stanford University Stanford California 94305 USA Santa Cruz Institute for Particle Physics Department of Physics and Department of Astronomy and Astrophysics University of California at Santa Cruz Santa Cruz California 95064 USA Istituto Nazionale di Fisica Nucleare Sezione di Pisa I-56127 Pisa Italy Istituto Nazionale di Fisica Nucleare Sezione di Trieste I-34127 Trieste Italy Dipartimento di Fisica Università di Trieste I-34127 Trieste Italy Istituto Nazionale di Fisica Nucleare Sezione di Padova I-35131 Padova Italy Dipartimento di Fisica “G. Galilei ” Università di Padova I-35131 Padova Italy Istituto Nazionale di Fisica Nucleare Sezione di Perugia I-06123 Perugia Italy Dipartimento di Fisica Università degli Studi di Perugia I-06123 Perugia Italy Dipartimento di Fisica “M. Merlin” dell’Università e del Politecnico di Bari I-70126 Bari Italy Istituto Nazionale di Fisica Nucleare Sezione di Bari 70126 Bari Italy Laboratoire Leprince-Ringuet École polytechnique CNRS/IN2P3 Palaiseau France Institut de Ciències de l’Espai (IEEE-CSIC) Campus UAB 08193 Barcelona Spain INAF-Istituto di Astrofisica Spaziale e Fisica Cosmica I-20133 Milano Italy Artep Inc. 2922 Excelsior Springs Court Ellicott City Maryland 21042 USA and resident at Naval Research Laboratory Washington D.C. 20375 USA ASI Science Data Center I-00044 Frascati (Roma) Italy Laboratoire Univers et Particules de Montpellier Université Montpellier 2 CNRS/IN2P3 Montpellier France Agenzia Spaziale Italiana (ASI) Science Data Center I-00044 Frascati (Roma) Italy Dipartimento di Fisica Università di Udine and Istituto Nazionale di Fisica Nucleare Sezione di Trieste Gruppo Collegato di Udine I-33100 Udine Italy Space Science Division Naval Research Laboratory Washington D.C. 20375-5352 USA Department of Physical Sciences Hiroshima

During its first year of data taking, the Large Area Telescope (LAT) onboard the Fermi Gamma-Ray Space Telescope has collected a large sample of high-energy cosmic-ray electrons and positrons (CREs). We present the results of a directional analysis of the CRE events, in which we searched for a flux excess correlated with the direction of the Sun. Two different and complementary analysis approaches were implemented, and neither yielded evidence of a significant CRE flux excess from the Sun. We derive upper limits on the CRE flux from the Sun’s direction, and use these bounds to constrain two classes of dark matter models which predict a solar CRE flux: (1) models in which dark matter annihilates to CREs via a light intermediate state, and (2) inelastic dark matter models in which dark matter annihilates to CREs.

关键词： TELESCOPES FERMI Gamma-ray Space Telescope (Spacecraft) COSMIC rays ELECTRON-positron interactions LEPTON interactions POSITRONS

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Stochastic approach on a simplified OCC model for uncertainty and believability

Stochastic approach on a simplified OCC model for uncertaint...

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IEEE International Symposium on Computational Intelligence in Robotics and Automation (CIRA)

作者： Won Hwa Kim Jeong Woo Park Won Hyong Lee Woo Hyun Kim Myung Jin Chung Robotics Program KAIST Daejeon South Korea School of Electrical Engineering and Computer Science Division of Electrical Engineering KAIST Daejeon South Korea

ISBN: (纸本)9781424448081

As robots step into the human's daily lives, interaction and communication between human and robot is becoming essential. For this social interaction with humans, we propose an emotion generation model considering simplicity, believability and uncertainty. First, OCC model is simplified and then stochastic approach on emotion decision algorithm for believability and uncertainty is applied. The proposed model is implemented on a 3D robot expression simulator that can express emotions through its facial expression, gesture, led and so on. A demo of the model is provided as a result.

关键词： Stochastic processes Uncertainty Cognitive robotics Human robot interaction Intelligent robots Electronic mail Databases Atherosclerosis Humanoid robots Computational modeling

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Comparison of threshold selection methods for microarray gene co-expression matrices

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BMC Research Notes 2009年第1期2卷 1-6页

作者： Borate, Bhavesh Chesler, Elissa Langston, Michael Saxton, Arnold Voy, Brynn Genome Science and Technology Program University of Tennessee Knoxville TN United States Department of Electrical Engineering and Computer Science University of Tennessee Knoxville TN United States Oak Ridge National Laboratory Systems Genetics Group Biosciences Division Oak Ridge TN United States Department of Animal Science University of Tennessee Knoxville TN United States

Background. Network and clustering analyses of microarray co-expression correlation data often require application of a threshold to discard small correlations, thus reducing computational demands and decreasing the number of uninformative correlations. This study investigated threshold selection in the context of combinatorial network analysis of transcriptome data. Findings. Six conceptually diverse methods - based on number of maximal cliques, correlation of control spots with expressed genes, top 1% of correlations, spectral graph clustering, Bonferroni correction of p-values, and statistical power - were used to estimate a correlation threshold for three time-series microarray datasets. The validity of thresholds was tested by comparison to thresholds derived from Gene Ontology information. Stability and reliability of the best methods were evaluated with block bootstrapping. Two threshold methods, number of maximal cliques and spectral graph, used information in the correlation matrix structure and performed well in terms of stability. Comparison to Gene Ontology found thresholds from number of maximal cliques extracted from a co-expression matrix were the most biologically valid. Approaches to improve both methods were suggested. Conclusion. Threshold selection approaches based on network structure of gene relationships gave thresholds with greater relevance to curated biological relationships than approaches based on statistical pair-wise relationships. © 2009 Saxton et al;licensee BioMed Central Ltd.

