The Microelectronics WebLab at mit allows students to do actual (not simulated) laboratory research on state-of-the art equipment through the Internet. This study assesses the use of WebLab in a junior-level course on...
详细信息
Indium antimonide (InSb) is a promising material for mid- and long-wavelength infrared device applications. However, because of material's small band gap and low melting point, reproducibility of high quality epit...
详细信息
Magnetic relaxation switches (MRS) are being developed for local monitoring of cancer biomarkers. MRS are functionalized magnetic iron oxide nanoparticles that exhibit analyte-induced aggregation and a corresponding c...
详细信息
ISBN:
(纸本)1420061836
Magnetic relaxation switches (MRS) are being developed for local monitoring of cancer biomarkers. MRS are functionalized magnetic iron oxide nanoparticles that exhibit analyte-induced aggregation and a corresponding change in transverse spin-spin relaxation time (T2), which can be measured though NMR spectroscopy or MRI. MRS were functionalized with a matched pair of antibodies to detect the beta subunit of human chorionic gonadotrophin (hCG), which is elevated in testicular and ovarian cancers. These MRS have been shown to aggregate specifically in the presence of the hCG-β and hCG in a concentration dependent manner as confirmed by T2 changes and particle sizing measurements. Here, we report further characterization of this sensor system. The aggregates were found to dissociate with the addition of large excesses of hCG as governed by the dissociation constant of the antibodies. The effect of valency on the formation of aggregates was also studied.
We report on the optical study of efficient excitation transfer in organic-inorganic hybrid thin films composed of alternating monolayers of CdSe/ZnS QDs and J-aggregate of cyanine dyes, by steady-state and time-resol...
详细信息
We show how to determine the time to contact from time varying images using only accumulated sums of suitable products of image brightness derivatives. There is no need for feature or object detection, tracking of fea...
详细信息
We show how to determine the time to contact from time varying images using only accumulated sums of suitable products of image brightness derivatives. There is no need for feature or object detection, tracking of features, estimation of optical flow, or any "higher level" processing. This so-called "direct" method for determining the time to contact is based on analysis of the motion field resulting from rigid body motion under perspective projection and the constant brightness assumption. The method has essentially no latency, since it can be based on analysis of just two frames of a video sequence, and does not require a calibrated camera. An implementation of the method is demonstrated on synthetic image sequences and stop motion sequences - where the ground truth is accurately know - as well as on video sequences taken by a camera mounted on moving vehicles.
This work investigates the analysis of transient noise in non steady-state systems such as comparator-based switched-capacitor circuits. It expands the impulse sensitivity method previously applied to oscillator noise...
详细信息
This work investigates the analysis of transient noise in non steady-state systems such as comparator-based switched-capacitor circuits. It expands the impulse sensitivity method previously applied to oscillator noise analysis to general linear time varying systems. The method described here uses simulation techniques to obtain the noise transfer function. This provides a useful tool for circuit design because it allows for the precision and ease of simulation without sacrificing the intuition of hand calculations.
This paper reports the performance of a fully-integrated planar electrospray thruster array. Electrospray thrusters work by electrostatically extracting and accelerating ions or charged droplets from a liquid surface ...
详细信息
ISBN:
(纸本)1563479036
This paper reports the performance of a fully-integrated planar electrospray thruster array. Electrospray thrusters work by electrostatically extracting and accelerating ions or charged droplets from a liquid surface to produce thrust. Emission occurs from sharp emitter tips, which enhance the electric field and constrain the emission location. Electrospray propulsion is desirable for its simplicity, high thrust efficiency and tunable specific impulse. However, the electrospray process limits the thrust from a single tip, so that achieving millinewton thrust levels would require an array with tens of thousands of emitters. We have used silicon batch microfabrication technology to make an array of 502 emitters in a 113 mm2 area. The thruster, weighing 5 g, was tested with the ionic liquid EMI-BF4. Time of night measurements show that the thruster operates in the ion-emission regime, which is most efficient for propulsion, with a specific impulse around 3000 s at a 1 kV extractor voltage. Emission starts as low as 500 V. Currents of 370 nA per emitter have been recorded at 1500 V, for an estimated thrust of 26 nN per emitter or 13 μN total, and a 275 mW power consumption. The thrust efficiency is estimated around 85%. In good operating conditions, the current intercepted on the extractor electrode is well below 1%, increasing to a few percent at the highest current levels.
We report on the optical study of efficient excitation transfer in organic-inorganic hybrid thin films composed of alternating monolayers of CdSe/ZnS QDs and J-aggregate of cyanine dyes, by steady-state and time-resol...
详细信息
ISBN:
(纸本)9781424435906
We report on the optical study of efficient excitation transfer in organic-inorganic hybrid thin films composed of alternating monolayers of CdSe/ZnS QDs and J-aggregate of cyanine dyes, by steady-state and time-resolved photoluminescence spectroscopy study.
The state-of-the-art monitoring systems for critical care measure vital signs and generate alerts based on the logic of general patient population models, but they lack the capabilities of accurately correlating physi...
详细信息
The state-of-the-art monitoring systems for critical care measure vital signs and generate alerts based on the logic of general patient population models, but they lack the capabilities of accurately correlating physiological data with clinical events and of adapting to individual patient's characteristics that do not fit the population models. This research examines the feasibility of developing patient-specific alarm algorithms in real time at the bedside and evaluates the potential of these algorithms in helping improve patient monitoring. Modular components that facilitate real-time development of alarm algorithms were added to a system that simultaneously collects physiological data and clinical annotations at the bedside. At a pediatric intensive care unit (ICU), classification trees and neural networks for generating clinical alarms were trained for individual patients. These algorithms were evaluated immediately after training on subsequently collected data. The implemented system was capable of training and evaluating patient-specific algorithms in a consistent manner in real time at the bedside. The performance of patient-specific alarm algorithms improved as training data increased. Neural networks with eight hours of training data on average achieved a sensitivity of 0.96, a specificity of 0.99, a positive predictive value of 0.79, and an accuracy of 0.99;these figures were 0.84, 0.98, 0.72, and 0.98 respectively for the classification trees. These results suggest that real-time development of patient-specific alarm algorithms is feasible using machine learning techniques. The patient-specific alarm algorithms developed in this study outperformed the bedside monitors from a decade ago and came close in performance to the new generation of monitors.
暂无评论