关键词： Spectral Cluster Maximal Clique Threshold Estimate Biological Relationship Spectral Graph

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Corrigendum to “Measurement of resonance frequency and loss factor of a microphone diaphragm using a laser vibrometer” [Appl. Acoust. 71 (2010) 258–261]

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Applied Acoustics 2010年第7期71卷 681-681页

作者： Jae Gap Suh Hack-Yoon Kim Yôiti Suzuki Division of Physical Metrology Korea Research Institute of Standards and Science 1 Doryong-Dong Yuseong-Gu Daejeon 305-340 Republic of Korea Department of Electronic Engineering Cheongju University 36 Naeduk-Dong Cheongju Republic of Korea Research Institute of Electrical Communication Tohoku University Katahira 2-1-1 Aoba-Ku Sandai 980-8577 Japan

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Fatigue and Non-Fatigue Mathematical Muscle Models During Functional electrical Stimulation of Paralyzed Muscle

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IFAC Proceedings Volumes 2009年第12期42卷 365-370页

作者： Zhijun Cai Er-Wei Bai Richard K. Shield Electrical and Computer Engineering The University of Iowa Iowa City IA 52242USA Graduate Program in Physical Therapy and Rehabilitation Science The University of Iowa Iowa City IA 52242 USA

关键词： modeling identification muscle modeling fatigue modeling

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He ion irradiation damage in Al/Nb multilayers

He ion irradiation damage in Al/Nb multilayers

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作者： Li, Nan Martin, M.S. Anderoglu, O. Misra, A. Shao, L. Wang, H. Zhang, X. Department of Mechanical Engineering Materials Science and Engineering Program Texas A and M University College Station TX 77843-3123 United States Department of Nuclear Engineering Texas A and M University College Station TX 77843-3133 United States Materials Physics and Application Division Los Alamos National Laboratory Los Alamos NM 87545 United States Department of Electrical and Computer Engineering Texas A and M University College Station TX 77843-3128 United States

We investigate the evolution of microstructure and mechanical properties of sputter-deposited Al/Nb multilayers with miscible fcc/bcc type interface and individual layer thickness, h, of 1-200 nm, subjected to helium ion irradiations: 100 keV He+ ions and a fluence of 6 10 16/cm2. Helium bubbles, 1-2 nm in diameter, are observed. When h is greater than 25 nm, hardnesses of irradiated multilayers barely change, whereas radiation hardening is more significant at smaller h. Transmission electron microscopy and scanning transmission electron microscopy studies reveal the formation of a thin layer of Nb3 Al intermetallic phase along the Al/Nb interface as a consequence of radiation induced intermixing. The dependence of radiation hardening on h is interpreted by using a composite model considering the formation of the hard Nb3 Al intermetallic layer. © 2009 American Institute of Physics.

关键词： High resolution transmission electron microscopy

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Simultaneous temperature and magnetization transfer (MT) monitoring during high-intensity focused ultrasound (HIFU) treatment: Preliminary investigation on ex vivo porcine muscle

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Journal of Magnetic Resonance Imaging 2009年第3期30卷 596-605页

作者： Peng, Hsu-Hsia Huang, Teng-Yi Tseng, Wen-Yih Isaac Lin, En-Li Chung, Hsiao-Wen Wu, Chih-Ching Wang, Yu-Shun Chen, Wen-Shiang Department of Biomedical Engineering and Environmental Sciences National Tsing Hua University Hsinchu Taiwan Department of Electrical Engineering National Taiwan University of Science and Technology Taipei 106 No. 43 Sec.4 Keelung Rd. Taiwan Center for Optoelectronic Biomedicine National Taiwan University College of Medicine Taipei Taiwan Department of Medical Imaging National Taiwan University Hospital Taipei Taiwan Department of Electrical Engineering National Taiwan University Taipei Taiwan Department of Mechanical Engineering National Taiwan University Taipei Taiwan Division of Medical Engineering Research National Health Research Institutes Miaoli Taiwan Department of Physical Medicine and Rehabilitation National Taiwan University Hospital Taipei Taiwan

Purpose: To measure temperature change and magnetization transfer ratio (MTR) simultaneously during high-intensity focused ultrasound (HIFU) treatment. Materials and Methods: This study proposed an inter-leaved dual gradient-echo technique to monitor the heat and tissue damage brought to the heated tissue. The technique was applied to tissue samples to test its efficacy. Results: Ex vivo experiments on the porcine muscle demonstrated that both temperature changes and MTR exhibited high consistency in localizing the heated regions. As the heat dissipated after the treatment, the temperature of the heated regions decreased rapidly but MTR continued to be elevated. Moreover, thermal dose (TD) maps derived from the temperature curves demonstrated a sharp margin in the heated regions, but MTR maps may show a spatial gradient of tissue damage, suggesting complimentary information provided by these two measures. Conclusion: In a protocol of spot-by-spot heating over a large volume of tissue, MTR provides additional values to mark the locations of previously heated regions. By continuously recording the locations of heated spots, MTR maps could help plan the next target spots appropriately, potentially improving the efficiency of HIFU treatment and reducing undesirable damage to the normal tissue. © 2009 Wiley-Liss, Inc.

关键词： High-intensity focused ultrasound Magnetization transfer Temperature Thermal dose Thermotherapy Tissue damage

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